| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dihydropyrimidine Dehydrogenase Deficiency | D054067 | 1 associated lipids |
| Toxocariasis | D014120 | 3 associated lipids |
| Vitamin B Deficiency | D014804 | 4 associated lipids |
| Purine-Pyrimidine Metabolism, Inborn Errors | D011686 | 5 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang JK et al. | Effect of MK-886 on Ca2+ level and viability in PC3 human prostate cancer cells. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19371256 |
| Abrahamsson K et al. | Impaired ketogenesis in carnitine depletion caused by short-term administration of pivalic acid prodrug. | 1994 | Biochem. Med. Metab. Biol. | pmid:7917463 |
| Abrahamsson K et al. | Effect of short-term treatment with pivalic acid containing antibiotics on serum carnitine concentration--a risk irrespective of age. | 1995 | Biochem. Mol. Med. | pmid:7551831 |
| Freed JJ et al. | Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells. | 1989 | Biochem. Pharmacol. | pmid:2818620 |
| Melegh B et al. | Pivampicillin-promoted excretion of pivaloylcarnitine in humans. | 1987 | Biochem. Pharmacol. | pmid:3675603 |
| Diep QN et al. | Formation of pivaloylcarnitine in isolated rat heart cells. | 1995 | Biochim. Biophys. Acta | pmid:7488636 |
| Diep QN et al. | Formation of pivaloylcarnitine in heart and brown adipose tissue in the rat. | 1995 | Biochim. Biophys. Acta | pmid:7827109 |
| Diep QN and Bøhmer T | Increased pivaloylcarnitine in the liver of the sodium pivalate treated rat exposed to clofibrate. | 1995 | Biochim. Biophys. Acta | pmid:7766704 |
| Kvach MV et al. | 5(6)-carboxyfluorescein revisited: new protecting group, separation of isomers, and their spectral properties on oligonucleotides. | 2007 Sep-Oct | Bioconjug. Chem. | pmid:17696491 |
| Davis AT | Carnitine depletion in rat pups of lactating mothers given sodium pivalate. | 1995 | Biol. Neonate | pmid:8534786 |