Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Seizures D012640 87 associated lipids
Dermatitis D003872 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

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Per page 10 20 50 100 | Total 272
Authors Title Published Journal PubMed Link
Wurm A et al. Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells. 2010 J. Neurochem. pmid:20002522
Witney TH et al. Preclinical evaluation of 3-18F-fluoro-2,2-dimethylpropionic acid as an imaging agent for tumor detection. 2014 J. Nucl. Med. pmid:25012458
Bianchi PB and Davis AT Sodium pivalate treatment reduces tissue carnitines and enhances ketosis in rats. 1991 J. Nutr. pmid:1941267
Nakajima H et al. Pivalate affects carnitine status but causes no severe metabolic changes in rat liver. 1996 J. Nutr. pmid:8648443
Bianchi PB and Davis AT beta-Hydroxybutyrate oxidation is reduced and hepatic balance of ketone bodies and free fatty acids is unaltered in carnitine-depleted, pivalate-treated rats. 1996 J. Nutr. pmid:8914959
Bianchi PB et al. Carnitine supplementation ameliorates the steatosis and ketosis induced by pivalate in rats. 1996 J. Nutr. pmid:8914960
Davis AT and Monroe TJ Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats. 2005 J. Nutr. pmid:15795431
Nakamura T et al. Effect of d,l-alpha-tocopheryl esters on vitamin E-deficient rats. 1978 J. Nutr. Sci. Vitaminol. pmid:731332
Demory E et al. Fast Pd- and Pd/Cu-catalyzed direct C-H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters. 2012 J. Org. Chem. pmid:22946756
Rao ChB et al. An efficient protocol for alcohol protection under solvent- and catalyst-free conditions. 2009 J. Org. Chem. pmid:19839567