MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pivalic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yahyaoui R et al. | [C5-carnitine false positive results in newborn screening: what is the cause?]. | 2015 | Med Clin (Barc) | pmid:24889749 |
Broderick TL et al. | Fatty acid oxidation and cardiac function in the sodium pivalate model of secondary carnitine deficiency. | 1995 | Metab. Clin. Exp. | pmid:7723673 |
Abrahamsson K et al. | Pivalic acid-induced carnitine deficiency and physical exercise in humans. | 1996 | Metab. Clin. Exp. | pmid:8969283 |
Rohwerder T and Müller RH | Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon. | 2010 | Microb. Cell Fact. | pmid:20184738 |
Villa G et al. | Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. | 2010 | Mol Pain | pmid:21143950 |
Boemer F et al. | Surprising causes of C5-carnitine false positive results in newborn screening. | 2014 | Mol. Genet. Metab. | pmid:24291264 |
Xu S et al. | Transport of L-carnitine in human corneal and conjunctival epithelial cells. | 2010 | Mol. Vis. | pmid:21045919 |
MacDiarmid SC | Betamethasone alcohol suspensions for the induction of parturition in dairy cows: a comparison with dexamethasone trimethyl acetate. | 1979 | N Z Vet J | pmid:292913 |
Shan Y et al. | Rapid acyl migration between pyrogallyl 1,2- and 1,3-dipivaloates. | 2012 | Nat Prod Commun | pmid:22545406 |
Quintas C et al. | The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues. | 2009 | Neurochem. Int. | pmid:19447154 |
Rispoli V et al. | Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert. | 2004 | Neurosci. Lett. | pmid:15036629 |
Zizzo MG et al. | Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release. | 2007 | Neuroscience | pmid:17997228 |
Andersson L et al. | Glucose concentrations in plasma and urine after glucocorticoid injection in healthy cows. | 1982 Apr-May | Nord Vet Med | pmid:6184673 |
Kumar P et al. | [131I]Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice. | 2005 | Nucl. Med. Biol. | pmid:16026712 |
Sobkowski M et al. | Stereochemistry of internucleotide bond formation by the H-phosphonate method. 5. The role of Brønsted and H-bonding base catalysis in ribonucleoside H-phosphonate condensation-chemical and stereochemical consequences. | 2010 | Nucleosides Nucleotides Nucleic Acids | pmid:20661816 |
Wu M et al. | Synthesis of 9-[1-(substituted)-3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents. | 2005 | Nucleosides Nucleotides Nucleic Acids | pmid:16438034 |
Kim D and Hong S | Palladium(II)-catalyzed direct intermolecular alkenylation of chromones. | 2011 | Org. Lett. | pmid:21797199 |
Goswami S et al. | Recognition of carboxylate anions and carboxylic acids by selenium-based new chromogenic fluorescent sensor: a remarkable fluorescence enhancement of hindered carboxylates. | 2009 | Org. Lett. | pmid:19728733 |
Murakami K et al. | Chromium-catalyzed arylmagnesiation of alkynes. | 2007 | Org. Lett. | pmid:17352489 |
Srinivas HD et al. | Enantiospecific, nickel-catalyzed cross-couplings of allylic pivalates and arylboroxines. | 2014 | Org. Lett. | pmid:24927013 |