MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pivalic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhou Q et al. | In situ generation of palladium nanoparticles: ligand-free palladium catalyzed pivalic acid assisted carbonylative Suzuki reactions at ambient conditions. | 2014 | J. Org. Chem. | pmid:24397578 |
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Ohashi R et al. | Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10525100 |
Sloan CA | Proceedings: Comparison of dexamethasone trimethylacetate and prostaglandin F-2alpha as abortifacients in the cow. | 1976 | J. Reprod. Fertil. | pmid:1255625 |
Dilks JR and Flaumenhaft R | Fluoxetine (Prozac) augments platelet activation mediated through protease-activated receptors. | 2008 | J. Thromb. Haemost. | pmid:18194419 |
Fujii R et al. | [Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients]. | 1993 | Jpn J Antibiot | pmid:8254895 |
Holme E et al. | Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. | 1989 | Lancet | pmid:2570185 |
Melegh B | Carnitine supplementation in pivampicillin treatment. | 1989 | Lancet | pmid:2572813 |
Kotal A et al. | Ultrasound-induced in situ formation of coordination organogels from isobutyric acids and zinc oxide nanoparticles. | 2010 | Langmuir | pmid:20020763 |
Ikeda M et al. | Scanning tunneling microscopy study of black dye and deoxycholic acid adsorbed on a rutile TiO2(110). | 2008 | Langmuir | pmid:18590297 |
Takahashi Y et al. | A case of sudden unexpected infant death involving a homozygotic twin with the thermolabile CPT2 variant, accompanied by rotavirus infection and treatment with an antibiotic containing pivalic acid. | 2016 | Leg Med (Tokyo) | pmid:27591533 |
Morris GS et al. | Sodium pivalate reduces cardiac carnitine content and increases glucose oxidation without affecting cardiac functional capacity. | 1995 | Life Sci. | pmid:7475977 |
Ricciolini R et al. | The effect of pivalate treatment of pregnant rats on body mass and insulin levels in the adult offspring. | 2001 | Life Sci. | pmid:11665835 |
Fagerholm AE et al. | Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C. | 2010 | Mar Drugs | pmid:20161975 |