(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Pregnancy Complications D011248 19 associated lipids
Cat Diseases D002371 12 associated lipids
Puerperal Disorders D011644 4 associated lipids
Weight Loss D015431 56 associated lipids
Critical Illness D016638 13 associated lipids
Anorexia D000855 8 associated lipids
Glucose Intolerance D018149 13 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Thinness D013851 11 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Obesity, Morbid D009767 8 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Alkalosis, Respiratory D000472 4 associated lipids
Glycogen Storage Disease Type I D005953 4 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Lipid Metabolism Disorders D052439 3 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Cardiac Output, Low D002303 2 associated lipids
Pyruvate Dehydrogenase Complex Deficiency Disease D015325 3 associated lipids
Pyruvate Metabolism, Inborn Errors D015323 3 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Sarentonglaga B et al. The developmental potential of oocytes is impaired in cattle with liver abnormalities. 2013 J. Reprod. Dev. pmid:23291712
White H et al. Effect of a hypertonic balanced ketone solution on plasma, CSF and brain beta-hydroxybutyrate levels and acid-base status. 2013 Intensive Care Med pmid:23291733
Davidson TL et al. Inter-relationships among diet, obesity and hippocampal-dependent cognitive function. 2013 Neuroscience pmid:23999121
Spoljarić IV et al. In silico optimization and low structured kinetic model of poly[(R)-3-hydroxybutyrate] synthesis by Cupriavidus necator DSM 545 by fed-batch cultivation on glycerol. 2013 J. Biotechnol. pmid:24001933
[Prospective multicenter study on long-term ketogenic diet therapy for intractable childhood epilepsy]. 2013 Zhonghua Er Ke Za Zhi pmid:23927801
Malloy VL et al. Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. 2013 Metab. Clin. Exp. pmid:23928105
Reinke SN et al. 1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy. 2013 J. Proteome Res. pmid:23931672
Fukumori R et al. Ingestion of medium chain fatty acids by lactating dairy cows increases concentrations of plasma ghrelin. 2013 Domest. Anim. Endocrinol. pmid:24209506
Ho CF et al. Ketone bodies upregulate endothelial connexin 43 (Cx43) gap junctions. 2013 Vet. J. pmid:24210276
Wang J et al. Metabolic products of [2-(13) C]ethanol in the rat brain after chronic ethanol exposure. 2013 J. Neurochem. pmid:24033360
Ferguson I and Mullins ME Diagnostic accuracy of fingerstick β-hydroxybutyrate for ketonuria in pregnant women with nausea and vomiting. 2013 Acad Emerg Med pmid:24033684
Mahendran Y et al. Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men. 2013 Diabetes pmid:23557707
Sumithran P et al. Ketosis and appetite-mediating nutrients and hormones after weight loss. 2013 Eur J Clin Nutr pmid:23632752
Won YJ et al. β-Hydroxybutyrate modulates N-type calcium channels in rat sympathetic neurons by acting as an agonist for the G-protein-coupled receptor FFA3. 2013 J. Neurosci. pmid:24305827
Matsumoto K et al. Efficient (R)-3-hydroxybutyrate production using acetyl CoA-regenerating pathway catalyzed by coenzyme A transferase. 2013 Appl. Microbiol. Biotechnol. pmid:22592551
Hodgson AB et al. Metabolic response to green tea extract during rest and moderate-intensity exercise. 2013 J. Nutr. Biochem. pmid:22974973
Riedel SL et al. Recovery of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) from Ralstonia eutropha cultures with non-halogenated solvents. 2013 Biotechnol. Bioeng. pmid:22903730
Rutty GN et al. The effect on toxicology, biochemistry and immunology investigations by the use of targeted post-mortem computed tomography angiography. 2013 Forensic Sci. Int. pmid:22704555
Zhou C et al. Renal cortical pallor--a useful macroscopic marker for metabolic derangements at autopsy. 2013 J. Forensic Sci. pmid:23488620
Maksymiak M et al. Structural characterization of biocompatible lipoic acid-oligo-(3-hydroxybutyrate) conjugates by electrospray ionization mass spectrometry. 2013 Rapid Commun. Mass Spectrom. pmid:23495024
Zhang S et al. Short-term feed restriction impairs the absorptive function of the reticulo-rumen and total tract barrier function in beef cattle. 2013 J. Anim. Sci. pmid:23422009
Duehlmeier R et al. Pancreatic insulin release and peripheral insulin sensitivity in German black headed mutton and Finish Landrace ewes: evaluation of the role of insulin resistance in the susceptibility to ovine pregnancy toxemia. 2013 Domest. Anim. Endocrinol. pmid:23422315
Li M et al. GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy. 2013 Am. J. Physiol. Renal Physiol. pmid:23467425
Masaeli E et al. Fabrication, characterization and cellular compatibility of poly(hydroxy alkanoate) composite nanofibrous scaffolds for nerve tissue engineering. 2013 PLoS ONE pmid:23468923
Suthar VS et al. Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. 2013 J. Dairy Sci. pmid:23497997
Laeger T et al. Concentrations of hormones and metabolites in cerebrospinal fluid and plasma of dairy cows during the periparturient period. 2013 J. Dairy Sci. pmid:23498004
Zarrin M et al. Long-term elevation of β-hydroxybutyrate in dairy cows through infusion: effects on feed intake, milk production, and metabolism. 2013 J. Dairy Sci. pmid:23498021
Lim JS et al. Effect of composition ratio on the thermal and physical properties of semicrystalline PLA/PHB-HHx composites. 2013 Mater Sci Eng C Mater Biol Appl pmid:23498241
Ruskin DN et al. Ketogenic diets and thermal pain: dissociation of hypoalgesia, elevated ketones, and lowered glucose in rats. 2013 J Pain pmid:23499319
Moyes KM et al. Generation of an index for physiological imbalance and its use as a predictor of primary disease in dairy cows during early lactation. 2013 J. Dairy Sci. pmid:23403197
Klevenhusen F et al. Feeding barley grain-rich diets altered electrophysiological properties and permeability of the ruminal wall in a goat model. 2013 J. Dairy Sci. pmid:23403198
Zhang S et al. Recovery of absorptive function of the reticulo-rumen and total tract barrier function in beef cattle after short-term feed restriction. 2013 J. Anim. Sci. pmid:23408814
Silva PR et al. Effects of weekly regrouping of prepartum dairy cows on metabolic, health, reproductive, and productive parameters. 2013 J. Dairy Sci. pmid:23660147
Zilberter M et al. Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease. 2013 J. Neurochem. pmid:23241062
Lomas AJ et al. Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)/collagen hybrid scaffolds for tissue engineering applications. 2013 Tissue Eng Part C Methods pmid:23281705
van der Drift SG et al. Effects of β-hydroxybutyrate and isoproterenol on lipolysis in isolated adipocytes from periparturient dairy cows and cows with clinical ketosis. 2013 Res. Vet. Sci. pmid:23256919
Derno M et al. Short-term feed intake is regulated by macronutrient oxidation in lactating Holstein cows. 2013 J. Dairy Sci. pmid:23219119
Lehmann M et al. Concomitant lipopolysaccharide-induced transfer of blood-derived components including immunoglobulins into milk. 2013 J. Dairy Sci. pmid:23219120
Shimazu T et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 2013 Science pmid:23223453
Peng Q et al. The implantable and biodegradable PHBHHx 3D scaffolds loaded with protein-phospholipid complex for sustained delivery of proteins. 2013 Pharm. Res. pmid:23224980
Lin BQ et al. Dietary restriction suppresses tumor growth, reduces angiogenesis, and improves tumor microenvironment in human non-small-cell lung cancer xenografts. 2013 Lung Cancer pmid:23199512
Courchesne-Loyer A et al. Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism. 2013 Nutrition pmid:23274095
Bohlooli M et al. Thermodynamics of a molten globule state of human serum albumin by 3-β-hydroxybutyrate as a ketone body. 2013 Int. J. Biol. Macromol. pmid:23262385
McArt JA et al. Dry period and parturient predictors of early lactation hyperketonemia in dairy cattle. 2013 J. Dairy Sci. pmid:23102961
Zebeli Q et al. Oral challenge with increasing doses of LPS modulated the patterns of plasma metabolites and minerals in periparturient dairy cows. 2013 Innate Immun pmid:23109506
Dwyer JB and Tamama K Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient. 2013 Clin. Chim. Acta pmid:23159845
Giuliodori MJ et al. Clinical endometritis in an Argentinean herd of dairy cows: risk factors and reproductive efficiency. 2013 J. Dairy Sci. pmid:23182361
Shimomura T et al. A novel, disposable, screen-printed amperometric biosensor for ketone 3-β-hydroxybutyrate fabricated using a 3-β-hydroxybutyrate dehydrogenase-mesoporous silica conjugate. 2013 Anal Bioanal Chem pmid:23096941
Memon S and Pratten MK Teratogenic effects of diabetic conditions in chick heart in ovo and in micromass culture may be prevented by addition of vitamin C and folic acid. 2013 Reprod. Toxicol. pmid:23099339
Cheng B et al. d-β-Hydroxybutyrate inhibited the apoptosis of PC12 cells induced by H2O2 via inhibiting oxidative stress. 2013 Neurochem. Int. pmid:23022628