| MeSH term | MeSH ID | Detail |
|---|---|---|
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Vitamin B Deficiency | D014804 | 4 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Dihydropyrimidine Dehydrogenase Deficiency | D054067 | 1 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Abrahamsson K et al. | Impaired ketogenesis in carnitine depletion caused by short-term administration of pivalic acid prodrug. | 1994 | Biochem. Med. Metab. Biol. | pmid:7917463 |
| Diep QN et al. | Formation of pivaloylcarnitine in heart and brown adipose tissue in the rat. | 1995 | Biochim. Biophys. Acta | pmid:7827109 |
| Diep QN and Bøhmer T | Increased pivaloylcarnitine in the liver of the sodium pivalate treated rat exposed to clofibrate. | 1995 | Biochim. Biophys. Acta | pmid:7766704 |
| Broderick TL et al. | Fatty acid oxidation and cardiac function in the sodium pivalate model of secondary carnitine deficiency. | 1995 | Metab. Clin. Exp. | pmid:7723673 |
| Broderick TL et al. | L-propionylcarnitine effects on cardiac carnitine content and function in secondary carnitine deficiency. | 1995 | Can. J. Physiol. Pharmacol. | pmid:7671193 |
| Abrahamsson K et al. | Effect of short-term treatment with pivalic acid containing antibiotics on serum carnitine concentration--a risk irrespective of age. | 1995 | Biochem. Mol. Med. | pmid:7551831 |
| Mizojiri K et al. | Disposition of S-1108, a new oral cephem antibiotic, and metabolic fate of pivalic acid liberated from [pivaloyl-14C]S-1108 in rats and dogs. | 1995 | Antimicrob. Agents Chemother. | pmid:7492083 |
| Diep QN et al. | Formation of pivaloylcarnitine in isolated rat heart cells. | 1995 | Biochim. Biophys. Acta | pmid:7488636 |
| Morris GS et al. | Sodium pivalate reduces cardiac carnitine content and increases glucose oxidation without affecting cardiac functional capacity. | 1995 | Life Sci. | pmid:7475977 |
| Staatz WD et al. | Cytotoxicity of pivalylphenylephrine and pivalic acid to corneal endothelium. | 1980 | Arch. Ophthalmol. | pmid:7396784 |
| Lloyd S et al. | The effect of corticosteroid therapy on infection with Toxocara canis in dogs. | 1981 | Z Parasitenkd | pmid:7324542 |
| Nakamura T et al. | Effect of d,l-alpha-tocopheryl esters on vitamin E-deficient rats. | 1978 | J. Nutr. Sci. Vitaminol. | pmid:731332 |
| Fairclough RJ et al. | Dexamethasone concentrations in plasma and milk of cows following the injection of long- and short-acting dexamethasone esters. | 1981 | Aust. J. Biol. Sci. | pmid:7295211 |
| Deutsch C et al. | Synaptosomes from rat brain: morphology, compartmentation, and transmembrane pH and electrical gradients. | 1981 | J. Neurochem. | pmid:7241148 |
| Goldberg I et al. | Dipivefrin: current concepts. | 1980 | Aust J Ophthalmol | pmid:7004425 |
| Mattocks AR and Cabral JR | Carcinogenicity of some pyrrolic pyrrolizidine alkaloid metabolites and analogues. | 1982 | Cancer Lett. | pmid:6817913 |
| Peel CJ et al. | The importance of prolactin and the milking stimulus in the artificial induction of lactation in cows. | 1978 | Aust. J. Biol. Sci. | pmid:678223 |
| Van Dort M et al. | Potential tumor or organ-imaging agents, 24. Radioiodinated pregnenolone esters. | 1984 | Steroids | pmid:6537047 |
| Tamaru RD et al. | Comparison of ocular disposition of free pivalic acid and pivalic acid esterified in dipivefrin. | 1983 | Arch. Ophthalmol. | pmid:6347153 |
| Ercolani L and Schulte WE | Metabolic and morphologic effects of colchicine on human T-lymphocyte expression of Fc mu and Fc gamma receptors. | 1983 | Cell. Immunol. | pmid:6303602 |