(r)-3-hydroxybutanoic acid

(r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 2725 references associated with (r)-3-hydroxybutanoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (r)-3-hydroxybutanoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (r)-3-hydroxybutanoic acid

MeSH term MeSH ID Detail
Uremia D014511 33 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neoplasms, Experimental D009374 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Sheep Diseases D012757 10 associated lipids
Stomach Diseases D013272 7 associated lipids
Per page 10 20 50 100 | Total 185

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (r)-3-hydroxybutanoic acid

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Per page 10 20 50 100 | Total 2707
Authors Title Published Journal PubMed Link
Ghanem MM and El-Deeb WM Lecithin cholesterol acyltransferase (LCAT) activity as a predictor for ketosis and parturient haemoglobinuria in Egyptian water buffaloes. 2010 Res. Vet. Sci. pmid:19682715
Alvarez-Rodríguez J et al. Metabolic and luteal function in winter-calving Spanish beef cows as affected by calf management and breed. 2010 J Anim Physiol Anim Nutr (Berl) pmid:19663981
Seifert EL et al. Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. 2010 PLoS ONE pmid:20352092
Hajiali H et al. Preparation of a novel biodegradable nanocomposite scaffold based on poly (3-hydroxybutyrate)/bioglass nanoparticles for bone tissue engineering. 2010 J Mater Sci Mater Med pmid:20372984
Cheng B et al. D-beta-hydroxybutyrate prevents MPP+-induced neurotoxicity in PC12 cells. 2010 Neurochem. Res. pmid:19851865
Silva-del-Río N et al. Effects of twin pregnancy and dry period feeding strategy on milk production, energy balance, and metabolic profiles in dairy cows. 2010 J. Anim. Sci. pmid:19854992
Holmgren CD et al. Energy substrate availability as a determinant of neuronal resting potential, GABA signaling and spontaneous network activity in the neonatal cortex in vitro. 2010 J. Neurochem. pmid:19943846
Butchbach ME et al. Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. 2010 Biochem. Biophys. Res. Commun. pmid:19945425
Elliott S et al. The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosis. 2010 Forensic Sci. Int. pmid:19954904
Wood CM et al. The influence of feeding and fasting on plasma metabolites in the dogfish shark (Squalus acanthias). 2010 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:19782147
Hartman AL et al. Seizure tests distinguish intermittent fasting from the ketogenic diet. 2010 Epilepsia pmid:20477852
Quiroz-Rocha GF et al. Short communication: Effect of sampling time relative to the first daily feeding on interpretation of serum fatty acid and beta-hydroxybutyrate concentrations in dairy cattle. 2010 J. Dairy Sci. pmid:20412917
Zhang YQ et al. Effect of a mixture of steam-flaked corn and soybeans on health, growth, and selected blood metabolism of Holstein calves. 2010 J. Dairy Sci. pmid:20412943
Laeger T et al. Role of beta-hydroxybutyric acid in the central regulation of energy balance. 2010 Appetite pmid:20416348
Voyvoda H and Erdogan H Use of a hand-held meter for detecting subclinical ketosis in dairy cows. 2010 Res. Vet. Sci. pmid:20471047
Forslund KB et al. Low cortisol levels in blood from dairy cows with ketosis: a field study. 2010 Acta Vet. Scand. pmid:20487518
Gasior M et al. Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. 2010 Epilepsia pmid:20491877
Lucidi P et al. Mechanisms of insulin resistance after insulin-induced hypoglycemia in humans: the role of lipolysis. 2010 Diabetes pmid:20299466
Westerbacka J et al. Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. 2010 Gastroenterology pmid:20600015
Voulgari C and Tentolouris N The performance of a glucose-ketone meter in the diagnosis of diabetic ketoacidosis in patients with type 2 diabetes in the emergency room. 2010 Diabetes Technol. Ther. pmid:20597827
Osman MA et al. Chronic metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or both. 2010 J. Dairy Sci. pmid:20655418
Ospina PA et al. Association between the proportion of sampled transition cows with increased nonesterified fatty acids and beta-hydroxybutyrate and disease incidence, pregnancy rate, and milk production at the herd level. 2010 J. Dairy Sci. pmid:20655428
Zhou J et al. The use of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) scaffolds for tarsal repair in eyelid reconstruction in the rat. 2010 Biomaterials pmid:20663550
Jeong HJ et al. The ketogenic diet suppresses the cathepsin E expression induced by kainic acid in the rat brain. 2010 Yonsei Med. J. pmid:20635438
Yamada T et al. {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20516259
Becskei C et al. Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20538900
Veldhorst MA et al. Presence or absence of carbohydrates and the proportion of fat in a high-protein diet affect appetite suppression but not energy expenditure in normal-weight human subjects fed in energy balance. 2010 Br. J. Nutr. pmid:20565999
Kashiwaya Y et al. A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat. 2010 J. Biol. Chem. pmid:20529850
Thaler S et al. Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat--possible involvement of kynurenic acid. 2010 Graefes Arch. Clin. Exp. Ophthalmol. pmid:20532550
Seong SH et al. L-carnitine-supplemented parenteral nutrition improves fat metabolism but fails to support compensatory growth in premature Korean infants. 2010 Nutr Res pmid:20534325
Zhang C et al. Folate-mediated poly(3-hydroxybutyrate-co-3-hydroxyoctanoate) nanoparticles for targeting drug delivery. 2010 Eur J Pharm Biopharm pmid:20472060
Kelly AK et al. Repeatability of feed efficiency, carcass ultrasound, feeding behavior, and blood metabolic variables in finishing heifers divergently selected for residual feed intake. 2010 J. Anim. Sci. pmid:20525931
Zeugswetter F et al. Efficacy of plasma beta-hydroxybutyrate concentration as a marker for diabetes mellitus in acutely sick cats. 2010 J. Feline Med. Surg. pmid:20117951
Mitsuhashi Y et al. Postprandial lipid-related metabolites are altered in dogs fed dietary diacylglycerol and low glycemic index starch during weight loss. 2010 J. Nutr. pmid:20739444
Fisher AD et al. The effects of 12, 30, or 48 hours of road transport on the physiological and behavioral responses of sheep. 2010 J. Anim. Sci. pmid:20154169
Sun J et al. Production of P(3-hydroxybutyrate-co-3-hydroxyhexanoate-co-3-hydroxyoctanoate) terpolymers using a chimeric PHA synthase in recombinant Ralstonia eutropha and Pseudomonas putida. 2010 Biosci. Biotechnol. Biochem. pmid:20699558
Samoilova M et al. Chronic in vitro ketosis is neuroprotective but not anti-convulsant. 2010 J. Neurochem. pmid:20163521
Shozui F et al. A new beneficial mutation in pseudomonas sp. 61-3 polyhydroxyalkanoate (PHA) synthase for enhanced cellular content of 3-hydroxybutyrate-based PHA explored using its enzyme homolog as a mutation template. 2010 Biosci. Biotechnol. Biochem. pmid:20699564
Song H et al. Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20179248
Ide T Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. 2010 Biosci. Biotechnol. Biochem. pmid:20699574
Ramnanan CJ et al. Molecular characterization of insulin-mediated suppression of hepatic glucose production in vivo. 2010 Diabetes pmid:20185816
Hässig M et al. [Benefit of clinical and laboratory parameters for the diagnosis of endometritis in dairy cows]. 2010 Schweiz. Arch. Tierheilkd. pmid:20814859
Bonuccelli G et al. Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism. 2010 Cell Cycle pmid:20818174
Eslamizad M et al. Effects of 6 times daily milking during early versus full lactation of Holstein cows on milk production and blood metabolites. 2010 J. Dairy Sci. pmid:20723679
Fürll M et al. Effect of multiple intravenous injections of butaphosphan and cyanocobalamin on the metabolism of periparturient dairy cows. 2010 J. Dairy Sci. pmid:20723690
Oliveira RA et al. Effects of feeding polyphenols from pomegranate extract on health, growth, nutrient digestion, and immunocompetence of calves. 2010 J. Dairy Sci. pmid:20723701
Meier S et al. Effects of divergent Holstein-Friesian strain and diet on diurnal patterns of plasma metabolites and hormones. 2010 J. Dairy Res. pmid:20822560
Ospina PA et al. Evaluation of nonesterified fatty acids and beta-hydroxybutyrate in transition dairy cattle in the northeastern United States: Critical thresholds for prediction of clinical diseases. 2010 J. Dairy Sci. pmid:20105526
Zhang XX and Rainey PB Bet hedging in the underworld. 2010 Genome Biol. pmid:21062509
Soberon F et al. Effects of increased milking frequency on metabolism and mammary cell proliferation in Holstein dairy cows. 2010 J. Dairy Sci. pmid:20105528
Henderson DW and Schlesinger DP Use of a point-of-care beta-hydroxybutyrate sensor for detection of ketonemia in dogs. 2010 Can. Vet. J. pmid:21119867
Karcagi RG et al. Milk production, peripartal liver triglyceride concentration and plasma metabolites of dairy cows fed diets supplemented with calcium soaps or hydrogenated triglycerides of palm oil. 2010 J. Dairy Res. pmid:20030903
Kirmse K et al. GABA depolarizes immature neocortical neurons in the presence of the ketone body ß-hydroxybutyrate. 2010 J. Neurosci. pmid:21106838
Atshaves BP et al. High dietary fat exacerbates weight gain and obesity in female liver fatty acid binding protein gene-ablated mice. 2010 Lipids pmid:20035485
Stasiak P et al. In vivo assessment of parenteral formulations of oligo(3-hydroxybutyric Acid) conjugates with the model compound Ibuprofen. 2010 AAPS PharmSciTech pmid:21088943
Jaakson H et al. Field trial on glucose-induced insulin and metabolite responses in Estonian Holstein and Estonian Red dairy cows in two herds. 2010 Acta Vet. Scand. pmid:20089161
Tetrick MA et al. Blood D-(-)-3-hydroxybutyrate concentrations after oral administration of trioctanoin, trinonanoin, or tridecanoin to newborn rhesus monkeys (Macaca mulatta). 2010 Comp. Med. pmid:21262136
Rivera N et al. Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs. 2010 J. Clin. Invest. pmid:21084754
Wagner SA and Schimek DE Evaluation of the effect of bolus administration of 50% dextrose solution on measures of electrolyte and energy balance in postpartum dairy cows. 2010 Am. J. Vet. Res. pmid:20807148
Kalaitzakis E et al. Clinicopathological evaluation of downer dairy cows with fatty liver. 2010 Can. Vet. J. pmid:20808573
Morgante M et al. Preliminary study on metabolic profile of pregnant and non-pregnant ewes with high or low degree of behavioral lateralization. 2010 Anim. Sci. J. pmid:21108694
McGuire LP et al. Determining feeding state and rate of mass change in insectivorous bats using plasma metabolite analysis. 2009 Nov-Dec Physiol. Biochem. Zool. pmid:19799521
Di Tommaso M et al. Evaluation of a portable meter to measure ketonemia and comparison with ketonuria for the diagnosis of canine diabetic ketoacidosis. 2009 May-Jun J. Vet. Intern. Med. pmid:19645834
Schreurs M et al. Soraphen, an inhibitor of the acetyl-CoA carboxylase system, improves peripheral insulin sensitivity in mice fed a high-fat diet. 2009 Diabetes Obes Metab pmid:19519866
Li Z et al. Synthesis, characterization and biocompatibility of biodegradable elastomeric poly(ether-ester urethane)s Based on Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) and Poly(ethylene glycol) via melting polymerization. 2009 J Biomater Sci Polym Ed pmid:19520007
Yu BY et al. Modulating the activities of human mesenchymal stem cells (hMSCs) and C3A/HepG2 hepatoma cells by modifying the surface characteristics of poly(3-hydroxybutyrate-co-3-hydroxyhexnoate) (PHBHHx). 2009 J Biomater Sci Polym Ed pmid:19520012
Ye C et al. PHB/PHBHHx scaffolds and human adipose-derived stem cells for cartilage tissue engineering. 2009 Biomaterials pmid:19481254
Dasarathy S et al. Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19571235
Young DC et al. Synthesis of dideoxymycobactin antigens presented by CD1a reveals T cell fine specificity for natural lipopeptide structures. 2009 J. Biol. Chem. pmid:19605355
Shen F et al. Surface bio-modification of poly(hydroxybutyrate-co-hydroxyhexanoate) and its aging effect. 2009 Colloids Surf B Biointerfaces pmid:19559576
Liepinsh E et al. Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats. 2009 Br. J. Pharmacol. pmid:19594753
Kotronen A et al. Liver fat and lipid oxidation in humans. 2009 Liver Int. pmid:19602132
Tyo KE et al. Stabilized gene duplication enables long-term selection-free heterologous pathway expression. 2009 Nat. Biotechnol. pmid:19633654
Cureton KJ et al. Dietary quercetin supplementation is not ergogenic in untrained men. 2009 J. Appl. Physiol. pmid:19679747
Tanadchangsaeng N et al. Identification, biosynthesis, and characterization of polyhydroxyalkanoate copolymer consisting of 3-hydroxybutyrate and 3-hydroxy-4-methylvalerate. 2009 Biomacromolecules pmid:19681605
Moyes KM et al. Identification of potential markers in blood for the development of subclinical and clinical mastitis in dairy cattle at parturition and during early lactation. 2009 J. Dairy Sci. pmid:19841204
Zhang ZG et al. Measurement of milk D-3-hydroxybutyrate with a simple UV spectrophotometer method: an alternative assay method. 2009 Pol J Vet Sci pmid:20169934
Larsen M and Kristensen NB Effect of abomasal glucose infusion on splanchnic and whole-body glucose metabolism in periparturient dairy cows. 2009 J. Dairy Sci. pmid:19233800
Ametaj BN et al. Feeding high proportions of barley grain in a total mixed ration perturbs diurnal patterns of plasma metabolites in lactating dairy cows. 2009 J. Dairy Sci. pmid:19233801
Duffield TF et al. Impact of hyperketonemia in early lactation dairy cows on health and production. 2009 J. Dairy Sci. pmid:19164667
Osborne VR et al. Effects of supplementing glycerol and soybean oil in drinking water on feed and water intake, energy balance, and production performance of periparturient dairy cows. 2009 J. Dairy Sci. pmid:19164682
Chen Z et al. Block poly(ester-urethane)s based on poly(3-hydroxybutyrate-co-4-hydroxybutyrate) and poly(3-hydroxyhexanoate-co-3-hydroxyoctanoate). 2009 Biomaterials pmid:19167751
Hu ZG et al. Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats. 2009 Ann. Clin. Lab. Sci. pmid:19201746
Dai ZW et al. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) as an injectable implant system for prevention of post-surgical tissue adhesion. 2009 Biomaterials pmid:19269028
Yu F et al. Effect of comonomer-unit compositional distribution on thermal and crystallization behavior of bacterial poly[(3-hydroxybutyrate)-co-(3-mercaptopropionate)]. 2009 Macromol Biosci pmid:19274617
Zhang X et al. Application of (R)-3-hydroxyalkanoate methyl esters derived from microbial polyhydroxyalkanoates as novel biofuels. 2009 Biomacromolecules pmid:19249855
Yamada M et al. Microbial production of lactate-enriched poly[(R)-lactate-co-(R)-3-hydroxybutyrate] with novel thermal properties. 2009 Biomacromolecules pmid:19249863
Tassoul MD and Shaver RD Effect of a mixture of supplemental dietary plant essential oils on performance of periparturient and early lactation dairy cows. 2009 J. Dairy Sci. pmid:19307655
Maki KC et al. Postprandial metabolism with 1,3-diacylglycerol oil versus equivalent intakes of long-chain and medium-chain triacylglycerol oils. 2009 Nutrition pmid:19217260
Takanashi M et al. Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1. 2009 Antonie Van Leeuwenhoek pmid:19219638
Page KA et al. Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia. 2009 Diabetes pmid:19223595
Verrier D et al. Physiological response to extreme fasting in subantarctic fur seal (Arctocephalus tropicalis) pups: metabolic rates, energy reserve utilization, and water fluxes. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19776248
Bortolotti M et al. High protein intake reduces intrahepatocellular lipid deposition in humans. 2009 Am. J. Clin. Nutr. pmid:19710199
Camara Y et al. UCP3 expression in liver modulates gene expression and oxidative metabolism in response to fatty acids, and sensitizes mitochondria to permeability transition. 2009 Cell. Physiol. Biochem. pmid:19710539
Balietti M et al. A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes. 2009 Ann. N. Y. Acad. Sci. pmid:19723079
Arlt S et al. Efficacy of homeopathic remedies as prophylaxis of bovine endometritis. 2009 J. Dairy Sci. pmid:19762811
Goldhawk C et al. Prepartum feeding behavior is an early indicator of subclinical ketosis. 2009 J. Dairy Sci. pmid:19762814
Coleman J et al. The influence of genetic selection and feed system on the reproductive performance of spring-calving dairy cows within future pasture-based production systems. 2009 J. Dairy Sci. pmid:19762844
Hiss S et al. Short communication: Relationship between metabolic status and the milk concentrations of haptoglobin and lactoferrin in dairy cows during early lactation. 2009 J. Dairy Sci. pmid:19700704
Stasiak P et al. Characterisation of a novel conjugate of ibuprofen with 3-hydroxybutyric acid oligomers. 2009 J. Pharm. Pharmacol. pmid:19703357