(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Alzheimer Disease D000544 76 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cholestasis D002779 23 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Hypoglycemia D007003 13 associated lipids
Metabolic Diseases D008659 12 associated lipids
Starvation D013217 47 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Dwarfism, Pituitary D004393 3 associated lipids
Glycosuria D006029 10 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Birth Weight D001724 23 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Alkalosis D000471 3 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Bougneres PF and Ferre P Study of ketone body kinetics in children by a combined perfusion of 13C and 2H3 tracers. 1987 Am. J. Physiol. pmid:3688221
Cobelli C et al. Models to interpret kinetic data in stable isotope tracer studies. 1987 Am. J. Physiol. pmid:3688225
Bougnères PF et al. Stable isotope determination of plasma lactate conversion into glucose in fasting infants. 1995 Am. J. Physiol. pmid:7733264
Rössle C et al. Medium-chain triglycerides induce alterations in carnitine metabolism. 1990 Am. J. Physiol. pmid:2360627
Harris RB and Martin RJ Specific depletion of body fat in parabiotic partners of tube-fed obese rats. 1984 Am. J. Physiol. pmid:6431831
Marker JC et al. Reduced epinephrine clearance and glycemic sensitivity to epinephrine in older individuals. 1998 Am. J. Physiol. pmid:9814995
Miles JM et al. A dual-isotope technique for determination of in vivo ketone body kinetics. 1986 Am. J. Physiol. pmid:3526920
Davis TA et al. Response of muscle protein synthesis to fasting in suckling and weaned rats. 1991 Am. J. Physiol. pmid:1721504
Beattie MA and Winder WW Mechanism of training-induced attenuation of postexercise ketosis. 1984 Am. J. Physiol. pmid:6093602
Shaw JH and Wolfe RR Influence of beta-hydroxybutyrate infusion on glucose and free fatty acid metabolism in dogs. 1984 Am. J. Physiol. pmid:6095672
Castellini MA and Costa DP Relationships between plasma ketones and fasting duration in neonatal elephant seals. 1990 Am. J. Physiol. pmid:2240269
Uchida S and Endou H Substrate specificity to maintain cellular ATP along the mouse nephron. 1988 Am. J. Physiol. pmid:2847554
Malaisse WJ et al. Ketone bodies and islet function: 45Ca handling, insulin synthesis, and release. 1990 Am. J. Physiol. pmid:2196820
Tullson PC and Aprille JR Regulation of mitochondrial adenine nucleotide content in newborn rabbit liver. 1987 Am. J. Physiol. pmid:2891302
Malaisse WJ et al. Ketone bodies and islet function: 86Rb handling and metabolic data. 1990 Am. J. Physiol. pmid:2196821
Loucks AB and Verdun M Slow restoration of LH pulsatility by refeeding in energetically disrupted women. 1998 Am. J. Physiol. pmid:9756553
Monti LD et al. Metabolic and endothelial effects of trimetazidine on forearm skeletal muscle in patients with type 2 diabetes and ischemic cardiomyopathy. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16174656
Pelletier A and Coderre L Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17227964
Chu CA et al. Effects of free fatty acids on hepatic glycogenolysis and gluconeogenesis in conscious dogs. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11788373
Galassetti P et al. Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11350772
McGregor VP et al. Elevated endogenous cortisol reduces autonomic neuroendocrine and symptom responses to subsequent hypoglycemia. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11882496
Everett-Grueter C et al. The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16608886
El Midaoui A et al. Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15774485
Vannucci SJ and Simpson IA Developmental switch in brain nutrient transporter expression in the rat. 2003 Am. J. Physiol. Endocrinol. Metab. pmid:14534079
Ravikumar B et al. Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15572652
Blomqvist G et al. Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:12067838
El Midaoui A et al. Physical training reverses the increased activity of the hepatic ketone body synthesis pathway in chronically diabetic rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16403781
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Stannard SR et al. Fasting for 72 h increases intramyocellular lipid content in nondiabetic, physically fit men. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:12388154
Yamada T et al. {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20516259
Song H et al. Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20179248
Takehiro M et al. Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15479955
Zhang D et al. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959534
Chalhoub E et al. A computer model of gluconeogenesis and lipid metabolism in the perfused liver. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17911349
Bielohuby M et al. Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20943751
Puchowicz MA et al. Diet-induced ketosis increases capillary density without altered blood flow in rat brain. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17284577
Malkova D et al. Prior exercise and postprandial substrate extraction across the human leg. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052956
Connolly CC et al. Alterations in basal glucose metabolism during late pregnancy in the conscious dog. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052973
Jackson PA et al. Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11093911
Tardif A et al. Chronic exposure to beta-hydroxybutyrate impairs insulin action in primary cultures of adult cardiomyocytes. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11701435
Jensen MD et al. Lipid metabolism during fasting. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11551856
St Amand TA et al. Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913026
Stallknecht B et al. Effect of training on insulin sensitivity of glucose uptake and lipolysis in human adipose tissue. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913038
Chu CA et al. The direct effects of catecholamines on hepatic glucose production occur via alpha(1)- and beta(2)-receptors in the dog. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913048
Plaisance EP et al. Niacin stimulates adiponectin secretion through the GPR109A receptor. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19141678
Dasarathy S et al. Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19571235
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Zou Z et al. dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:12384475
Stanley WC et al. beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12969881
Linke A et al. Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12915387