| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Purine-Pyrimidine Metabolism, Inborn Errors | D011686 | 5 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Toxocariasis | D014120 | 3 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Singh S and Mann BK | Clinical utility of clocortolone pivalate for the treatment of corticosteroid-responsive skin disorders: a systematic review. | 2012 | Clin Cosmet Investig Dermatol | pmid:22791998 |
| Kalavala M et al. | Tixocortol pivalate: what is the right concentration? | 2007 | Contact Derm. | pmid:17577357 |
| Leone G et al. | Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias. | 2008 | Curr. Med. Chem. | pmid:18537607 |
| Shishilov ON et al. | Palladium(II) carboxylates and palladium(I) carbonyl carboxylate complexes as catalysts for olefin cyclopropanation with ethyl diazoacetate. | 2009 | Dalton Trans | pmid:19672507 |
| Kotzabasaki V et al. | Hexametallic manganese clusters with bulky derivatised salicylaldoximes. | 2011 | Dalton Trans | pmid:21249253 |
| Zhao XQ et al. | Synthesis, structures and magnetic properties of a series of 3d-4f tetranuclear Co(II)â‚‚Ln(III)â‚‚ cubanes. | 2010 | Dalton Trans | pmid:20401413 |
| Milios CJ et al. | 1,1,1-Tris(hydroxymethyl)propane in manganese carboxylate chemistry: synthesis, structure and magnetic properties of a mixed-valence [MnIII4MnII4] cluster featuring the novel [MnIII4MnII4(mu3-OR)6(mu2-OR)8]6+ core. | 2006 | Dalton Trans | pmid:16365649 |
| Liu TF et al. | An alcoholysis route to a Cu16 cluster, and the influence of the alcohol. | 2010 | Dalton Trans | pmid:20354607 |
| Wittick LM et al. | New mixed-valence MnII2MnIII2 clusters exhibiting an unprecedented MnII/III oxidation state distribution in their magnetically coupled cores. | 2006 | Dalton Trans | pmid:16538272 |
| Chaboussant G et al. | Nickel pivalate complexes: structural variations and magnetic susceptibility and inelastic neutron scattering studies. | 2004 | Dalton Trans | pmid:15514763 |
| Christian P et al. | Synthesis and studies of a trinuclear Mn(II) carboxylate complex. | 2004 | Dalton Trans | pmid:15303171 |
| Christian P et al. | Structural, magnetic and DFT studies of a hydroxide-bridged [Cr8] wheel. | 2004 | Dalton Trans | pmid:15252595 |
| Jarenmark M et al. | Unsymmetrical dizinc complexes as models for the active sites of phosphohydrolases. | 2010 | Dalton Trans | pmid:20683537 |
| Vickers S et al. | Metabolism of methyldopa in man after oral administration of the pivaloyloxyethyl ester. | 1984 Mar-Apr | Drug Metab. Dispos. | pmid:6144491 |
| Ohnishi S et al. | Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment. | 2008 | Drug Metab. Pharmacokinet. | pmid:18762717 |
| Arrigoni-Martelli E and Caso V | Carnitine protects mitochondria and removes toxic acyls from xenobiotics. | 2001 | Drugs Exp Clin Res | pmid:11276827 |
| Broderick TL | Hypocarnitinaemia induced by sodium pivalate in the rat is associated with left ventricular dysfunction and impaired energy metabolism. | 2006 | Drugs R D | pmid:16752941 |
| Rezanka T et al. | Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces. | 2011 | Environ. Microbiol. | pmid:21450004 |
| Sauber K et al. | A new esterase for the cleavage of pivalic acid-containing prodrug esters of cephalosporins. | 1996 | Enzyme Microb. Technol. | pmid:8672280 |
| Weis R et al. | Antiplasmodial and antitrypanosomal activity of new esters and ethers of 4-dialkylaminobicyclo[2.2.2]octan-2-ols. | 2006 | Eur J Pharm Sci | pmid:16713699 |