(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Sheep Diseases D012757 10 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Intestinal Diseases D007410 6 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Brain Neoplasms D001932 15 associated lipids
Hypothyroidism D007037 32 associated lipids
Uterine Diseases D014591 6 associated lipids
Weight Gain D015430 101 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cholestasis D002779 23 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Hypoglycemia D007003 13 associated lipids
Metabolic Diseases D008659 12 associated lipids
Starvation D013217 47 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Hypocalcemia D006996 12 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Abu-Elheiga L et al. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. 2001 Science pmid:11283375
McGarry JD What if Minkowski had been ageusic? An alternative angle on diabetes. 1992 Science pmid:1439783
Shimazu T et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 2013 Science pmid:23223453
Sassone-Corsi P Physiology. When metabolism and epigenetics converge. 2013 Science pmid:23307727
Davis JD et al. Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats. 1981 Science pmid:7193909
Gutzwiller A [Determination of beta-hydroxybutyrate in milk using test strips: a new aid for the diagnosis of subclinical and clinical ketosis in the cow]. 1998 Schweiz. Arch. Tierheilkd. pmid:9528350
Hässig M et al. [Benefit of clinical and laboratory parameters for the diagnosis of endometritis in dairy cows]. 2010 Schweiz. Arch. Tierheilkd. pmid:20814859
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Svedman C et al. Skin mini-erosion technique for monitoring metabolites in interstitial fluid: its feasibility demonstrated by OGTT results in diabetic and non-diabetic subjects. 1999 Scand. J. Clin. Lab. Invest. pmid:10353325
Christensen CK et al. Effect of 3-hydroxybutyrate infusion on urinary protein excretion in healthy man. 1986 Scand. J. Clin. Lab. Invest. pmid:3520791
Hallas J The association between calcium and acetoacetate, 3-hydroxybutyrate, pyruvate and lactate as determined by potentiometry. Determination of concentrational complexity constants in watery solutions at physiological conditions. 1987 Scand. J. Clin. Lab. Invest. pmid:3672031
Taskinen MR et al. Lipoprotein lipase activity in adipose tissue and skeletal muscle of human diabetics during insulin deprivation and restoration. 1981 Scand. J. Clin. Lab. Invest. pmid:7031837
Haakens K et al. Early morning glycaemia and the metabolic consequences of delaying breakfast/morning insulin. A comparison of continuous subcutaneous insulin infusion and multiple injection therapy with human isophane or human ultralente insulin at bedtime in insulin-dependent diabetics. 1989 Scand. J. Clin. Lab. Invest. pmid:2692136
Szabó Z et al. Myocardial uptake and release of substrates in type II diabetics undergoing coronary surgery. 2001 Scand. Cardiovasc. J. pmid:11515695
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Varela A et al. Effects of 3-hydroxybutyrate on the hypoxic and reoxygenated atria from fed and fasted rats. 1997 Rev. Esp. Fisiol. pmid:9542775
Mulier KE et al. Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock. 2012 Resuscitation pmid:21864484
Jakobsson EJ and Jorfeldt L Blood fuel metabolites at rest and during exercise in patients with advanced chronic obstructive pulmonary disease with and without chronic respiratory failure. 1990 Respiration pmid:2126638
Ghanem MM and El-Deeb WM Lecithin cholesterol acyltransferase (LCAT) activity as a predictor for ketosis and parturient haemoglobinuria in Egyptian water buffaloes. 2010 Res. Vet. Sci. pmid:19682715
Zebeli Q et al. Intermittently-induced endotoxaemia has no effect on post-challenge plasma metabolites, but increases body temperature and cortisol concentrations in periparturient dairy cows. 2013 Res. Vet. Sci. pmid:23911054
Mavrogianni VS et al. Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period. 2014 Res. Vet. Sci. pmid:24331730
Voyvoda H and Erdogan H Use of a hand-held meter for detecting subclinical ketosis in dairy cows. 2010 Res. Vet. Sci. pmid:20471047
Trevisi E et al. Metabolic stress and inflammatory response in high-yielding, periparturient dairy cows. 2012 Res. Vet. Sci. pmid:22197526
Maglad MA et al. Inhibition of glucose-induced insulin secretion by somatostatin in goats. 1983 Res. Vet. Sci. pmid:6137867
Álvarez-Rodríguez J et al. Rumen fermentation and histology in light lambs as affected by forage supply and lactation length. 2012 Res. Vet. Sci. pmid:21458834
Panousis N et al. Evaluation of Precision Xceed® meter for on-site monitoring of blood β-hydroxybutyric acid and glucose concentrations in dairy sheep. 2012 Res. Vet. Sci. pmid:21764413
Harmeyer J and Schlumbohm C Pregnancy impairs ketone body disposal in late gestating ewes: implications for onset of pregnancy toxaemia. 2006 Res. Vet. Sci. pmid:16427105
Todd SE et al. Effects of food withdrawal and transport on 5- to 10-day-old calves. 2000 Res. Vet. Sci. pmid:10756129
Lean IJ et al. Bovine ketosis and somatotrophin: risk factors for ketosis and effects of ketosis on health and production. 1994 Res. Vet. Sci. pmid:7817007
van der Drift SG et al. Effects of β-hydroxybutyrate and isoproterenol on lipolysis in isolated adipocytes from periparturient dairy cows and cows with clinical ketosis. 2013 Res. Vet. Sci. pmid:23256919
Schlumbohm C and Harmeyer J Twin-pregnancy increases susceptibility of ewes to hypoglycaemic stress and pregnancy toxaemia. 2008 Res. Vet. Sci. pmid:17610919
Brinkmann L et al. Effect of long-term feed restriction on the health status and welfare of a robust horse breed, the Shetland pony (Equus ferus caballus). 2013 Res. Vet. Sci. pmid:23141417
Knechtle B et al. No change of body mass, fat mass, and skeletal muscle mass in ultraendurance swimmers after 12 hours of swimming. 2009 Res Q Exerc Sport pmid:19408468
Hörl WH et al. The key role of sex dependency on kidney citrate metabolism in the rat. 1985 Res Exp Med (Berl) pmid:3969523
Schölmerich J et al. Effects of propylene glycol on redox state of the perfused rat liver--a note of caution. 1989 Res Exp Med (Berl) pmid:2711035
Marchetti P et al. Effect of cyclosporin treatment on metabolic and hormonal responses to mixed meal plus oral glucose in dogs with intrasplenic pancreatic islet autograft. 1994 Res Exp Med (Berl) pmid:8202638
Meikle A et al. Effects of parity and body condition at parturition on endocrine and reproductive parameters of the cow. 2004 Reproduction pmid:15175509
Freret S et al. Reduction of body-weight gain enhances in vitro embryo production in overfed superovulated dairy heifers. 2006 Reproduction pmid:16595729
Memon S and Pratten MK Teratogenic effects of diabetic conditions in chick heart in ovo and in micromass culture may be prevented by addition of vitamin C and folic acid. 2013 Reprod. Toxicol. pmid:23099339
Nozière P et al. Differences between blood and plasma concentrations of acetate, beta-hydroxybutyrate, glucose, ammonia and urea: implications for measurement of portal net fluxes in ewes. 1998 Sep-Oct Reprod. Nutr. Dev. pmid:9923003
Pérez-Clariget R et al. Influence of nutrition on testicular growth in Corriedale rams during spring. 1998 Sep-Oct Reprod. Nutr. Dev. pmid:9923005
Bas P et al. [Relationship of the level of energy ingestion and several blood parameters in kids during 2 weeks after weaning]. 1990 Reprod. Nutr. Dev. pmid:2206344
Clarke L et al. Effect of maternal glucose infusion on brown adipose tissue and liver development in the neonatal lamb. 1996 Reprod. Fertil. Dev. pmid:8916280
Vanholder T et al. Hormonal and metabolic profiles of high-yielding dairy cows prior to ovarian cyst formation or first ovulation post partum. 2005 Reprod. Domest. Anim. pmid:16149953
Senosy WS et al. Influences of metabolic traits on subclinical endometritis at different intervals postpartum in high milking cows. 2012 Reprod. Domest. Anim. pmid:22053752
Leroy JL et al. The in vitro development of bovine oocytes after maturation in glucose and beta-hydroxybutyrate concentrations associated with negative energy balance in dairy cows. 2006 Reprod. Domest. Anim. pmid:16519716
Vanholder T et al. Effects of beta-OH butyrate on bovine granulosa and theca cell function in vitro. 2006 Reprod. Domest. Anim. pmid:16420326