Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Purine-Pyrimidine Metabolism, Inborn Errors D011686 5 associated lipids
Vitamin B Deficiency D014804 4 associated lipids
Toxocariasis D014120 3 associated lipids
Dihydropyrimidine Dehydrogenase Deficiency D054067 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Nasu T et al. Newborn hypocarnitinemia due to long-term transplacental pivalic acid passage. 2014 Pediatr Int pmid:25335995
Manolikakes SM et al. Air-stable solid aryl and heteroaryl organozinc pivalates: syntheses and applications in organic synthesis. 2014 Chemistry pmid:25116852
Rasmussen J et al. Primary carnitine deficiency and pivalic acid exposure causing encephalopathy and fatal cardiac events. 2013 J. Inherit. Metab. Dis. pmid:22566287
Trost BM et al. Palladium-catalyzed asymmetric allylic alkylation of 3-aryloxindoles with allylidene dipivalate: a useful enol pivalate product. 2013 Angew. Chem. Int. Ed. Engl. pmid:23335176
Muto K et al. Isolation, structure, and reactivity of an arylnickel(II) pivalate complex in catalytic C-H/C-O biaryl coupling. 2013 J. Am. Chem. Soc. pmid:24152083
Zhou Q et al. Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: stereospecific formation of diarylalkanes and triarylmethanes. 2013 J. Am. Chem. Soc. pmid:23425080
Demory E et al. Fast Pd- and Pd/Cu-catalyzed direct C-H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters. 2012 J. Org. Chem. pmid:22946756
Shan Y et al. Rapid acyl migration between pyrogallyl 1,2- and 1,3-dipivaloates. 2012 Nat Prod Commun pmid:22545406
Rezanka T et al. Biosynthesis and metabolic pathways of pivalic acid. 2012 Appl. Microbiol. Biotechnol. pmid:22790609
Kuka J et al. A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function. 2012 Cardiovasc. Toxicol. pmid:22539084