| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dihydropyrimidine Dehydrogenase Deficiency | D054067 | 1 associated lipids |
| Toxocariasis | D014120 | 3 associated lipids |
| Vitamin B Deficiency | D014804 | 4 associated lipids |
| Purine-Pyrimidine Metabolism, Inborn Errors | D011686 | 5 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ito T | Children's toxicology from bench to bed--Liver injury (1): Drug-induced metabolic disturbance--toxicity of 5-FU for pyrimidine metabolic disorders and pivalic acid for carnitine metabolism. | 2009 | J Toxicol Sci | pmid:19571472 |
| Goikhman R et al. | C-H bonds as ubiquitous functionality: a general approach to complex arylated pyrazoles via sequential regioselective C-arylation and N-alkylation enabled by SEM-group transposition. | 2009 | J. Am. Chem. Soc. | pmid:19206533 |
| Douglas KT et al. | Mechanistic studies of carboxypeptidase Y. Kinetic detection of an acyl-enzyme intermediate in trimethylacetate esterase action. | 1976 | J. Am. Chem. Soc. | pmid:993522 |
| Ferrer Flegeau E et al. | Autocatalysis for C-H bond activation by ruthenium(II) complexes in catalytic arylation of functional arenes. | 2011 | J. Am. Chem. Soc. | pmid:21604765 |
| Spino C et al. | A stereodivergent approach to chiral nonracemic N-protected alpha,alpha-dialkylated amino acids. | 2003 | J. Am. Chem. Soc. | pmid:14518992 |
| Rousseaux S et al. | Investigation of the mechanism of C(sp3)-H bond cleavage in Pd(0)-catalyzed intramolecular alkane arylation adjacent to amides and sulfonamides. | 2010 | J. Am. Chem. Soc. | pmid:20681702 |
| Li G et al. | Au-catalyzed synthesis of (1Z,3E)-2-pivaloxy-1,3-dienes from propargylic pivalates. | 2008 | J. Am. Chem. Soc. | pmid:18311985 |
| Sibi MP and Zimmerman J | Pyrones to pyrans: enantioselective radical additions to acyloxy pyrones. | 2006 | J. Am. Chem. Soc. | pmid:17031933 |
| Quasdorf KW et al. | Cross-coupling reactions of aryl pivalates with boronic acids. | 2008 | J. Am. Chem. Soc. | pmid:18839946 |
| Lafrance M and Fagnou K | Palladium-catalyzed benzene arylation: incorporation of catalytic pivalic acid as a proton shuttle and a key element in catalyst design. | 2006 | J. Am. Chem. Soc. | pmid:17177387 |
| Arulsamy N and Bohle DS | Multiplicity control in the polygeminal diazeniumdiolation of active hydrogen bearing carbons: chemistry of a new type of trianionic molecular propeller. | 2001 | J. Am. Chem. Soc. | pmid:11686687 |
| Milios CJ et al. | Toward a magnetostructural correlation for a family of Mn6 SMMs. | 2007 | J. Am. Chem. Soc. | pmid:17887755 |
| Muto K et al. | Isolation, structure, and reactivity of an arylnickel(II) pivalate complex in catalytic C-H/C-O biaryl coupling. | 2013 | J. Am. Chem. Soc. | pmid:24152083 |
| Zhou Q et al. | Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: stereospecific formation of diarylalkanes and triarylmethanes. | 2013 | J. Am. Chem. Soc. | pmid:23425080 |
| Wang X et al. | Direct C-arylation of free (NH)-indoles and pyrroles catalyzed by Ar-Rh(III) complexes assembled in situ. | 2005 | J. Am. Chem. Soc. | pmid:15810815 |
| Qian H et al. | Platinum-catalyzed intramolecular hydroalkoxylation of gamma- and delta-hydroxy olefins to form cyclic ethers. | 2004 | J. Am. Chem. Soc. | pmid:15291546 |
| Bursten BE et al. | Oxalate-bridged complexes of dimolybdenum and ditungsten supported by pivalate ligands: ((t)BuCO(2))(3)M(2)(mu-O(2)CCO(2))M(2)(O(2)C(t)Bu)(3). Correlation of the solid-state, molecular, and electronic structures with Raman, resonance Raman, and electronic spectral data. | 2002 | J. Am. Chem. Soc. | pmid:11902897 |
| Lu Q et al. | Mechanistic study of chemoselectivity in Ni-catalyzed coupling reactions between azoles and aryl carboxylates. | 2014 | J. Am. Chem. Soc. | pmid:24823646 |
| Solano-Serena F et al. | Degradation of isooctane by Mycobacterium austroafricanum IFP 2173: growth and catabolic pathway. | 2004 | J. Appl. Microbiol. | pmid:15281945 |
| Blanton MP et al. | Examining the noncompetitive antagonist-binding site in the ion channel of the nicotinic acetylcholine receptor in the resting state. | 2000 | J. Biol. Chem. | pmid:10652341 |