| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Kaitner B and Stilinović V | Conformational enantiomeric disorder in tripivaloylmethane. | 2007 | Acta Crystallogr C | pmid:17551202 |
| Cao G et al. | Bis[(1H-1,2,3-benzotriazol-1-yl)methyl 2,2-dimethyl-propano-ato-κN(3)]dichlorido-copper(II). | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22590111 |
| Xu S and Shen Y | (1H-1,2,3-Benzotriazol-1-yl)methyl 2,2-dimethyl-propano-ate. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22589933 |
| Yang G et al. | (E)-2-(4-tert-But-ylphen-yl)-2-cyano-1-(3-methyl-1-vinyl-1H-pyrazol-5-yl)vinyl 2,2-dimethyl-propano-ate. | 2012 | Acta Crystallogr Sect E Struct Rep Online | pmid:22259565 |
| Meng Q et al. | Di-μ-pivalato-κO,O':O';κO:O,O'-bis-[(methanol-κO)bis-(2,2,6,6-tetra-methylhepta-ne-3,5-dionato)praseo-dymium(III)]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:22219764 |
| Hyun MY et al. | catena-Poly[[tetra-aqua-[trans-1,2-bis-(4-pyrid-yl)ethene-κN:N']nickel(II)] dinitrate]. | 2011 | Acta Crystallogr Sect E Struct Rep Online | pmid:21753926 |
| Xu M et al. | (E)-2-(4-tert-Butyl-phen-yl)-1-(4-chloro-1-ethyl-3-methyl-1H-pyrazol-5-yl)-2-cyano-ethenyl 2,2-dimethyl-propano-ate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589554 |
| Gu XB et al. | tert-Butyl 6-amino-3,4-dihydro-2H-1,4-benzoxazine-4-carboxyl-ate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589552 |
| Lohier JF et al. | tert-Butyl 6-bromo-1,4-dimethyl-9H-carbazole-9-carboxyl-ate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21588291 |
| Gu XB | tert-Butyl 6-acetamido-3,4-dihydro-2H-1,4-benzoxazine-4-carboxyl-ate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21587577 |
| Ozair LN et al. | Tetra-kis(μ(2)-2,2-dimethyl-propanoato-κO,O')bis-[(pyridine-κN)copper(II)]: a monoclinic polymorph. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579064 |
| Chen XD et al. | Aqua-(1,10-phenanthroline-κN,N')bis-(trimethyl-acetato)-κO,O';κO-cobalt(II). | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21583436 |
| Thoss M et al. | (R)-Di-tert-butyl 1,1'-binaphthyl-2,2'-dicarboxyl-ate. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21581860 |
| Sun Y et al. | μ(3)-Oxido-hexa-μ(2)-pivalato-tris[(methanol-κO)cobalt(III)] chloride. | 2009 | Acta Crystallogr Sect E Struct Rep Online | pmid:21578144 |
| Xu WJ et al. | N-{N-[N-(1,1-Dimethyl-ethoxy-carbon-yl)-l-leuc-yl]-N-methyl-l-leuc-yl}-N-methyl-l-leucine benzyl ester. | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21581037 |
| Overgaard J et al. | Tetra-kis(μ-pivalato-κO:O')bis-[(2-methyl-pyridine-κN)iron(II)](Fe-Fe). | 2008 | Acta Crystallogr Sect E Struct Rep Online | pmid:21201879 |
| Zanelli U et al. | Selective depletion of mitochondrial glutathione content by pivalic acid and valproic acid in rat liver: possibility of a common mechanism. | 1996 | Adv. Exp. Med. Biol. | pmid:8794200 |
| Lelièvre V et al. | Correlation between binding activity, inhibition of lymphoblastic transformation and metabolism of tixocortol 21 pivalate in mouse thymocytes. | 1987 | Agents Actions | pmid:3500591 |
| Stanton BA | Characterization of apical and basolateral membrane conductances of rat inner medullary collecting duct. | 1989 | Am. J. Physiol. | pmid:2719119 |
| Dzielak DJ and Norman RA | Renal nerves are not necessary for onset or maintenance of DOC-salt hypertension in rats. | 1985 | Am. J. Physiol. | pmid:4061671 |
| Wagner CA et al. | Functional and pharmacological characterization of human Na(+)-carnitine cotransporter hOCTN2. | 2000 | Am. J. Physiol. Renal Physiol. | pmid:10966938 |
| Nishimura S et al. | Application of a surface plasmon resonance sensor to analyses of amine compounds with the use of a polymer film and an acid-base reaction. | 2002 | Anal Sci | pmid:11918182 |
| Rodemann T et al. | Isoelectric buffers for capillary electrophoresis. 2. Bismorpholine derivative of a carboxylic acid as a low molecular weight isoelectric buffer. | 2005 | Anal. Chem. | pmid:15623286 |
| Goossen LJ et al. | C(aryl)-O activation of aryl carboxylates in nickel-catalyzed biaryl syntheses. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19280618 |
| Li BJ et al. | Cross-coupling of aryl/alkenyl pivalates with organozinc reagents through nickel-catalyzed C-O bond activation under mild reaction conditions. | 2008 | Angew. Chem. Int. Ed. Engl. | pmid:19016280 |
| Shimasaki T et al. | Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20229558 |
| Alborés P and Rentschler E | A Co36 cluster assembled from the reaction of cobalt pivalate with 2,3-dicarboxypyrazine. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19890926 |
| Trost BM et al. | Palladium-catalyzed asymmetric allylic alkylation of 3-aryloxindoles with allylidene dipivalate: a useful enol pivalate product. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23335176 |
| Stanley CA | Carnitine deficiency disorders in children. | 2004 | Ann. N. Y. Acad. Sci. | pmid:15591002 |
| Totsuka K et al. | Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans. | 1992 | Antimicrob. Agents Chemother. | pmid:1503437 |
| Nakashima M et al. | Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores. | 1992 | Antimicrob. Agents Chemother. | pmid:1503438 |
| Shimizu K et al. | Carnitine status and safety after administration of S-1108, a new oral cephem, to patients. | 1993 | Antimicrob. Agents Chemother. | pmid:8517691 |
| Mizojiri K et al. | Disposition of S-1108, a new oral cephem antibiotic, and metabolic fate of pivalic acid liberated from [pivaloyl-14C]S-1108 in rats and dogs. | 1995 | Antimicrob. Agents Chemother. | pmid:7492083 |
| Probian C et al. | Anaerobic mineralization of quaternary carbon atoms: isolation of denitrifying bacteria on pivalic acid (2,2-dimethylpropionic acid). | 2003 | Appl. Environ. Microbiol. | pmid:12620885 |
| Rezanka T et al. | Biosynthesis and metabolic pathways of pivalic acid. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22790609 |
| Tamaru RD et al. | Comparison of ocular disposition of free pivalic acid and pivalic acid esterified in dipivefrin. | 1983 | Arch. Ophthalmol. | pmid:6347153 |
| Staatz WD et al. | Cytotoxicity of pivalylphenylephrine and pivalic acid to corneal endothelium. | 1980 | Arch. Ophthalmol. | pmid:7396784 |
| Wexler BC | Corticotropin stimulation of hypertensive rats with and without arteriosclerosis. | 1978 | Arch. Pathol. Lab. Med. | pmid:214053 |
| Maurer H and Kessler C | Identification and quantification of ethylene glycol and diethylene glycol in plasma using gas chromatography-mass spectrometry. | 1988 | Arch. Toxicol. | pmid:3190459 |
| Zanelli U et al. | Induction of peroxisomal beta-oxidation and P-450 4A-dependent activities by pivalic and trichloroacetic acid in rat liver and kidney. | 1996 | Arch. Toxicol. | pmid:8825670 |
| Reckers VR and Wendt H | [Multicentre-clinical trial of the novel corticosteroid diflucortolone valerate in the forms of cream, ointment and fatty ointment. Part I: Comparative study of diflucortolone valerate with fluocortolone, -capronate, -pivalate in a double-blind contralateral design with topical application (author's transl)]. | 1976 | Arzneimittelforschung | pmid:795433 |
| Goldberg I et al. | Dipivefrin: current concepts. | 1980 | Aust J Ophthalmol | pmid:7004425 |
| Peel CJ et al. | The importance of prolactin and the milking stimulus in the artificial induction of lactation in cows. | 1978 | Aust. J. Biol. Sci. | pmid:678223 |
| Fulkerson WJ and McDowell GH | Artificial induction of lactation in cattle by use of dexamethasone trimethylacetate. | 1975 | Aust. J. Biol. Sci. | pmid:1167131 |
| Fulkerson WJ et al. | Artificial induction of lactation in ewes: the role of prolactin. | 1975 | Aust. J. Biol. Sci. | pmid:1243818 |
| Fairclough RJ et al. | Dexamethasone concentrations in plasma and milk of cows following the injection of long- and short-acting dexamethasone esters. | 1981 | Aust. J. Biol. Sci. | pmid:7295211 |
| Johnston NE and Stewart JA | The effect of glucocorticoids and prematurity on absorption of colostral immunoglobulin in the calf. | 1986 | Aust. Vet. J. | pmid:3767799 |
| Bailey LF et al. | The use of dexamethasone trimethylacetate to advance parturition in dairy cows. | 1973 | Aust. Vet. J. | pmid:4777214 |
| Mansell PD et al. | Induction of parturition in dairy cattle and its effects on health and subsequent lactation and reproductive performance. | 2006 | Aust. Vet. J. | pmid:16958626 |