(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Weight Loss D015431 56 associated lipids
Parkinson Disease D010300 53 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Starvation D013217 47 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Epilepsy D004827 35 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Uremia D014511 33 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Liver Diseases D008107 31 associated lipids
Obesity D009765 29 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Hyperinsulinism D006946 27 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Cattle Diseases D002418 24 associated lipids
Cholestasis D002779 23 associated lipids
Hypoxia D000860 23 associated lipids
Birth Weight D001724 23 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Hypoxia-Ischemia, Brain D020925 22 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Hyperglycemia D006943 21 associated lipids
Vomiting D014839 21 associated lipids
Cachexia D002100 21 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Pregnancy Complications D011248 19 associated lipids
Albuminuria D000419 18 associated lipids
Parkinson Disease, Secondary D010302 17 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Brain Neoplasms D001932 15 associated lipids
Reye Syndrome D012202 14 associated lipids
Acidosis D000138 13 associated lipids
Glucose Intolerance D018149 13 associated lipids
Ketosis D007662 13 associated lipids
Corneal Diseases D003316 13 associated lipids
Hypoglycemia D007003 13 associated lipids
Critical Illness D016638 13 associated lipids
Hypocalcemia D006996 12 associated lipids
Disease Resistance D060467 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Death, Sudden D003645 12 associated lipids
Cat Diseases D002371 12 associated lipids
Metabolic Diseases D008659 12 associated lipids
Dehydration D003681 11 associated lipids
Thinness D013851 11 associated lipids
Shock D012769 11 associated lipids
Congenital Abnormalities D000013 11 associated lipids
Amyotrophic Lateral Sclerosis D000690 11 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Fatigue D005221 10 associated lipids
Glycosuria D006029 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Sheep Diseases D012757 10 associated lipids
Foreign-Body Reaction D005549 10 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Trematode Infections D014201 8 associated lipids
Anorexia D000855 8 associated lipids
Irritable Bowel Syndrome D043183 8 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Authors Title Published Journal PubMed Link
Saeb M et al. Physiological response of dromedary camels to road transportation in relation to circulating levels of cortisol, thyroid hormones and some serum biochemical parameters. 2010 Trop Anim Health Prod pmid:19544085
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Hajiali H et al. Preparation of a novel biodegradable nanocomposite scaffold based on poly (3-hydroxybutyrate)/bioglass nanoparticles for bone tissue engineering. 2010 J Mater Sci Mater Med pmid:20372984
Denny CA et al. Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice. 2010 J. Neurochem. pmid:20374428
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DeGaris PJ et al. Effects of increasing days of exposure to prepartum diets on the concentration of certain blood metabolites in dairy cows. 2010 Aust. Vet. J. pmid:20402701
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Warren R Alcoholic lunch did not cause clinically relevant ketosis. 2010 QJM pmid:19793870
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Voyvoda H and Erdogan H Use of a hand-held meter for detecting subclinical ketosis in dairy cows. 2010 Res. Vet. Sci. pmid:20471047
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Byard RW and Zhou C Erosive gastritis, Armanni-Ebstein phenomenon and diabetic ketoacidosis. 2010 Forensic Sci Med Pathol pmid:20632132
Pradella JG et al. High-cell-density poly (3-hydroxybutyrate) production from sucrose using Burkholderia sacchari culture in airlift bioreactor. 2010 Bioresour. Technol. pmid:20580221
Hölscher T et al. Production of the chiral compound (R)-3-hydroxybutyrate by a genetically engineered methylotrophic bacterium. 2010 Appl. Environ. Microbiol. pmid:20581197
Youssef MA et al. Ketosis in buffalo (Bubalus bubalis): clinical findings and the associated oxidative stress level. 2010 Trop Anim Health Prod pmid:20582718
Ibrahim MH et al. Isolation and characterization of new poly(3HB)-accumulating star-shaped cell-aggregates-forming thermophilic bacteria. 2010 J. Appl. Microbiol. pmid:20584099
Lynch EM et al. Characterisation of physiological and immunological responses in beef cows to abrupt weaning and subsequent housing. 2010 BMC Vet. Res. pmid:20646268
Earley B et al. Effect of road transport for up to 24 hours followed by twenty-four hour recovery on live weight and physiological responses of bulls. 2010 BMC Vet. Res. pmid:20646269
Kitaoka R et al. Increased noradrenergic activity in the ventromedial hypothalamus during treadmill running in rats. 2010 J. Nutr. Sci. Vitaminol. pmid:20651459
Choi HC et al. Two-dimensional heterospectral correlation analysis of X-ray photoelectron spectra and infrared spectra for spin-coated films of biodegradable poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) copolymers. 2010 J Phys Chem B pmid:20690586
Huang ST et al. Design and synthesis of a long-wavelength latent fluorogenic substrate for salicylate hydroxylase: a useful fluorimetric indicator for analyte determination by dehydrogenase-coupled biosensors. 2010 Anal. Chem. pmid:20695438
Samiei A et al. An evaluation of beta-hydroxybutyrate in milk and blood for prediction of subclinical ketosis in dairy cows. 2010 Pol J Vet Sci pmid:20731192
Zeugswetter F et al. Efficacy of plasma beta-hydroxybutyrate concentration as a marker for diabetes mellitus in acutely sick cats. 2010 J. Feline Med. Surg. pmid:20117951
Fisher AD et al. The effects of 12, 30, or 48 hours of road transport on the physiological and behavioral responses of sheep. 2010 J. Anim. Sci. pmid:20154169
Samoilova M et al. Chronic in vitro ketosis is neuroprotective but not anti-convulsant. 2010 J. Neurochem. pmid:20163521
Song H et al. Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20179248
Ramnanan CJ et al. Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo. 2010 Diabetes pmid:20185816
Kafi M and Mirzaei A Effects of first postpartum progesterone rise, metabolites, milk yield, and body condition score on the subsequent ovarian activity and fertility in lactating Holstein dairy cows. 2010 Trop Anim Health Prod pmid:20140511
Stout PA et al. Quantitative analysis of gamma-hydroxybutyrate at endogenous concentrations in hair using liquid chromatography tandem mass spectrometry. 2010 J. Forensic Sci. pmid:20141559
Pan Y et al. Dietary supplementation with medium-chain TAG has long-lasting cognition-enhancing effects in aged dogs. 2010 Br. J. Nutr. pmid:20141643
Zawidlak-Wegrzyńska B et al. Synthesis and antiproliferative properties of ibuprofen-oligo(3-hydroxybutyrate) conjugates. 2010 Eur J Med Chem pmid:20171760
Rollin E et al. The effect of injectable butaphosphan and cyanocobalamin on postpartum serum beta-hydroxybutyrate, calcium, and phosphorus concentrations in dairy cattle. 2010 J. Dairy Sci. pmid:20172218
Thio LL et al. A ketogenic diet does not impair rat behavior or long-term potentiation. 2010 Epilepsia pmid:20132289
De Schryver P et al. Poly-beta-hydroxybutyrate (PHB) increases growth performance and intestinal bacterial range-weighted richness in juvenile European sea bass, Dicentrarchus labrax. 2010 Appl. Microbiol. Biotechnol. pmid:20094715
Kumar A et al. Metabolomic analysis of serum by (1) H NMR spectroscopy in amyotrophic lateral sclerosis. 2010 Clin. Chim. Acta pmid:20096678
Mountassif D et al. Structural and catalytic properties of the D-3-hydroxybutyrate dehydrogenase from Pseudomonas aeruginosa. 2010 Curr. Microbiol. pmid:20052585
Kiku Y et al. Decrease in bovine CD14 positive cells in colostrum is associated with the incidence of mastitis after calving. 2010 Vet. Res. Commun. pmid:20077004
Zhang Z et al. Evaluation of the change of serum copper and zinc concentrations of dairy cows with subclinical ketosis. 2010 Biol Trace Elem Res pmid:20101474
Zhang XX and Rainey PB Bet hedging in the underworld. 2010 Genome Biol. pmid:21062509
Henderson DW and Schlesinger DP Use of a point-of-care beta-hydroxybutyrate sensor for detection of ketonemia in dogs. 2010 Can. Vet. J. pmid:21119867
Kirmse K et al. GABA depolarizes immature neocortical neurons in the presence of the ketone body ß-hydroxybutyrate. 2010 J. Neurosci. pmid:21106838
Stasiak P et al. In vivo assessment of parenteral formulations of oligo(3-hydroxybutyric Acid) conjugates with the model compound Ibuprofen. 2010 AAPS PharmSciTech pmid:21088943
Padidela R et al. Focal congenital hyperinsulinism in a patient with septo-optic dysplasia. 2010 Nat Rev Endocrinol pmid:20842182
Pavlides S et al. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism. 2010 Cell Cycle pmid:20861672
Negoda A et al. Importance of oligo-R-3-hydroxybutyrates to S. lividans KcsA channel structure and function. 2010 Mol Biosyst pmid:20862428
Schwartzkroin PA et al. Does ketogenic diet alter seizure sensitivity and cell loss following fluid percussion injury? 2010 Epilepsy Res. pmid:20863664
Kaufmann TB et al. Correlations between periparturient serum concentrations of non-esterified fatty acids, beta-hydroxybutyric acid, bilirubin, and urea and the occurrence of clinical and subclinical postpartum bovine endometritis. 2010 BMC Vet. Res. pmid:20979598
Kalaitzakis E et al. Clinicopathological evaluation of downer dairy cows with fatty liver. 2010 Can. Vet. J. pmid:20808573
Morgante M et al. Preliminary study on metabolic profile of pregnant and non-pregnant ewes with high or low degree of behavioral lateralization. 2010 Anim. Sci. J. pmid:21108694
Yang XD et al. Enhanced insulin production from murine islet beta cells incubated on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). 2010 J Biomed Mater Res A pmid:19235213
McGuire LP et al. Determining feeding state and rate of mass change in insectivorous bats using plasma metabolite analysis. 2009 Nov-Dec Physiol. Biochem. Zool. pmid:19799521
Di Tommaso M et al. Evaluation of a portable meter to measure ketonemia and comparison with ketonuria for the diagnosis of canine diabetic ketoacidosis. 2009 May-Jun J. Vet. Intern. Med. pmid:19645834
Young DC et al. Synthesis of dideoxymycobactin antigens presented by CD1a reveals T cell fine specificity for natural lipopeptide structures. 2009 J. Biol. Chem. pmid:19605355
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Biswas A et al. Production of poly-3-hydroxyalkanoic acids by a moderately halophilic bacterium, Halomonas marina HMA 103 isolated from solar saltern of Orissa, India. 2009 Acta Microbiol Immunol Hung pmid:19621765
Chen Z et al. Synthesis, characterization and cell compatibility of novel poly(ester urethane)s based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) prepared by melting polymerization. 2009 J Biomater Sci Polym Ed pmid:19622282
Bigrigg JK et al. Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19625693
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Jiang Y and Chen Y The effects of the ratio of propionate to acetate on the transformation and composition of polyhydroxyalkanoates with enriched cultures of glycogen-accumulating organisms. 2009 Environ Technol pmid:19438056
Nehlig A et al. The ketogenic diet has no effect on the expression of spike-and-wave discharges and nutrient transporters in genetic absence epilepsy rats from Strasbourg. 2009 J. Neurochem. pmid:19393029
Han X et al. Chemo-enzymatic synthesis of polyhydroxyalkanoate by an improved two-phase reaction system (TPRS). 2009 J. Biosci. Bioeng. pmid:19914586
Hassan HM and Cooper GA Determination of beta-hydroxybutyrate in blood and urine using gas chromatography- mass spectrometry. 2009 J Anal Toxicol pmid:19874659
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Yamada M et al. Microbial production of lactate-enriched poly[(R)-lactate-co-(R)-3-hydroxybutyrate] with novel thermal properties. 2009 Biomacromolecules pmid:19249863
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Bian YZ et al. Evaluation of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) conduits for peripheral nerve regeneration. 2009 Biomaterials pmid:18849069
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Sun M et al. Enhanced cell affinity of the silk fibroin- modified PHBHHx material. 2009 J Mater Sci Mater Med pmid:19333570
Hoque MM et al. Structure of D-3-hydroxybutyrate dehydrogenase prepared in the presence of the substrate D-3-hydroxybutyrate and NAD+. 2009 Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. pmid:19342772
Stasiak P et al. Characterisation of a novel conjugate of ibuprofen with 3-hydroxybutyric acid oligomers. 2009 J. Pharm. Pharmacol. pmid:19703357
Porta N et al. Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, exerts anticonvulsive properties. 2009 Epilepsia pmid:19054409
Andrews MT et al. Adaptive mechanisms regulate preferred utilization of ketones in the heart and brain of a hibernating mammal during arousal from torpor. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19052316
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Li Y et al. Stoichiometric analysis of dissolved organic carbon flux into storage and growth in aerobic granules culture. 2009 Biotechnol J pmid:19137568
Nakashima K et al. Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor. 2009 J. Biochem. pmid:19122202
Gatta B et al. Acute effects of pharmacological modifications of fatty acid metabolism on human satiety. 2009 Br. J. Nutr. pmid:19079943
Pan P et al. Uracil as nucleating agent for bacterial poly[(3-hydroxybutyrate)-co-(3-hydroxyhexanoate)] copolymers. 2009 Macromol Biosci pmid:19156688
Kim J et al. Fabrication of biodegradable nanofibers of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) via electrospinning. 2009 J Nanosci Nanotechnol pmid:19441421