Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

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Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

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Authors Title Published Journal PubMed Link
Illg T et al. Continuous synthesis of tert-butyl peroxypivalate using a single-channel microreactor equipped with orifices as emulsification units. 2011 ChemSusChem pmid:21302363
Tobisu M et al. Nickel-catalyzed reductive cleavage of aryl-oxygen bonds in alkoxy- and pivaloxyarenes using hydrosilanes as a mild reducing agent. 2011 Chem. Commun. (Camb.) pmid:21264420
Kotzabasaki V et al. Hexametallic manganese clusters with bulky derivatised salicylaldoximes. 2011 Dalton Trans pmid:21249253
Shoman ME et al. Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties. 2011 J. Med. Chem. pmid:21247168
Schmidt J et al. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. 2011 J. Biol. Chem. pmid:21220428
Overgaard J et al. Tetra-kis(μ-pivalato-κO:O')bis-[(2-methyl-pyridine-κN)iron(II)](Fe-Fe). 2008 Acta Crystallogr Sect E Struct Rep Online pmid:21201879
Villa G et al. Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. 2010 Mol Pain pmid:21143950
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Abbas G et al. Series of isostructural planar lanthanide complexes [Ln(III)4(mu3-OH)2(mdeaH)2(piv)8] with single molecule magnet behavior for the Dy4 analogue. 2010 Inorg Chem pmid:20704320
Jarenmark M et al. Unsymmetrical dizinc complexes as models for the active sites of phosphohydrolases. 2010 Dalton Trans pmid:20683537
Rousseaux S et al. Investigation of the mechanism of C(sp3)-H bond cleavage in Pd(0)-catalyzed intramolecular alkane arylation adjacent to amides and sulfonamides. 2010 J. Am. Chem. Soc. pmid:20681702
Sobkowski M et al. Stereochemistry of internucleotide bond formation by the H-phosphonate method. 5. The role of Brønsted and H-bonding base catalysis in ribonucleoside H-phosphonate condensation-chemical and stereochemical consequences. 2010 Nucleosides Nucleotides Nucleic Acids pmid:20661816
Nakajima Y et al. Detection of pivaloylcarnitine in pediatric patients with hypocarnitinemia after long-term administration of pivalate-containing antibiotics. 2010 Tohoku J. Exp. Med. pmid:20651467
Govindan S et al. Ca(2+) signalling by P2Y receptors in cultured rat aortic smooth muscle cells. 2010 Br. J. Pharmacol. pmid:20649593
Will KW et al. Quantification and evidence for mechanically metered release of pygidial secretions in formic acid-producing carabid beetles. 2010 J. Insect Sci. pmid:20575743
Rumschinski P et al. Set-base dynamical parameter estimation and model invalidation for biochemical reaction networks. 2010 BMC Syst Biol pmid:20500862
Lyubinetsky I et al. Adsorption states and mobility of trimethylacetic acid molecules on reduced TiO(2)(110) surface. 2010 Phys Chem Chem Phys pmid:20490397
Zhao XQ et al. Synthesis, structures and magnetic properties of a series of 3d-4f tetranuclear Co(II)â‚‚Ln(III)â‚‚ cubanes. 2010 Dalton Trans pmid:20401413
Liu TF et al. An alcoholysis route to a Cu16 cluster, and the influence of the alcohol. 2010 Dalton Trans pmid:20354607
Cox AD et al. Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: chemical strategies to prepare glycoconjugates with good carbohydrate loading. 2010 Glycoconj. J. pmid:20340043