Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Seizures D012640 87 associated lipids
Dermatitis D003872 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

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Authors Title Published Journal PubMed Link
Biswas P et al. Synthesis, reactivities, and magnetostructural properties of FeIII, FeIII-O-FeIII, and ZnIIFeIII-O-FeIIIZnII complexes of a tetraiminodiphenolate macrocycle. 2006 Inorg Chem pmid:16749848
Ovcharenko V et al. Synthesis, structure, and magnetic properties of (6-9)-nuclear Ni(II) trimethylacetates and their heterospin complexes with nitroxides. 2006 Inorg Chem pmid:16813397
Barberán J et al. Update on the clinical utility and optimal use of cefditoren. 2012 Int J Gen Med pmid:22675264
Stefanucci A et al. Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control. 2011 Int J Mol Sci pmid:21686155
Cooper TG et al. Successful lowering of epididymal carnitine by administration of pivalate to rats. 1997 Int. J. Androl. pmid:9354188
Wang SS et al. Cleavage and deprotection of peptides on MBHA-resin with hydrogen bromide. 1992 Sep-Oct Int. J. Pept. Protein Res. pmid:1335998
Berkovitch-Luria G et al. Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways. 2012 Invest New Drugs pmid:21509470
Del Rosso JQ and Kircik L A Comprehensive Review of Clocortolone Pivalate 0.1% Cream: Structural Development, Formulation Characteristics, and Studies Supporting Treatment of Corticosteroid-responsive Dermatoses. 2012 J Clin Aesthet Dermatol pmid:22798972
Mazauric FX and Alligier B [Trial of tixocortol pivalate (Pivalone) in otorhinolaryngology]. 1978 J Fr Otorhinolaryngol Audiophonol Chir Maxillofac pmid:154555
Metges CC et al. Gas chromatography/combustion/isotope ratio mass spectrometric comparison of N-acetyl- and N-pivaloyl amino acid esters to measure 15N isotopic abundances in physiological samples: a pilot study on amino acid synthesis in the upper gastro-intestinal tract of minipigs. 1996 J Mass Spectrom pmid:8799283
Slusarski T et al. Electronic structure and magnetic properties of a molecular octanuclear chromium-based ring. 2011 J Nanosci Nanotechnol pmid:22400306
Xu W et al. Identification and characterization of three impurities in clocortolone pivalate. 2012 J Pharm Biomed Anal pmid:22264563
Wu DR et al. Additive free preparative chiral SFC separations of 2,2-dimethyl-3-aryl-propanoic acids. 2016 J Pharm Biomed Anal pmid:27522108
Hussain MA et al. Improvement of the oral bioavailability of naltrexone in dogs: a prodrug approach. 1987 J Pharm Sci pmid:3656096
Konishi M and Hashimoto H Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection. 1992 J Pharm Sci pmid:1432617
Giordano F et al. Crystal forms of piroxicam pivalate: preparation and characterization of two polymorphs. 1998 J Pharm Sci pmid:9523987
Suga K et al. Photocatalytic oxygenation of pivalic acid with molecular oxygen via photoinduced electron transfer using 10-methylacridinium ions. 2006 J Phys Chem A pmid:16539406
Berg ER et al. Ion-pair interaction in pyridinium carboxylate solutions. 2008 J Phys Chem A pmid:18189374
Greaves TL et al. Protic ionic liquids: physicochemical properties and behavior as amphiphile self-assembly solvents. 2008 J Phys Chem B pmid:18166036
Sasahara A et al. STM observation of a ruthenium dye adsorbed on a TiO2(110) surface. 2006 J Phys Chem B pmid:16526711