MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Dermatitis | D003872 | 30 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Pivalic acid
MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Dermatitis | D003872 | 30 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Basso B and Ullrich-Eberius CI | Membrane Potential and Proton Cotransport of Alanine and Phosphate as Affected by Permeant Weak Acids in Lemna gibba. | 1987 | Plant Physiol. | pmid:16665758 |
Färber K et al. | Selective desensitization of jasmonate- and pH-dependent signaling in the induction of benzophenanthridine biosynthesis in cells of Eschscholzia californica. | 2003 | Phytochemistry | pmid:12620362 |
Lyubinetsky I et al. | Adsorption states and mobility of trimethylacetic acid molecules on reduced TiO(2)(110) surface. | 2010 | Phys Chem Chem Phys | pmid:20490397 |
Chisholm MH | Mixed valence complexes involving MM quadruple bonds (M=Mo or W). | 2008 | Philos Trans A Math Phys Eng Sci | pmid:17846014 |
Brass EP | Pivalate-generating prodrugs and carnitine homeostasis in man. | 2002 | Pharmacol. Rev. | pmid:12429869 |
Rispoli V et al. | Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats. | 2004 | Pharmacol. Biochem. Behav. | pmid:15301920 |
Okudaira N et al. | Up-regulation of carnitine transporters helps maintain tissue carnitine levels in carnitine deficiency induced by pivalic acid. | 2001 | Pharm. Res. | pmid:11451029 |
Yuan LC et al. | Effect of carbonate salts on the kinetics of acid-catalyzed dimerization of adefovir dipivoxil. | 2000 | Pharm. Res. | pmid:11087042 |
Okamura N et al. | Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid. | 2006 | Pharm. Res. | pmid:16826461 |
Makino Y et al. | Carnitine-associated encephalopathy caused by long-term treatment with an antibiotic containing pivalic acid. | 2007 | Pediatrics | pmid:17724113 |