MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pivalic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Probian C et al. | Anaerobic mineralization of quaternary carbon atoms: isolation of denitrifying bacteria on pivalic acid (2,2-dimethylpropionic acid). | 2003 | Appl. Environ. Microbiol. | pmid:12620885 |
Li C et al. | In vitro studies on the chemical reactivity of 2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester. | 2003 | Toxicol. Appl. Pharmacol. | pmid:12649042 |
Li C et al. | In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat. | 2003 | J. Pharmacol. Exp. Ther. | pmid:12649376 |
Wang SS et al. | Cleavage and deprotection of peptides on MBHA-resin with hydrogen bromide. | 1992 Sep-Oct | Int. J. Pept. Protein Res. | pmid:1335998 |
Konishi M and Hashimoto H | Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection. | 1992 | J Pharm Sci | pmid:1432617 |
Spino C et al. | A stereodivergent approach to chiral nonracemic N-protected alpha,alpha-dialkylated amino acids. | 2003 | J. Am. Chem. Soc. | pmid:14518992 |
Aromà G et al. | Synthetic and structural studies of cobalt-pivalate complexes. | 2003 | Chemistry | pmid:14562332 |
Goossen LJ and RodrÃguez N | A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction. | 2004 | Chem. Commun. (Camb.) | pmid:15010800 |
Totsuka K et al. | Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans. | 1992 | Antimicrob. Agents Chemother. | pmid:1503437 |
Nakashima M et al. | Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores. | 1992 | Antimicrob. Agents Chemother. | pmid:1503438 |