Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Dihydropyrimidine Dehydrogenase Deficiency D054067 1 associated lipids
Toxocariasis D014120 3 associated lipids
Vitamin B Deficiency D014804 4 associated lipids
Purine-Pyrimidine Metabolism, Inborn Errors D011686 5 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Otitis Media D010033 12 associated lipids
Hyperinsulinism D006946 27 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Dermatitis D003872 30 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

Download all related citations
Per page 10 20 50 100 | Total 272
Authors Title Published Journal PubMed Link
Kalavala M et al. Tixocortol pivalate: what is the right concentration? 2007 Contact Derm. pmid:17577357
Doberenz J et al. Pivalate lowers litter sizes and weights in female rats independent of its effect on carnitine status. 2007 Reprod. Toxicol. pmid:17482425
Makino Y et al. Carnitine-associated encephalopathy caused by long-term treatment with an antibiotic containing pivalic acid. 2007 Pediatrics pmid:17724113
Cornwell PD and Ulrich RG Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles. 2007 Toxicol Pathol pmid:17654398
Kaitner B and Stilinović V Conformational enantiomeric disorder in tripivaloylmethane. 2007 Acta Crystallogr C pmid:17551202
Murakami K et al. Chromium-catalyzed arylmagnesiation of alkynes. 2007 Org. Lett. pmid:17352489
Milios CJ et al. 1,1,1-Tris(hydroxymethyl)propane in manganese carboxylate chemistry: synthesis, structure and magnetic properties of a mixed-valence [MnIII4MnII4] cluster featuring the novel [MnIII4MnII4(mu3-OR)6(mu2-OR)8]6+ core. 2006 Dalton Trans pmid:16365649
Lee J et al. 2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands. 2006 Bioorg. Med. Chem. pmid:16297629
Chakraborti AK and Shivani S Magnesium bistrifluoromethanesulfonimide as a new and efficient acylation catalyst. 2006 J. Org. Chem. pmid:16839166
Yamaguchi T et al. Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats. 2006 Toxicol. Appl. Pharmacol. pmid:16430936
Sibi MP and Zimmerman J Pyrones to pyrans: enantioselective radical additions to acyloxy pyrones. 2006 J. Am. Chem. Soc. pmid:17031933
Suga K et al. Photocatalytic oxygenation of pivalic acid with molecular oxygen via photoinduced electron transfer using 10-methylacridinium ions. 2006 J Phys Chem A pmid:16539406
Broderick TL Hypocarnitinaemia induced by sodium pivalate in the rat is associated with left ventricular dysfunction and impaired energy metabolism. 2006 Drugs R D pmid:16752941
Okamura N et al. Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid. 2006 Pharm. Res. pmid:16826461
Lafrance M and Fagnou K Palladium-catalyzed benzene arylation: incorporation of catalytic pivalic acid as a proton shuttle and a key element in catalyst design. 2006 J. Am. Chem. Soc. pmid:17177387
Shanmugam M et al. Studies of a molecular hourglass: synthesis and magnetic characterisation of a cyclic dodecanuclear {Cr10Cu2} complex. 2006 Chemistry pmid:17009364
Sugiura T et al. 1D helical polymeric chain with a pseudo-5(3) screw axis formed by cuprophilicity. synthesis and crystal structure of copper(I) pivalate. 2006 Inorg Chem pmid:16961347
Mansell PD et al. Induction of parturition in dairy cattle and its effects on health and subsequent lactation and reproductive performance. 2006 Aust. Vet. J. pmid:16958626
Wittick LM et al. New mixed-valence MnII2MnIII2 clusters exhibiting an unprecedented MnII/III oxidation state distribution in their magnetically coupled cores. 2006 Dalton Trans pmid:16538272
Sasahara A et al. STM observation of a ruthenium dye adsorbed on a TiO2(110) surface. 2006 J Phys Chem B pmid:16526711