(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Mastitis, Bovine D008414 8 associated lipids
Metabolic Diseases D008659 12 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Muscle Rigidity D009127 4 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Neural Tube Defects D009436 5 associated lipids
Obesity D009765 29 associated lipids
Obesity, Morbid D009767 8 associated lipids
Pallor D010167 1 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease D010300 53 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Placental Insufficiency D010927 6 associated lipids
Plant Poisoning D010939 5 associated lipids
Pregnancy Complications D011248 19 associated lipids
Puerperal Disorders D011644 4 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Reye Syndrome D012202 14 associated lipids
Sandhoff Disease D012497 2 associated lipids
Seizures D012640 87 associated lipids
Sheep Diseases D012757 10 associated lipids
Shock D012769 11 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Spasms, Infantile D013036 3 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Starvation D013217 47 associated lipids
Status Epilepticus D013226 1 associated lipids
Stomach Diseases D013272 7 associated lipids
Syndrome D013577 4 associated lipids
Thinness D013851 11 associated lipids
Thyrotoxicosis D013971 3 associated lipids
Trematode Infections D014201 8 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Trypanosomiasis, African D014353 5 associated lipids
Uremia D014511 33 associated lipids
Uterine Diseases D014591 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Vomiting D014839 21 associated lipids
Spinal Muscular Atrophies of Childhood D014897 1 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Wrist Injuries D014954 1 associated lipids
Fructose-1,6-Diphosphatase Deficiency D015319 1 associated lipids
Pyruvate Metabolism, Inborn Errors D015323 3 associated lipids
Pyruvate Dehydrogenase Complex Deficiency Disease D015325 3 associated lipids
Reperfusion Injury D015427 65 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Critical Illness D016638 13 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Encephalopathy, Bovine Spongiform D016643 2 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Liver Failure D017093 5 associated lipids
Hyperandrogenism D017588 5 associated lipids
Glucose Intolerance D018149 13 associated lipids
Adenocarcinoma, Clear Cell D018262 1 associated lipids
Placenta, Retained D018457 3 associated lipids
Multiple Endocrine Neoplasia Type 1 D018761 2 associated lipids
HIV Wasting Syndrome D019247 3 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Basal Ganglia Cerebrovascular Disease D020144 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Heredodegenerative Disorders, Nervous System D020271 1 associated lipids
Intracranial Hemorrhages D020300 2 associated lipids
Median Neuropathy D020423 1 associated lipids
Ulnar Neuropathies D020424 1 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Septo-Optic Dysplasia D025962 1 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Genomic Instability D042822 7 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Malnutrition D044342 6 associated lipids
Congenital Hyperinsulinism D044903 1 associated lipids
Pancreatitis, Chronic D050500 1 associated lipids
Lipid Metabolism Disorders D052439 3 associated lipids
Azotemia D053099 1 associated lipids
Lethargy D053609 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Disease Resistance D060467 12 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Liu M and Swanson DL Physiological evidence that anthropogenic woodlots can substitute for native riparian woodlands as stopover habitat for migrant birds. 2014 Jan-Feb Physiol. Biochem. Zool. pmid:24457932
Insomphun C et al. Modification of β-oxidation pathway in Ralstonia eutropha for production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from soybean oil. 2014 J. Biosci. Bioeng. pmid:23999062
Palmiere C et al. Postmortem distribution of 3-beta-hydroxybutyrate. 2014 J. Forensic Sci. pmid:23980658
González-García E et al. Circannual body reserve dynamics and metabolic profile changes in Romane ewes grazing on rangelands. 2014 Domest. Anim. Endocrinol. pmid:24188681
Kabara E et al. Adiponectin links adipose tissue function and monocyte inflammatory responses during bovine metabolic stress. 2014 Comp. Immunol. Microbiol. Infect. Dis. pmid:24296305
Newman JC and Verdin E Ketone bodies as signaling metabolites. 2014 Trends Endocrinol. Metab. pmid:24140022
Cevasco G et al. HPLC determination of D-3-hydroxybutyric acid by derivatization with a benzofurazan reagent and fluorescent detection: application in the analysis of human plasma. 2014 Clin. Chim. Acta pmid:24315779
Torri C et al. Fast procedure for the analysis of poly(hydroxyalkanoates) in bacterial cells by off-line pyrolysis/gas-chromatography with flame ionization detector. 2014 J Chromatogr A pmid:25069742
He Y et al. Evaluation of PHBHHx and PHBV/PLA fibers used as medical sutures. 2014 J Mater Sci Mater Med pmid:24178983
Le Foll C et al. Regulation of hypothalamic neuronal sensing and food intake by ketone bodies and fatty acids. 2014 Diabetes pmid:24379353
Du Z et al. 1H-NMR-based metabolic analysis of human serum reveals novel markers of myocardial energy expenditure in heart failure patients. 2014 PLoS ONE pmid:24505394
Lu HX et al. Low concentration of serum helps to maintain the characteristics of NSCs/NPCs on alkali-treated PHBHHx film in vitro. 2014 Neurol. Res. pmid:24512014
Fan MR et al. Tissue engineered esophagus scaffold constructed with porcine small intestinal submucosa and synthetic polymers. 2014 Biomed Mater pmid:24457267
Lu XY et al. Microbial synthesized biodegradable PHBHHxPEG hybrid copolymer as an efficient intracellular delivery nanocarrier for kinase inhibitor. 2014 BMC Biotechnol. pmid:24438107
Valour D et al. Energy and lipid metabolism gene expression of D18 embryos in dairy cows is related to dam physiological status. 2014 Physiol. Genomics pmid:24220328
Mavrogianni VS et al. Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period. 2014 Res. Vet. Sci. pmid:24331730
Wei T et al. Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney. 2014 Biochem. Biophys. Res. Commun. pmid:24755084
Lertwattanarak R and Plainkum P Efficacy of quantitative capillary beta-hydroxybutyrate measurement in the diagnosis of diabetic ketoacidosis: a comparison to quantitative serum ketone measurement by nitroprusside reaction. 2014 J Med Assoc Thai pmid:24772583
Kulka M et al. Serum paraoxonase-1 activity of dairy Holstein-Fresian cows in different lactation stages--preliminary study. 2014 Pol J Vet Sci pmid:24724482
Yang Q et al. The properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) and its applications in tissue engineering. 2014 Curr Stem Cell Res Ther pmid:24524792
Qiu C et al. Early pregnancy urinary biomarkers of fatty acid and carbohydrate metabolism in pregnancies complicated by gestational diabetes. 2014 Diabetes Res. Clin. Pract. pmid:24703806
Duehlmeier R et al. Insulin sensitivity during late gestation in ewes affected by pregnancy toxemia and in ewes with high and low susceptibility to this disorder. 2013 Mar-Apr J. Vet. Intern. Med. pmid:23397990
[Prospective multicenter study on long-term ketogenic diet therapy for intractable childhood epilepsy]. 2013 Zhonghua Er Ke Za Zhi pmid:23927801
Malloy VL et al. Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. 2013 Metab. Clin. Exp. pmid:23928105
Reinke SN et al. 1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy. 2013 J. Proteome Res. pmid:23931672
Fukumori R et al. Ingestion of medium chain fatty acids by lactating dairy cows increases concentrations of plasma ghrelin. 2013 Domest. Anim. Endocrinol. pmid:24209506
Ho CF et al. Ketone bodies upregulate endothelial connexin 43 (Cx43) gap junctions. 2013 Vet. J. pmid:24210276
Wang J et al. Metabolic products of [2-(13) C]ethanol in the rat brain after chronic ethanol exposure. 2013 J. Neurochem. pmid:24033360
Sumithran P et al. Ketosis and appetite-mediating nutrients and hormones after weight loss. 2013 Eur J Clin Nutr pmid:23632752
Won YJ et al. β-Hydroxybutyrate modulates N-type calcium channels in rat sympathetic neurons by acting as an agonist for the G-protein-coupled receptor FFA3. 2013 J. Neurosci. pmid:24305827
Hodgson AB et al. Metabolic response to green tea extract during rest and moderate-intensity exercise. 2013 J. Nutr. Biochem. pmid:22974973
Riedel SL et al. Recovery of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from Ralstonia eutropha cultures with non-halogenated solvents. 2013 Biotechnol. Bioeng. pmid:22903730
Rutty GN et al. The effect on toxicology, biochemistry and immunology investigations by the use of targeted post-mortem computed tomography angiography. 2013 Forensic Sci. Int. pmid:22704555
Masaeli E et al. Fabrication, characterization and cellular compatibility of poly(hydroxy alkanoate) composite nanofibrous scaffolds for nerve tissue engineering. 2013 PLoS ONE pmid:23468923
Suthar VS et al. Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. 2013 J. Dairy Sci. pmid:23497997
Laeger T et al. Concentrations of hormones and metabolites in cerebrospinal fluid and plasma of dairy cows during the periparturient period. 2013 J. Dairy Sci. pmid:23498004
Zarrin M et al. Long-term elevation of β-hydroxybutyrate in dairy cows through infusion: effects on feed intake, milk production, and metabolism. 2013 J. Dairy Sci. pmid:23498021
Lim JS et al. Effect of composition ratio on the thermal and physical properties of semicrystalline PLA/PHB-HHx composites. 2013 Mater Sci Eng C Mater Biol Appl pmid:23498241
Ruskin DN et al. Ketogenic diets and thermal pain: dissociation of hypoalgesia, elevated ketones, and lowered glucose in rats. 2013 J Pain pmid:23499319
Moyes KM et al. Generation of an index for physiological imbalance and its use as a predictor of primary disease in dairy cows during early lactation. 2013 J. Dairy Sci. pmid:23403197
Klevenhusen F et al. Feeding barley grain-rich diets altered electrophysiological properties and permeability of the ruminal wall in a goat model. 2013 J. Dairy Sci. pmid:23403198
Lehmann M et al. Concomitant lipopolysaccharide-induced transfer of blood-derived components including immunoglobulins into milk. 2013 J. Dairy Sci. pmid:23219120
Shimazu T et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 2013 Science pmid:23223453
Peng Q et al. The implantable and biodegradable PHBHHx 3D scaffolds loaded with protein-phospholipid complex for sustained delivery of proteins. 2013 Pharm. Res. pmid:23224980
Lin BQ et al. Dietary restriction suppresses tumor growth, reduces angiogenesis, and improves tumor microenvironment in human non-small-cell lung cancer xenografts. 2013 Lung Cancer pmid:23199512
Courchesne-Loyer A et al. Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism. 2013 Nutrition pmid:23274095
Bohlooli M et al. Thermodynamics of a molten globule state of human serum albumin by 3-β-hydroxybutyrate as a ketone body. 2013 Int. J. Biol. Macromol. pmid:23262385
Shimomura T et al. A novel, disposable, screen-printed amperometric biosensor for ketone 3-β-hydroxybutyrate fabricated using a 3-β-hydroxybutyrate dehydrogenase-mesoporous silica conjugate. 2013 Anal Bioanal Chem pmid:23096941
Memon S and Pratten MK Teratogenic effects of diabetic conditions in chick heart in ovo and in micromass culture may be prevented by addition of vitamin C and folic acid. 2013 Reprod. Toxicol. pmid:23099339
Cheng B et al. d-β-Hydroxybutyrate inhibited the apoptosis of PC12 cells induced by H2O2 via inhibiting oxidative stress. 2013 Neurochem. Int. pmid:23022628