MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Dermatitis | D003872 | 30 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pivalic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Dermatitis | D003872 | 30 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Bailey LF et al. | The use of dexamethasone trimethylacetate to advance parturition in dairy cows. | 1973 | Aust. Vet. J. | pmid:4777214 |
Fulkerson WJ and McDowell GH | Artificial induction of lactation in cattle by use of dexamethasone trimethylacetate. | 1975 | Aust. J. Biol. Sci. | pmid:1167131 |
Czerkawski JW and Breckenridge G | New inhibitors of methane production by rumen micro-organisms. Development and testing of inhibitors in vitro. | 1975 | Br. J. Nutr. | pmid:1201267 |
Fulkerson WJ et al. | Artificial induction of lactation in ewes: the role of prolactin. | 1975 | Aust. J. Biol. Sci. | pmid:1243818 |
Czerkawski JW | The use of pivalic acid as a reference substance in measurements of production of volatile fatty acids by rumen micro-organisms in vitro. | 1976 | Br. J. Nutr. | pmid:952843 |
Douglas KT et al. | Mechanistic studies of carboxypeptidase Y. Kinetic detection of an acyl-enzyme intermediate in trimethylacetate esterase action. | 1976 | J. Am. Chem. Soc. | pmid:993522 |
Sloan CA | Proceedings: Comparison of dexamethasone trimethylacetate and prostaglandin F-2alpha as abortifacients in the cow. | 1976 | J. Reprod. Fertil. | pmid:1255625 |
Reckers VR and Wendt H | [Multicentre-clinical trial of the novel corticosteroid diflucortolone valerate in the forms of cream, ointment and fatty ointment. Part I: Comparative study of diflucortolone valerate with fluocortolone, -capronate, -pivalate in a double-blind contralateral design with topical application (author's transl)]. | 1976 | Arzneimittelforschung | pmid:795433 |
Gaskell RM and Povey RC | Experimental induction of feline viral rhinotracheitis virus re-excretion in FVR-recovered cats. | 1977 | Vet. Rec. | pmid:191978 |
Wexler BC | Corticotropin stimulation of hypertensive rats with and without arteriosclerosis. | 1978 | Arch. Pathol. Lab. Med. | pmid:214053 |
Mazauric FX and Alligier B | [Trial of tixocortol pivalate (Pivalone) in otorhinolaryngology]. | 1978 | J Fr Otorhinolaryngol Audiophonol Chir Maxillofac | pmid:154555 |
Peel CJ et al. | The importance of prolactin and the milking stimulus in the artificial induction of lactation in cows. | 1978 | Aust. J. Biol. Sci. | pmid:678223 |
Nakamura T et al. | Effect of d,l-alpha-tocopheryl esters on vitamin E-deficient rats. | 1978 | J. Nutr. Sci. Vitaminol. | pmid:731332 |
MacDiarmid SC | Betamethasone alcohol suspensions for the induction of parturition in dairy cows: a comparison with dexamethasone trimethyl acetate. | 1979 | N Z Vet J | pmid:292913 |
Crofton JT et al. | The importance of vasopressin in the development and maintenance of DOC-salt hypertension in the rat. | 1979 Jan-Feb | Hypertension | pmid:544512 |
Staatz WD et al. | Cytotoxicity of pivalylphenylephrine and pivalic acid to corneal endothelium. | 1980 | Arch. Ophthalmol. | pmid:7396784 |
Goldberg I et al. | Dipivefrin: current concepts. | 1980 | Aust J Ophthalmol | pmid:7004425 |
Deutsch C et al. | Synaptosomes from rat brain: morphology, compartmentation, and transmembrane pH and electrical gradients. | 1981 | J. Neurochem. | pmid:7241148 |
Fairclough RJ et al. | Dexamethasone concentrations in plasma and milk of cows following the injection of long- and short-acting dexamethasone esters. | 1981 | Aust. J. Biol. Sci. | pmid:7295211 |
Lloyd S et al. | The effect of corticosteroid therapy on infection with Toxocara canis in dogs. | 1981 | Z Parasitenkd | pmid:7324542 |
Mattocks AR and Cabral JR | Carcinogenicity of some pyrrolic pyrrolizidine alkaloid metabolites and analogues. | 1982 | Cancer Lett. | pmid:6817913 |
Andersson L et al. | Glucose concentrations in plasma and urine after glucocorticoid injection in healthy cows. | 1982 Apr-May | Nord Vet Med | pmid:6184673 |
Ercolani L and Schulte WE | Metabolic and morphologic effects of colchicine on human T-lymphocyte expression of Fc mu and Fc gamma receptors. | 1983 | Cell. Immunol. | pmid:6303602 |
Tamaru RD et al. | Comparison of ocular disposition of free pivalic acid and pivalic acid esterified in dipivefrin. | 1983 | Arch. Ophthalmol. | pmid:6347153 |
Van Dort M et al. | Potential tumor or organ-imaging agents, 24. Radioiodinated pregnenolone esters. | 1984 | Steroids | pmid:6537047 |
Vickers S et al. | Metabolism of methyldopa in man after oral administration of the pivaloyloxyethyl ester. | 1984 Mar-Apr | Drug Metab. Dispos. | pmid:6144491 |
Vickers S et al. | Carnitine and glucuronic acid conjugates of pivalic acid. | 1985 | Xenobiotica | pmid:4036169 |
Dzielak DJ and Norman RA | Renal nerves are not necessary for onset or maintenance of DOC-salt hypertension in rats. | 1985 | Am. J. Physiol. | pmid:4061671 |
Romani G et al. | H extrusion and potassium uptake associated with potential hyperpolarization in maize and wheat root segments treated with permeant weak acids. | 1985 | Plant Physiol. | pmid:16664483 |
Johnston NE and Stewart JA | The effect of glucocorticoids and prematurity on absorption of colostral immunoglobulin in the calf. | 1986 | Aust. Vet. J. | pmid:3767799 |
Foussereau J and Jelen G | [An unrecognized cause of allergic eczema of the face: a corticoid, tixocortol pivalate]. | 1987 | Presse Med | pmid:2954110 |
Chattopadhyay SP et al. | Betamethasone dipropionate (0.05%) plus salicylic acid (3%) ointment versus dexamethasone trimethyl acetate (1%) and salicylic acid 4% ointments in chronic dermatoses. | 1987 | Indian J Dermatol | pmid:3453353 |
Melegh B et al. | Pivampicillin-promoted excretion of pivaloylcarnitine in humans. | 1987 | Biochem. Pharmacol. | pmid:3675603 |
Sciotti V and Gallant S | Resistance to mineralocorticoid-induced hypertensive vascular disease. | 1987 | Hypertension | pmid:3610293 |
Hussain MA et al. | Improvement of the oral bioavailability of naltrexone in dogs: a prodrug approach. | 1987 | J Pharm Sci | pmid:3656096 |
Lelièvre V et al. | Correlation between binding activity, inhibition of lymphoblastic transformation and metabolism of tixocortol 21 pivalate in mouse thymocytes. | 1987 | Agents Actions | pmid:3500591 |
Basso B and Ullrich-Eberius CI | Membrane Potential and Proton Cotransport of Alanine and Phosphate as Affected by Permeant Weak Acids in Lemna gibba. | 1987 | Plant Physiol. | pmid:16665758 |
Bruner CA et al. | Area postrema ablation and vascular reactivity in deoxycorticosterone-salt-treated rats. | 1988 | Hypertension | pmid:3391678 |
Ueno Y et al. | Characteristics of hormonal and neurogenic mechanisms of deoxycorticosterone-induced hypertension. | 1988 | Hypertension | pmid:3346052 |
Maurer H and Kessler C | Identification and quantification of ethylene glycol and diethylene glycol in plasma using gas chromatography-mass spectrometry. | 1988 | Arch. Toxicol. | pmid:3190459 |
Holme E et al. | Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. | 1989 | Lancet | pmid:2570185 |
Melegh B | Carnitine supplementation in pivampicillin treatment. | 1989 | Lancet | pmid:2572813 |
Hughes CS et al. | Effects of certain stress factors on the re-excretion of infectious laryngotracheitis virus from latently infected carrier birds. | 1989 | Res. Vet. Sci. | pmid:2539638 |
Stanton BA | Characterization of apical and basolateral membrane conductances of rat inner medullary collecting duct. | 1989 | Am. J. Physiol. | pmid:2719119 |
Haradahira T et al. | Potential tumor- or organ-imaging agents. 29. Radioiodinated esters and amides of 20-hydroxy- and 20-aminopregn-5-en-3 beta-ols. | 1989 | J. Med. Chem. | pmid:2918507 |
Freed JJ et al. | Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells. | 1989 | Biochem. Pharmacol. | pmid:2818620 |
Tomić S et al. | Partial purification of esterases from rabbit serum and their use in regioselective deacylations of sugars. | 1991 | Carbohydr. Res. | pmid:1878876 |
Ruff LJ and Brass EP | Metabolic effects of pivalate in isolated rat hepatocytes. | 1991 | Toxicol. Appl. Pharmacol. | pmid:1891775 |
Bianchi PB and Davis AT | Sodium pivalate treatment reduces tissue carnitines and enhances ketosis in rats. | 1991 | J. Nutr. | pmid:1941267 |