(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Encephalopathy, Bovine Spongiform D016643 2 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Liver Failure D017093 5 associated lipids
Hyperandrogenism D017588 5 associated lipids
Glucose Intolerance D018149 13 associated lipids
Adenocarcinoma, Clear Cell D018262 1 associated lipids
Placenta, Retained D018457 3 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Authors Title Published Journal PubMed Link
Dunger DB et al. Impact of increased growth hormone secretion on carbohydrate metabolism in adolescents with diabetes. 1991 Acta Paediatr Scand Suppl pmid:1723835
Lean IJ et al. Postparturient metabolic and production responses in cows previously exposed to long-term treatment with somatotropin. 1991 J. Dairy Sci. pmid:1744273
Zuniga-Guarjardo S et al. Insulin resistance and action in hypertriglyceridemia. 1991 Diabetes Res. Clin. Pract. pmid:1748063
Arakawa T et al. Effect of ketone body (D-3-hydroxybutyrate) on neural activity and energy metabolism in hippocampal slices of the adult guinea pig. 1991 Neurosci. Lett. pmid:1749516
Watanabe T et al. Serum ketone response to glucagon as a marker of insulin dependency in diabetics. 1991 Diabetes Res. Clin. Pract. pmid:1756681
Miller PS et al. Patterns of nutrient uptake by the mammary glands of lactating dairy cows. 1991 J. Dairy Sci. pmid:1757621
Miller PS et al. Relationship of early lactation and bovine somatotropin on nutrient uptake by cow mammary glands. 1991 J. Dairy Sci. pmid:1757622
Vicario C et al. The fate of lactate in isolated cells from early neonatal rat brain. Comparison with glucose and 3-hydroxybutyrate. 1991 Biochem. Soc. Trans. pmid:1889539
Gagliostro G et al. Duodenal rapeseed oil infusion in early and midlactation cows. 3. Plasma hormones and mammary apparent uptake of metabolites. 1991 J. Dairy Sci. pmid:1894799
Tokuyama K et al. Seasonal glucose uptake in marmots (Marmota flaviventris): the role of pancreatic hormones. 1991 Comp Biochem Physiol A Comp Physiol pmid:1685387
Kimura RE and Ilich JZ The oxidation of 3-hydroxybutyrate in developing rat jejunum. 1991 J. Pediatr. Gastroenterol. Nutr. pmid:1685747
Thorell JO et al. Synthesis of [1-11C]-beta-hydroxybutyric acid. 1991 Acta Radiol Suppl pmid:1666800
Patel HR et al. A quantitative histochemical study of D-amino acid oxidase activity in rat liver in relationship with feeding conditions. 1991 J. Histochem. Cytochem. pmid:1670580
Hjortdal VE et al. Fuel metabolism in a pig myocutaneous island flap model. 1991 Plast. Reconstr. Surg. pmid:1896538
Marker JC et al. Catecholamines in prevention of hypoglycemia during exercise in humans. 1991 Am. J. Physiol. pmid:1674642
Schroeder H et al. Influence of early chronic phenobarbital treatment on cerebral arteriovenous differences of glucose and ketone bodies in the developing rat. 1991 Int. J. Dev. Neurosci. pmid:1781304
Hiraide A et al. Effect of sodium D-3-hydroxybutyrate on amino acidemia in hemorrhagic hypotension. 1991 Eur Surg Res pmid:1782970
Wetzel DM and Salpeter MM Fibrillation and accelerated AChR degradation in long-term muscle organ culture. 1991 Muscle Nerve pmid:1944400
Hawkins RA and Mans AM Regional blood-brain barrier transport of ketone bodies in portacaval-shunted rats. 1991 Am. J. Physiol. pmid:1951691
Grootveld M et al. Influence of an intravenous dose of aurothiomalate on the status of low-molecular-mass endogenous metabolites in blood plasma: a proton nuclear magnetic resonance (NMR) study. 1991 Agents Actions Suppl. pmid:1906237
Hagström-Toft E et al. Effects of insulin deprivation and replacement on in vivo subcutaneous adipose tissue substrate metabolism in humans. 1991 Diabetes pmid:2040382
Ruell PA and Gass GC Enzymatic measurement of 3-hydroxybutyrate in extracts of blood without neutralization. 1991 Ann. Clin. Biochem. pmid:1907121
Boden G and Jadali F Effects of lipid on basal carbohydrate metabolism in normal men. 1991 Diabetes pmid:2040385
Lynch GP et al. Nitrogen metabolism of lactating ewes fed rumen-protected methionine and lysine. 1991 J. Dairy Sci. pmid:1910058
Bahnson BJ and Anderson VE Crotonase-catalyzed beta-elimination is concerted: a double isotope effect study. 1991 Biochemistry pmid:2043630
Orskov L et al. Decreased hepatic glucagon responses in type 1 (insulin-dependent) diabetes mellitus. 1991 Diabetologia pmid:1916058
Larsen S et al. The effect of insulin withdrawal on intermediary metabolism in patients with diabetes secondary to chronic pancreatitis. 1991 Acta Endocrinol. pmid:2028708
Quigley JD et al. Changes in blood glucose, nonesterified fatty acids, and ketones in response to weaning and feed intake in young calves. 1991 J. Dairy Sci. pmid:2030170
Hirsch IB et al. Insulin and glucagon in prevention of hypoglycemia during exercise in humans. 1991 Am. J. Physiol. pmid:2035626
Weinstein I et al. Secretion of triglyceride and ketogenesis by livers from spontaneous diabetic BB Wistar rats. 1991 Biochem. Biophys. Res. Commun. pmid:2039501
Harrison MP et al. beta-Hydroxybutyrate: a urinary marker of imipenem induced nephrotoxicity in the cynomolgus monkey detected by high field 1H NMR spectroscopy. 1991 Biochem. Pharmacol. pmid:2039554
Griffin H et al. Changes in plasma lipoprotein metabolism in chicks in response to polychlorinated biphenyls (PCBs). 1991 Biochem. Pharmacol. pmid:1930274
Svedjeholm R et al. Myocardial uptake of amino acids and other substrates in relation to myocardial oxygen consumption four hours after cardiac operations. 1991 J. Thorac. Cardiovasc. Surg. pmid:2008107
Davis TA et al. Response of muscle protein synthesis to fasting in suckling and weaned rats. 1991 Am. J. Physiol. pmid:1721504
Cisse M et al. Slow release somatotropin in dairy heifers and cows fed two levels of energy concentrate. 2. Plasma hormones and metabolites. 1991 J. Dairy Sci. pmid:1860980
Ratheiser K et al. Inhibition by etomoxir of carnitine palmitoyltransferase I reduces hepatic glucose production and plasma lipids in non-insulin-dependent diabetes mellitus. 1991 Metab. Clin. Exp. pmid:1943747
Lautenbacher S et al. Dieting and pain sensitivity: a validation of clinical findings. 1991 Physiol. Behav. pmid:1801020
Harding JE and Evans PC beta-Hydroxybutyrate is an alternative substrate for the fetal sheep brain. 1991 J. Dev. Physiol. pmid:1823915
Bleiberg B et al. Determination of plasma lactic acid concentration and specific activity using high-performance liquid chromatography. 1991 J. Chromatogr. pmid:1783635
Rizzo T et al. Correlations between antepartum maternal metabolism and child intelligence. 1991 N. Engl. J. Med. pmid:1881416
Ramirez R et al. Assay of 3-hydroxybutyrate in the picomolar range. 1991 Biochem. Med. Metab. Biol. pmid:1883629
Ruwe PJ et al. Effect of maternal fasting on fetal and placental lipid metabolism in swine. 1991 J. Anim. Sci. pmid:2066303
Philpott MP and Kealey T Metabolic studies on isolated hair follicles: hair follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle. 1991 J. Invest. Dermatol. pmid:2045676
Gilbert M et al. Role of free fatty acids in hepatic insulin resistance during late pregnancy in conscious rabbits. 1991 Am. J. Physiol. pmid:2058668
Kim DK et al. Effects of beta-hydroxybutyrate on oxidative metabolism and phosphorylation potential in canine heart in vivo. 1991 Am. J. Physiol. pmid:2058715
Veenhuizen JJ et al. Metabolic changes in blood and liver during development and early treatment of experimental fatty liver and ketosis in cows. 1991 J. Dairy Sci. pmid:1787194
Persson M et al. Measurement of plasma acetate kinetics using high-performance liquid chromatography. 1991 Anal. Biochem. pmid:1789417
Kang S et al. Absorption kinetics and action profiles of subcutaneously administered insulin analogues (AspB9GluB27, AspB10, AspB28) in healthy subjects. 1991 Diabetes Care pmid:1797487
Kripke SA et al. Experimental short-bowel syndrome: effect of an elemental diet supplemented with short-chain triglycerides. 1991 Am. J. Clin. Nutr. pmid:1706907
McBride MO et al. Bedside blood ketone body monitoring. 1991 Aug-Sep Diabet. Med. pmid:1833124
Simkhovich BZ et al. [The effect of mildronate on carnitine-dependent and carnitine-independent ketogenesis in rats]. 1991 Jul-Aug Farmakol Toksikol pmid:1786824
Shutenko ZhV et al. [Potentiation of the antiketogenic effect of exogenous glucose with the help of the new beta-oxidation inhibitor mildronate--3-(2,2,2-trimethylhydrazine)propionate]. 1991 Mar-Apr Vopr. Med. Khim. pmid:1897198
MacFie J et al. Continuous versus intermittent infusion of fat emulsions during total parenteral nutrition: clinical trial. 1991 Mar-Apr Nutrition pmid:1802203
Lilet H et al. [Lack of benefit from the intermittent administration of insulin in treatment using subcutaneous perfusion pump in type 1 diabetes]. 1991 May-Jun Diabete Metab pmid:1884881
Pal BR et al. Contrasting metabolic effects of continuous and pulsatile growth hormone administration in young adults with type 1 (insulin-dependent) diabetes mellitus. 1992 Diabetologia pmid:1612227
Bostwick JR et al. Phosphoethanolamine enhances high-affinity choline uptake and acetylcholine synthesis in dissociated cell cultures of the rat septal nucleus. 1992 J. Neurochem. pmid:1613501
Vicario C and Medina JM Metabolism of lactate in the rat brain during the early neonatal period. 1992 J. Neurochem. pmid:1613508
Pere MC et al. Hepatic metabolism during fasting-refeeding transition in conscious pregnant rabbits. 1992 Am. J. Physiol. pmid:1616023
Arnould T et al. Effect of hypoxia upon intracellular calcium concentration of human endothelial cells. 1992 J. Cell. Physiol. pmid:1618920
Metcalfe HK et al. Effects of D-3-hydroxybutyrate and acetoacetate on lactate removal in isolated perfused livers from starved and fed rats. 1992 Metab. Clin. Exp. pmid:1556952
Hunsicker KD et al. Effect of starvation or restriction on self-selection of macronutrients in rats. 1992 Physiol. Behav. pmid:1557442
Langhans W et al. [Effect of carbohydrate intake during a long distance run on work capacity and metabolism]. 1992 Z Ernahrungswiss pmid:1585683
Marker JC et al. Attenuated glucose recovery from hypoglycemia in the elderly. 1992 Diabetes pmid:1587394
Farrer M et al. Effect of acute inhibition of lipolysis on operation of the glucose-fatty acid cycle in hepatic cirrhosis. 1992 Metab. Clin. Exp. pmid:1588824
Ferrier B et al. Transport of beta-hydroxybutyrate and acetoacetate along rat nephrons: a micropuncture study. 1992 Am. J. Physiol. pmid:1590421
Schlichtig R et al. Hepatic dysoxia commences during O2 supply dependence. 1992 J. Appl. Physiol. pmid:1592742
Gratama JW et al. Myocardial carbohydrate, ketone, and fatty acid uptake in conscious lambs with aortopulmonary shunts. 1992 Pediatr. Res. pmid:1635842
Yokoyama H et al. Transient extreme insulin resistance in shock during diabetic ketoacidosis. 1992 Endocrinol. Jpn. pmid:1294375
Zaidi SS and Bhatnagar VK Spectral evidence for the oxidation of beta-hydroxybutyrate to acetoacetate: diminution of spectra by glucose and chloride. 1992 Indian J. Biochem. Biophys. pmid:1294466
Windisch W and Kirchgessner M [Concentrations of metabolites and hormones in the blood plasma of lactating dairy cows during treatment with recombinant bovine somatotropin (BST)]. 1992 Arch Tierernahr pmid:1296558
Yang N and Jiang Z [The kinetic observation of serum ketone body levels in surgical patients receiving MCT or LCT emulsions]. 1992 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:1303814
Ikeda T et al. Adrenergic mechanism in hyperketonemia in thyrotoxic and starved rats. 1992 Exp. Clin. Endocrinol. pmid:1305070
Johnson AB et al. Effect of increased free fatty acid supply on glucose metabolism and skeletal muscle glycogen synthase activity in normal man. 1992 Clin. Sci. pmid:1311661
Santini FJ et al. Dietary fiber and milk yield, mastication, digestion, and the rate of passage in goats fed alfalfa hay. 1992 J. Dairy Sci. pmid:1311727
Beaufrère B et al. Effects of D-beta-hydroxybutyrate and long- and medium-chain triglycerides on leucine metabolism in humans. 1992 Am. J. Physiol. pmid:1312786
Kennedy CH et al. tert-Butyl hydroperoxide-induced radical production in rat liver mitochondria. 1992 Free Radic. Biol. Med. pmid:1317326
Fulcher GR et al. Acute metabolic and hormonal responses to the inhibition of lipolysis in non-obese patients with non-insulin-dependent (type 2) diabetes mellitus: effects of acipimox. 1992 Clin. Sci. pmid:1317767
Sato N et al. Mechanism of inhibitory action of ketone bodies on the production of reactive oxygen intermediates (ROIS) by polymorphonuclear leukocytes. 1992 Life Sci. pmid:1319534
Turcotte LP et al. Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans. 1992 Am. J. Physiol. pmid:1319676
deRoos R and deRoos CC Effects of mammalian ACTH on potential fuels and gluconeogenic substrates in the plasma of the spiny dogfish shark (Squalus acanthias). 1992 Gen. Comp. Endocrinol. pmid:1320581
Riegel W and Hörl WH Ketone body-induced dissociation between hepatocyte gluconeogenesis and ureagenesis in acutely uremic rats. 1992 Miner Electrolyte Metab pmid:1465055
Inokuchi T et al. Resistance to ketosis in moderately obese patients: influence of fatty liver. 1992 Intern. Med. pmid:1477471
Alonso de la Torre SR et al. Carrier-mediated beta-D-hydroxybutyrate transport in brush-border membrane vesicles from rat placenta. 1992 Pediatr. Res. pmid:1408469
Knights KM and Drew R The effects of ibuprofen enantiomers on hepatocyte intermediary metabolism and mitochondrial respiration. 1992 Biochem. Pharmacol. pmid:1417953
Linares A et al. Comparative effect of fasting on acetoacetate and D-3-hydroxybutyrate metabolism in the newborn chick. 1992 Biochem. Int. pmid:1482404
Drackley JK et al. Metabolic changes in dairy cows with ketonemia in response to feed restriction and dietary 1,3-butanediol. 1992 J. Dairy Sci. pmid:1500562
Lean IJ et al. Time series cross-correlation analysis of postparturient relationships among serum metabolites and yield variables in Holstein cows. 1992 J. Dairy Sci. pmid:1500586
Bertics SJ et al. Effect of prepartum dry matter intake on liver triglyceride concentration and early lactation. 1992 J. Dairy Sci. pmid:1500587
McCarthy JP et al. Changes in the plasma concentration of gastric inhibitory polypeptide and other metabolites in response to feeding in sheep. 1992 J. Endocrinol. pmid:1402533
Luzi L et al. Lack of feedback inhibition of insulin secretion in denervated human pancreas. 1992 Diabetes pmid:1359986
Fulcher GR et al. Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects. 1992 Diabetes pmid:1397716
Broussolle C et al. Effects of different lipid substrates on glucose metabolism in normal postabsorptive humans. 1992 Metab. Clin. Exp. pmid:1461133
Goldstein RE et al. The effects of acute elevations in plasma cortisol levels on alanine metabolism in the conscious dog. 1992 Metab. Clin. Exp. pmid:1461135
Styrud J and Eriksson UJ Development of rat embryos in culture media containing different concentrations of normal and diabetic rat serum. 1992 Teratology pmid:1462252
McGarry JD What if Minkowski had been ageusic? An alternative angle on diabetes. 1992 Science pmid:1439783
Bijlsma JG and Counotte GH [The effect of feeding mangel-wurzels on blood beta-hydroxybutyrate level of milk-producing cows]. 1992 Tijdschr Diergeneeskd pmid:1440545
Leonard F et al. Possible effect of pH on the survival of leptospires in cattle urine. 1992 Vet. Rec. pmid:1441163
Zimmerman CA et al. Influence of dietary protein and supplemental niacin on lactational performance of cows fed normal and low fiber diets. 1992 J. Dairy Sci. pmid:1323586
Kruszynska YT et al. Twenty-four hour C-peptide and insulin secretion rates and diurnal profiles of glucose, lipids and intermediary metabolites in cirrhosis. 1992 Clin. Sci. pmid:1335398
Erickson PS et al. Supplementation of dairy cow diets with calcium salts of long-chain fatty acids and nicotinic acid in early lactation. 1992 J. Dairy Sci. pmid:1315811