(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Insulin Resistance D007333 99 associated lipids
Weight Gain D015430 101 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Brunner MP et al. Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization. 2011 Circ Cardiovasc Genet pmid:22010138
Moazzami AA et al. Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients. 2011 J. Nutr. pmid:22013201
Chapinal N et al. The association of serum metabolites with clinical disease during the transition period. 2011 J. Dairy Sci. pmid:21943741
Kreipe L et al. First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in nonketotic early lactating cows. 2011 J. Dairy Sci. pmid:21943742
Bernier-Dodier P et al. Effect of dry period management on mammary gland function and its endocrine regulation in dairy cows. 2011 J. Dairy Sci. pmid:21943744
Morey SD et al. Effects of encapsulated niacin on metabolism and production of periparturient dairy cows. 2011 J. Dairy Sci. pmid:21943760
Yu HY et al. Clinical utility of Abbott Precision Xceed Pro® ketone meter in diabetic patients. 2011 Pediatr Diabetes pmid:22034832
Arora S et al. Point-of-care beta-hydroxybutyrate testing for assessing diabetic ketoacidosis severity prior to treatment in the emergency department. 2011 Diabetes Res. Clin. Pract. pmid:21955959
Ivarsson N et al. AICAR reverses ketone body mediated insulin resistance in isolated oxidative muscle. 2011 Biochem. Biophys. Res. Commun. pmid:21982775
Stutchbury BJ et al. Effects of post-breeding moult and energetic condition on timing of songbird migration into the tropics. 2011 Proc. Biol. Sci. pmid:20659932
Ashby RD et al. Biopolymer scaffolds for use in delivering antimicrobial sophorolipids to the acne-causing bacterium Propionibacterium acnes. 2011 N Biotechnol pmid:20708720
Otis JP et al. Cholesterol and lipoprotein dynamics in a hibernating mammal. 2011 PLoS ONE pmid:22195001
Conway VD et al. Role of ribose deficit in rat testicular metabolism under conditions of overtraining. 2011 Bull. Exp. Biol. Med. pmid:22235407
Numis AL et al. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. 2011 Epilepsy Res. pmid:21700429
Liu F et al. Metabolic engineering of Aeromonas hydrophila 4AK4 for production of copolymers of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoate. 2011 Bioresour. Technol. pmid:21680176
Li XB et al. Renal function of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21672951
Deng-Bryant Y et al. Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. 2011 J. Neurotrauma pmid:21635175
Ruprechter G et al. Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes. 2011 Acta Vet. Scand. pmid:21635772
Harris DL et al. Cot-side electroencephalography monitoring is not clinically useful in the detection of mild neonatal hypoglycemia. 2011 J. Pediatr. pmid:21658714
Collison KS et al. Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. 2011 Br. J. Nutr. pmid:21429276
Lund TM et al. β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons. 2011 Neurochem. Int. pmid:21684314
Hayashi T et al. Positional asphyxia or diabetic ketoacidosis? A case report. 2011 Leg Med (Tokyo) pmid:21377395
Sun AK et al. [Fabrication of larynx-shape tissue engineered cartilage by means of filling together with wrapping with pedicle myofascial flap]. 2011 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22336014
Lassala A et al. Parenteral administration of L-arginine enhances fetal survival and growth in sheep carrying multiple fetuses. 2011 J. Nutr. pmid:21430253
Asl AN et al. Prevalence of subclinical ketosis in dairy cattle in the Southwestern Iran and detection of cutoff point for NEFA and glucose concentrations for diagnosis of subclinical ketosis. 2011 Prev. Vet. Med. pmid:21439662
Schutz PW et al. Protective effects of d-3-hydroxybutyrate and propionate during hypoglycemic coma: clinical and biochemical insights from infant rats. 2011 Mol. Genet. Metab. pmid:21439874
Dasarathy S et al. Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis. 2011 Eur J Gastroenterol Hepatol pmid:21448070
Xiang Y and Shen J Simultaneous detection of cerebral metabolism of different substrates by in vivo ¹³C isotopomer MRS. 2011 J. Neurosci. Methods pmid:21419161
Sander AK et al. Ex vivo phagocytic overall performance of neutrophilic granulocytes and the relation to plasma insulin-like growth factor-I concentrations in dairy cows during the transition period. 2011 J. Dairy Sci. pmid:21426965
Huang HC et al. Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: a new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors. 2011 Biosens Bioelectron pmid:21398106
Bényei B et al. Plasma progesterone, metabolic hormones and beta-hydroxybutyrate in Holstein-Friesian cows after superovulation. 2011 Acta Vet. Hung. pmid:22079709
Budde CF et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains. 2011 Appl. Environ. Microbiol. pmid:21398488
Dutton SB et al. Protective effect of the ketogenic diet in Scn1a mutant mice. 2011 Epilepsia pmid:21801172
Hsu WY et al. Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21856256
Valayannopoulos V et al. Successful treatment of severe cardiomyopathy in glycogen storage disease type III With D,L-3-hydroxybutyrate, ketogenic and high-protein diet. 2011 Pediatr. Res. pmid:21857385
Zhang Z et al. Concentrations of sodium, potassium, magnesium, and iron in the serum of dairy cows with subclinical ketosis. 2011 Biol Trace Elem Res pmid:21739162
Shah TD et al. The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase. 2011 Mol. Biochem. Parasitol. pmid:21767577
Stenerson MB et al. Bilateral basal ganglia infarctions in a neonate born during maternal diabetic ketoacidosis. 2011 Pediatrics pmid:21807693
Norouzian MA et al. Rumen development and growth of Balouchi lambs offered alfalfa hay pre- and post-weaning. 2011 Trop Anim Health Prod pmid:21465104
Minlebaev M and Khazipov R Antiepileptic effects of endogenous beta-hydroxybutyrate in suckling infant rats. 2011 Epilepsy Res. pmid:21470827
Maurer GD et al. Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. 2011 BMC Cancer pmid:21791085
Valergakis GE et al. Phenotypic association between energy balance indicators and reproductive performance in primiparous Holstein cows. 2011 Vet. Rec. pmid:21493532
Chmiel-Perzyńska I et al. Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. 2011 Neurotox Res pmid:20838951
Dyck BL et al. Starch source and content in postpartum dairy cow diets: effects on plasma metabolites and reproductive processes. 2011 J. Dairy Sci. pmid:21854936
Tisi DK et al. Fetal exposure to altered amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1 occurs before screening for gestational diabetes mellitus. 2011 Diabetes Care pmid:20855548
Cetin H et al. Polycythaemia in infants of diabetic mothers: β-hydroxybutyrate stimulates erythropoietic activity. 2011 J. Int. Med. Res. pmid:21819713
Zhang D et al. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959534
Legge M et al. Energy substrate utilization in the common brushtailed possum (Trichosurus vulpecula) using intravenous tolerance tests. 2011 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:20977945
Zhou C and Byard RW Armanni-Ebstein phenomenon and hypothermia. 2011 Forensic Sci. Int. pmid:20875709
Al-Qudah KM Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia. 2011 Vet Clin Pathol pmid:21299584
Marinou K et al. Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men. 2011 Br. J. Nutr. pmid:21251339
Zhang ZG et al. Serum antioxidant capacity of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21257536
Tyagi R et al. Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. 2011 J Appl Toxicol pmid:21218500
Bracken RM et al. Impact of pre-exercise rapid-acting insulin reductions on ketogenesis following running in Type 1 diabetes. 2011 Diabet. Med. pmid:21219433
Hu K et al. Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero (1)H-(13)C HSQC (HSQC(0)). 2011 J. Am. Chem. Soc. pmid:21247157
Bielohuby M et al. Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20943751
Alvarez-Rodríguez J et al. Metabolic and luteal function in winter-calving Spanish beef cows as affected by calf management and breed. 2010 J Anim Physiol Anim Nutr (Berl) pmid:19663981
van Delft R et al. Blood beta-hydroxybutyrate correlates better with seizure reduction due to ketogenic diet than do ketones in the urine. 2010 Seizure pmid:19962324
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Hajiali H et al. Preparation of a novel biodegradable nanocomposite scaffold based on poly (3-hydroxybutyrate)/bioglass nanoparticles for bone tissue engineering. 2010 J Mater Sci Mater Med pmid:20372984
Denny CA et al. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice. 2010 J. Neurochem. pmid:20374428
Kim do Y et al. Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors. 2010 J. Neurochem. pmid:20374433
Boyle WA et al. Storms drive altitudinal migration in a tropical bird. 2010 Proc. Biol. Sci. pmid:20375047
Wood CM et al. The influence of feeding and fasting on plasma metabolites in the dogfish shark (Squalus acanthias). 2010 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:19782147
Hartman AL et al. Seizure tests distinguish intermittent fasting from the ketogenic diet. 2010 Epilepsia pmid:20477852
Quiroz-Rocha GF et al. Short communication: Effect of sampling time relative to the first daily feeding on interpretation of serum fatty acid and beta-hydroxybutyrate concentrations in dairy cattle. 2010 J. Dairy Sci. pmid:20412917
Zhang YQ et al. Effect of a mixture of steam-flaked corn and soybeans on health, growth, and selected blood metabolism of Holstein calves. 2010 J. Dairy Sci. pmid:20412943
Laeger T et al. Role of beta-hydroxybutyric acid in the central regulation of energy balance. 2010 Appetite pmid:20416348
Voyvoda H and Erdogan H Use of a hand-held meter for detecting subclinical ketosis in dairy cows. 2010 Res. Vet. Sci. pmid:20471047
Forslund KB et al. Low cortisol levels in blood from dairy cows with ketosis: a field study. 2010 Acta Vet. Scand. pmid:20487518
Gasior M et al. Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. 2010 Epilepsia pmid:20491877
Lucidi P et al. Mechanisms of insulin resistance after insulin-induced hypoglycemia in humans: the role of lipolysis. 2010 Diabetes pmid:20299466
Westerbacka J et al. Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. 2010 Gastroenterology pmid:20600015
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
LeBlanc S Monitoring metabolic health of dairy cattle in the transition period. 2010 J. Reprod. Dev. pmid:20629214
Pedersen SM et al. The serum metabolite response to diet intervention with probiotic acidified milk in irritable bowel syndrome patients is indistinguishable from that of non-probiotic acidified milk by 1H NMR-based metabonomic analysis. 2010 Nutrients pmid:22254002
Veldhorst MA et al. Presence or absence of carbohydrates and the proportion of fat in a high-protein diet affect appetite suppression but not energy expenditure in normal-weight human subjects fed in energy balance. 2010 Br. J. Nutr. pmid:20565999
Kashiwaya Y et al. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. 2010 J. Biol. Chem. pmid:20529850
Thaler S et al. Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat--possible involvement of kynurenic acid. 2010 Graefes Arch. Clin. Exp. Ophthalmol. pmid:20532550
Seong SH et al. L-carnitine-supplemented parenteral nutrition improves fat metabolism but fails to support compensatory growth in premature Korean infants. 2010 Nutr Res pmid:20534325
Zhang C et al. Folate-mediated poly(3-hydroxybutyrate-co-3-hydroxyoctanoate) nanoparticles for targeting drug delivery. 2010 Eur J Pharm Biopharm pmid:20472060
Kelly AK et al. Repeatability of feed efficiency, carcass ultrasound, feeding behavior, and blood metabolic variables in finishing heifers divergently selected for residual feed intake. 2010 J. Anim. Sci. pmid:20525931
Zeugswetter F et al. Efficacy of plasma beta-hydroxybutyrate concentration as a marker for diabetes mellitus in acutely sick cats. 2010 J. Feline Med. Surg. pmid:20117951
Fisher AD et al. The effects of 12, 30, or 48 hours of road transport on the physiological and behavioral responses of sheep. 2010 J. Anim. Sci. pmid:20154169
Samoilova M et al. Chronic in vitro ketosis is neuroprotective but not anti-convulsant. 2010 J. Neurochem. pmid:20163521
Song H et al. Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20179248
Ramnanan CJ et al. Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo. 2010 Diabetes pmid:20185816
Kafi M and Mirzaei A Effects of first postpartum progesterone rise, metabolites, milk yield, and body condition score on the subsequent ovarian activity and fertility in lactating Holstein dairy cows. 2010 Trop Anim Health Prod pmid:20140511
Stout PA et al. Quantitative analysis of gamma-hydroxybutyrate at endogenous concentrations in hair using liquid chromatography tandem mass spectrometry. 2010 J. Forensic Sci. pmid:20141559
Fürll M et al. Effect of multiple intravenous injections of butaphosphan and cyanocobalamin on the metabolism of periparturient dairy cows. 2010 J. Dairy Sci. pmid:20723690
Oliveira RA et al. Effects of feeding polyphenols from pomegranate extract on health, growth, nutrient digestion, and immunocompetence of calves. 2010 J. Dairy Sci. pmid:20723701
Meier S et al. Effects of divergent Holstein-Friesian strain and diet on diurnal patterns of plasma metabolites and hormones. 2010 J. Dairy Res. pmid:20822560
Zhang XX and Rainey PB Bet hedging in the underworld. 2010 Genome Biol. pmid:21062509
Henderson DW and Schlesinger DP Use of a point-of-care beta-hydroxybutyrate sensor for detection of ketonemia in dogs. 2010 Can. Vet. J. pmid:21119867
Kirmse K et al. GABA depolarizes immature neocortical neurons in the presence of the ketone body ß-hydroxybutyrate. 2010 J. Neurosci. pmid:21106838
Stasiak P et al. In vivo assessment of parenteral formulations of oligo(3-hydroxybutyric Acid) conjugates with the model compound Ibuprofen. 2010 AAPS PharmSciTech pmid:21088943
Rivera N et al. Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs. 2010 J. Clin. Invest. pmid:21084754
Wagner SA and Schimek DE Evaluation of the effect of bolus administration of 50% dextrose solution on measures of electrolyte and energy balance in postpartum dairy cows. 2010 Am. J. Vet. Res. pmid:20807148
Kalaitzakis E et al. Clinicopathological evaluation of downer dairy cows with fatty liver. 2010 Can. Vet. J. pmid:20808573
Morgante M et al. Preliminary study on metabolic profile of pregnant and non-pregnant ewes with high or low degree of behavioral lateralization. 2010 Anim. Sci. J. pmid:21108694