(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Sheep Diseases D012757 10 associated lipids
Stomach Diseases D013272 7 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Seifi HA et al. Metabolic predictors of post-partum disease and culling risk in dairy cattle. 2011 Vet. J. pmid:20457532
Morey SD et al. Effects of encapsulated niacin on metabolism and production of periparturient dairy cows. 2011 J. Dairy Sci. pmid:21943760
Yu HY et al. Clinical utility of Abbott Precision Xceed Pro® ketone meter in diabetic patients. 2011 Pediatr Diabetes pmid:22034832
Arora S et al. Point-of-care beta-hydroxybutyrate testing for assessing diabetic ketoacidosis severity prior to treatment in the emergency department. 2011 Diabetes Res. Clin. Pract. pmid:21955959
Ivarsson N et al. AICAR reverses ketone body mediated insulin resistance in isolated oxidative muscle. 2011 Biochem. Biophys. Res. Commun. pmid:21982775
Samala R et al. The ketogenic diet changes metabolite levels in hippocampal extracellular fluid. 2011 Neurochem. Int. pmid:21070829
Otis JP et al. Cholesterol and lipoprotein dynamics in a hibernating mammal. 2011 PLoS ONE pmid:22195001
Lu J et al. Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. 2011 Clin. Chim. Acta pmid:21036159
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Conway VD et al. Role of ribose deficit in rat testicular metabolism under conditions of overtraining. 2011 Bull. Exp. Biol. Med. pmid:22235407
Tanaka K et al. Cell growth and P(3HB) accumulation from CO2 of a carbon monoxide-tolerant hydrogen-oxidizing bacterium, Ideonella sp. O-1. 2011 Appl. Microbiol. Biotechnol. pmid:21695533
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Numis AL et al. The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. 2011 Epilepsy Res. pmid:21700429
Liu F et al. Metabolic engineering of Aeromonas hydrophila 4AK4 for production of copolymers of 3-hydroxybutyrate and medium-chain-length 3-hydroxyalkanoate. 2011 Bioresour. Technol. pmid:21680176
Li XB et al. Renal function of dairy cows with subclinical ketosis. 2011 Vet. Rec. pmid:21672951
Deng-Bryant Y et al. Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury. 2011 J. Neurotrauma pmid:21635175
Ruprechter G et al. Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes. 2011 Acta Vet. Scand. pmid:21635772
Harris DL et al. Cot-side electroencephalography monitoring is not clinically useful in the detection of mild neonatal hypoglycemia. 2011 J. Pediatr. pmid:21658714
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Collison KS et al. Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. 2011 Br. J. Nutr. pmid:21429276
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Hsu WY et al. Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21856256
Dabos KJ et al. Regional variations in the concentrations of ketone bodies in cirrhosis and hepatic encephalopathy: a study in patients with TIPSS. 2011 Liver Int. pmid:21457443
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Ruskin DN et al. A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease. 2011 Physiol. Behav. pmid:21501628
Eloqayli H et al. [2,4-(13)C]β-hydroxybutyrate metabolism in astrocytes and C6 glioblastoma cells. 2011 Neurochem. Res. pmid:21538079
Zhang Z et al. Concentrations of sodium, potassium, magnesium, and iron in the serum of dairy cows with subclinical ketosis. 2011 Biol Trace Elem Res pmid:21739162
OuYang D et al. Metabolomic profiling of serum from human pancreatic cancer patients using 1H NMR spectroscopy and principal component analysis. 2011 Appl. Biochem. Biotechnol. pmid:21505807
Ugwu CU et al. Production of (R)-3-hydroxybutyric acid by fermentation and bioconversion processes with Azohydromonas lata. 2011 Bioresour. Technol. pmid:21507620
Sevastianova K et al. Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans. 2011 Am. J. Clin. Nutr. pmid:21525193
Krogh MA et al. Latent class evaluation of a milk test, a urine test, and the fat-to-protein percentage ratio in milk to diagnose ketosis in dairy cows. 2011 J. Dairy Sci. pmid:21524525
Waddell J et al. The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies. 2011 PLoS ONE pmid:21886776
Zebeli Q et al. Perturbations of plasma metabolites correlated with the rise of rumen endotoxin in dairy cows fed diets rich in easily degradable carbohydrates. 2011 J. Dairy Sci. pmid:21524527
Norouzian MA et al. Rumen development and growth of Balouchi lambs offered alfalfa hay pre- and post-weaning. 2011 Trop Anim Health Prod pmid:21465104
Minlebaev M and Khazipov R Antiepileptic effects of endogenous beta-hydroxybutyrate in suckling infant rats. 2011 Epilepsy Res. pmid:21470827
Valergakis GE et al. Phenotypic association between energy balance indicators and reproductive performance in primiparous Holstein cows. 2011 Vet. Rec. pmid:21493532
Chmiel-Perzyńska I et al. Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. 2011 Neurotox Res pmid:20838951
Tisi DK et al. Fetal exposure to altered amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1 occurs before screening for gestational diabetes mellitus. 2011 Diabetes Care pmid:20855548
Zhang D et al. Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959534
Jankovec Z et al. Influence of physical activity on metabolic state within a 3-h interruption of continuous subcutaneous insulin infusion in patients with type 1 diabetes. 2011 Diabetes Technol. Ther. pmid:21877927
Kılıçay E et al. Preparation and characterization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy. 2011 Eur J Pharm Sci pmid:21884788
Wang Y et al. MicroRNAs in the regulation of interfacial behaviors of MSCs cultured on microgrooved surface pattern. 2011 Biomaterials pmid:21890196
González FD et al. Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. 2011 J. Vet. Sci. pmid:21897097
Lim S et al. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. 2011 PLoS ONE pmid:21931779
Zhou C et al. How useful is basal renal tubular epithelial cell vacuolization as a marker for significant hyperglycemia at autopsy? 2011 J. Forensic Sci. pmid:21827461
Stojanovic V and Ihle S Role of beta-hydroxybutyric acid in diabetic ketoacidosis: a review. 2011 Can. Vet. J. pmid:21731100
Tyzio R et al. Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate. 2011 J. Neurosci. pmid:21209187
Pifferi F et al. Mild experimental ketosis increases brain uptake of 11C-acetoacetate and 18F-fluorodeoxyglucose: a dual-tracer PET imaging study in rats. 2011 Nutr Neurosci pmid:21605500
Hart KJ et al. Effect of whole-crop pea (Pisum sativum L.) silages differing in condensed tannin content as a substitute for grass silage and soybean meal on the performance, metabolism, and carcass characteristics of lambs. 2011 J. Anim. Sci. pmid:21571892
Jackson RA et al. Energy metabolites in pre- and postpartum dairy cattle as predictors of reproductive disorders. 2011 Vet. Rec. pmid:21546407
Albano N et al. Plasma metabolite levels predict bird growth rates: A field test of model predictive ability. 2011 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:21575739
Bielohuby M et al. Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20943751
Ghanem MM and El-Deeb WM Lecithin cholesterol acyltransferase (LCAT) activity as a predictor for ketosis and parturient haemoglobinuria in Egyptian water buffaloes. 2010 Res. Vet. Sci. pmid:19682715
Alvarez-Rodríguez J et al. Metabolic and luteal function in winter-calving Spanish beef cows as affected by calf management and breed. 2010 J Anim Physiol Anim Nutr (Berl) pmid:19663981
Warren R Alcoholic lunch did not cause clinically relevant ketosis. 2010 QJM pmid:19793870
Cheng B et al. D-beta-hydroxybutyrate prevents MPP+-induced neurotoxicity in PC12 cells. 2010 Neurochem. Res. pmid:19851865
Silva-del-Río N et al. Effects of twin pregnancy and dry period feeding strategy on milk production, energy balance, and metabolic profiles in dairy cows. 2010 J. Anim. Sci. pmid:19854992
Holmgren CD et al. Energy substrate availability as a determinant of neuronal resting potential, GABA signaling and spontaneous network activity in the neonatal cortex in vitro. 2010 J. Neurochem. pmid:19943846
Butchbach ME et al. Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. 2010 Biochem. Biophys. Res. Commun. pmid:19945425
Elliott S et al. The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosis. 2010 Forensic Sci. Int. pmid:19954904
Wood CM et al. The influence of feeding and fasting on plasma metabolites in the dogfish shark (Squalus acanthias). 2010 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:19782147
Hartman AL et al. Seizure tests distinguish intermittent fasting from the ketogenic diet. 2010 Epilepsia pmid:20477852
Quiroz-Rocha GF et al. Short communication: Effect of sampling time relative to the first daily feeding on interpretation of serum fatty acid and beta-hydroxybutyrate concentrations in dairy cattle. 2010 J. Dairy Sci. pmid:20412917
Earley B et al. Effect of road transport for up to 24 hours followed by twenty-four hour recovery on live weight and physiological responses of bulls. 2010 BMC Vet. Res. pmid:20646269
Kitaoka R et al. Increased noradrenergic activity in the ventromedial hypothalamus during treadmill running in rats. 2010 J. Nutr. Sci. Vitaminol. pmid:20651459
Voulgari C and Tentolouris N The performance of a glucose-ketone meter in the diagnosis of diabetic ketoacidosis in patients with type 2 diabetes in the emergency room. 2010 Diabetes Technol. Ther. pmid:20597827
Osman MA et al. Chronic metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or both. 2010 J. Dairy Sci. pmid:20655418
Ospina PA et al. Association between the proportion of sampled transition cows with increased nonesterified fatty acids and beta-hydroxybutyrate and disease incidence, pregnancy rate, and milk production at the herd level. 2010 J. Dairy Sci. pmid:20655428
Zhou J et al. The use of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds for tarsal repair in eyelid reconstruction in the rat. 2010 Biomaterials pmid:20663550
Jeong HJ et al. The ketogenic diet suppresses the cathepsin E expression induced by kainic acid in the rat brain. 2010 Yonsei Med. J. pmid:20635438
Yamada T et al. {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20516259
Becskei C et al. Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20538900
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Kashiwaya Y et al. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. 2010 J. Biol. Chem. pmid:20529850
Thaler S et al. Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat--possible involvement of kynurenic acid. 2010 Graefes Arch. Clin. Exp. Ophthalmol. pmid:20532550
Huang ST et al. Design and synthesis of a long-wavelength latent fluorogenic substrate for salicylate hydroxylase: a useful fluorimetric indicator for analyte determination by dehydrogenase-coupled biosensors. 2010 Anal. Chem. pmid:20695438
Samiei A et al. An evaluation of beta-hydroxybutyrate in milk and blood for prediction of subclinical ketosis in dairy cows. 2010 Pol J Vet Sci pmid:20731192
Mitsuhashi Y et al. Postprandial lipid-related metabolites are altered in dogs fed dietary diacylglycerol and low glycemic index starch during weight loss. 2010 J. Nutr. pmid:20739444
Sun J et al. Production of P(3-hydroxybutyrate-co-3-hydroxyhexanoate-co-3-hydroxyoctanoate) terpolymers using a chimeric PHA synthase in recombinant Ralstonia eutropha and Pseudomonas putida. 2010 Biosci. Biotechnol. Biochem. pmid:20699558
Shozui F et al. A new beneficial mutation in pseudomonas sp. 61-3 polyhydroxyalkanoate (PHA) synthase for enhanced cellular content of 3-hydroxybutyrate-based PHA explored using its enzyme homolog as a mutation template. 2010 Biosci. Biotechnol. Biochem. pmid:20699564
Ide T Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. 2010 Biosci. Biotechnol. Biochem. pmid:20699574
Hässig M et al. [Benefit of clinical and laboratory parameters for the diagnosis of endometritis in dairy cows]. 2010 Schweiz. Arch. Tierheilkd. pmid:20814859
Bonuccelli G et al. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. 2010 Cell Cycle pmid:20818174
Eslamizad M et al. Effects of 6 times daily milking during early versus full lactation of Holstein cows on milk production and blood metabolites. 2010 J. Dairy Sci. pmid:20723679
Fürll M et al. Effect of multiple intravenous injections of butaphosphan and cyanocobalamin on the metabolism of periparturient dairy cows. 2010 J. Dairy Sci. pmid:20723690
Oliveira RA et al. Effects of feeding polyphenols from pomegranate extract on health, growth, nutrient digestion, and immunocompetence of calves. 2010 J. Dairy Sci. pmid:20723701
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Kiku Y et al. Decrease in bovine CD14 positive cells in colostrum is associated with the incidence of mastitis after calving. 2010 Vet. Res. Commun. pmid:20077004
Zhang Z et al. Evaluation of the change of serum copper and zinc concentrations of dairy cows with subclinical ketosis. 2010 Biol Trace Elem Res pmid:20101474
Ospina PA et al. Evaluation of nonesterified fatty acids and beta-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases. 2010 J. Dairy Sci. pmid:20105526
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Atshaves BP et al. High dietary fat exacerbates weight gain and obesity in female liver fatty acid binding protein gene-ablated mice. 2010 Lipids pmid:20035485
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Kaufmann TB et al. Correlations between periparturient serum concentrations of non-esterified fatty acids, beta-hydroxybutyric acid, bilirubin, and urea and the occurrence of clinical and subclinical postpartum bovine endometritis. 2010 BMC Vet. Res. pmid:20979598
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