(r)-3-hydroxybutanoic acid
(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.
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Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bougneres PF and Ferre P | Study of ketone body kinetics in children by a combined perfusion of 13C and 2H3 tracers. | 1987 | Am. J. Physiol. | pmid:3688221 |
| Cobelli C et al. | Models to interpret kinetic data in stable isotope tracer studies. | 1987 | Am. J. Physiol. | pmid:3688225 |
| Bougnères PF et al. | Stable isotope determination of plasma lactate conversion into glucose in fasting infants. | 1995 | Am. J. Physiol. | pmid:7733264 |
| Rössle C et al. | Medium-chain triglycerides induce alterations in carnitine metabolism. | 1990 | Am. J. Physiol. | pmid:2360627 |
| Harris RB and Martin RJ | Specific depletion of body fat in parabiotic partners of tube-fed obese rats. | 1984 | Am. J. Physiol. | pmid:6431831 |
| Marker JC et al. | Reduced epinephrine clearance and glycemic sensitivity to epinephrine in older individuals. | 1998 | Am. J. Physiol. | pmid:9814995 |
| Miles JM et al. | A dual-isotope technique for determination of in vivo ketone body kinetics. | 1986 | Am. J. Physiol. | pmid:3526920 |
| Davis TA et al. | Response of muscle protein synthesis to fasting in suckling and weaned rats. | 1991 | Am. J. Physiol. | pmid:1721504 |
| Beattie MA and Winder WW | Mechanism of training-induced attenuation of postexercise ketosis. | 1984 | Am. J. Physiol. | pmid:6093602 |
| Shaw JH and Wolfe RR | Influence of beta-hydroxybutyrate infusion on glucose and free fatty acid metabolism in dogs. | 1984 | Am. J. Physiol. | pmid:6095672 |
| Castellini MA and Costa DP | Relationships between plasma ketones and fasting duration in neonatal elephant seals. | 1990 | Am. J. Physiol. | pmid:2240269 |
| Uchida S and Endou H | Substrate specificity to maintain cellular ATP along the mouse nephron. | 1988 | Am. J. Physiol. | pmid:2847554 |
| Malaisse WJ et al. | Ketone bodies and islet function: 45Ca handling, insulin synthesis, and release. | 1990 | Am. J. Physiol. | pmid:2196820 |
| Tullson PC and Aprille JR | Regulation of mitochondrial adenine nucleotide content in newborn rabbit liver. | 1987 | Am. J. Physiol. | pmid:2891302 |
| Malaisse WJ et al. | Ketone bodies and islet function: 86Rb handling and metabolic data. | 1990 | Am. J. Physiol. | pmid:2196821 |
| Loucks AB and Verdun M | Slow restoration of LH pulsatility by refeeding in energetically disrupted women. | 1998 | Am. J. Physiol. | pmid:9756553 |
| Monti LD et al. | Metabolic and endothelial effects of trimetazidine on forearm skeletal muscle in patients with type 2 diabetes and ischemic cardiomyopathy. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16174656 |
| Pelletier A and Coderre L | Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17227964 |
| Chu CA et al. | Effects of free fatty acids on hepatic glycogenolysis and gluconeogenesis in conscious dogs. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11788373 |
| Galassetti P et al. | Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11350772 |
| McGregor VP et al. | Elevated endogenous cortisol reduces autonomic neuroendocrine and symptom responses to subsequent hypoglycemia. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:11882496 |
| Everett-Grueter C et al. | The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16608886 |
| El Midaoui A et al. | Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15774485 |
| Vannucci SJ and Simpson IA | Developmental switch in brain nutrient transporter expression in the rat. | 2003 | Am. J. Physiol. Endocrinol. Metab. | pmid:14534079 |
| Ravikumar B et al. | Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15572652 |
| Blomqvist G et al. | Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:12067838 |
| El Midaoui A et al. | Physical training reverses the increased activity of the hepatic ketone body synthesis pathway in chronically diabetic rats. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16403781 |
| Hodson L et al. | Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20628024 |
| Stannard SR et al. | Fasting for 72 h increases intramyocellular lipid content in nondiabetic, physically fit men. | 2002 | Am. J. Physiol. Endocrinol. Metab. | pmid:12388154 |
| Yamada T et al. | {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20516259 |
| Song H et al. | Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20179248 |
| Takehiro M et al. | Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents. | 2005 | Am. J. Physiol. Endocrinol. Metab. | pmid:15479955 |
| Zhang D et al. | Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:20959534 |
| Chalhoub E et al. | A computer model of gluconeogenesis and lipid metabolism in the perfused liver. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17911349 |
| Bielohuby M et al. | Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:20943751 |
| Puchowicz MA et al. | Diet-induced ketosis increases capillary density without altered blood flow in rat brain. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17284577 |
| Malkova D et al. | Prior exercise and postprandial substrate extraction across the human leg. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11052956 |
| Connolly CC et al. | Alterations in basal glucose metabolism during late pregnancy in the conscious dog. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11052973 |
| Jackson PA et al. | Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:11093911 |
| Tardif A et al. | Chronic exposure to beta-hydroxybutyrate impairs insulin action in primary cultures of adult cardiomyocytes. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11701435 |
| Jensen MD et al. | Lipid metabolism during fasting. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11551856 |
| St Amand TA et al. | Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913026 |
| Stallknecht B et al. | Effect of training on insulin sensitivity of glucose uptake and lipolysis in human adipose tissue. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913038 |
| Chu CA et al. | The direct effects of catecholamines on hepatic glucose production occur via alpha(1)- and beta(2)-receptors in the dog. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10913048 |
| Plaisance EP et al. | Niacin stimulates adiponectin secretion through the GPR109A receptor. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19141678 |
| Dasarathy S et al. | Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19571235 |
| Cremin JD et al. | Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12637251 |
| Zou Z et al. | dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12384475 |
| Stanley WC et al. | beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12969881 |
| Linke A et al. | Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12915387 |
| White RL and Wittenberg BA | Mitochondrial NAD(P)H, ADP, oxidative phosphorylation, and contraction in isolated heart cells. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11009472 |
| Bigrigg JK et al. | Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19625693 |
| Bernard SF et al. | Blockade of fatty acid oxidation mimics phase II-phase III transition in a fasting bird, the king penguin. | 2002 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12069939 |
| Bernard SF et al. | Lipolytic and metabolic response to glucagon in fasting king penguins: phase II vs. phase III. | 2003 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12388477 |
| Becskei C et al. | Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20538900 |
| Connolly CC et al. | Hepatic and muscle insulin action during late pregnancy in the dog. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:16973936 |
| Luci S et al. | Clofibrate causes an upregulation of PPAR-{alpha} target genes but does not alter expression of SREBP target genes in liver and adipose tissue of pigs. | 2007 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:17363680 |
| DÃaz-Muñoz M et al. | Anticipatory changes in liver metabolism and entrainment of insulin, glucagon, and corticosterone in food-restricted rats. | 2000 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11080068 |
| Verrier D et al. | Physiological response to extreme fasting in subantarctic fur seal (Arctocephalus tropicalis) pups: metabolic rates, energy reserve utilization, and water fluxes. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19776248 |
| Andrews MT et al. | Adaptive mechanisms regulate preferred utilization of ketones in the heart and brain of a hibernating mammal during arousal from torpor. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19052316 |
| Li M et al. | GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy. | 2013 | Am. J. Physiol. Renal Physiol. | pmid:23467425 |
| Aromolaran AS et al. | Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17344311 |
| MacDonald MJ et al. | Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion. | 2008 | Am. J. Physiol., Cell Physiol. | pmid:18160486 |
| Mori K et al. | Insulinopenia as a risk factor in hepatectomy and its resolution by intraportal insulin administration. | 1991 | Am. J. Surg. | pmid:2063969 |
| Sasi P et al. | Metabolic acidosis and other determinants of hemoglobin-oxygen dissociation in severe childhood Plasmodium falciparum malaria. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17690396 |
| Lacetera N et al. | Effects of nonesterified fatty acids and beta-hydroxybutyrate on functions of mononuclear cells obtained from ewes. | 2002 | Am. J. Vet. Res. | pmid:11911577 |
| Oikawa S et al. | Decreased serum apolipoprotein B-100 and A-I concentrations in cows with ketosis and left displacement of the abomasum. | 1997 | Am. J. Vet. Res. | pmid:9028472 |
| Herdt TH et al. | Blood concentrations of beta hydroxybutyrate in clinically normal Holstein-Friesian herds and in those with a high prevalence of clinical ketosis. | 1981 | Am. J. Vet. Res. | pmid:7271015 |
| Herdt TH et al. | Influence of ration composition and energy balance on blood beta-hydroxybutyrate (ketone) and plasma glucose concentrations of dairy cows in early lactation. | 1981 | Am. J. Vet. Res. | pmid:7271038 |
| Targowski SP et al. | Suppression of mitogenic response of bovine lymphocytes during experimental ketosis in calves. | 1985 | Am. J. Vet. Res. | pmid:4026018 |
| Cebra CK and Tornquist SJ | Assessment of the effects of epinephrine and insulin on plasma and serum biochemical variables in llamas and alpacas. | 2004 | Am. J. Vet. Res. | pmid:15631035 |
| de Graaf-Roelfsema E et al. | Effects of short- and long-term recombinant equine growth hormone and short-term hydrocortisone administration on tissue sensitivity to insulin in horses. | 2005 | Am. J. Vet. Res. | pmid:16334949 |
| Gossett KA et al. | Contribution of whole blood L-lactate, pyruvate, D-lactate, acetoacetate, and 3-hydroxybutyrate concentrations to the plasma anion gap in horses with intestinal disorders. | 1987 | Am. J. Vet. Res. | pmid:3826846 |
| Dufva GS et al. | Effect of dietary niacin supplementation on phlorhizin and 1,3-butanediol-induced ketonemia and hypoglycemia in steers. | 1984 | Am. J. Vet. Res. | pmid:6497141 |
| Cebra CK et al. | Effects of hydrocortisone on substrates of energy metabolism in alpacas. | 2002 | Am. J. Vet. Res. | pmid:12224859 |
| Fallin CW and Christopher MM | In vitro effect of ketones and hyperglycemia on feline hemoglobin oxidation and D- and L-lactate production. | 1996 | Am. J. Vet. Res. | pmid:8712507 |
| Pravettoni D et al. | Insulin resistance and abomasal motility disorders in cows detected by use of abomasoduodenal electromyography after surgical correction of left displaced abomasum. | 2004 | Am. J. Vet. Res. | pmid:15524316 |
| Reist M et al. | Use of threshold serum and milk ketone concentrations to identify risk for ketosis and endometritis in high-yielding dairy cows. | 2003 | Am. J. Vet. Res. | pmid:12602588 |
| Eicher R et al. | Effect of cow-specific factors and feeding frequency of concentrate on diurnal variations of blood metabolites in dairy cows. | 1999 | Am. J. Vet. Res. | pmid:10622157 |
| Hornig KJ et al. | Evaluation of a point-of-care glucose and β-hydroxybutyrate meter operated in various environmental conditions in prepartum and postpartum sheep. | 2013 | Am. J. Vet. Res. | pmid:23879842 |
| Wagner SA and Schimek DE | Evaluation of the effect of bolus administration of 50% dextrose solution on measures of electrolyte and energy balance in postpartum dairy cows. | 2010 | Am. J. Vet. Res. | pmid:20807148 |
| Geishauser T et al. | Evaluation of aspartate transaminase activity and beta-hydroxybutyrate concentration in blood as tests for prediction of left displaced abomasum in dairy cows. | 1997 | Am. J. Vet. Res. | pmid:9361881 |
| Westermann CM et al. | Plasma acylcarnitine and fatty acid profiles during exercise and training in Standardbreds. | 2008 | Am. J. Vet. Res. | pmid:18980429 |
| Lacetera N et al. | Effects of subclinical pregnancy toxemia on immune responses in sheep. | 2001 | Am. J. Vet. Res. | pmid:11453474 |
| Tornquist SJ et al. | Metabolic changes and induction of hepatic lipidosis during feed restriction in llamas. | 2001 | Am. J. Vet. Res. | pmid:11453484 |
| Lei J et al. | Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells. | 2012 | Amino Acids | pmid:22543725 |
| Reyes-Toso CF et al. | Effect of melatonin treatment on oxygen consumption by rat liver mitochondria. | 2006 | Amino Acids | pmid:16554975 |
| López Siguero JP et al. | [Blood glucose and ketone monitoring in type 1 diabetic patients in the controlled environment of a summer camp]. | 2007 | An Pediatr (Barc) | pmid:17430716 |
| Scrutton MJ et al. | Eating in labour. A randomised controlled trial assessing the risks and benefits. | 1999 | Anaesthesia | pmid:10455830 |
| Altemeyer KH et al. | [The stress reaction in knee operations under continuous peridural anesthesia in comparison with neuroleptanalgesia]. | 1983 | Anaesthesist | pmid:6346939 |
| Tsutsui H et al. | Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS. | 2012 | Anal Bioanal Chem | pmid:22895741 |
| Shimomura T et al. | A novel, disposable, screen-printed amperometric biosensor for ketone 3-β-hydroxybutyrate fabricated using a 3-β-hydroxybutyrate dehydrogenase-mesoporous silica conjugate. | 2013 | Anal Bioanal Chem | pmid:23096941 |
| Lam le H et al. | Assay of angiotensin I-converting enzyme-inhibiting activity based on the detection of 3-hydroxybutyrate with water-soluble tetrazolium salt. | 2008 | Anal Sci | pmid:18689950 |
| Kiba N et al. | Simultaneous determination of D-glucose and 3-hydroxybutyrate by chemiluminescence detection with immobilized enzymes in a flow injection system. | 2003 | Anal Sci | pmid:12945679 |
| Yamai K et al. | Acetone concentration in gas emanating from tails of diabetic rats. | 2012 | Anal Sci | pmid:22687932 |
| Miles JM et al. | Determination of ketone body turnover in vivo with stable isotopes, utilizing gas chromatography/mass spectrometry. | 1984 | Anal. Biochem. | pmid:6496922 |
| Sener A and Malaisse WJ | A sensitive radioisotopic method for the measurement of NAD(P)H: its application to the assay of metabolites and enzymatic activities. | 1990 | Anal. Biochem. | pmid:2363494 |
| Des Rosiers C et al. | Interference of 3-hydroxyisobutyrate with measurements of ketone body concentration and isotopic enrichment by gas chromatography-mass spectrometry. | 1988 | Anal. Biochem. | pmid:3189805 |
| Lam le H et al. | Assay of angiotensin I-converting enzyme-inhibiting activity based on the detection of 3-hydroxybutyric acid. | 2007 | Anal. Biochem. | pmid:17386920 |
| Persson M et al. | Measurement of plasma acetate kinetics using high-performance liquid chromatography. | 1991 | Anal. Biochem. | pmid:1789417 |