(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Short Bowel Syndrome D012778 3 associated lipids
Aortopulmonary Septal Defect D001028 1 associated lipids
Thyrotoxicosis D013971 3 associated lipids
Wounds, Nonpenetrating D014949 4 associated lipids
Hyperglycemic Hyperosmolar Nonketotic Coma D006944 4 associated lipids
Muscle Rigidity D009127 4 associated lipids
Bulimia D002032 3 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Exostoses, Multiple Hereditary D005097 3 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Fructose-1,6-Diphosphatase Deficiency D015319 1 associated lipids
Syndrome D013577 4 associated lipids
Trypanosomiasis, African D014353 5 associated lipids
Liver Failure D017093 5 associated lipids
Hepatitis, Alcoholic D006519 5 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Spinal Muscular Atrophies of Childhood D014897 1 associated lipids
Lipoma D008067 1 associated lipids
Hyperandrogenism D017588 5 associated lipids
Parvoviridae Infections D010322 4 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Authors Title Published Journal PubMed Link
Kurihara M et al. Inhibitory effect of β-hydroxybutyric acid on L-type Ca(2+) current under β-adrenergic stimulation in guinea pig cardiac ventricular myocytes. 2012 Fukushima J Med Sci pmid:23237870
Zhang J et al. NMR-based metabolomics study of canine bladder cancer. 2012 Biochim. Biophys. Acta pmid:22967815
Abdelwahab MG et al. The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma. 2012 PLoS ONE pmid:22563484
Anis SN et al. Enhanced recovery and purification of P(3HB-co-3HHx) from recombinant Cupriavidus necator using alkaline digestion method. 2012 Appl. Biochem. Biotechnol. pmid:22569781
Bjerre-Harpøth V et al. Metabolic and production profiles of dairy cows in response to decreased nutrient density to increase physiological imbalance at different stages of lactation. 2012 J. Dairy Sci. pmid:22541465
Lomander H et al. Supplemental feeding with glycerol or propylene glycol of dairy cows in early lactation--effects on metabolic status, body condition, and milk yield. 2012 J. Dairy Sci. pmid:22541468
Mueller D et al. Biotransformation of diclofenac and effects on the metabolome of primary human hepatocytes upon repeated dose exposure. 2012 Eur J Pharm Sci pmid:22330146
Laarman AH et al. Effects of feeding a calf starter on molecular adaptations in the ruminal epithelium and liver of Holstein dairy calves. 2012 J. Dairy Sci. pmid:22541487
Yuan K et al. Effect of rumen-protected niacin on lipid metabolism, oxidative stress, and performance of transition dairy cows. 2012 J. Dairy Sci. pmid:22541495
Lei J et al. Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells. 2012 Amino Acids pmid:22543725
Roberts T et al. Metabolic parameters in transition cows as indicators for early-lactation culling risk. 2012 J. Dairy Sci. pmid:22612941
Stocks SE and Allen MS Hypophagic effects of propionate increase with elevated hepatic acetyl coenzyme A concentration for cows in the early postpartum period. 2012 J. Dairy Sci. pmid:22612960
Zhang L et al. Distinguishing pancreatic cancer from chronic pancreatitis and healthy individuals by (1)H nuclear magnetic resonance-based metabonomic profiles. 2012 Clin. Biochem. pmid:22613268
Kimura R et al. Acute exposure to the mitochondrial complex I toxin rotenone impairs synaptic long-term potentiation in rat hippocampal slices. 2012 CNS Neurosci Ther pmid:22613619
Arora S and Menchine M The role of point-of-care β-hydroxybutyrate testing in the diagnosis of diabetic ketoacidosis: a review. 2012 Hosp Pract (1995) pmid:22615081
Weingart C et al. Validation of a portable hand-held whole-blood ketone meter for use in cats. 2012 Vet Clin Pathol pmid:22250845
Krueger T and Melendez P Effect of ghrelin on feed intake and metabolites in lambs. 2012 Appetite pmid:22280977
Ster C et al. Effect of postcalving serum nonesterified fatty acids concentration on the functionality of bovine immune cells. 2012 J. Dairy Sci. pmid:22281335
Palmiere C et al. Is the formula of Traub still up to date in antemortem blood glucose level estimation? 2012 Int. J. Legal Med. pmid:22327538
Yang MJ et al. Bioconversion of ethyl (R)-4-cyano-3-hydroxybutyate into (R)-ethyl-3-hydroxyglutarate via an indirect pathway by Rhodococcus boritolerans. 2012 Biotechnol. Lett. pmid:22261862
van der Drift SG et al. Genetic and nongenetic variation in plasma and milk β-hydroxybutyrate and milk acetone concentrations of early-lactation dairy cows. 2012 J. Dairy Sci. pmid:22939798
Gözke G et al. Electrofiltration as a purification strategy for microbial poly-(3-hydroxybutyrate). 2012 Bioresour. Technol. pmid:22940329
Martin R et al. [Relationships between different parameters for the evaluation of the energy balance and the differential cell count in milk from cows with healthy udders]. 2012 Tierarztl Prax Ausg G Grosstiere Nutztiere pmid:22911228
Gahlawat G and Srivastava AK Estimation of fundamental kinetic parameters of polyhydroxybutyrate fermentation process of Azohydromonas australica using statistical approach of media optimization. 2012 Appl. Biochem. Biotechnol. pmid:22915234
Stone WC et al. Brown midrib corn silage fed during the peripartal period increased intake and resulted in a persistent increase in milk solids yield of Holstein cows. 2012 J. Dairy Sci. pmid:22959939
van der Drift SG et al. Routine detection of hyperketonemia in dairy cows using Fourier transform infrared spectroscopy analysis of β-hydroxybutyrate and acetone in milk in combination with test-day information. 2012 J. Dairy Sci. pmid:22916893
van der Drift SG et al. Protein and fat mobilization and associations with serum β-hydroxybutyrate concentrations in dairy cows. 2012 J. Dairy Sci. pmid:22916895
Gao F et al. Effect of prepartum maternal energy density on the growth performance, immunity, and antioxidation capability of neonatal calves. 2012 J. Dairy Sci. pmid:22818465
Kawata Y et al. Efficient secreted production of (R)-3-hydroxybutyric acid from living Halomonas sp. KM-1 under successive aerobic and microaerobic conditions. 2012 Appl. Microbiol. Biotechnol. pmid:22718250
Maillo V et al. Influence of lactation on metabolic characteristics and embryo development in postpartum Holstein dairy cows. 2012 J. Dairy Sci. pmid:22720941
Kelso EJ et al. Sex differences in fuel use and metabolism during development in fasting juvenile northern elephant seals. 2012 J. Exp. Biol. pmid:22786640
Luan G et al. Ketogenic diet reduces Smac/Diablo and cytochrome c release and attenuates neuronal death in a mouse model of limbic epilepsy. 2012 Brain Res. Bull. pmid:22796483
Doelman J et al. Transcript profiling of the ruminant liver indicates a unique program of transcriptional regulation of ketogenic enzymes during food restriction. 2012 Comp. Biochem. Physiol. Part D Genomics Proteomics pmid:22748507
Fraga CM et al. Fatty acids oxidation and alternative energy sources detected in Taenia crassiceps cysticerci after host treatment with antihelminthic drugs. 2012 Exp. Parasitol. pmid:22465501
Borchardt S and Staufenbiel R Evaluation of the use of nonesterified fatty acids and β-hydroxybutyrate concentrations in pooled serum samples for herd-based detection of subclinical ketosis in dairy cows during the first week after parturition. 2012 J. Am. Vet. Med. Assoc. pmid:22471831
Blad CC et al. Novel 3,6,7-substituted pyrazolopyrimidines as positive allosteric modulators for the hydroxycarboxylic acid receptor 2 (GPR109A). 2012 J. Med. Chem. pmid:22420767
Gambhir D et al. GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy. 2012 Invest. Ophthalmol. Vis. Sci. pmid:22427566
Saremi B et al. Bovine haptoglobin as an adipokine: serum concentrations and tissue expression in dairy cows receiving a conjugated linoleic acids supplement throughout lactation. 2012 Vet. Immunol. Immunopathol. pmid:22498004
Heninger M Postmortem vitreous beta-hydroxybutyrate: interpretation in a forensic setting. 2012 J. Forensic Sci. pmid:22458736
Li P et al. Alterations of fatty acid β-oxidation capability in the liver of ketotic cows. 2012 J. Dairy Sci. pmid:22459824
Hiraishi T et al. Display of functionally active PHB depolymerase on Escherichia coli cell surface. 2012 Macromol Biosci pmid:22095689
Peng Q et al. A rapid-acting, long-acting insulin formulation based on a phospholipid complex loaded PHBHHx nanoparticles. 2012 Biomaterials pmid:22112760
Senosy WS et al. Influences of metabolic traits on subclinical endometritis at different intervals postpartum in high milking cows. 2012 Reprod. Domest. Anim. pmid:22053752
Aroch I et al. A retrospective study of serum β-hydroxybutyric acid in 215 ill cats: clinical signs, laboratory findings and diagnoses. 2012 Vet. J. pmid:21316992
Álvarez-Rodríguez J et al. Rumen fermentation and histology in light lambs as affected by forage supply and lactation length. 2012 Res. Vet. Sci. pmid:21458834
Devenny JJ et al. Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. 2012 Obesity (Silver Spring) pmid:22402735
Walsh SW et al. Effect of the metabolic environment at key stages of follicle development in cattle: focus on steroid biosynthesis. 2012 Physiol. Genomics pmid:22414914
Dutta T et al. Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes. 2012 Diabetes pmid:22415876
Sui L et al. Effect of poly-β-hydroxybutyrate on Chinese mitten crab, Eriocheir sinensis, larvae challenged with pathogenic Vibrio anguillarum. 2012 J. Fish Dis. pmid:22417317
Thompson IM et al. Effects of lactation and pregnancy on metabolic and hormonal responses and expression of selected conceptus and endometrial genes of Holstein dairy cattle. 2012 J. Dairy Sci. pmid:22863093
Chapinal N et al. Herd-level association of serum metabolites in the transition period with disease, milk production, and early lactation reproductive performance. 2012 J. Dairy Sci. pmid:22863094
Ghorbani A et al. Performance and metabolic responses of Holstein calves to supplemental chromium in colostrum and milk. 2012 J. Dairy Sci. pmid:22863099
Heidarpour M et al. Acute-phase protein concentration and metabolic status affect the outcome of treatment in cows with clinical and subclinical endometritis. 2012 Vet. Rec. pmid:22865113
García-Hidalgo J et al. Extracellular production of Streptomyces exfoliatus poly(3-hydroxybutyrate) depolymerase in Rhodococcus sp. T104: determination of optimal biocatalyst conditions. 2012 Appl. Microbiol. Biotechnol. pmid:21845385
Tsutsui H et al. Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS. 2012 Anal Bioanal Chem pmid:22895741
Righi V et al. MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma. 2012 Oncol. Rep. pmid:22824994
Hockenhull J et al. Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples. 2012 Forensic Sci. Int. pmid:21840144
Liu SF et al. Dioscorea alata attenuates renal interstitial cellular fibrosis by regulating Smad- and epithelial-mesenchymal transition signaling pathways. 2012 PLoS ONE pmid:23144821
Smejkal P et al. Separation of carboxylic acids in human serum by isotachophoresis using a commercial field-deployable analytical platform combined with in-house glass microfluidic chips. 2012 Anal. Chim. Acta pmid:23146402
Constantin RP et al. Prooxidant activity of fisetin: effects on energy metabolism in the rat liver. 2011 Mar-Apr J. Biochem. Mol. Toxicol. pmid:20957679
Rodríguez-Merchán B et al. [Capillary beta-hydroxybutyrate determination for monitoring diabetic ketoacidosis]. 2011 Aug-Sep Endocrinol Nutr pmid:21737365
Brunner MP et al. Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization. 2011 Circ Cardiovasc Genet pmid:22010138
Moazzami AA et al. Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients. 2011 J. Nutr. pmid:22013201
Chapinal N et al. The association of serum metabolites with clinical disease during the transition period. 2011 J. Dairy Sci. pmid:21943741
Kreipe L et al. First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in nonketotic early lactating cows. 2011 J. Dairy Sci. pmid:21943742
Bernier-Dodier P et al. Effect of dry period management on mammary gland function and its endocrine regulation in dairy cows. 2011 J. Dairy Sci. pmid:21943744
Morey SD et al. Effects of encapsulated niacin on metabolism and production of periparturient dairy cows. 2011 J. Dairy Sci. pmid:21943760
Yu HY et al. Clinical utility of Abbott Precision Xceed Pro® ketone meter in diabetic patients. 2011 Pediatr Diabetes pmid:22034832
Otis JP et al. Cholesterol and lipoprotein dynamics in a hibernating mammal. 2011 PLoS ONE pmid:22195001
Tanaka K et al. Cell growth and P(3HB) accumulation from CO2 of a carbon monoxide-tolerant hydrogen-oxidizing bacterium, Ideonella sp. O-1. 2011 Appl. Microbiol. Biotechnol. pmid:21695533
Meier H et al. [Ethanol, sugar, acid and coma]. 2011 Praxis (Bern 1994) pmid:21698566
Numis AL et al. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. 2011 Epilepsy Res. pmid:21700429
Liu F et al. Metabolic engineering of Aeromonas hydrophila 4AK4 for production of copolymers of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoate. 2011 Bioresour. Technol. pmid:21680176
Li XB et al. Renal function of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21672951
Deng-Bryant Y et al. Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. 2011 J. Neurotrauma pmid:21635175
Ruprechter G et al. Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes. 2011 Acta Vet. Scand. pmid:21635772
Harris DL et al. Cot-side electroencephalography monitoring is not clinically useful in the detection of mild neonatal hypoglycemia. 2011 J. Pediatr. pmid:21658714
Collison KS et al. Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. 2011 Br. J. Nutr. pmid:21429276
Lund TM et al. β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons. 2011 Neurochem. Int. pmid:21684314
Hayashi T et al. Positional asphyxia or diabetic ketoacidosis? A case report. 2011 Leg Med (Tokyo) pmid:21377395
Sun AK et al. [Fabrication of larynx-shape tissue engineered cartilage by means of filling together with wrapping with pedicle myofascial flap]. 2011 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22336014
Lassala A et al. Parenteral administration of L-arginine enhances fetal survival and growth in sheep carrying multiple fetuses. 2011 J. Nutr. pmid:21430253
Bényei B et al. Plasma progesterone, metabolic hormones and beta-hydroxybutyrate in Holstein-Friesian cows after superovulation. 2011 Acta Vet. Hung. pmid:22079709
Dutton SB et al. Protective effect of the ketogenic diet in Scn1a mutant mice. 2011 Epilepsia pmid:21801172
Hsu WY et al. Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21856256
Valayannopoulos V et al. Successful treatment of severe cardiomyopathy in glycogen storage disease type III With D,L-3-hydroxybutyrate, ketogenic and high-protein diet. 2011 Pediatr. Res. pmid:21857385
Zhang Z et al. Concentrations of sodium, potassium, magnesium, and iron in the serum of dairy cows with subclinical ketosis. 2011 Biol Trace Elem Res pmid:21739162
Krogh MA et al. Latent class evaluation of a milk test, a urine test, and the fat-to-protein percentage ratio in milk to diagnose ketosis in dairy cows. 2011 J. Dairy Sci. pmid:21524525
Shah TD et al. The characterization of a unique Trypanosoma brucei β-hydroxybutyrate dehydrogenase. 2011 Mol. Biochem. Parasitol. pmid:21767577
Zebeli Q et al. Perturbations of plasma metabolites correlated with the rise of rumen endotoxin in dairy cows fed diets rich in easily degradable carbohydrates. 2011 J. Dairy Sci. pmid:21524527
Norouzian MA et al. Rumen development and growth of Balouchi lambs offered alfalfa hay pre- and post-weaning. 2011 Trop Anim Health Prod pmid:21465104
Minlebaev M and Khazipov R Antiepileptic effects of endogenous beta-hydroxybutyrate in suckling infant rats. 2011 Epilepsy Res. pmid:21470827
Valergakis GE et al. Phenotypic association between energy balance indicators and reproductive performance in primiparous Holstein cows. 2011 Vet. Rec. pmid:21493532
Chmiel-Perzyńska I et al. Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. 2011 Neurotox Res pmid:20838951
Tisi DK et al. Fetal exposure to altered amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1 occurs before screening for gestational diabetes mellitus. 2011 Diabetes Care pmid:20855548
Zhang D et al. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959534
Legge M et al. Energy substrate utilization in the common brushtailed possum (Trichosurus vulpecula) using intravenous tolerance tests. 2011 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:20977945
Jackson RA et al. Energy metabolites in pre- and postpartum dairy cattle as predictors of reproductive disorders. 2011 Vet. Rec. pmid:21546407
Albano N et al. Plasma metabolite levels predict bird growth rates: A field test of model predictive ability. 2011 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:21575739
Bielohuby M et al. Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20943751