(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Encephalopathy, Bovine Spongiform D016643 2 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Liver Failure D017093 5 associated lipids
Hyperandrogenism D017588 5 associated lipids
Glucose Intolerance D018149 13 associated lipids
Adenocarcinoma, Clear Cell D018262 1 associated lipids
Placenta, Retained D018457 3 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Alvarez-Rodríguez J et al. Metabolic and luteal function in winter-calving Spanish beef cows as affected by calf management and breed. 2010 J Anim Physiol Anim Nutr (Berl) pmid:19663981
Cheng B et al. D-beta-hydroxybutyrate prevents MPP+-induced neurotoxicity in PC12 cells. 2010 Neurochem. Res. pmid:19851865
Silva-del-Río N et al. Effects of twin pregnancy and dry period feeding strategy on milk production, energy balance, and metabolic profiles in dairy cows. 2010 J. Anim. Sci. pmid:19854992
Holmgren CD et al. Energy substrate availability as a determinant of neuronal resting potential, GABA signaling and spontaneous network activity in the neonatal cortex in vitro. 2010 J. Neurochem. pmid:19943846
Butchbach ME et al. Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. 2010 Biochem. Biophys. Res. Commun. pmid:19945425
Elliott S et al. The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosis. 2010 Forensic Sci. Int. pmid:19954904
Wood CM et al. The influence of feeding and fasting on plasma metabolites in the dogfish shark (Squalus acanthias). 2010 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:19782147
Hartman AL et al. Seizure tests distinguish intermittent fasting from the ketogenic diet. 2010 Epilepsia pmid:20477852
Quiroz-Rocha GF et al. Short communication: Effect of sampling time relative to the first daily feeding on interpretation of serum fatty acid and beta-hydroxybutyrate concentrations in dairy cattle. 2010 J. Dairy Sci. pmid:20412917
Zhang YQ et al. Effect of a mixture of steam-flaked corn and soybeans on health, growth, and selected blood metabolism of Holstein calves. 2010 J. Dairy Sci. pmid:20412943
Laeger T et al. Role of beta-hydroxybutyric acid in the central regulation of energy balance. 2010 Appetite pmid:20416348
Voyvoda H and Erdogan H Use of a hand-held meter for detecting subclinical ketosis in dairy cows. 2010 Res. Vet. Sci. pmid:20471047
Forslund KB et al. Low cortisol levels in blood from dairy cows with ketosis: a field study. 2010 Acta Vet. Scand. pmid:20487518
Gasior M et al. Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. 2010 Epilepsia pmid:20491877
Osman MA et al. Chronic metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or both. 2010 J. Dairy Sci. pmid:20655418
Ospina PA et al. Association between the proportion of sampled transition cows with increased nonesterified fatty acids and beta-hydroxybutyrate and disease incidence, pregnancy rate, and milk production at the herd level. 2010 J. Dairy Sci. pmid:20655428
Zhou J et al. The use of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds for tarsal repair in eyelid reconstruction in the rat. 2010 Biomaterials pmid:20663550
Jeong HJ et al. The ketogenic diet suppresses the cathepsin E expression induced by kainic acid in the rat brain. 2010 Yonsei Med. J. pmid:20635438
Yamada T et al. {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20516259
Becskei C et al. Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20538900
Veldhorst MA et al. Presence or absence of carbohydrates and the proportion of fat in a high-protein diet affect appetite suppression but not energy expenditure in normal-weight human subjects fed in energy balance. 2010 Br. J. Nutr. pmid:20565999
Kashiwaya Y et al. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. 2010 J. Biol. Chem. pmid:20529850
Thaler S et al. Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat--possible involvement of kynurenic acid. 2010 Graefes Arch. Clin. Exp. Ophthalmol. pmid:20532550
Seong SH et al. L-carnitine-supplemented parenteral nutrition improves fat metabolism but fails to support compensatory growth in premature Korean infants. 2010 Nutr Res pmid:20534325
Zhang C et al. Folate-mediated poly(3-hydroxybutyrate-co-3-hydroxyoctanoate) nanoparticles for targeting drug delivery. 2010 Eur J Pharm Biopharm pmid:20472060
Kelly AK et al. Repeatability of feed efficiency, carcass ultrasound, feeding behavior, and blood metabolic variables in finishing heifers divergently selected for residual feed intake. 2010 J. Anim. Sci. pmid:20525931
Zeugswetter F et al. Efficacy of plasma beta-hydroxybutyrate concentration as a marker for diabetes mellitus in acutely sick cats. 2010 J. Feline Med. Surg. pmid:20117951
Fisher AD et al. The effects of 12, 30, or 48 hours of road transport on the physiological and behavioral responses of sheep. 2010 J. Anim. Sci. pmid:20154169
Samoilova M et al. Chronic in vitro ketosis is neuroprotective but not anti-convulsant. 2010 J. Neurochem. pmid:20163521
Shozui F et al. A new beneficial mutation in pseudomonas sp. 61-3 polyhydroxyalkanoate (PHA) synthase for enhanced cellular content of 3-hydroxybutyrate-based PHA explored using its enzyme homolog as a mutation template. 2010 Biosci. Biotechnol. Biochem. pmid:20699564
Ide T Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. 2010 Biosci. Biotechnol. Biochem. pmid:20699574
Hässig M et al. [Benefit of clinical and laboratory parameters for the diagnosis of endometritis in dairy cows]. 2010 Schweiz. Arch. Tierheilkd. pmid:20814859
Bonuccelli G et al. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. 2010 Cell Cycle pmid:20818174
Eslamizad M et al. Effects of 6 times daily milking during early versus full lactation of Holstein cows on milk production and blood metabolites. 2010 J. Dairy Sci. pmid:20723679
Fürll M et al. Effect of multiple intravenous injections of butaphosphan and cyanocobalamin on the metabolism of periparturient dairy cows. 2010 J. Dairy Sci. pmid:20723690
Oliveira RA et al. Effects of feeding polyphenols from pomegranate extract on health, growth, nutrient digestion, and immunocompetence of calves. 2010 J. Dairy Sci. pmid:20723701
Meier S et al. Effects of divergent Holstein-Friesian strain and diet on diurnal patterns of plasma metabolites and hormones. 2010 J. Dairy Res. pmid:20822560
Zhang XX and Rainey PB Bet hedging in the underworld. 2010 Genome Biol. pmid:21062509
Soberon F et al. Effects of increased milking frequency on metabolism and mammary cell proliferation in Holstein dairy cows. 2010 J. Dairy Sci. pmid:20105528
Henderson DW and Schlesinger DP Use of a point-of-care beta-hydroxybutyrate sensor for detection of ketonemia in dogs. 2010 Can. Vet. J. pmid:21119867
Karcagi RG et al. Milk production, peripartal liver triglyceride concentration and plasma metabolites of dairy cows fed diets supplemented with calcium soaps or hydrogenated triglycerides of palm oil. 2010 J. Dairy Res. pmid:20030903
Kirmse K et al. GABA depolarizes immature neocortical neurons in the presence of the ketone body ß-hydroxybutyrate. 2010 J. Neurosci. pmid:21106838
Atshaves BP et al. High dietary fat exacerbates weight gain and obesity in female liver fatty acid binding protein gene-ablated mice. 2010 Lipids pmid:20035485
Stasiak P et al. In vivo assessment of parenteral formulations of oligo(3-hydroxybutyric Acid) conjugates with the model compound Ibuprofen. 2010 AAPS PharmSciTech pmid:21088943
Jaakson H et al. Field trial on glucose-induced insulin and metabolite responses in Estonian Holstein and Estonian Red dairy cows in two herds. 2010 Acta Vet. Scand. pmid:20089161
Tetrick MA et al. Blood D-(-)-3-hydroxybutyrate concentrations after oral administration of trioctanoin, trinonanoin, or tridecanoin to newborn rhesus monkeys (Macaca mulatta). 2010 Comp. Med. pmid:21262136
Rivera N et al. Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs. 2010 J. Clin. Invest. pmid:21084754
Wagner SA and Schimek DE Evaluation of the effect of bolus administration of 50% dextrose solution on measures of electrolyte and energy balance in postpartum dairy cows. 2010 Am. J. Vet. Res. pmid:20807148
Kalaitzakis E et al. Clinicopathological evaluation of downer dairy cows with fatty liver. 2010 Can. Vet. J. pmid:20808573
Morgante M et al. Preliminary study on metabolic profile of pregnant and non-pregnant ewes with high or low degree of behavioral lateralization. 2010 Anim. Sci. J. pmid:21108694