(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Mastitis, Bovine D008414 8 associated lipids
Metabolic Diseases D008659 12 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Muscle Rigidity D009127 4 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Neural Tube Defects D009436 5 associated lipids
Obesity D009765 29 associated lipids
Obesity, Morbid D009767 8 associated lipids
Pallor D010167 1 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Parkinson Disease D010300 53 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Placental Insufficiency D010927 6 associated lipids
Plant Poisoning D010939 5 associated lipids
Pregnancy Complications D011248 19 associated lipids
Puerperal Disorders D011644 4 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Reye Syndrome D012202 14 associated lipids
Sandhoff Disease D012497 2 associated lipids
Seizures D012640 87 associated lipids
Sheep Diseases D012757 10 associated lipids
Shock D012769 11 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Sleep Deprivation D012892 5 associated lipids
Spasms, Infantile D013036 3 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Starvation D013217 47 associated lipids
Status Epilepticus D013226 1 associated lipids
Stomach Diseases D013272 7 associated lipids
Syndrome D013577 4 associated lipids
Thinness D013851 11 associated lipids
Thyrotoxicosis D013971 3 associated lipids
Trematode Infections D014201 8 associated lipids
Trichostrongyloidiasis D014252 7 associated lipids
Trypanosomiasis, African D014353 5 associated lipids
Uremia D014511 33 associated lipids
Uterine Diseases D014591 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Vomiting D014839 21 associated lipids
Spinal Muscular Atrophies of Childhood D014897 1 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Wrist Injuries D014954 1 associated lipids
Fructose-1,6-Diphosphatase Deficiency D015319 1 associated lipids
Pyruvate Metabolism, Inborn Errors D015323 3 associated lipids
Pyruvate Dehydrogenase Complex Deficiency Disease D015325 3 associated lipids
Reperfusion Injury D015427 65 associated lipids
Weight Gain D015430 101 associated lipids
Weight Loss D015431 56 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Critical Illness D016638 13 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Encephalopathy, Bovine Spongiform D016643 2 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Liver Failure D017093 5 associated lipids
Hyperandrogenism D017588 5 associated lipids
Glucose Intolerance D018149 13 associated lipids
Adenocarcinoma, Clear Cell D018262 1 associated lipids
Placenta, Retained D018457 3 associated lipids
Multiple Endocrine Neoplasia Type 1 D018761 2 associated lipids
HIV Wasting Syndrome D019247 3 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Basal Ganglia Cerebrovascular Disease D020144 1 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Heredodegenerative Disorders, Nervous System D020271 1 associated lipids
Intracranial Hemorrhages D020300 2 associated lipids
Median Neuropathy D020423 1 associated lipids
Ulnar Neuropathies D020424 1 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Septo-Optic Dysplasia D025962 1 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Genomic Instability D042822 7 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Malnutrition D044342 6 associated lipids
Congenital Hyperinsulinism D044903 1 associated lipids
Pancreatitis, Chronic D050500 1 associated lipids
Lipid Metabolism Disorders D052439 3 associated lipids
Azotemia D053099 1 associated lipids
Lethargy D053609 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Disease Resistance D060467 12 associated lipids
Fetal Alcohol Spectrum Disorders D063647 6 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Patterson CE et al. Integrated substrate utilization by perinatal lung. 1986 Exp. Lung Res. pmid:3948812
Wagner S et al. Carnitine metabolism in isolated rat kidney cortex tubules. 1986 Biol. Chem. Hoppe-Seyler pmid:3954891
Bougneres PF et al. Determination of ketone body kinetics using a D-(-)-3-hydroxy[4,4,4-2H3]butyrate tracer. 1986 J. Lipid Res. pmid:3958624
Evans SE et al. Fluid therapy for induced labour under epidural analgesia: biochemical consequences for mother and infant. 1986 Br J Obstet Gynaecol pmid:3964608
Mercer DW et al. Monitoring therapy with insulin in ketoacidotic patients by quantifying 3-hydroxybutyrate with a commercial kit. 1986 Clin. Chem. pmid:3079681
Maiz A et al. Effect of DL-3-hydroxybutyrate infusions on leucine and glucose kinetics in burned rats receiving TPN. 1986 J. Nutr. pmid:3080557
Fulop M et al. Plasma lactate and 3-hydroxybutyrate levels in patients with acute ethanol intoxication. 1986 Am. J. Med. pmid:3080879
Lopes-Cardozo M et al. Acetoacetate and glucose as lipid precursors and energy substrates in primary cultures of astrocytes and neurons from mouse cerebral cortex. 1986 J. Neurochem. pmid:3081684
Keller U et al. Protein-sparing therapy in the postoperative period. 1986 World J Surg pmid:3083595
HÃ¥kanson E et al. Effect of adrenaline on exchange of free fatty acids in leg tissues and splanchnic area. A comparison with the metabolic response to surgical stress. 1986 Clin Physiol pmid:3780168
Beylot M et al. Determination of human ketone body kinetics using stable-isotope labelled tracers. 1986 Diabetologia pmid:3699302
Wu PY et al. Medium-chain triglycerides in infant formulas and their relation to plasma ketone body concentrations. 1986 Pediatr. Res. pmid:3703623
Sauvant D et al. [The relationship between udder secretion and the content of blood energy nutriments and nitrogen in the goat at the onset of lactation]. 1986 Reprod Nutr Dev pmid:3726269
Ally AI et al. Trimethyltin as a selective adrenal chemosympatholytic agent in vivo: effect precedes both clinical and histopathological evidence of toxicity. 1986 Toxicology pmid:3726895
Cherel Y et al. Ambient temperature and ketone body plasma concentration in fasting geese. 1986 Pflugers Arch. pmid:3737378
Wicklmayr M et al. Inhibition of muscular triglyceride lipolysis by ketone bodies: a mechanism for energy-preservation in starvation. 1986 Horm. Metab. Res. pmid:3744294
Derr RF and Derr MI Separation of the tremorous and muscular rigidity components of the ethanol withdrawal syndrome in the rat. 1986 Physiol. Behav. pmid:3786490
Freinkel N et al. The 1986 McCollum award lecture. Fuel-mediated teratogenesis during early organogenesis: the effects of increased concentrations of glucose, ketones, or somatomedin inhibitor during rat embryo culture. 1986 Am. J. Clin. Nutr. pmid:3788845
Thomas DJ et al. Insulin infusion (GIK) in the treatment of type 2 (non-insulin dependent) diabetes during the perioperative period. 1986 Br J Surg pmid:3790919
Metcalfe HK et al. Carrier-mediated efflux of ketone bodies in isolated rat hepatocytes. 1986 Clin. Sci. pmid:3791876
Loy SF et al. Effects of 24-hour fast on cycling endurance time at two different intensities. 1986 J. Appl. Physiol. pmid:3745057
Van der Plas J et al. Effect of coupling of 2-nor-2-formylpyridoxal 5'-phosphate to stroma-free hemoglobin on oxygen affinity and tissue oxygenation. Studies in the isolated perfused rat liver under conditions of normoxia and stagnant hypoxia. 1986 J. Lab. Clin. Med. pmid:3746098
Sapolsky RM Glucocorticoid toxicity in the hippocampus: reversal by supplementation with brain fuels. 1986 J. Neurosci. pmid:3746406
Lammerant J et al. In vivo effect of the D-(-) isomer or natural form of 3-hydroxybutyrate on initial release of lactate dehydrogenase from the acutely ischaemic myocardium. 1986 J. Mol. Cell. Cardiol. pmid:3746923
Middleton B et al. 3-Ketothiolase deficiency. 1986 Eur. J. Pediatr. pmid:3709573
Nakai T et al. Decreased ketonaemia in the monosodium glutamate-induced obese rats. 1986 Life Sci. pmid:3713435
Scharrer E and Langhans W Control of food intake by fatty acid oxidation. 1986 Am. J. Physiol. pmid:3717372
Fernández E and Medina JM Lactate utilization by the neonatal rat brain in vitro. Competition with glucose and 3-hydroxybutyrate. 1986 Biochem. J. pmid:3718483
Young JC et al. Effects of oral hypoglycemic agent methylpalmoxirate on exercise capacity of streptozocin diabetic rats. 1986 Diabetes pmid:3721061
London ED et al. Effects of fasting on ketone body concentrations in healthy men of different ages. 1986 J Gerontol pmid:3489030
Tuchman M et al. Clinical and laboratory observations in a child with hepatic phosphorylase kinase deficiency. 1986 Metab. Clin. Exp. pmid:3459948
Miller AL Regional glucose and beta-hydroxybutyrate use by developing rat brain. 1986 Metab Brain Dis pmid:3508236
Shimahara Y and Isselhard W Evaluation of a short-time, oxygen carrier-free perfusion model in rat liver: mitochondrial energy metabolism and insulin effect. 1986 J. Surg. Res. pmid:3510336
Hoelzer DR et al. Glucoregulation during exercise: hypoglycemia is prevented by redundant glucoregulatory systems, sympathochromaffin activation, and changes in islet hormone secretion. 1986 J. Clin. Invest. pmid:3511090
Zuniga-Guajardo S et al. Effects of massive obesity on insulin sensitivity and insulin clearance and the metabolic response to insulin as assessed by the euglycemic clamp technique. 1986 Metab. Clin. Exp. pmid:3512959
Cersosimo E et al. Glutamine blocks lipolysis and ketogenesis of fasting. 1986 Am. J. Physiol. pmid:3513612
Pallikarakis N et al. Remarkable metabolic availability of oral glucose during long-duration exercise in humans. 1986 J. Appl. Physiol. pmid:3514570
Ravussin E et al. Effect of elevated FFA on carbohydrate and lipid oxidation during prolonged exercise in humans. 1986 J. Appl. Physiol. pmid:3514572
Guder WG et al. Metabolic fuels along the nephron: pathways and intracellular mechanisms of interaction. 1986 Kidney Int. pmid:3515013
Albisser AM et al. Intermediary metabolism in diabetic dogs treated with pancreatic autotransplants and insulin pumps. 1986 Metab. Clin. Exp. pmid:3515120
Féry F and Balasse EO Response of ketone body metabolism to exercise during transition from postabsorptive to fasted state. 1986 Am. J. Physiol. pmid:3518484
Christensen CK et al. Effect of 3-hydroxybutyrate infusion on urinary protein excretion in healthy man. 1986 Scand. J. Clin. Lab. Invest. pmid:3520791
Rodriguez J et al. Carnitine metabolism during fasting in dogs. 1986 Surgery pmid:3520914
Heitmann RN and Fernandez JM Autoregulation of alimentary and hepatic ketogenesis in sheep. 1986 J. Dairy Sci. pmid:3522682
Tani T et al. Short-term changes in blood ketone body ratios in the phase immediately after hepatic artery embolization: their clinical significance. 1986 Am. J. Med. Sci. pmid:3004212
Nomura M et al. The metabolic and hormonal adaptations of normal dogs to long-term exogenous sulfated insulin infusions. 1986 Metab. Clin. Exp. pmid:3531758
Schweiger U et al. Effects of carbohydrate and protein meals on plasma large neutral amino acids, glucose, and insulin plasma levels of anorectic patients. 1986 Metab. Clin. Exp. pmid:3531760
Press M et al. Effect of insulin on growth hormone-induced metabolic derangements in diabetes. 1986 Metab. Clin. Exp. pmid:3531761
Gillmer MD et al. Low energy diets in the treatment of gestational diabetes. 1986 Acta Endocrinol Suppl (Copenh) pmid:3532669
Seaton TB et al. Thermic effect of medium-chain and long-chain triglycerides in man. 1986 Am. J. Clin. Nutr. pmid:3532757
Oomura Y Feeding regulation by endogenous sugar acids through hypothalamic chemosensitive neurons. 1986 Brain Res. Bull. pmid:3536001
Carlin JI et al. Carnitine metabolism during prolonged exercise and recovery in humans. 1986 J. Appl. Physiol. pmid:3536833
Dohm GL et al. Metabolic responses to exercise after fasting. 1986 J. Appl. Physiol. pmid:3536834
Zuniga-Guajardo S et al. Changes in insulin sensitivity and clearance in anorexia nervosa. 1986 Metab. Clin. Exp. pmid:3537630
Lowell BB et al. Regulation of myofibrillar protein degradation in rat skeletal muscle during brief and prolonged starvation. 1986 Metab. Clin. Exp. pmid:3537631
Melegh B et al. Uptake of beta-hydroxybutyrate, acetoacetate and glucose by the forearm of the newborn infant. 1986 Acta Paediatr Hung pmid:3593582
Davies AO Effects of endogenous redox-active compounds on coupling of human beta 2-adrenergic receptors. 1986 Am. J. Med. Sci. pmid:3022589
Gray RS et al. Reversal of insulin resistance in type 1 diabetes following initiation of insulin treatment. 1986 Diabet. Med. pmid:2951129
Hawkins RA et al. Regional ketone body utilization by rat brain in starvation and diabetes. 1986 Am. J. Physiol. pmid:2937307
Gil J et al. Effects of diabetes on fructose 2, 6-P2, glucose 1, 6-P2 and 6-phosphofructo 2-kinase in rat liver. 1986 Biochem. Biophys. Res. Commun. pmid:3010981
Stappenbeck R et al. Perchloric acid interference in enzymatic-fluorimetric-continuous-flow assay methods for measuring glucose, lactate, pyruvate, alanine, glycerol, and 3-hydroxybutyrate in blood. 1986 Clin. Chem. pmid:3011312
Helms RA et al. Enhanced lipid utilization in infants receiving oral L-carnitine during long-term parenteral nutrition. 1986 J. Pediatr. pmid:3097293
McKenna MC et al. Competition of glycerol with other oxidizable substrates in rat brain. 1986 Biochem. J. pmid:3099749
Miodovnik M et al. Effect of maternal hyperketonemia in hyperglycemic pregnant ewes and their fetuses. 1986 Am. J. Obstet. Gynecol. pmid:3946526
Lee SY et al. Effect of hyperthermia on the lactic acid and beta-hydroxybutyric acid content in tumour. 1986 Apr-Jun Int J Hyperthermia pmid:3794417
Cederblad G and Svenningsen N Plasma carnitine and breast milk carnitine intake in premature infants. 1986 Jul-Aug J. Pediatr. Gastroenterol. Nutr. pmid:3735012
Scheen AJ et al. Anti-insulin antibodies and metabolic deterioration after interruption of continuous subcutaneous insulin infusion. 1986 Nov-Dec Diabetes Care pmid:3803158
Combs DJ et al. Glycolytic inhibition by 2-deoxyglucose reduces hyperglycemia-associated mortality and morbidity in the ischemic rat. 1986 Sep-Oct Stroke pmid:3764973
Bougneres PF and Ferre P Study of ketone body kinetics in children by a combined perfusion of 13C and 2H3 tracers. 1987 Am. J. Physiol. pmid:3688221
Cobelli C et al. Models to interpret kinetic data in stable isotope tracer studies. 1987 Am. J. Physiol. pmid:3688225
Lincoln BC et al. Metabolism of S-3-hydroxybutyrate in the perfused rat liver. 1987 Arch. Biochem. Biophys. pmid:3688882
Kruszynska YT and Sherratt HS Glucose kinetics during acute and chronic treatment of rats with 2[6(4-chloro-phenoxy)hexyl]oxirane-2-carboxylate, etomoxir. 1987 Biochem. Pharmacol. pmid:3689429
Bray GA et al. Brain uptake of ketones in rats with differing susceptibility to dietary obesity. 1987 Metab. Clin. Exp. pmid:3796295
Hunter ES and Sadler TW D-(-)-beta-hydroxybutyrate-induced effects on mouse embryos in vitro. 1987 Teratology pmid:3424210
Brundin T et al. Blood flow, substrate utilization and heat generation in tissues drained by the azygos vein in man. 1987 Clin Physiol pmid:3427881
Latruffe N Transport of D-beta-hydroxybutyrate across rat liver mitochondrial membranes. 1987 Comp. Biochem. Physiol., B pmid:3427918
Carlin JI et al. The effects of post-exercise glucose and alanine ingestion on plasma carnitine and ketosis in humans. 1987 J. Physiol. (Lond.) pmid:3443938
Vilaró S et al. Chronic and acute ethanol impair the in vivo glucose uptake by lactating rat mammary gland. 1987 Biosci. Rep. pmid:3447639
Lövgren B and Hellstrand P Functional role of aerobic glycolysis in rat portal vein. 1987 Acta Physiol. Scand. pmid:3577809
Dynnik VV et al. Stoichiometric traps in the tricarboxylic acid cycle. I. Self-inhibition and triggering phenomena. 1987 Biochem. Int. pmid:3579962
Park GD et al. Sustained reductions in oxipurinol renal clearance during a restricted diet. 1987 Clin. Pharmacol. Ther. pmid:3581647
Koch DD and Feldbruegge DH Optimized kinetic method for automated determination of beta-hydroxybutyrate. 1987 Clin. Chem. pmid:3665027
Kimura RE Glutamine oxidation by developing rat small intestine. 1987 Pediatr. Res. pmid:3103088
Hallas J The association between calcium and acetoacetate, 3-hydroxybutyrate, pyruvate and lactate as determined by potentiometry. Determination of concentrational complexity constants in watery solutions at physiological conditions. 1987 Scand. J. Clin. Lab. Invest. pmid:3672031
Kotas AM and Prince AK High-affinity uptake of choline, a marker for cholinergic nerve terminals, is not specific in developing rat brain. 1987 Brain Res. pmid:3676836
Matsuo M et al. Urinary evidence of disturbance of mitochondrial respiratory chain in Reye syndrome. 1987 J. Pediatr. pmid:3598782
Sanjak M et al. Physiologic and metabolic response to progressive and prolonged exercise in amyotrophic lateral sclerosis. 1987 Neurology pmid:3601086
Sann L et al. Ketogenesis in hypoglycemic neonates. Carnitine and dicarboxylic acids in neonatal hypoglycemia. 1987 Biol. Neonate pmid:3651517
Noguchi M et al. Acute responses of blood ketone body ratio following devascularization and revascularization of rabbit liver. 1987 Eur Surg Res pmid:3653157
Pethick DW et al. Non-esterified long-chain fatty acid metabolism in fed sheep at rest and during exercise. 1987 Aust. J. Biol. Sci. pmid:3662970
Nosadini R et al. Glucose and ketone body turnover in carnitine-palmitoyl-transferase deficiency. 1987 Metab. Clin. Exp. pmid:3626864
Lai JC and Sheu KF The effect of 2-oxoglutarate or 3-hydroxybutyrate on pyruvate dehydrogenase complex in isolated cerebrocortical mitochondria. 1987 Neurochem. Res. pmid:3627360
Greig C et al. The effect of oral supplementation with L-carnitine on maximum and submaximum exercise capacity. 1987 Eur J Appl Physiol Occup Physiol pmid:3305002
De Feo P et al. The pancreatic-adrenocortical-pituitary clamp technique for study of counterregulation in humans. 1987 Am. J. Physiol. pmid:2882686
Kaminsky YG and Kosenko EA Different effects of 2,4-dinitrophenol on rat liver mitochondrial oxidation of various substrates: succinate and glutamate vs 3-hydroxybutyrate and glycerol 3-phosphate. 1987 Int. J. Biochem. pmid:2883037
Tullson PC and Aprille JR Regulation of mitochondrial adenine nucleotide content in newborn rabbit liver. 1987 Am. J. Physiol. pmid:2891302
Aarsen RS et al. Long-acting somatostatin analogue (Sandostatin) reduces late night insulinopenic ketogenesis in diabetic teenagers. 1987 Acta Endocrinol Suppl (Copenh) pmid:2892337
Hunter ES et al. A potential mechanism of DL-beta-hydroxybutyrate-induced malformations in mouse embryos. 1987 Am. J. Physiol. pmid:3111272
Okuda Y et al. Age-related change in ketone body metabolism: diminished glucagon effect on ketogenesis in adult rats. 1987 Endocrinology pmid:3032575
Singh BM et al. Metabolic effects of combined oral contraceptive preparations. 1987 Contraception pmid:3128428