(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Genomic Instability D042822 7 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Septo-Optic Dysplasia D025962 1 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Ulnar Neuropathies D020424 1 associated lipids
Median Neuropathy D020423 1 associated lipids
Intracranial Hemorrhages D020300 2 associated lipids
Heredodegenerative Disorders, Nervous System D020271 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Authors Title Published Journal PubMed Link
Kurihara M et al. Inhibitory effect of β-hydroxybutyric acid on L-type Ca(2+) current under β-adrenergic stimulation in guinea pig cardiac ventricular myocytes. 2012 Fukushima J Med Sci pmid:23237870
Zhang J et al. NMR-based metabolomics study of canine bladder cancer. 2012 Biochim. Biophys. Acta pmid:22967815
Abdelwahab MG et al. The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma. 2012 PLoS ONE pmid:22563484
Anis SN et al. Enhanced recovery and purification of P(3HB-co-3HHx) from recombinant Cupriavidus necator using alkaline digestion method. 2012 Appl. Biochem. Biotechnol. pmid:22569781
Bjerre-Harpøth V et al. Metabolic and production profiles of dairy cows in response to decreased nutrient density to increase physiological imbalance at different stages of lactation. 2012 J. Dairy Sci. pmid:22541465
Lomander H et al. Supplemental feeding with glycerol or propylene glycol of dairy cows in early lactation--effects on metabolic status, body condition, and milk yield. 2012 J. Dairy Sci. pmid:22541468
Mueller D et al. Biotransformation of diclofenac and effects on the metabolome of primary human hepatocytes upon repeated dose exposure. 2012 Eur J Pharm Sci pmid:22330146
Laarman AH et al. Effects of feeding a calf starter on molecular adaptations in the ruminal epithelium and liver of Holstein dairy calves. 2012 J. Dairy Sci. pmid:22541487
Yuan K et al. Effect of rumen-protected niacin on lipid metabolism, oxidative stress, and performance of transition dairy cows. 2012 J. Dairy Sci. pmid:22541495
Lei J et al. Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells. 2012 Amino Acids pmid:22543725
Roberts T et al. Metabolic parameters in transition cows as indicators for early-lactation culling risk. 2012 J. Dairy Sci. pmid:22612941
Stocks SE and Allen MS Hypophagic effects of propionate increase with elevated hepatic acetyl coenzyme A concentration for cows in the early postpartum period. 2012 J. Dairy Sci. pmid:22612960
Prevost M et al. Repeated intoxication presenting with azotemia, elevated serum osmolal gap, and metabolic acidosis with high anion gap: differential diagnosis, management, and prognosis. 2012 Int Urol Nephrol pmid:20602169
Saadeh M et al. Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol. 2012 PLoS ONE pmid:22272304
Oh SJ et al. Hepatic expression of cytochrome P450 in type 2 diabetic Goto-Kakizaki rats. 2012 Chem. Biol. Interact. pmid:22244987
Weingart C et al. Validation of a portable hand-held whole-blood ketone meter for use in cats. 2012 Vet Clin Pathol pmid:22250845
Krueger T and Melendez P Effect of ghrelin on feed intake and metabolites in lambs. 2012 Appetite pmid:22280977
Ster C et al. Effect of postcalving serum nonesterified fatty acids concentration on the functionality of bovine immune cells. 2012 J. Dairy Sci. pmid:22281335
Palmiere C et al. Is the formula of Traub still up to date in antemortem blood glucose level estimation? 2012 Int. J. Legal Med. pmid:22327538
Yang MJ et al. Bioconversion of ethyl (R)-4-cyano-3-hydroxybutyate into (R)-ethyl-3-hydroxyglutarate via an indirect pathway by Rhodococcus boritolerans. 2012 Biotechnol. Lett. pmid:22261862
van der Drift SG et al. Genetic and nongenetic variation in plasma and milk β-hydroxybutyrate and milk acetone concentrations of early-lactation dairy cows. 2012 J. Dairy Sci. pmid:22939798
Gözke G et al. Electrofiltration as a purification strategy for microbial poly-(3-hydroxybutyrate). 2012 Bioresour. Technol. pmid:22940329
Martin R et al. [Relationships between different parameters for the evaluation of the energy balance and the differential cell count in milk from cows with healthy udders]. 2012 Tierarztl Prax Ausg G Grosstiere Nutztiere pmid:22911228
Palmiere C et al. Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports. 2012 Leg Med (Tokyo) pmid:22177826
Palmiere C et al. Blood, urine and vitreous isopropyl alcohol as biochemical markers in forensic investigations. 2012 Leg Med (Tokyo) pmid:22177827
Hancock SN et al. Size at birth and adult fat mass in twin sheep are determined in early gestation. 2012 J. Physiol. (Lond.) pmid:22183720
Gao F et al. Effect of prepartum maternal energy density on the growth performance, immunity, and antioxidation capability of neonatal calves. 2012 J. Dairy Sci. pmid:22818465
Kawata Y et al. Efficient secreted production of (R)-3-hydroxybutyric acid from living Halomonas sp. KM-1 under successive aerobic and microaerobic conditions. 2012 Appl. Microbiol. Biotechnol. pmid:22718250
Maillo V et al. Influence of lactation on metabolic characteristics and embryo development in postpartum Holstein dairy cows. 2012 J. Dairy Sci. pmid:22720941
Kelso EJ et al. Sex differences in fuel use and metabolism during development in fasting juvenile northern elephant seals. 2012 J. Exp. Biol. pmid:22786640
Luan G et al. Ketogenic diet reduces Smac/Diablo and cytochrome c release and attenuates neuronal death in a mouse model of limbic epilepsy. 2012 Brain Res. Bull. pmid:22796483
Doelman J et al. Transcript profiling of the ruminant liver indicates a unique program of transcriptional regulation of ketogenic enzymes during food restriction. 2012 Comp. Biochem. Physiol. Part D Genomics Proteomics pmid:22748507
Fraga CM et al. Fatty acids oxidation and alternative energy sources detected in Taenia crassiceps cysticerci after host treatment with antihelminthic drugs. 2012 Exp. Parasitol. pmid:22465501
Borchardt S and Staufenbiel R Evaluation of the use of nonesterified fatty acids and β-hydroxybutyrate concentrations in pooled serum samples for herd-based detection of subclinical ketosis in dairy cows during the first week after parturition. 2012 J. Am. Vet. Med. Assoc. pmid:22471831
Blad CC et al. Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A). 2012 J. Med. Chem. pmid:22420767
Hosseini A et al. Differential effects of propionate or β-hydroxybutyrate on genes related to energy balance and insulin sensitivity in bovine white adipose tissue explants from a subcutaneous and a visceral depot. 2012 J Anim Physiol Anim Nutr (Berl) pmid:21635577
Senosy WS et al. Influences of metabolic traits on subclinical endometritis at different intervals postpartum in high milking cows. 2012 Reprod. Domest. Anim. pmid:22053752
Mestdagh R et al. Gut microbiota modulate the metabolism of brown adipose tissue in mice. 2012 J. Proteome Res. pmid:22053906
Chee JY et al. Expression of Aeromonas caviae polyhydroxyalkanoate synthase gene in Burkholderia sp. USM (JCM15050) enables the biosynthesis of SCL-MCL PHA from palm oil products. 2012 J. Appl. Microbiol. pmid:22054430
Zhou C and Byard RW Basal renal tubular epithelial cell vacuolization and alcoholic ketoacidosis. 2012 J. Forensic Sci. pmid:22074296
Eitam H et al. Protein deprivation attenuates Hsp expression in fat tissue. 2012 Cell Stress Chaperones pmid:22081321
McCarthy B et al. The effect of stocking rate and calving date on reproductive performance, body state, and metabolic and health parameters of Holstein-Friesian dairy cows. 2012 J. Dairy Sci. pmid:22365215
Mulier KE et al. Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock. 2012 Resuscitation pmid:21864484
Rehman HU A woman with ketoacidosis but not diabetes. 2012 BMJ pmid:22381524
Parkkila S et al. Serendipitous fragment-based drug discovery: ketogenic diet metabolites and statins effectively inhibit several carbonic anhydrases. 2012 Chem. Commun. (Camb.) pmid:22382897
Devenny JJ et al. Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. 2012 Obesity (Silver Spring) pmid:22402735
Walsh SW et al. Effect of the metabolic environment at key stages of follicle development in cattle: focus on steroid biosynthesis. 2012 Physiol. Genomics pmid:22414914
Dutta T et al. Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes. 2012 Diabetes pmid:22415876
Sui L et al. Effect of poly-β-hydroxybutyrate on Chinese mitten crab, Eriocheir sinensis, larvae challenged with pathogenic Vibrio anguillarum. 2012 J. Fish Dis. pmid:22417317
Thompson IM et al. Effects of lactation and pregnancy on metabolic and hormonal responses and expression of selected conceptus and endometrial genes of Holstein dairy cattle. 2012 J. Dairy Sci. pmid:22863093
Chapinal N et al. Herd-level association of serum metabolites in the transition period with disease, milk production, and early lactation reproductive performance. 2012 J. Dairy Sci. pmid:22863094
Ghorbani A et al. Performance and metabolic responses of Holstein calves to supplemental chromium in colostrum and milk. 2012 J. Dairy Sci. pmid:22863099
Heidarpour M et al. Acute-phase protein concentration and metabolic status affect the outcome of treatment in cows with clinical and subclinical endometritis. 2012 Vet. Rec. pmid:22865113
Tsutsui H et al. Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS. 2012 Anal Bioanal Chem pmid:22895741
Yum MS et al. β-Hydroxybutyrate increases the pilocarpine-induced seizure threshold in young mice. 2012 Brain Dev. pmid:21723679
Chen CM et al. Construction of a light-emitting diode fluorescence detector for high-performance liquid chromatography and its application to fluorometric determination of L-3-hydroxybutyrate. 2012 Biomed. Chromatogr. pmid:21594881
Lü H et al. [Biocompatibility of surface modified PHBHHx with rat embryonic neural stem cells]. 2012 Sheng Wu Gong Cheng Xue Bao pmid:23311136
Liu SF et al. Dioscorea alata attenuates renal interstitial cellular fibrosis by regulating Smad- and epithelial-mesenchymal transition signaling pathways. 2012 PLoS ONE pmid:23144821
Smejkal P et al. Separation of carboxylic acids in human serum by isotachophoresis using a commercial field-deployable analytical platform combined with in-house glass microfluidic chips. 2012 Anal. Chim. Acta pmid:23146402
Constantin RP et al. Prooxidant activity of fisetin: effects on energy metabolism in the rat liver. 2011 Mar-Apr J. Biochem. Mol. Toxicol. pmid:20957679
Rodríguez-Merchán B et al. [Capillary beta-hydroxybutyrate determination for monitoring diabetic ketoacidosis]. 2011 Aug-Sep Endocrinol Nutr pmid:21737365
Brunner MP et al. Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization. 2011 Circ Cardiovasc Genet pmid:22010138
Moazzami AA et al. Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients. 2011 J. Nutr. pmid:22013201
Chapinal N et al. The association of serum metabolites with clinical disease during the transition period. 2011 J. Dairy Sci. pmid:21943741
Kreipe L et al. First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in nonketotic early lactating cows. 2011 J. Dairy Sci. pmid:21943742
Stutchbury BJ et al. Effects of post-breeding moult and energetic condition on timing of songbird migration into the tropics. 2011 Proc. Biol. Sci. pmid:20659932
Ashby RD et al. Biopolymer scaffolds for use in delivering antimicrobial sophorolipids to the acne-causing bacterium Propionibacterium acnes. 2011 N Biotechnol pmid:20708720
Harris DL et al. Cot-side electroencephalography monitoring is not clinically useful in the detection of mild neonatal hypoglycemia. 2011 J. Pediatr. pmid:21658714
Collison KS et al. Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. 2011 Br. J. Nutr. pmid:21429276
Lund TM et al. β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons. 2011 Neurochem. Int. pmid:21684314
Hayashi T et al. Positional asphyxia or diabetic ketoacidosis? A case report. 2011 Leg Med (Tokyo) pmid:21377395
Sun AK et al. [Fabrication of larynx-shape tissue engineered cartilage by means of filling together with wrapping with pedicle myofascial flap]. 2011 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22336014
Lassala A et al. Parenteral administration of L-arginine enhances fetal survival and growth in sheep carrying multiple fetuses. 2011 J. Nutr. pmid:21430253
Asl AN et al. Prevalence of subclinical ketosis in dairy cattle in the Southwestern Iran and detection of cutoff point for NEFA and glucose concentrations for diagnosis of subclinical ketosis. 2011 Prev. Vet. Med. pmid:21439662
Schutz PW et al. Protective effects of d-3-hydroxybutyrate and propionate during hypoglycemic coma: clinical and biochemical insights from infant rats. 2011 Mol. Genet. Metab. pmid:21439874
Dasarathy S et al. Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis. 2011 Eur J Gastroenterol Hepatol pmid:21448070
Xiang Y and Shen J Simultaneous detection of cerebral metabolism of different substrates by in vivo ¹³C isotopomer MRS. 2011 J. Neurosci. Methods pmid:21419161
Sander AK et al. Ex vivo phagocytic overall performance of neutrophilic granulocytes and the relation to plasma insulin-like growth factor-I concentrations in dairy cows during the transition period. 2011 J. Dairy Sci. pmid:21426965
Huang HC et al. Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: a new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors. 2011 Biosens Bioelectron pmid:21398106
Budde CF et al. Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from plant oil by engineered Ralstonia eutropha strains. 2011 Appl. Environ. Microbiol. pmid:21398488
Ding Y et al. Production of fumaric acid by Rhizopus oryzae: role of carbon-nitrogen ratio. 2011 Appl. Biochem. Biotechnol. pmid:21416336
Zhang Z et al. Concentrations of sodium, potassium, magnesium, and iron in the serum of dairy cows with subclinical ketosis. 2011 Biol Trace Elem Res pmid:21739162
Shah TD et al. The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase. 2011 Mol. Biochem. Parasitol. pmid:21767577
Stenerson MB et al. Bilateral basal ganglia infarctions in a neonate born during maternal diabetic ketoacidosis. 2011 Pediatrics pmid:21807693
Maurer GD et al. Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. 2011 BMC Cancer pmid:21791085
Dyck BL et al. Starch source and content in postpartum dairy cow diets: effects on plasma metabolites and reproductive processes. 2011 J. Dairy Sci. pmid:21854936
Cetin H et al. Polycythaemia in infants of diabetic mothers: β-hydroxybutyrate stimulates erythropoietic activity. 2011 J. Int. Med. Res. pmid:21819713
Mizutani T et al. Diagnosis of fulminant type 1 diabetes mellitus in an autopsy case with postmortem changes. 2011 Leg Med (Tokyo) pmid:21821459
Moriel P et al. Camelina meal and crude glycerin as feed supplements for developing replacement beef heifers. 2011 J. Anim. Sci. pmid:21821818
Zhang D et al. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959534
Legge M et al. Energy substrate utilization in the common brushtailed possum (Trichosurus vulpecula) using intravenous tolerance tests. 2011 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:20977945
Zhou C and Byard RW Armanni-Ebstein phenomenon and hypothermia. 2011 Forensic Sci. Int. pmid:20875709
Al-Qudah KM Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia. 2011 Vet Clin Pathol pmid:21299584
Marinou K et al. Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men. 2011 Br. J. Nutr. pmid:21251339
Zhang ZG et al. Serum antioxidant capacity of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21257536
Tyagi R et al. Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. 2011 J Appl Toxicol pmid:21218500
Bracken RM et al. Impact of pre-exercise rapid-acting insulin reductions on ketogenesis following running in Type 1 diabetes. 2011 Diabet. Med. pmid:21219433
Hu K et al. Simultaneous quantification and identification of individual chemicals in metabolite mixtures by two-dimensional extrapolated time-zero (1)H-(13)C HSQC (HSQC(0)). 2011 J. Am. Chem. Soc. pmid:21247157
Arica V et al. Beta-ketothiolase deficiency brought with lethargy: case report. 2011 Hum Exp Toxicol pmid:21247997
Sznajder A and Jendrossek D Biochemical characterization of a new type of intracellular PHB depolymerase from Rhodospirillum rubrum with high hydrolytic activity on native PHB granules. 2011 Appl. Microbiol. Biotechnol. pmid:21274528