| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Purine-Pyrimidine Metabolism, Inborn Errors | D011686 | 5 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Toxocariasis | D014120 | 3 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Berkovitch G et al. | Novel multifunctional acyloxyalkyl ester prodrugs of 5-aminolevulinic acid display improved anticancer activity independent and dependent on photoactivation. | 2008 | J. Med. Chem. | pmid:19007111 |
| Grillo MP and Hua F | Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes. | 2008 | Chem. Res. Toxicol. | pmid:18680316 |
| Overgaard J et al. | Tetra-kis(μ-pivalato-κO:O')bis-[(2-methyl-pyridine-κN)iron(II)](Fe-Fe). | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21201879 |
| Chisholm MH | Mixed valence complexes involving MM quadruple bonds (M=Mo or W). | 2008 | Philos Trans A Math Phys Eng Sci | pmid:17846014 |
| Hong AW et al. | An expedient route to Montanine-type Amaryllidaceae alkaloids: total syntheses of (-)-brunsvigine and (-)-manthine. | 2008 | J. Org. Chem. | pmid:18781802 |
| Li BJ et al. | Cross-coupling of aryl/alkenyl pivalates with organozinc reagents through nickel-catalyzed C-O bond activation under mild reaction conditions. | 2008 | Angew. Chem. Int. Ed. Engl. | pmid:19016280 |
| Greaves TL et al. | Protic ionic liquids: physicochemical properties and behavior as amphiphile self-assembly solvents. | 2008 | J Phys Chem B | pmid:18166036 |
| Li G et al. | Au-catalyzed synthesis of (1Z,3E)-2-pivaloxy-1,3-dienes from propargylic pivalates. | 2008 | J. Am. Chem. Soc. | pmid:18311985 |
| Quasdorf KW et al. | Cross-coupling reactions of aryl pivalates with boronic acids. | 2008 | J. Am. Chem. Soc. | pmid:18839946 |
| Ikeda M et al. | Scanning tunneling microscopy study of black dye and deoxycholic acid adsorbed on a rutile TiO2(110). | 2008 | Langmuir | pmid:18590297 |
| Wiemer AJ et al. | Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation. | 2008 | Bioorg. Med. Chem. | pmid:18308574 |
| Ohnishi S et al. | Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment. | 2008 | Drug Metab. Pharmacokinet. | pmid:18762717 |
| Berg ER et al. | Ion-pair interaction in pyridinium carboxylate solutions. | 2008 | J Phys Chem A | pmid:18189374 |
| Mascolo G et al. | Effectiveness of UV-based advanced oxidation processes for the remediation of hydrocarbon pollution in the groundwater: a laboratory investigation. | 2008 | J. Hazard. Mater. | pmid:17890002 |
| Liégault B et al. | Intramolecular Pd(II)-catalyzed oxidative biaryl synthesis under air: reaction development and scope. | 2008 | J. Org. Chem. | pmid:18543991 |
| Sun Y et al. | μ(3)-Oxido-hexa-μ(2)-pivalato-tris[(methanol-κO)cobalt(III)] chloride. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21578144 |
| Jacobson KA et al. | Development of selective agonists and antagonists of P2Y receptors. | 2009 | Purinergic Signal. | pmid:18600475 |
| Huang JK et al. | Effect of MK-886 on Ca2+ level and viability in PC3 human prostate cancer cells. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19371256 |
| Goossen LJ et al. | C(aryl)-O activation of aryl carboxylates in nickel-catalyzed biaryl syntheses. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19280618 |
| Alborés P and Rentschler E | A Co36 cluster assembled from the reaction of cobalt pivalate with 2,3-dicarboxypyrazine. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19890926 |