2-Methylbutanoic acid

2-Methylbutanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Binding (Molecular Function), Oxidation, isoleucine catabolic process, Anabolism and physiological aspects. 2-methylbutanoic acid often locates in Membrane, soluble and host. The associated genes with 2-Methylbutanoic acid are Homologous Gene, Genome, NKS1 gene, HM13 gene and ACSM1 gene. The related lipids are Fatty Acids, Butyric Acids, branched chain fatty acid, Propionate and 2-methylvalerate.

Cross Reference

Introduction

To understand associated biological information of 2-Methylbutanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Methylbutanoic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Methylbutanoic acid

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 2-Methylbutanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Methylbutanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 2-Methylbutanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2-Methylbutanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 2-Methylbutanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2-Methylbutanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2-Methylbutanoic acid

Download all related citations
Per page 10 20 50 100 | Total 140
Authors Title Published Journal PubMed Link
pmid:
Wang F et al. Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase. 2015 ACS Chem. Biol. pmid:25581064
Vallejos J et al. Butane-1,4-diyl bis-(pyridine-3-carboxyl-ate). 2012 Acta Crystallogr Sect E Struct Rep Online pmid:22807836
Fun HK et al. Absolute configuration of odorine. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588760
Vitali B et al. An in vitro evaluation of the effect of probiotics and prebiotics on the metabolic profile of human microbiota. 2012 Anaerobe pmid:22579985
Siebert TE et al. Stable isotope dilution analysis of wine fermentation products by HS-SPME-GC-MS. 2005 Anal Bioanal Chem pmid:15660221
Hutchinson CR et al. Aspects of the biosynthesis of non-aromatic fungal polyketides by iterative polyketide synthases. 2000 Antonie Van Leeuwenhoek pmid:11386351
Serrazanetti DI et al. Acid stress-mediated metabolic shift in Lactobacillus sanfranciscensis LSCE1. 2011 Appl. Environ. Microbiol. pmid:21335381
Giotis ES et al. Role of branched-chain fatty acids in pH stress tolerance in Listeria monocytogenes. 2007 Appl. Environ. Microbiol. pmid:17114323
Ganesan B et al. Identification of the leucine-to-2-methylbutyric acid catabolic pathway of Lactococcus lactis. 2006 Appl. Environ. Microbiol. pmid:16751541
Singh VK et al. Insertional inactivation of branched-chain alpha-keto acid dehydrogenase in Staphylococcus aureus leads to decreased branched-chain membrane fatty acid content and increased susceptibility to certain stresses. 2008 Appl. Environ. Microbiol. pmid:18689519
Tanner RS and Wolfe RS Nutritional requirements of Methanomicrobium mobile. 1988 Appl. Environ. Microbiol. pmid:3377488
Annous BA et al. Critical role of anteiso-C15:0 fatty acid in the growth of Listeria monocytogenes at low temperatures. 1997 Appl. Environ. Microbiol. pmid:9327552
Suarez de Mata Z et al. Propionyl-CoA condensing enzyme from Ascaris muscle mitochondria. I. Isolation and characterization of multiple forms. 1991 Arch. Biochem. Biophys. pmid:1990976
Suarez de Mata Z et al. 2-Methylacetoacetyl-coenzyme A reductase from Ascaris muscle: purification and properties. 1983 Arch. Biochem. Biophys. pmid:6357089
Jones SL et al. Correlation of long-range membrane order with temperature-dependent growth characteristics of parent and a cold-sensitive, branched-chain-fatty-acid-deficient mutant of Listeria monocytogenes. 2002 Arch. Microbiol. pmid:11907677
Kaler G et al. Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. 2006 Biochem. Biophys. Res. Commun. pmid:17094945
Mamer OA et al. Demonstration of a new mammalian isoleucine catabolic pathway yielding an Rseries of metabolites. 1976 Biochem. J. pmid:1016232
Meehan MJ et al. FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF. 2011 Biochemistry pmid:21069965
Kaneda T Stereoselectivity in the 2-methylbutyrate incorporation into anteiso fatty acids in Bacillus subtilis mutants. 1988 Biochim. Biophys. Acta pmid:3129014
Toyama T et al. Isolation and characterization of a novel 2-sec-butylphenol-degrading bacterium Pseudomonas sp. strain MS-1. 2010 Biodegradation pmid:19705287
Prakash S et al. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. 2011 Biologics pmid:21847343
Wang J et al. Study on pharmacokinetics and tissue distribution of pteryxin in mice by ultra-pressure liquid chromatography with tandem mass spectrometry. 2012 Biomed. Chromatogr. pmid:22102402
Tokitomo Y et al. Odor-active constituents in fresh pineapple (Ananas comosus [L.] Merr.) by quantitative and sensory evaluation. 2005 Biosci. Biotechnol. Biochem. pmid:16041138
Batstone DJ et al. Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate. 2003 Biotechnol. Bioeng. pmid:12966576
Pind PF et al. Dynamics of the anaerobic process: effects of volatile fatty acids. 2003 Biotechnol. Bioeng. pmid:12701145
Knebel LA et al. 2-Methylbutyrylglycine induces lipid oxidative damage and decreases the antioxidant defenses in rat brain. 2012 Brain Res. pmid:22967964
El Amine Dib M et al. Characterization of volatile compounds of Daucus crinitus Desf. Headspace Solid Phase Microextraction as alternative technique to Hydrodistillation. 2010 Chem Cent J pmid:20858266
Sellami HK et al. Composition of the essential oils in various organs at different developmental stages of Ammi visnaga (L.) Lam. from Tunisia. 2011 Chem. Biodivers. pmid:22083912
Ortet R et al. Composition and biological properties of the volatile oil of Artemisia gorgonum Webb. 2010 Chem. Biodivers. pmid:20491086
Tabanca N et al. Bioactive constituents from Turkish Pimpinella species. 2005 Chem. Biodivers. pmid:17191975
Korman SH et al. 2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation. 2005 Clin. Chem. pmid:15615815
Bachmann C et al. Short chain fatty acids in plasma and brain: quantitative determination by gas chromatography. 1979 Clin. Chim. Acta pmid:487569
Kumar PA et al. Identification of fruity aroma-producing compounds from Chryseobacterium sp. isolated from the Western Ghats, India. 2011 Curr. Microbiol. pmid:21667308
Hauck T et al. Metabolism of ethyl tiglate in apple fruits leads to the formation of small amounts of (R)-ethyl 2-methylbutanoate. 2000 Enantiomer pmid:11143814
Rezanka T et al. Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces. 2011 Environ. Microbiol. pmid:21450004
Wyss C Fatty acids synthesized by oral treponemes in chemically defined media. 2007 FEMS Microbiol. Lett. pmid:17229060
Novák J et al. Nitrogen regulation of fatty acids and avermectins biosynthesis in Streptomyces avermitilis. 1992 FEMS Microbiol. Lett. pmid:1612418
Danyluk MD et al. Prevalence, concentration, spoilage, and mitigation of Alicyclobacillus spp. in tropical and subtropical fruit juice concentrates. 2011 Food Microbiol. pmid:21356453
Seenivasan A et al. Microbial production and biomedical applications of lovastatin. 2008 Indian J Pharm Sci pmid:21369428
Kitazono M et al. Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. 2001 Int. J. Cancer pmid:11149411
Inoue H et al. Histone deacetylase inhibitors sensitize human colonic adenocarcinoma cell lines to TNF-related apoptosis inducing ligand-mediated apoptosis. 2002 Int. J. Mol. Med. pmid:11956660
Kato T et al. Survey of conformational role of ester bonds in a cyclic depsipeptide. Study on cyclo(-L-Ala-L-Hmb-)2 by energy calculation and NMR spectroscopy. 1992 Int. J. Pept. Protein Res. pmid:1399269
Savant DV et al. Methanobrevibacter acididurans sp. nov., a novel methanogen from a sour anaerobic digester. 2002 Int. J. Syst. Evol. Microbiol. pmid:12148611
Suzuki D et al. Desulfovibrio butyratiphilus sp. nov., a Gram-negative, butyrate-oxidizing, sulfate-reducing bacterium isolated from an anaerobic municipal sewage sludge digester. 2010 Int. J. Syst. Evol. Microbiol. pmid:19654341
Goldstein EJ and Arias IM Interaction of ligandin with radiographic contrast media. 1976 Nov-Dec Invest Radiol pmid:1002414
Velasco-Negueruela A et al. Analysis by gas chromatography-mass spectrometry of the essential oil from the aerial parts of Pimpinella junoniae Ceb. & Ort., gathered in La Gomera, Canary Islands, Spain. 2003 J Chromatogr A pmid:14518782
Hajhashemi V et al. Anti-inflammatory and analgesic properties of Heracleum persicum essential oil and hydroalcoholic extract in animal models. 2009 J Ethnopharmacol pmid:19467316
Huynh LK et al. Kinetic modeling of methyl butanoate in shock tube. 2008 J Phys Chem A pmid:19035670
El-Nahas AM et al. Enthalpies of formation, bond dissociation energies and reaction paths for the decomposition of model biofuels: ethyl propanoate and methyl butanoate. 2007 J Phys Chem A pmid:17286391