| MeSH term | MeSH ID | Detail |
|---|---|---|
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Vitamin B Deficiency | D014804 | 4 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Dihydropyrimidine Dehydrogenase Deficiency | D054067 | 1 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhao D et al. | Phosphine-free, palladium-catalyzed arylation of heterocycles through C-H bond activation with pivalic acid as a cocatalyst. | 2009 | Chemistry | pmid:19115287 |
| Langley SK et al. | Structure, magnetism and theory of a family of nonanuclear Cu(II)5Ln(III)4-triethanolamine clusters displaying single-molecule magnet behaviour. | 2011 | Chemistry | pmid:21732432 |
| Overgaard J et al. | Host-guest chemistry of the chromium-wheel complex [Cr8F8(tBuCO2)16]: prediction of inclusion capabilities by using an electrostatic potential distribution determined by modeling synchrotron X-ray structure factors at 16 K. | 2002 | Chemistry | pmid:12391657 |
| Grillo MP and Hua F | Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes. | 2008 | Chem. Res. Toxicol. | pmid:18680316 |
| Li C et al. | Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes. | 2002 | Chem. Res. Toxicol. | pmid:12437340 |
| Tobisu M et al. | Nickel-catalyzed reductive cleavage of aryl-oxygen bonds in alkoxy- and pivaloxyarenes using hydrosilanes as a mild reducing agent. | 2011 | Chem. Commun. (Camb.) | pmid:21264420 |
| Langley SK et al. | A high nuclearity mixed valence {Mn32} complex. | 2011 | Chem. Commun. (Camb.) | pmid:21503362 |
| Rajaraman G et al. | Theoretical studies on di- and tetra-nuclear Ni pivalate complexes. | 2005 | Chem. Commun. (Camb.) | pmid:15959582 |
| Goossen LJ and RodrÃguez N | A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction. | 2004 | Chem. Commun. (Camb.) | pmid:15010800 |
| Lin Y et al. | Cooperative catalysis of N-heterocyclic carbene and Brønsted acid for a highly enantioselective route to unprotected spiro-indoline-pyrans. | 2015 | Chem. Commun. (Camb.) | pmid:25882587 |
| Todesco L et al. | Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2. | 2009 | Chem. Biol. Interact. | pmid:19539806 |
| Ercolani L and Schulte WE | Metabolic and morphologic effects of colchicine on human T-lymphocyte expression of Fc mu and Fc gamma receptors. | 1983 | Cell. Immunol. | pmid:6303602 |
| Kuka J et al. | A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function. | 2012 | Cardiovasc. Toxicol. | pmid:22539084 |
| Broderick TL et al. | L-carnitine improvement of cardiac function is associated with a stimulation in glucose but not fatty acid metabolism in carnitine-deficient hearts. | 1995 | Cardiovasc. Res. | pmid:8595631 |
| Barroca N and Jacquinet JC | An access to various sulfation patterns in dermatan sulfate: chemical syntheses of sulfoforms of trisaccharide methyl glycosides. | 2002 | Carbohydr. Res. | pmid:11950464 |
| Tomić S et al. | Partial purification of esterases from rabbit serum and their use in regioselective deacylations of sugars. | 1991 | Carbohydr. Res. | pmid:1878876 |
| Kornilov AV et al. | Preparative route to glucuronyl donors bearing temporary protecting group at O-3 via 6,3-lactonisation by Bz(2)O or Piv(2)O. | 2001 | Carbohydr. Res. | pmid:11728399 |
| Cutts SM et al. | Molecular basis for the synergistic interaction of adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9). | 2001 | Cancer Res. | pmid:11719450 |
| Mattocks AR and Cabral JR | Carcinogenicity of some pyrrolic pyrrolizidine alkaloid metabolites and analogues. | 1982 | Cancer Lett. | pmid:6817913 |
| Broderick TL et al. | Short-term carnitine deficiency does not alter aerobic rat heart function but depresses reperfusion recovery after ischemia. | 2001 | Can. J. Physiol. Pharmacol. | pmid:11697749 |