(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Pregnancy Complications D011248 19 associated lipids
Cat Diseases D002371 12 associated lipids
Puerperal Disorders D011644 4 associated lipids
Weight Loss D015431 56 associated lipids
Critical Illness D016638 13 associated lipids
Anorexia D000855 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Thinness D013851 11 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Obesity, Morbid D009767 8 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Alkalosis, Respiratory D000472 4 associated lipids
Glycogen Storage Disease Type I D005953 4 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Lipid Metabolism Disorders D052439 3 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Cardiac Output, Low D002303 2 associated lipids
Pyruvate Dehydrogenase Complex Deficiency Disease D015325 3 associated lipids
Pyruvate Metabolism, Inborn Errors D015323 3 associated lipids
Short Bowel Syndrome D012778 3 associated lipids
Aortopulmonary Septal Defect D001028 1 associated lipids
Thyrotoxicosis D013971 3 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Muscle Rigidity D009127 4 associated lipids
Bulimia D002032 3 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Fructose-1,6-Diphosphatase Deficiency D015319 1 associated lipids
Syndrome D013577 4 associated lipids
Trypanosomiasis, African D014353 5 associated lipids
Liver Failure D017093 5 associated lipids
Hepatitis, Alcoholic D006519 5 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Spinal Muscular Atrophies of Childhood D014897 1 associated lipids
Lipoma D008067 1 associated lipids
Hyperandrogenism D017588 5 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Epilepsy, Reflex D020195 5 associated lipids
Adenocarcinoma, Clear Cell D018262 1 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Encephalopathy, Bovine Spongiform D016643 2 associated lipids
Status Epilepticus D013226 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Fetal Macrosomia D005320 3 associated lipids
HIV Wasting Syndrome D019247 3 associated lipids
Endometritis D004716 6 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Goldstein RE et al. Effects of chronic elevation in plasma cortisol on hepatic carbohydrate metabolism. 1993 Am. J. Physiol. pmid:8430780
Rössle C et al. Medium-chain triglycerides induce alterations in carnitine metabolism. 1990 Am. J. Physiol. pmid:2360627
Turcotte LP et al. Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans. 1992 Am. J. Physiol. pmid:1319676
Féry F and Balasse EO Response of ketone body metabolism to exercise during transition from postabsorptive to fasted state. 1986 Am. J. Physiol. pmid:3518484
De Feo P et al. Evidence against important catecholamine compensation for absent glucagon counterregulation. 1991 Am. J. Physiol. pmid:1996624
Shambaugh GE et al. Fetal fuels. VII. Ketone bodies inhibit synthesis of purines in fetal rat brain. 1984 Am. J. Physiol. pmid:6742185
Bougnères PF et al. Medium-chain fatty acids increase glucose production in normal and low birth weight newborns. 1989 Am. J. Physiol. pmid:2719106
Lundgren F et al. Substrate exchange in human limb muscle during exercise at reduced blood flow. 1988 Am. J. Physiol. pmid:3142276
Winder WW et al. Endurance training attenuates stress hormone responses to exercise in fasted rats. 1982 Am. J. Physiol. pmid:6283921
Goodman MN and del Pilar Gomez M Decreased myofibrillar proteolysis after refeeding requires dietary protein or amino acids. 1987 Am. J. Physiol. pmid:3300365
Féry F et al. Role of fat-derived substrates in the regulation of gluconeogenesis during fasting. 1996 Am. J. Physiol. pmid:8967471
Heller SR and Cryer PE Hypoinsulinemia is not critical to glucose recovery from hypoglycemia in humans. 1991 Am. J. Physiol. pmid:1858873
Malaisse WJ et al. Ketone bodies and islet function: 45Ca handling, insulin synthesis, and release. 1990 Am. J. Physiol. pmid:2196820
Malaisse WJ et al. Ketone bodies and islet function: 86Rb handling and metabolic data. 1990 Am. J. Physiol. pmid:2196821
Nosadini R et al. Acetoacetate and 3-hydroxybutyrate kinetics in obese and insulin-dependent diabetic humans. 1985 Am. J. Physiol. pmid:3922234
Geary N et al. Blood metabolites and feeding during postinsulin hypophagia. 1982 Am. J. Physiol. pmid:7051864
Monti LD et al. Metabolic and endothelial effects of trimetazidine on forearm skeletal muscle in patients with type 2 diabetes and ischemic cardiomyopathy. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16174656
Pelletier A and Coderre L Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17227964
Chu CA et al. Effects of free fatty acids on hepatic glycogenolysis and gluconeogenesis in conscious dogs. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11788373
Galassetti P et al. Effects of antecedent prolonged exercise on subsequent counterregulatory responses to hypoglycemia. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11350772
McGregor VP et al. Elevated endogenous cortisol reduces autonomic neuroendocrine and symptom responses to subsequent hypoglycemia. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11882496
Everett-Grueter C et al. The effect of an acute elevation of NEFA concentrations on glucagon-stimulated hepatic glucose output. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16608886
El Midaoui A et al. Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15774485
Vannucci SJ and Simpson IA Developmental switch in brain nutrient transporter expression in the rat. 2003 Am. J. Physiol. Endocrinol. Metab. pmid:14534079
Ravikumar B et al. Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15572652
Blomqvist G et al. Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:12067838
El Midaoui A et al. Physical training reverses the increased activity of the hepatic ketone body synthesis pathway in chronically diabetic rats. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16403781
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Stannard SR et al. Fasting for 72 h increases intramyocellular lipid content in nondiabetic, physically fit men. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:12388154
Yamada T et al. {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20516259
Song H et al. Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20179248
Takehiro M et al. Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents. 2005 Am. J. Physiol. Endocrinol. Metab. pmid:15479955
Zhang D et al. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959534
Chalhoub E et al. A computer model of gluconeogenesis and lipid metabolism in the perfused liver. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17911349
Bielohuby M et al. Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20943751
Puchowicz MA et al. Diet-induced ketosis increases capillary density without altered blood flow in rat brain. 2007 Am. J. Physiol. Endocrinol. Metab. pmid:17284577
Malkova D et al. Prior exercise and postprandial substrate extraction across the human leg. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052956
Connolly CC et al. Alterations in basal glucose metabolism during late pregnancy in the conscious dog. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11052973
Jackson PA et al. Effect of hepatic denervation on the counterregulatory response to insulin-induced hypoglycemia in the dog. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:11093911
Tardif A et al. Chronic exposure to beta-hydroxybutyrate impairs insulin action in primary cultures of adult cardiomyocytes. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11701435
Jensen MD et al. Lipid metabolism during fasting. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11551856
St Amand TA et al. Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913026
Stallknecht B et al. Effect of training on insulin sensitivity of glucose uptake and lipolysis in human adipose tissue. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913038
Chu CA et al. The direct effects of catecholamines on hepatic glucose production occur via alpha(1)- and beta(2)-receptors in the dog. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913048
Plaisance EP et al. Niacin stimulates adiponectin secretion through the GPR109A receptor. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19141678
Dasarathy S et al. Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19571235
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Zou Z et al. dl-3-Hydroxybutyrate administration prevents myocardial damage after coronary occlusion in rat hearts. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:12384475
Stanley WC et al. beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12969881
White RL and Wittenberg BA Mitochondrial NAD(P)H, ADP, oxidative phosphorylation, and contraction in isolated heart cells. 2000 Am. J. Physiol. Heart Circ. Physiol. pmid:11009472