Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Seizures D012640 87 associated lipids
Dermatitis D003872 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Purine-Pyrimidine Metabolism, Inborn Errors D011686 5 associated lipids
Vitamin B Deficiency D014804 4 associated lipids
Toxocariasis D014120 3 associated lipids
Dihydropyrimidine Dehydrogenase Deficiency D054067 1 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

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Authors Title Published Journal PubMed Link
Hyun MY et al. catena-Poly[[tetra-aqua-[trans-1,2-bis-(4-pyrid-yl)ethene-κN:N']nickel(II)] dinitrate]. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21753926
Langley SK et al. Structure, magnetism and theory of a family of nonanuclear Cu(II)5Ln(III)4-triethanolamine clusters displaying single-molecule magnet behaviour. 2011 Chemistry pmid:21732432
St Michael F et al. Investigating the candidacy of lipopolysaccharide-based glycoconjugates as vaccines to combat Mannheimia haemolytica. 2011 Glycoconj. J. pmid:21701793
Stefanucci A et al. Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control. 2011 Int J Mol Sci pmid:21686155
Ferrer Flegeau E et al. Autocatalysis for C-H bond activation by ruthenium(II) complexes in catalytic arylation of functional arenes. 2011 J. Am. Chem. Soc. pmid:21604765
Xu M et al. (E)-2-(4-tert-Butyl-phen-yl)-1-(4-chloro-1-ethyl-3-methyl-1H-pyrazol-5-yl)-2-cyano-ethenyl 2,2-dimethyl-propano-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589554
Gu XB et al. tert-Butyl 6-amino-3,4-dihydro-2H-1,4-benzoxazine-4-carboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589552
Lohier JF et al. tert-Butyl 6-bromo-1,4-dimethyl-9H-carbazole-9-carboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588291
Gu XB tert-Butyl 6-acetamido-3,4-dihydro-2H-1,4-benzoxazine-4-carboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21587577
Chen XD et al. Aqua-(1,10-phenanthroline-κN,N')bis-(trimethyl-acetato)-κO,O';κO-cobalt(II). 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21583436
Thoss M et al. (R)-Di-tert-butyl 1,1'-binaphthyl-2,2'-dicarboxyl-ate. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21581860
Xu WJ et al. N-{N-[N-(1,1-Dimethyl-ethoxy-carbon-yl)-l-leuc-yl]-N-methyl-l-leuc-yl}-N-methyl-l-leucine benzyl ester. 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21581037
Ozair LN et al. Tetra-kis(μ(2)-2,2-dimethyl-propanoato-κO,O')bis-[(pyridine-κN)copper(II)]: a monoclinic polymorph. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579064
Sun Y et al. μ(3)-Oxido-hexa-μ(2)-pivalato-tris[(methanol-κO)cobalt(III)] chloride. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21578144
Berkovitch-Luria G et al. Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways. 2012 Invest New Drugs pmid:21509470
Langley SK et al. A high nuclearity mixed valence {Mn32} complex. 2011 Chem. Commun. (Camb.) pmid:21503362
Ovcharenko VI et al. "Jumping crystals": oxygen-evolving metal-nitroxide complexes. 2011 Inorg Chem pmid:21491890
Rezanka T et al. Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces. 2011 Environ. Microbiol. pmid:21450004
Walling HW and Swick BL Update on the management of chronic eczema: new approaches and emerging treatment options. 2010 Clin Cosmet Investig Dermatol pmid:21437065
Wexler BC Corticotropin stimulation of hypertensive rats with and without arteriosclerosis. 1978 Arch. Pathol. Lab. Med. pmid:214053
Illg T et al. Continuous synthesis of tert-butyl peroxypivalate using a single-channel microreactor equipped with orifices as emulsification units. 2011 ChemSusChem pmid:21302363
Tobisu M et al. Nickel-catalyzed reductive cleavage of aryl-oxygen bonds in alkoxy- and pivaloxyarenes using hydrosilanes as a mild reducing agent. 2011 Chem. Commun. (Camb.) pmid:21264420
Kotzabasaki V et al. Hexametallic manganese clusters with bulky derivatised salicylaldoximes. 2011 Dalton Trans pmid:21249253
Shoman ME et al. Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties. 2011 J. Med. Chem. pmid:21247168
Schmidt J et al. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. 2011 J. Biol. Chem. pmid:21220428
Overgaard J et al. Tetra-kis(μ-pivalato-κO:O')bis-[(2-methyl-pyridine-κN)iron(II)](Fe-Fe). 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21201879
Villa G et al. Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. 2010 Mol Pain pmid:21143950
Xu S et al. Transport of L-carnitine in human corneal and conjunctival epithelial cells. 2010 Mol. Vis. pmid:21045919
Abbas G et al. Series of isostructural planar lanthanide complexes [Ln(III)4(mu3-OH)2(mdeaH)2(piv)8] with single molecule magnet behavior for the Dy4 analogue. 2010 Inorg Chem pmid:20704320
Jarenmark M et al. Unsymmetrical dizinc complexes as models for the active sites of phosphohydrolases. 2010 Dalton Trans pmid:20683537
Rousseaux S et al. Investigation of the mechanism of C(sp3)-H bond cleavage in Pd(0)-catalyzed intramolecular alkane arylation adjacent to amides and sulfonamides. 2010 J. Am. Chem. Soc. pmid:20681702
Sobkowski M et al. Stereochemistry of internucleotide bond formation by the H-phosphonate method. 5. The role of Brønsted and H-bonding base catalysis in ribonucleoside H-phosphonate condensation-chemical and stereochemical consequences. 2010 Nucleosides Nucleotides Nucleic Acids pmid:20661816
Nakajima Y et al. Detection of pivaloylcarnitine in pediatric patients with hypocarnitinemia after long-term administration of pivalate-containing antibiotics. 2010 Tohoku J. Exp. Med. pmid:20651467
Govindan S et al. Ca(2+) signalling by P2Y receptors in cultured rat aortic smooth muscle cells. 2010 Br. J. Pharmacol. pmid:20649593
Will KW et al. Quantification and evidence for mechanically metered release of pygidial secretions in formic acid-producing carabid beetles. 2010 J. Insect Sci. pmid:20575743
Rumschinski P et al. Set-base dynamical parameter estimation and model invalidation for biochemical reaction networks. 2010 BMC Syst Biol pmid:20500862
Lyubinetsky I et al. Adsorption states and mobility of trimethylacetic acid molecules on reduced TiO(2)(110) surface. 2010 Phys Chem Chem Phys pmid:20490397
Zhao XQ et al. Synthesis, structures and magnetic properties of a series of 3d-4f tetranuclear Co(II)â‚‚Ln(III)â‚‚ cubanes. 2010 Dalton Trans pmid:20401413
Liu TF et al. An alcoholysis route to a Cu16 cluster, and the influence of the alcohol. 2010 Dalton Trans pmid:20354607
Cox AD et al. Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: chemical strategies to prepare glycoconjugates with good carbohydrate loading. 2010 Glycoconj. J. pmid:20340043
Shimasaki T et al. Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds. 2010 Angew. Chem. Int. Ed. Engl. pmid:20229558
Rohwerder T and Müller RH Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon. 2010 Microb. Cell Fact. pmid:20184738
Fagerholm AE et al. Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C. 2010 Mar Drugs pmid:20161975
Andó RD et al. A comparative analysis of the activity of ligands acting at P2X and P2Y receptor subtypes in models of neuropathic, acute and inflammatory pain. 2010 Br. J. Pharmacol. pmid:20136836
Gupta SK et al. Recent advances in pharmacotherapy of glaucoma. 2008 Indian J Pharmacol pmid:20040958
Kotal A et al. Ultrasound-induced in situ formation of coordination organogels from isobutyric acids and zinc oxide nanoparticles. 2010 Langmuir pmid:20020763
Wurm A et al. Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells. 2010 J. Neurochem. pmid:20002522
Alborés P and Rentschler E A Co36 cluster assembled from the reaction of cobalt pivalate with 2,3-dicarboxypyrazine. 2009 Angew. Chem. Int. Ed. Engl. pmid:19890926
Boeer AB et al. Linkage isomerism and spin frustration in heterometallic rings: synthesis, structural characterization, and magnetic and EPR spectroscopic studies of Cr(7)Ni, Cr(6)Ni(2), and Cr(7)Ni(2) rings templated about imidazolium cations. 2009 Chemistry pmid:19859922
Rao ChB et al. An efficient protocol for alcohol protection under solvent- and catalyst-free conditions. 2009 J. Org. Chem. pmid:19839567