(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Sheep Diseases D012757 10 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Intestinal Diseases D007410 6 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Brain Neoplasms D001932 15 associated lipids
Hypothyroidism D007037 32 associated lipids
Uterine Diseases D014591 6 associated lipids
Weight Gain D015430 101 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cholestasis D002779 23 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Hypoglycemia D007003 13 associated lipids
Metabolic Diseases D008659 12 associated lipids
Starvation D013217 47 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Hypocalcemia D006996 12 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Gutzwiller A [Determination of beta-hydroxybutyrate in milk using test strips: a new aid for the diagnosis of subclinical and clinical ketosis in the cow]. 1998 Schweiz. Arch. Tierheilkd. pmid:9528350
Hässig M et al. [Benefit of clinical and laboratory parameters for the diagnosis of endometritis in dairy cows]. 2010 Schweiz. Arch. Tierheilkd. pmid:20814859
Abu-Elheiga L et al. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. 2001 Science pmid:11283375
McGarry JD What if Minkowski had been ageusic? An alternative angle on diabetes. 1992 Science pmid:1439783
Shimazu T et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 2013 Science pmid:23223453
Sassone-Corsi P Physiology. When metabolism and epigenetics converge. 2013 Science pmid:23307727
Davis JD et al. Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats. 1981 Science pmid:7193909
van Delft R et al. Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine. 2010 Seizure pmid:19962324
Soultanakis HN et al. Prolonged exercise in pregnancy: glucose homeostasis, ventilatory and cardiovascular responses. 1996 Semin. Perinatol. pmid:8888457
Wu S et al. [Intravascular biocompatibility of decellularized xenogenic vascular scaffolds/PHBHHx hybrid material for cardiovascular tissue engineering]. 2008 Sheng Wu Gong Cheng Xue Bao pmid:18616171
Liu SJ et al. Biosynthesis of poly (3-mercaptopropionate) and poly (3-mercaptopropionate-co-3-hydroxybutyrate) with recombinant Escherichia coli. 2003 Sheng Wu Gong Cheng Xue Bao pmid:15966321
Lü H et al. [Biocompatibility of surface modified PHBHHx with rat embryonic neural stem cells]. 2012 Sheng Wu Gong Cheng Xue Bao pmid:23311136
Qian ZW et al. [Dynamic variance of intracellular metabolic energies under rhythmical control for dissolved oxygen in PHB mixed cultivation]. 2001 Sheng Wu Gong Cheng Xue Bao pmid:11702705
Klein AH et al. Small-volume d-β-hydroxybutyrate solution infusion increases survivability of lethal hemorrhagic shock in rats. 2010 Shock pmid:20386494
Charles RA et al. Point-of-care blood ketone testing: screening for diabetic ketoacidosis at the emergency department. 2007 Singapore Med J pmid:17975686
Ji H et al. Details of thermal behavior of spin-coated film of biodegradable poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) copolymer studied by principal component analysis-based two-dimensional (PCA2D) correlation spectroscopy. 2009 Spectrochim Acta A Mol Biomol Spectrosc pmid:18718808
Ferrer-Lorente R et al. Effects of oral estrone on rat energy balance. 2005 Steroids pmid:15885727
Mirtsch S et al. Glycolytic changes after local hyperthermia in mouse liver and adenocarcinoma. 1990 Strahlenther Onkol pmid:2315847
Combs DJ et al. Glycolytic inhibition by 2-deoxyglucose reduces hyperglycemia-associated mortality and morbidity in the ischemic rat. 1986 Sep-Oct Stroke pmid:3764973
Lundy EF et al. Elevated blood ketone and glucagon levels cannot account for 1,3-butanediol induced cerebral protection in the Levine rat. 1987 Jan-Feb Stroke pmid:3810756
Rising CL and D'Alecy LG Hypoxia-induced increases in hypoxic tolerance augmented by beta-hydroxybutyrate in mice. 1989 Stroke pmid:2772983
Lundy EF et al. Butanediol induced cerebral protection from ischemic-hypoxia in the instrumented Levine rat. 1984 May-Jun Stroke pmid:6729886
Gueldry S et al. Beneficial effect of 1,3-butanediol on cerebral energy metabolism and edema following brain embolization in rats. 1990 Stroke pmid:2219211
Kirsch JR and D'Alecy LG Hypoxia induced preferential ketone utilization by rat brain slices. 1984 Mar-Apr Stroke pmid:6422588
Kirsch JR and D'Alecy LG Glucagon stimulates ketone utilization by rat brain slices. 1984 Mar-Apr Stroke pmid:6422589
Schreiber RA and Ungar AL Temporal changes in liver, blood, and brain glucose, glycogen, and beta-hydroxybutyrate after ethanol in C57BL/6J mice. 1984 Subst Alcohol Actions Misuse pmid:6533840
Hamanoue M et al. A correlation between arterial ketone body ratio and concentration of beta-hydroxybutyrate as an indicator of hepatic functional reserve. 1992 Surg. Today pmid:1392328
Mizobata Y et al. Oxidation of D(-)3-hydroxybutyrate administered to rats with extensive burns. 1996 Surg. Today pmid:8845609
Heindorff H et al. Hormonal and neural blockade prevents the postoperative increase in amino acid clearance and urea synthesis. 1992 Surgery pmid:1350868
Koustova E et al. Ketone and pyruvate Ringer's solutions decrease pulmonary apoptosis in a rat model of severe hemorrhagic shock and resuscitation. 2003 Surgery pmid:12947328
Rodriguez J et al. Carnitine metabolism during fasting in dogs. 1986 Surgery pmid:3520914
Hiraide A et al. Effect of 3-hydroxybutyrate on posttraumatic metabolism in man. 1991 Surgery pmid:1992551
Macián MC et al. Vibrio ponticus sp. nov., a neighbour of V fluvialis-V. furnissii clade, isolated from gilthead sea bream, mussels and seawater. 2004 Syst. Appl. Microbiol. pmid:15490554
Lam le H et al. Flow injection analysis of angiotensin I-converting enzyme inhibitory activity with enzymatic reactors. 2009 Talanta pmid:19615521
Shum L and Sadler TW Biochemical basis for D,L,-beta-hydroxybutyrate-induced teratogenesis. 1990 Teratology pmid:2278030
Hunter ES and Sadler TW D-(-)-beta-hydroxybutyrate-induced effects on mouse embryos in vitro. 1987 Teratology pmid:3424210
Moore DC et al. Morphological and physiological effects of beta-hydroxybutyrate on rat embryos grown in vitro at different stages. 1989 Teratology pmid:2595599
Styrud J and Eriksson UJ Development of rat embryos in culture media containing different concentrations of normal and diabetic rat serum. 1992 Teratology pmid:1462252
Zusman I et al. Effects of metabolic factors in the diabetic state on the in vitro development of preimplantation mouse embryos. 1987 Teratology pmid:3551178
Ornoy A et al. Role of reactive oxygen species (ROS) in the diabetes-induced anomalies in rat embryos in vitro: reduction in antioxidant enzymes and low-molecular-weight antioxidants (LMWA) may be the causative factor for increased anomalies. 1999 Teratology pmid:10590399
Shum L and Sadler TW Embryonic catch-up growth after exposure to the ketone body D,L,-beta-hydroxybutyrate in vitro. 1988 Teratology pmid:3238593
Horton WE et al. Effects of hyperketonemia on mouse embryonic and fetal glucose metabolism in vitro. 1985 Teratology pmid:3992491
Velazquez MA et al. The usefulness of a single measurement of insulin-like growth factor-1 as a predictor of embryo yield and pregnancy rates in a bovine MOET program. 2005 Theriogenology pmid:15936811
Reist M et al. First ovulation and ketone body status in the early postpartum period of dairy cows. 2000 Theriogenology pmid:11101031
Zerbe H et al. Altered functional and immunophenotypical properties of neutrophilic granulocytes in postpartum cows associated with fatty liver. 2000 Theriogenology pmid:11101037
Melendez P et al. Effect of ghrelin in dry matter intake and energy metabolism in prepartum sheep: a preliminary study. 2006 Theriogenology pmid:16797688
Rukkwamsuk T et al. Relationship between triacylglycerol concentration in the liver and first ovulation in postpartum dairy cows. 1999 Theriogenology pmid:10729031
Guedon L et al. Relationships between calf birth weight, prepartum concentrations of plasma energy metabolites and resumption of ovulation postpartum in Limousine suckled beef cows. 1999 Theriogenology pmid:10735119
Rizos D et al. The effect of feeding propylene glycol to dairy cows during the early postpartum period on follicular dynamics and on metabolic parameters related to fertility. 2008 Theriogenology pmid:18262261
Nieto CA et al. Ewe lambs with higher breeding values for growth achieve higher reproductive performance when mated at age 8 months. 2013 Theriogenology pmid:23764010