MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pivalic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Psoriasis | D011565 | 47 associated lipids |
Seizures | D012640 | 87 associated lipids |
Hemolysis | D006461 | 131 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Takahashi Y et al. | A case of sudden unexpected infant death involving a homozygotic twin with the thermolabile CPT2 variant, accompanied by rotavirus infection and treatment with an antibiotic containing pivalic acid. | 2016 | Leg Med (Tokyo) | pmid:27591533 |
Wu DR et al. | Additive free preparative chiral SFC separations of 2,2-dimethyl-3-aryl-propanoic acids. | 2016 | J Pharm Biomed Anal | pmid:27522108 |
Stanton BA | Characterization of apical and basolateral membrane conductances of rat inner medullary collecting duct. | 1989 | Am. J. Physiol. | pmid:2719119 |
Lin Y et al. | Cooperative catalysis of N-heterocyclic carbene and Brønsted acid for a highly enantioselective route to unprotected spiro-indoline-pyrans. | 2015 | Chem. Commun. (Camb.) | pmid:25882587 |
Melegh B | Carnitine supplementation in pivampicillin treatment. | 1989 | Lancet | pmid:2572813 |
Holme E et al. | Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. | 1989 | Lancet | pmid:2570185 |
Hughes CS et al. | Effects of certain stress factors on the re-excretion of infectious laryngotracheitis virus from latently infected carrier birds. | 1989 | Res. Vet. Sci. | pmid:2539638 |
Nasu T et al. | Newborn hypocarnitinemia due to long-term transplacental pivalic acid passage. | 2014 | Pediatr Int | pmid:25335995 |
Manolikakes SM et al. | Air-stable solid aryl and heteroaryl organozinc pivalates: syntheses and applications in organic synthesis. | 2014 | Chemistry | pmid:25116852 |
Witney TH et al. | Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection. | 2014 | J. Nucl. Med. | pmid:25012458 |
Srinivas HD et al. | Enantiospecific, nickel-catalyzed cross-couplings of allylic pivalates and arylboroxines. | 2014 | Org. Lett. | pmid:24927013 |
Yahyaoui R et al. | [C5-carnitine false positive results in newborn screening: what is the cause?]. | 2015 | Med Clin (Barc) | pmid:24889749 |
Lu Q et al. | Mechanistic study of chemoselectivity in Ni-catalyzed coupling reactions between azoles and aryl carboxylates. | 2014 | J. Am. Chem. Soc. | pmid:24823646 |
Zhou Q et al. | In situ generation of palladium nanoparticles: ligand-free palladium catalyzed pivalic acid assisted carbonylative Suzuki reactions at ambient conditions. | 2014 | J. Org. Chem. | pmid:24397578 |
Boemer F et al. | Surprising causes of C5-carnitine false positive results in newborn screening. | 2014 | Mol. Genet. Metab. | pmid:24291264 |
Muto K et al. | Isolation, structure, and reactivity of an arylnickel(II) pivalate complex in catalytic C-H/C-O biaryl coupling. | 2013 | J. Am. Chem. Soc. | pmid:24152083 |
Zhou Q et al. | Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: stereospecific formation of diarylalkanes and triarylmethanes. | 2013 | J. Am. Chem. Soc. | pmid:23425080 |
Trost BM et al. | Palladium-catalyzed asymmetric allylic alkylation of 3-aryloxindoles with allylidene dipivalate: a useful enol pivalate product. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23335176 |
Demory E et al. | Fast Pd- and Pd/Cu-catalyzed direct C-H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters. | 2012 | J. Org. Chem. | pmid:22946756 |
Aljaar N et al. | Cu-catalyzed reaction of 1,2-dihalobenzenes with 1,3-cyclohexanediones for the synthesis of 3,4-dihydrodibenzo[b,d]furan-1(2H)-ones. | 2012 | J. Org. Chem. | pmid:22917488 |