| MeSH term | MeSH ID | Detail |
|---|---|---|
| Azotemia | D053099 | 1 associated lipids |
| Lethargy | D053609 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Disease Resistance | D060467 | 12 associated lipids |
| Fetal Alcohol Spectrum Disorders | D063647 | 6 associated lipids |
(r)-3-hydroxybutanoic acid
(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid
PubChem Associated disorders and diseases
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with (r)-3-hydroxybutanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Desrochers S et al. | Quantitation of 1,3-butanediol and its acidic metabolites by gas chromatography-mass spectrometry. | 1990 | Anal. Biochem. | pmid:2356962 |
| Tabata M and Totani M | A chemiluminescence-flow injection analysis of serum 3-hydroxybutyrate using a bioreactor consisting of 3-hydroxybutyrate dehydrogenase and NADH oxidase. | 1995 | Anal. Biochem. | pmid:8533882 |
| Takayama N et al. | Enzymatic fluorometric microplate assay for quantitative analysis of 3-hydroxybutyric acid in mouse plasma. | 2012 | Anal. Biochem. | pmid:22449496 |
| Des Rosiers C et al. | Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry. | 1988 | Anal. Biochem. | pmid:3189805 |
| Kientsch-Engel RI et al. | Measurement of ketone bodies in subcellular fractions using a spectrophotometric iron-chelate assay. | 1982 | Anal. Biochem. | pmid:7125202 |
| Cloarec O et al. | Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies. | 2005 | Anal. Chem. | pmid:15649048 |
| Huang ST et al. | Design and synthesis of a long-wavelength latent fluorogenic substrate for salicylate hydroxylase: a useful fluorimetric indicator for analyte determination by dehydrogenase-coupled biosensors. | 2010 | Anal. Chem. | pmid:20695438 |
| Jarute G et al. | On-line determination of the intracellular poly(beta-hydroxybutyric acid) content in transformed Escherichia coli and glucose during PHB production using stopped-flow attenuated total reflection FT-IR spectrometry. | 2004 | Anal. Chem. | pmid:15516127 |
| Smejkal P et al. | Separation of carboxylic acids in human serum by isotachophoresis using a commercial field-deployable analytical platform combined with in-house glass microfluidic chips. | 2012 | Anal. Chim. Acta | pmid:23146402 |
| Puchstein C et al. | [Pharmacokinetic studies of a new 20% fat emulsion containing 70% medium-chain triglycerides]. | 1990 | Anasth Intensivther Notfallmed | pmid:2309996 |
| Horton WE and Sadler TW | Mitochondrial alterations in embryos exposed to B-hydroxybutyrate in whole embryo culture. | 1985 | Anat. Rec. | pmid:4073566 |
| Yang L et al. | Anesthetic properties of the ketone bodies beta-hydroxybutyric acid and acetone. | 2007 | Anesth. Analg. | pmid:17717222 |
| Yang L and Sonner JM | The anesthetic-like effects of diverse compounds on wild-type and mutant gamma-aminobutyric acid type A and glycine receptors. | 2008 | Anesth. Analg. | pmid:18292428 |
| Kubli M et al. | An evaluation of isotonic "sport drinks" during labor. | 2002 | Anesth. Analg. | pmid:11812708 |
| Schricker T et al. | Influence of vaginal versus abdominal hysterectomy on perioperative glucose metabolism. | 1996 | Anesth. Analg. | pmid:8895274 |
| Clempson AM et al. | Associations between bovine IGFBP2 polymorphisms with fertility, milk production, and metabolic status in UK dairy cows. | 2012 | Anim. Biotechnol. | pmid:22537059 |
| Mann GE et al. | Metabolic variables and plasma leptin concentrations in dairy cows exhibiting reproductive cycle abnormalities identified through milk progesterone monitoring during the post partum period. | 2005 | Anim. Reprod. Sci. | pmid:16143211 |
| Leroy JL et al. | Metabolite and ionic composition of follicular fluid from different-sized follicles and their relationship to serum concentrations in dairy cows. | 2004 | Anim. Reprod. Sci. | pmid:15036497 |
| Opsomer G et al. | Insulin resistance: the link between metabolic disorders and cystic ovarian disease in high yielding dairy cows? | 1999 | Anim. Reprod. Sci. | pmid:10497917 |
| Jonsson NN et al. | Relationships among calving season, heat load, energy balance and postpartum ovulation of dairy cows in a subtropical environment. | 1997 | Anim. Reprod. Sci. | pmid:9360770 |
| Cavestany D et al. | Effect of prepartum diet on postpartum ovarian activity in Holstein cows in a pasture-based dairy system. | 2009 | Anim. Reprod. Sci. | pmid:18790580 |
| Senosy W et al. | Association between energy status early postpartum and subsequent embryonic mortality in high-yielding recipient cows. | 2012 | Anim. Sci. J. | pmid:22515687 |
| Morgante M et al. | Preliminary study on metabolic profile of pregnant and non-pregnant ewes with high or low degree of behavioral lateralization. | 2010 | Anim. Sci. J. | pmid:21108694 |
| Omazic AW et al. | High- and low-purity glycerine supplementation to dairy cows in early lactation: effects on silage intake, milk production and metabolism. | 2013 | Animal | pmid:23800400 |
| Jacobs AA et al. | Effects of short- and long-chain fatty acids on the expression of stearoyl-CoA desaturase and other lipogenic genes in bovine mammary epithelial cells. | 2013 | Animal | pmid:23597233 |
| Kafi M et al. | Relationships between thyroid hormones and serum energy metabolites with different patterns of postpartum luteal activity in high-producing dairy cows. | 2012 | Animal | pmid:23217229 |
| Smith SW et al. | Beta-hydroxybutyrate assay does not cross-react with gamma-hydroxybutyrate. | 2002 | Ann Emerg Med | pmid:12140509 |
| Jobard JM | [Alcoholic ketoacidosis. Apropos of a case with coma]. | 1993 | Ann Gastroenterol Hepatol (Paris) | pmid:8250517 |
| LEMOIGNE M et al. | [Assimilation of acetylacetic acid and beta-hydroxybutyric acid by B. megatherium]. | 1950 | Ann Inst Pasteur (Paris) | pmid:15425965 |
| Burrin JM et al. | Simple filter paper method for home monitoring of blood glucose, lactate, and 3-hydroxybutyrate. | 1981 | Ann. Clin. Biochem. | pmid:7283377 |
| Chammas NK et al. | Insulinoma: how reliable is the biochemical evidence? | 2003 | Ann. Clin. Biochem. | pmid:14629810 |
| Ruell PA and Gass GC | Enzymatic measurement of 3-hydroxybutyrate in extracts of blood without neutralization. | 1991 | Ann. Clin. Biochem. | pmid:1907121 |
| Carragher FM et al. | Pitfalls in the measurement of some intermediary metabolites. | 2003 | Ann. Clin. Biochem. | pmid:12880533 |
| al-Jubouri MA | Secondary adrenal failure in a young woman presenting as hypoglycaemic coma. | 1999 | Ann. Clin. Biochem. | pmid:10370775 |
| Geddes J et al. | Cardiac troponin I concentrations in people presenting with diabetic ketoacidosis. | 2007 | Ann. Clin. Biochem. | pmid:17594788 |
| Hooper RJ | Alcoholic ketoacidosis: the late presentation of acidosis in an alcoholic. | 1994 | Ann. Clin. Biochem. | pmid:7880081 |
| Prior TW et al. | Sensitivity of serum fructosamine in short term glycemic control. | 1989 Mar-Apr | Ann. Clin. Lab. Sci. | pmid:2751240 |
| Hu ZG et al. | Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats. | 2009 | Ann. Clin. Lab. Sci. | pmid:19201746 |
| Piliero PJ and Fish DG | Isoniazid-induced beta-hydroxybutyric acidosis. | 2001 | Ann. Intern. Med. | pmid:11329248 |
| Sutherland DE et al. | Hormonal and metabolic effects of a pancreatic endocrine graft. Vascularized segmental transplantation in insulin-dependent diabetic patients. | 1981 | Ann. Intern. Med. | pmid:6794405 |
| Sorisky A and Devlin JT | Intraoperative ketoacidosis and malnutrition. | 1988 | Ann. Intern. Med. | pmid:3293495 |
| Harik SI et al. | Ketogenic diet and the brain. | 1997 | Ann. N. Y. Acad. Sci. | pmid:9616776 |
| Kealey T et al. | Intermediary metabolism of the human hair follicle. | 1991 | Ann. N. Y. Acad. Sci. | pmid:1809089 |
| Cheng L et al. | Renal beta-hydroxybutyrate (beta OHB) transport in streptozotocin (Sz)-induced diabetic rats. | 1985 | Ann. N. Y. Acad. Sci. | pmid:3867311 |
| Balietti M et al. | A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes. | 2009 | Ann. N. Y. Acad. Sci. | pmid:19723079 |
| Santra S et al. | Ketogenic treatment reduces deleted mitochondrial DNAs in cultured human cells. | 2004 | Ann. Neurol. | pmid:15389892 |
| Knapp AC et al. | Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency. | 2008 | Ann. Nutr. Metab. | pmid:18417958 |
| Ladrière L and Malaisse WJ | Nutritional value of succinic acid monoethyl ester in starvation. | 1997 | Ann. Nutr. Metab. | pmid:9267586 |
| Firat A and Ozpinar A | Metabolic profile of pre-pregnancy, pregnancy and early lactation in multiple lambing Sakiz ewes. 1. Changes in plasma glucose, 3-hydroxybutyrate and cortisol levels. | 2002 | Ann. Nutr. Metab. | pmid:12011573 |
| Pinchasov Y and Elmaliah S | Broiler chick responses to anorectic agents: dietary acetic and propionic acids and the blood metabolites. | 1995 | Ann. Nutr. Metab. | pmid:7625770 |
| Connor H et al. | Comparison of the kinetics and utilisation of D(-)-and L(+)-sodium lactate in normal man. | 1983 | Ann. Nutr. Metab. | pmid:6651225 |
| Yamamoto K et al. | Increased secretion of triglyceride and cholesterol following inhibition of long-chain fatty acid oxidation in rat liver. | 1996 | Ann. Nutr. Metab. | pmid:8862698 |
| Ubukata E | Diurnal variation of blood ketone bodies in insulin-dependent diabetes mellitus and noninsulin-dependent diabetes mellitus patients: the relationship to serum C-peptide immunoreactivity and free insulin. | 1990 | Ann. Nutr. Metab. | pmid:2076025 |
| Barnouin J et al. | [Automated micro-determination of bovine plasma 3-hydroxybutyrate without deproteinization]. | 1986 | Ann. Rech. Vet. | pmid:3777808 |
| Coulon JB et al. | [Various blood parameters of energy metabolism in dairy cows at the start of lactation]. | 1985 | Ann. Rech. Vet. | pmid:4062195 |
| Doreau M et al. | [Variations in plasma components in lactating mares at late pregnancy-early lactation (author's transl)]. | 1981 | Ann. Rech. Vet. | pmid:7344559 |
| Fayet JC et al. | [Continuing eco-pathological survey: 6. Influence of zootechnical and space-time factors on some biochemical variables in the dairy cow]. | 1986 | Ann. Rech. Vet. | pmid:3800273 |
| Faye B et al. | [Continuing eco-pathological survey: 8. Epidemiological approach to postpartum mastitis in the dairy cow: discriminating biochemical parameters]. | 1986 | Ann. Rech. Vet. | pmid:3800276 |
| Doreau M et al. | [Effect of food intake on variations in different plasma constituents at the end of gestation and the start of lactation]. | 1983 | Ann. Rech. Vet. | pmid:6614783 |
| Bas P et al. | [Variations in the concentrations of certain blood constituents during the day and from day to day in alpine goats in mid lactation (author's transl)]. | 1980 | Ann. Rech. Vet. | pmid:7199887 |
| Hartl WH et al. | Minor role of ketone bodies in energy metabolism by skeletal muscle tissue during the postoperative course. | 1988 | Ann. Surg. | pmid:3276273 |
| Amark K et al. | Myocardial metabolism is better preserved after blood cardioplegia in infants. | 2006 | Ann. Thorac. Surg. | pmid:16798209 |
| Cahill GF | Fuel metabolism in starvation. | 2006 | Annu. Rev. Nutr. | pmid:16848698 |
| Tugnoli V et al. | Magnetic resonance spectroscopy and high performance liquid chromatography of neoplastic human renal tissues. | 2003 Mar-Apr | Anticancer Res. | pmid:12820421 |
| Wu Q et al. | Production of poly-3-hydroxybutyrate by Bacillus sp. JMa5 cultivated in molasses media. | 2001 | Antonie Van Leeuwenhoek | pmid:11759044 |
| Takanashi M et al. | Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1. | 2009 | Antonie Van Leeuwenhoek | pmid:19219638 |
| Laeger T et al. | Role of beta-hydroxybutyric acid in the central regulation of energy balance. | 2010 | Appetite | pmid:20416348 |
| Krueger T and Melendez P | Effect of ghrelin on feed intake and metabolites in lambs. | 2012 | Appetite | pmid:22280977 |
| Laessle RG et al. | Behavioral and biological correlates of dietary restraint in normal life. | 1989 | Appetite | pmid:2764557 |
| Alimova A et al. | Native fluorescence and excitation spectroscopic changes in Bacillus subtilis and Staphylococcus aureus bacteria subjected to conditions of starvation. | 2003 | Appl Opt | pmid:12868850 |
| Vogel C et al. | Thermal degradation of poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) in nitrogen and oxygen studied by thermogravimetric-Fourier transform infrared spectroscopy. | 2007 | Appl Spectrosc | pmid:17697470 |
| Anis SN et al. | Enhanced recovery and purification of P(3HB-co-3HHx) from recombinant Cupriavidus necator using alkaline digestion method. | 2012 | Appl. Biochem. Biotechnol. | pmid:22569781 |
| Park SJ and Lee SY | Biosynthesis of poly(3-hydroxybutyrate- co-3-hydroxyalkanoates) by metabolically engineered Escherichia coli strains. | 2004 | Appl. Biochem. Biotechnol. | pmid:15054261 |
| Gahlawat G and Srivastava AK | Estimation of fundamental kinetic parameters of polyhydroxybutyrate fermentation process of Azohydromonas australica using statistical approach of media optimization. | 2012 | Appl. Biochem. Biotechnol. | pmid:22915234 |
| Ding Y et al. | Production of fumaric acid by Rhizopus oryzae: role of carbon-nitrogen ratio. | 2011 | Appl. Biochem. Biotechnol. | pmid:21416336 |
| OuYang D et al. | Metabolomic profiling of serum from human pancreatic cancer patients using 1H NMR spectroscopy and principal component analysis. | 2011 | Appl. Biochem. Biotechnol. | pmid:21505807 |
| Xu J et al. | Metabolomic profilings of urine and serum from high fat-fed rats via 1H NMR spectroscopy and pattern recognition. | 2013 | Appl. Biochem. Biotechnol. | pmid:23306893 |
| Choi MH et al. | Production of poly(3-hydroxybutyric acid-co-4-hydroxybutyric acid) and poly(4-hydroxybutyric acid) without subsequent degradation by Hydrogenophaga pseudoflava. | 1999 | Appl. Environ. Microbiol. | pmid:10103252 |
| Uchino K et al. | Poly(3-hydroxybutyrate) (PHB) depolymerase PhaZa1 is involved in mobilization of accumulated PHB in Ralstonia eutropha H16. | 2008 | Appl. Environ. Microbiol. | pmid:18156336 |
| Hölscher T et al. | Production of the chiral compound (R)-3-hydroxybutyrate by a genetically engineered methylotrophic bacterium. | 2010 | Appl. Environ. Microbiol. | pmid:20581197 |
| Budde CF et al. | Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains. | 2011 | Appl. Environ. Microbiol. | pmid:21398488 |
| Kasuya K et al. | Biochemical and molecular characterization of the polyhydroxybutyrate depolymerase of Comamonas acidovorans YM1609, isolated from freshwater. | 1997 | Appl. Environ. Microbiol. | pmid:9406404 |
| Shozui F et al. | Engineering of polyhydroxyalkanoate synthase by Ser477X/Gln481X saturation mutagenesis for efficient production of 3-hydroxybutyrate-based copolyesters. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19506863 |
| Lee SH et al. | Biosynthesis of enantiopure (S)-3-hydroxybutyric acid in metabolically engineered Escherichia coli. | 2008 | Appl. Microbiol. Biotechnol. | pmid:18461320 |
| Jossek R et al. | In vitro biosynthesis of poly(3-hydroxybutyric acid) by using purified poly(hydroxyalkanoic acid) synthase of Chromatium vinosum. | 1998 | Appl. Microbiol. Biotechnol. | pmid:9581289 |
| Bayer M et al. | Purification and characterization of an (S)-3-hydroxycarboxylate oxidoreductase from Clostridium tyrobutyricum. | 1994 | Appl. Microbiol. Biotechnol. | pmid:7765819 |
| Matsumoto K et al. | Efficient (R)-3-hydroxybutyrate production using acetyl CoA-regenerating pathway catalyzed by coenzyme A transferase. | 2013 | Appl. Microbiol. Biotechnol. | pmid:22592551 |
| De Schryver P et al. | Poly-beta-hydroxybutyrate (PHB) increases growth performance and intestinal bacterial range-weighted richness in juvenile European sea bass, Dicentrarchus labrax. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20094715 |
| Kawata Y et al. | Efficient secreted production of (R)-3-hydroxybutyric acid from living Halomonas sp. KM-1 under successive aerobic and microaerobic conditions. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22718250 |
| Tanaka K et al. | Cell growth and P(3HB) accumulation from CO2 of a carbon monoxide-tolerant hydrogen-oxidizing bacterium, Ideonella sp. O-1. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21695533 |
| GarcÃa-Hidalgo J et al. | Extracellular production of Streptomyces exfoliatus poly(3-hydroxybutyrate) depolymerase in Rhodococcus sp. T104: determination of optimal biocatalyst conditions. | 2012 | Appl. Microbiol. Biotechnol. | pmid:21845385 |
| Qiu YZ et al. | Metabolic engineering of Aeromonas hydrophila for the enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). | 2006 | Appl. Microbiol. Biotechnol. | pmid:15983806 |
| Sznajder A and Jendrossek D | Biochemical characterization of a new type of intracellular PHB depolymerase from Rhodospirillum rubrum with high hydrolytic activity on native PHB granules. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21274528 |
| Liu Q et al. | Microbial production of R-3-hydroxybutyric acid by recombinant E. coli harboring genes of phbA, phbB, and tesB. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17609944 |
| Tygesen MP et al. | Late gestational nutrient restriction: effects on ewes' metabolic and homeorhetic adaptation, consequences for lamb birth weight and lactation performance. | 2008 | Arch Anim Nutr | pmid:18341079 |
| VIALE L et al. | [Ketolytic fate of beta-hydroxibutyric acid: Note IV--Ketolysis of beta-hydroxybutyric acid in liver disease]. | 1950 Jan-Feb | Arch Maragliano Patol Clin | pmid:15419991 |
| MORGANO G | [Correlations between uric acid metabolism and ketone bodies metabolism. IV. Behavior of uricemia and uricosuria after administration of beta-hydroxybutyric acid in patients with liver disease]. | 1950 Mar-Apr | Arch Maragliano Patol Clin | pmid:15433760 |
| Buszewicz G et al. | [Diagnostic usefulness of the beta-hydroxybutyrate/acetone ratio in medico-legal diagnostics of sudden deaths]. | 2007 Jul-Sep | Arch Med Sadowej Kryminol | pmid:17907621 |
| Ozawa K et al. | Metabolic abnormalities associated with postoperative organ failure. A redox theory. | 1983 | Arch Surg | pmid:6639332 |
| Desai SP et al. | Branched-chain amino acid administration in surgical patients. Effects on amino acid and fuel substrate profiles. | 1987 | Arch Surg | pmid:3592966 |