(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Sheep Diseases D012757 10 associated lipids
Stomach Diseases D013272 7 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
[Prospective multicenter study on long-term ketogenic diet therapy for intractable childhood epilepsy]. 2013 Zhonghua Er Ke Za Zhi pmid:23927801
Sun AK et al. [Fabrication of larynx-shape tissue engineered cartilage by means of filling together with wrapping with pedicle myofascial flap]. 2011 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22336014
Yang N and Jiang Z [The kinetic observation of serum ketone body levels in surgical patients receiving MCT or LCT emulsions]. 1992 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:1303814
Ren FQ et al. [Evaluation of enzymatic method for determination of serum beta-hydroxybutyrate and its clinical application]. 2003 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:14714316
Zhao Y et al. [Biocompatibility of p(3HB-co-3HH) and marrow mesenchymal stem cells]. 2004 Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi pmid:15065407
Mudron P et al. Plasma and liver alpha-tocopherol in dairy cows with left abomasal displacement and fatty liver. 1997 Zentralbl Veterinarmed A pmid:9284634
Henze P et al. Spontaneous pregnancy toxaemia (ketosis) in sheep and the role of insulin. 1998 Zentralbl Veterinarmed A pmid:9719756
Kauppinen K ALAT, AP, ASAT, GGT, OCT activities and urea and total bilirubin concentrations in plasma of normal and ketotic dairy cows. 1984 Zentralbl Veterinarmed A pmid:6150588
Hoerstke M and Dirksen G [Ketogenesis and rumen function following intraruminal administration of saturated fatty acids (C8, C10, C12) in cattle]. 1981 Zentralbl Veterinarmed A pmid:6789577
Stangassinger M et al. [Diabetes mellitus in dwarf goats; model experiments with streptozocin]. 1982 Zentralbl Veterinarmed A pmid:6215806
Geishauser T et al. The association between selected metabolic parameters and left abomasal displacement in dairy cows. 1998 Zentralbl Veterinarmed A pmid:9838862
Dirksen G and Breitner W A new quick-test for semiquantitative determination of beta-hydroxybutyric acid in bovine milk. 1993 Nov-Dec Zentralbl Veterinarmed A pmid:8135084
Sandner N et al. [The effect of glucocorticoid on the glucose metabolism of pigmy goats. 1. Selected metabolites of energy metabolism]. 1990 Zentralbl Veterinarmed A pmid:2110400
Hammadeh ME et al. [Effects of ovarian stimulation on serum concentrations of lipids and ketone bodies in patients undergoing IVF/ICSI treatment]. 2004 Zentralbl Gynakol pmid:15112131
Krauss A et al. [Biochemical studies of amniotic fluid]. 1983 Zentralbl Gynakol pmid:6845916
Fölsch UR et al. Effect of long-term fasting of obese patients on pancreatic exocrine function, gastrointestinal hormones and bicarbonate concentration in plasma. 1984 Z Gastroenterol pmid:6207670
Langhans W et al. [Effect of carbohydrate intake during a long distance run on work capacity and metabolism]. 1992 Z Ernahrungswiss pmid:1585683
Georgieff M et al. [Regulation of ketone body levels before and following elective surgical operations during different intravenous feedings]. 1982 Z Ernahrungswiss pmid:6815908
Meijer GW and Beynen AC Influence of dietary carnitine on lipid and carbohydrate metabolism in rats. 1988 Z Ernahrungswiss pmid:3206914
Sachs M and Förster H [Effect of caffeine on various metabolic parameters in vivo]. 1984 Z Ernahrungswiss pmid:6390995
Silberbauer C et al. Breakfasts with different fiber and macronutrient contents do not differentially affect timing, size or microstructure of the subsequent lunch. 1996 Z Ernahrungswiss pmid:9000333
Jeong HJ et al. The ketogenic diet suppresses the cathepsin E expression induced by kainic acid in the rat brain. 2010 Yonsei Med. J. pmid:20635438
Sánchez SF et al. Nutritional condition affects the disposition kinetics of albendazole in cattle. 1996 Xenobiotica pmid:8730922
Hehenberger K et al. Inhibited proliferation of fibroblasts derived from chronic diabetic wounds and normal dermal fibroblasts treated with high glucose is associated with increased formation of l-lactate. 1998 Mar-Apr Wound Repair Regen pmid:9776856
Keller U et al. Protein-sparing therapy in the postoperative period. 1986 World J Surg pmid:3083595
Shutenko ZhV et al. [Potentiation of the antiketogenic effect of exogenous glucose with the help of the new beta-oxidation inhibitor mildronate--3-(2,2,2-trimethylhydrazine)propionate]. 1991 Mar-Apr Vopr. Med. Khim. pmid:1897198
Balasiavichius RV et al. [Effect of ischemia on the functional activity and membrane permeability of heart mitochondria]. 1984 Mar-Apr Vopr. Med. Khim. pmid:6331001
Enemark JM et al. Failure to improve energy balance or dehydration by drenching transition cows with water and electrolytes at calving. 2009 Vet. Res. Commun. pmid:18686006
Enemark JM et al. An evaluation of parameters for the detection of subclinical rumen acidosis in dairy herds. 2004 Vet. Res. Commun. pmid:15609869
Kiku Y et al. Decrease in bovine CD14 positive cells in colostrum is associated with the incidence of mastitis after calving. 2010 Vet. Res. Commun. pmid:20077004
Sakha M et al. Bovine subclinical ketosis in dairy herds in Iran. 2007 Vet. Res. Commun. pmid:17287886
Xu C and Wang Z Comparative proteomic analysis of livers from ketotic cows. 2008 Vet. Res. Commun. pmid:18080212
Kornalijnslijper E et al. The effect of milk production level on host resistance of dairy cows, as assessed by the severity of experimental Escherichia coli mastitis. 2003 Nov-Dec Vet. Res. pmid:14746768
Laven RA and Andrews AH Control of fatty liver syndrome in a Jersey herd by a change of diet and the use of recombinant bovine somatotrophin. 1998 Vet. Rec. pmid:9481826
Jorritsma R et al. Effects of a single dose of dexamethasone-21-isonicotinate on the metabolism of heifers in early lactation. 2004 Vet. Rec. pmid:15551926
Warriss PD et al. Response of newly hatched chicks to inanition. 1992 Vet. Rec. pmid:1497703
Kelly JM and Whitaker DA Blood composition and liver fat in dairy cows. 1983 Vet. Rec. pmid:6623878
Leonard F et al. Possible effect of pH on the survival of leptospires in cattle urine. 1992 Vet. Rec. pmid:1441163
Gaal T et al. Blood composition and liver fat in post parturient dairy cows. 1983 Vet. Rec. pmid:6684351
Li XB et al. Renal function of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21672951
Rice DA et al. Ketosis in dairy cows caused by low levels of lincomycin in concentrate feed. 1983 Vet. Rec. pmid:6649392
Valergakis GE et al. Phenotypic association between energy balance indicators and reproductive performance in primiparous Holstein cows. 2011 Vet. Rec. pmid:21493532
Heidarpour M et al. Acute-phase protein concentration and metabolic status affect the outcome of treatment in cows with clinical and subclinical endometritis. 2012 Vet. Rec. pmid:22865113
Zhang ZG et al. Serum antioxidant capacity of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21257536
Knowles TG et al. Effects on cattle of transportation by road for up to 31 hours. 1999 Vet. Rec. pmid:10606018
Jackson RA et al. Energy metabolites in pre- and postpartum dairy cattle as predictors of reproductive disorders. 2011 Vet. Rec. pmid:21546407
Knowles TG et al. Effects of feeding, watering and resting intervals on lambs transported by road and ferry to France. 1996 Vet. Rec. pmid:8903011
Moorby JM et al. Aspects of the metabolism of dairy cows during the incubation of bovine spongiform encephalopathy. 2000 Vet. Rec. pmid:11072985
Whitaker DA et al. Milk production, weight changes and blood biochemical measurements in dairy cattle receiving recombinant bovine somatotropin. 1989 Vet. Rec. pmid:2929083
Maisey I et al. Efficacy of recombinant bovine somatotrophin in the treatment of fat cow syndrome. 1993 Vet. Rec. pmid:8236657
Cook NB et al. Concentrations of ketones in milk in early lactation, and reproductive performance of dairy cows. 2001 Vet. Rec. pmid:11465262
Whitaker DA et al. Some effects of nutrition and management on the fertility of dairy cattle. 1993 Vet. Rec. pmid:8212484
Cantley CE et al. Serum fructosamine in ovine pregnancy toxaemia: a possible prognostic index. 1991 Vet. Rec. pmid:1866884
Katunguka-Rwakishaya E et al. The influence of energy intake on some blood biochemical parameters in Scottish Blackface sheep infected with Trypanosoma congolense. 1999 Vet. Parasitol. pmid:10435787
Phiri IK et al. The serum glucose and beta-hydroxybutyrate levels in sheep with experimental Fasciola hepatica and Fasciola gigantica infection. 2007 Vet. Parasitol. pmid:17011709
Stear MJ et al. The influence of relative resistance and urea-supplementation on deliberate infection with Teladorsagia circumcincta during winter. 2000 Vet. Parasitol. pmid:11078943
Katunguka-Rwakishaya E The influence of dietary protein on some blood biochemical parameters in Scottish blackface sheep experimentally infected with Trypanosoma congolense. 1997 Vet. Parasitol. pmid:9066068
Ho CF et al. Ketone bodies upregulate endothelial connexin 43 (Cx43) gap junctions. 2013 Vet. J. pmid:24210276
McArt JA et al. Elevated non-esterified fatty acids and β-hydroxybutyrate and their association with transition dairy cow performance. 2013 Vet. J. pmid:24054909
Seifi HA et al. Metabolic predictors of post-partum disease and culling risk in dairy cattle. 2011 Vet. J. pmid:20457532
Holtenius K et al. Metabolic parameters and blood leukocyte profiles in cows from herds with high or low mastitis incidence. 2004 Vet. J. pmid:15158210
Kamgarpour R et al. Post partum subclinical hypocalcaemia and effects on ovarian function and uterine involution in a dairy herd. 1999 Vet. J. pmid:10409418
Aroch I et al. A retrospective study of serum β-hydroxybutyric acid in 215 ill cats: clinical signs, laboratory findings and diagnoses. 2012 Vet. J. pmid:21316992
Vömel T et al. Phagocytosis of erythrocyte membranes (white ghosts) from different species by the isolated perfused rat liver. 1985 Vet. Immunol. Immunopathol. pmid:4035981
Hoeben D et al. Elevated levels of beta-hydroxybutyric acid in periparturient cows and in vitro effect on respiratory burst activity of bovine neutrophils. 1997 Vet. Immunol. Immunopathol. pmid:9336884
Saremi B et al. Bovine haptoglobin as an adipokine: serum concentrations and tissue expression in dairy cows receiving a conjugated linoleic acids supplement throughout lactation. 2012 Vet. Immunol. Immunopathol. pmid:22498004
Suriyasathaporn W et al. Beta-hydroxybutyrate levels in peripheral blood and ketone bodies supplemented in culture media affect the in vitro chemotaxis of bovine leukocytes. 1999 Vet. Immunol. Immunopathol. pmid:10438318
Hoeben D et al. In vitro effect of ketone bodies, glucocorticosteroids and bovine pregnancy-associated glycoprotein on cultures of bone marrow progenitor cells of cows and calves. 1999 Vet. Immunol. Immunopathol. pmid:10438322
Hammon DS et al. Neutrophil function and energy status in Holstein cows with uterine health disorders. 2006 Vet. Immunol. Immunopathol. pmid:16740320
Ospina PA et al. Using nonesterified fatty acids and β-hydroxybutyrate concentrations during the transition period for herd-level monitoring of increased risk of disease and decreased reproductive and milking performance. 2013 Vet. Clin. North Am. Food Anim. Pract. pmid:23809897
Dobbelaar P et al. Detection of ketosis in dairy cows by analysis of exhaled breath. 1996 Vet Q pmid:8972064
Weingart C et al. Validation of a portable hand-held whole-blood ketone meter for use in cats. 2012 Vet Clin Pathol pmid:22250845
Al-Qudah KM Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia. 2011 Vet Clin Pathol pmid:21299584
Ismail ZA et al. Metabolic profiles in goat does in late pregnancy with and without subclinical pregnancy toxemia. 2008 Vet Clin Pathol pmid:19055580
Chavko M et al. Attenuation of brain hyperbaric oxygen toxicity by fasting is not related to ketosis. 1999 Undersea Hyperb Med pmid:10372429
Ianovich VG et al. [Peculiarities of the metabolism of beta-oxybutyric acid in liver and skeletal muscles of piglets]. 1982 Sep-Oct Ukr. Biokhim. Zh. pmid:7135511
Bak JF [Diabetic ketoacedosis]. 2006 Ugeskr. Laeg. pmid:16430809
Toksoy HB et al. Serum carnitine, beta-hydroxybutyrate and ammonia levels during valproic acid therapy. 1995 Jan-Mar Turk. J. Pediatr. pmid:7732605
Ndlovu LR et al. Performance of draught cattle in communal farming areas in Zimbabwe after dry season supplementation. 1996 Trop Anim Health Prod pmid:8983135
Saeb M et al. Physiological response of dromedary camels to road transportation in relation to circulating levels of cortisol, thyroid hormones and some serum biochemical parameters. 2010 Trop Anim Health Prod pmid:19544085
Youssef MA et al. Ketosis in buffalo (Bubalus bubalis): clinical findings and the associated oxidative stress level. 2010 Trop Anim Health Prod pmid:20582718
Kafi M and Mirzaei A Effects of first postpartum progesterone rise, metabolites, milk yield, and body condition score on the subsequent ovarian activity and fertility in lactating Holstein dairy cows. 2010 Trop Anim Health Prod pmid:20140511
Norouzian MA et al. Rumen development and growth of Balouchi lambs offered alfalfa hay pre- and post-weaning. 2011 Trop Anim Health Prod pmid:21465104
Newman JC and Verdin E Ketone bodies as signaling metabolites. 2014 Trends Endocrinol. Metab. pmid:24140022
Chen CH and Chen SC The efficacy of non-lactate-generating metabolites as substrates for maintaining donor tissues. 1994 Transplantation pmid:8016884
Chen CH et al. Efficacy of organ preservation media enriched with nonlactate-generating substrate for maintaining tissue viability: a transplantation study. 1997 Transplantation pmid:9075834
Igea J et al. Evaluation of beta-oxidation parameters and mitochondrial redox state as early markers of hepatic function in hepatic transplantation. 1999 Transplant. Proc. pmid:10500662
Igea J et al. Ammonia levels as early markers of good graft revascularization in hepatic transplantation. 1999 Transplant. Proc. pmid:10500664
Kitabayashi K et al. Arterial ketone body ratio in clinical liver transplantation. 1998 Transplant. Proc. pmid:9865382
Yamaguchi M et al. Evaluation of temporary portal vein arterialization: the minimum arterialized blood flow for maintaining liver viability. 1990 Transpl. Int. pmid:2271087
Laird MD et al. Augmentation of normal and glutamate-impaired neuronal respiratory capacity by exogenous alternative biofuels. 2013 Transl Stroke Res pmid:24323418
Whisson ME et al. Quantitative study of starving platelets in a minimal medium: maintenance by acetate or plasma but not by glucose. 1993 Transfus Med pmid:8374698
Sasi P et al. Characterisation of metabolic acidosis in Kenyan children admitted to hospital for acute non-surgical conditions. 2006 Trans. R. Soc. Trop. Med. Hyg. pmid:16257025
Cahill GF and Veech RL Ketoacids? Good medicine? 2003 Trans. Am. Clin. Climatol. Assoc. pmid:12813917
Ally AI et al. Trimethyltin as a selective adrenal chemosympatholytic agent in vivo: effect precedes both clinical and histopathological evidence of toxicity. 1986 Toxicology pmid:3726895
Sato T et al. Effect of pravastatin on plasma ketone bodies in diabetics with hypercholesterolemia. 1998 Tohoku J. Exp. Med. pmid:9710942
Lomas AJ et al. Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)/collagen hybrid scaffolds for tissue engineering applications. 2013 Tissue Eng Part C Methods pmid:23281705
Dobbelaar P et al. [Detection of hyperketonemia with the aid of monitoring milk production and two milk tests]. 1998 Tijdschr Diergeneeskd pmid:9537097
Bijlsma JG and Counotte GH [The effect of feeding mangel-wurzels on blood beta-hydroxybutyrate level of milk-producing cows]. 1992 Tijdschr Diergeneeskd pmid:1440545
Martin R et al. [Relationships between different parameters for the evaluation of the energy balance and the differential cell count in milk from cows with healthy udders]. 2012 Tierarztl Prax Ausg G Grosstiere Nutztiere pmid:22911228