(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Sheep Diseases D012757 10 associated lipids
Stomach Diseases D013272 7 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Intestinal Diseases D007410 6 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Brain Neoplasms D001932 15 associated lipids
Hypothyroidism D007037 32 associated lipids
Uterine Diseases D014591 6 associated lipids
Weight Gain D015430 101 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Obesity D009765 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cholestasis D002779 23 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Hypoglycemia D007003 13 associated lipids
Metabolic Diseases D008659 12 associated lipids
Starvation D013217 47 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Hypocalcemia D006996 12 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Seifi HA et al. Metabolic predictors of post-partum disease and culling risk in dairy cattle. 2011 Vet. J. pmid:20457532
Stutchbury BJ et al. Effects of post-breeding moult and energetic condition on timing of songbird migration into the tropics. 2011 Proc. Biol. Sci. pmid:20659932
Velusamy T and Jain SK Effects of high glucose and ketosis (acetoacetate, ss-hydroxybutyrate) on PAI-1 secretion in human umbilical vascular endothelial cells. 2011 Clin. Appl. Thromb. Hemost. pmid:20530060
Ashby RD et al. Biopolymer scaffolds for use in delivering antimicrobial sophorolipids to the acne-causing bacterium Propionibacterium acnes. 2011 N Biotechnol pmid:20708720
Samala R et al. The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. 2011 Neurochem. Int. pmid:21070829
Lu J et al. Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. 2011 Clin. Chim. Acta pmid:21036159
Schutz PW et al. Effects of d-3-hydroxybutyrate treatment on hypoglycemic coma in rat pups. 2011 Exp. Neurol. pmid:21056562
Conway VD et al. Role of ribose deficit in rat testicular metabolism under conditions of overtraining. 2011 Bull. Exp. Biol. Med. pmid:22235407
Langley-Evans SC et al. Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: role of fetal exposure to {beta}-hydroxybutyrate. 2011 Exp. Physiol. pmid:20851857
Arora S et al. Diagnostic accuracy of point-of-care testing for diabetic ketoacidosis at emergency-department triage: {beta}-hydroxybutyrate versus the urine dipstick. 2011 Diabetes Care pmid:21307381
Iwata K et al. Central injection of ketone body suppresses luteinizing hormone release via the catecholaminergic pathway in female rats. 2011 J. Reprod. Dev. pmid:21358145
Asl AN et al. Prevalence of subclinical ketosis in dairy cattle in the Southwestern Iran and detection of cutoff point for NEFA and glucose concentrations for diagnosis of subclinical ketosis. 2011 Prev. Vet. Med. pmid:21439662
McArt JA et al. A field trial on the effect of propylene glycol on milk yield and resolution of ketosis in fresh cows diagnosed with subclinical ketosis. 2011 J. Dairy Sci. pmid:22118089
Schutz PW et al. Protective effects of d-3-hydroxybutyrate and propionate during hypoglycemic coma: clinical and biochemical insights from infant rats. 2011 Mol. Genet. Metab. pmid:21439874
Dasarathy S et al. Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis. 2011 Eur J Gastroenterol Hepatol pmid:21448070
Xiang Y and Shen J Simultaneous detection of cerebral metabolism of different substrates by in vivo ¹³C isotopomer MRS. 2011 J. Neurosci. Methods pmid:21419161
Sander AK et al. Ex vivo phagocytic overall performance of neutrophilic granulocytes and the relation to plasma insulin-like growth factor-I concentrations in dairy cows during the transition period. 2011 J. Dairy Sci. pmid:21426965
Huang HC et al. Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: a new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors. 2011 Biosens Bioelectron pmid:21398106
Budde CF et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains. 2011 Appl. Environ. Microbiol. pmid:21398488
Ding Y et al. Production of fumaric acid by Rhizopus oryzae: role of carbon-nitrogen ratio. 2011 Appl. Biochem. Biotechnol. pmid:21416336
Mulrooney TJ et al. Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma. 2011 PLoS ONE pmid:21479220
Dabos KJ et al. Regional variations in the concentrations of ketone bodies in cirrhosis and hepatic encephalopathy: a study in patients with TIPSS. 2011 Liver Int. pmid:21457443
Ruskin DN et al. A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease. 2011 Physiol. Behav. pmid:21501628
Eloqayli H et al. [2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells. 2011 Neurochem. Res. pmid:21538079
OuYang D et al. Metabolomic profiling of serum from human pancreatic cancer patients using 1H NMR spectroscopy and principal component analysis. 2011 Appl. Biochem. Biotechnol. pmid:21505807
Ugwu CU et al. Production of (R)-3-hydroxybutyric acid by fermentation and bioconversion processes with Azohydromonas lata. 2011 Bioresour. Technol. pmid:21507620
Sevastianova K et al. Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans. 2011 Am. J. Clin. Nutr. pmid:21525193
Waddell J et al. The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies. 2011 PLoS ONE pmid:21886776
Maurer GD et al. Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. 2011 BMC Cancer pmid:21791085
Dyck BL et al. Starch source and content in postpartum dairy cow diets: effects on plasma metabolites and reproductive processes. 2011 J. Dairy Sci. pmid:21854936
Cetin H et al. Polycythaemia in infants of diabetic mothers: β-hydroxybutyrate stimulates erythropoietic activity. 2011 J. Int. Med. Res. pmid:21819713
Mizutani T et al. Diagnosis of fulminant type 1 diabetes mellitus in an autopsy case with postmortem changes. 2011 Leg Med (Tokyo) pmid:21821459
Moriel P et al. Camelina meal and crude glycerin as feed supplements for developing replacement beef heifers. 2011 J. Anim. Sci. pmid:21821818
Jankovec Z et al. Influence of physical activity on metabolic state within a 3-h interruption of continuous subcutaneous insulin infusion in patients with type 1 diabetes. 2011 Diabetes Technol. Ther. pmid:21877927
Kılıçay E et al. Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy. 2011 Eur J Pharm Sci pmid:21884788
Wang Y et al. MicroRNAs in the regulation of interfacial behaviors of MSCs cultured on microgrooved surface pattern. 2011 Biomaterials pmid:21890196
González FD et al. Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. 2011 J. Vet. Sci. pmid:21897097
Marinou K et al. Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men. 2011 Br. J. Nutr. pmid:21251339
Lim S et al. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. 2011 PLoS ONE pmid:21931779
Zhang ZG et al. Serum antioxidant capacity of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21257536
Zhou C et al. How useful is basal renal tubular epithelial cell vacuolization as a marker for significant hyperglycemia at autopsy? 2011 J. Forensic Sci. pmid:21827461
Tyagi R et al. Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. 2011 J Appl Toxicol pmid:21218500
Stojanovic V and Ihle S Role of beta-hydroxybutyric acid in diabetic ketoacidosis: a review. 2011 Can. Vet. J. pmid:21731100
Bracken RM et al. Impact of pre-exercise rapid-acting insulin reductions on ketogenesis following running in Type 1 diabetes. 2011 Diabet. Med. pmid:21219433
Hu K et al. Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero (1)H-(13)C HSQC (HSQC(0)). 2011 J. Am. Chem. Soc. pmid:21247157
Arica V et al. Beta-ketothiolase deficiency brought with lethargy: case report. 2011 Hum Exp Toxicol pmid:21247997
Sznajder A and Jendrossek D Biochemical characterization of a new type of intracellular PHB depolymerase from Rhodospirillum rubrum with high hydrolytic activity on native PHB granules. 2011 Appl. Microbiol. Biotechnol. pmid:21274528
Rains JL and Jain SK Hyperketonemia decreases mitochondrial membrane potential and its normalization with chromium (III) supplementation in monocytes. 2011 Mol. Cell. Biochem. pmid:21153866
Tyzio R et al. Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate. 2011 J. Neurosci. pmid:21209187
Pifferi F et al. Mild experimental ketosis increases brain uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats. 2011 Nutr Neurosci pmid:21605500