| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zizzo MG et al. | Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release. | 2007 | Neuroscience | pmid:17997228 |
| Rispoli V et al. | Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert. | 2004 | Neurosci. Lett. | pmid:15036629 |
| Quintas C et al. | The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues. | 2009 | Neurochem. Int. | pmid:19447154 |
| Shan Y et al. | Rapid acyl migration between pyrogallyl 1,2- and 1,3-dipivaloates. | 2012 | Nat Prod Commun | pmid:22545406 |
| MacDiarmid SC | Betamethasone alcohol suspensions for the induction of parturition in dairy cows: a comparison with dexamethasone trimethyl acetate. | 1979 | N Z Vet J | pmid:292913 |
| Xu S et al. | Transport of L-carnitine in human corneal and conjunctival epithelial cells. | 2010 | Mol. Vis. | pmid:21045919 |
| Boemer F et al. | Surprising causes of C5-carnitine false positive results in newborn screening. | 2014 | Mol. Genet. Metab. | pmid:24291264 |
| Villa G et al. | Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. | 2010 | Mol Pain | pmid:21143950 |
| Rohwerder T and Müller RH | Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon. | 2010 | Microb. Cell Fact. | pmid:20184738 |
| Broderick TL et al. | Fatty acid oxidation and cardiac function in the sodium pivalate model of secondary carnitine deficiency. | 1995 | Metab. Clin. Exp. | pmid:7723673 |
| Abrahamsson K et al. | Pivalic acid-induced carnitine deficiency and physical exercise in humans. | 1996 | Metab. Clin. Exp. | pmid:8969283 |
| Yahyaoui R et al. | [C5-carnitine false positive results in newborn screening: what is the cause?]. | 2015 | Med Clin (Barc) | pmid:24889749 |
| Fagerholm AE et al. | Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C. | 2010 | Mar Drugs | pmid:20161975 |
| Morris GS et al. | Sodium pivalate reduces cardiac carnitine content and increases glucose oxidation without affecting cardiac functional capacity. | 1995 | Life Sci. | pmid:7475977 |
| Ricciolini R et al. | The effect of pivalate treatment of pregnant rats on body mass and insulin levels in the adult offspring. | 2001 | Life Sci. | pmid:11665835 |
| Takahashi Y et al. | A case of sudden unexpected infant death involving a homozygotic twin with the thermolabile CPT2 variant, accompanied by rotavirus infection and treatment with an antibiotic containing pivalic acid. | 2016 | Leg Med (Tokyo) | pmid:27591533 |
| Kotal A et al. | Ultrasound-induced in situ formation of coordination organogels from isobutyric acids and zinc oxide nanoparticles. | 2010 | Langmuir | pmid:20020763 |
| Ikeda M et al. | Scanning tunneling microscopy study of black dye and deoxycholic acid adsorbed on a rutile TiO2(110). | 2008 | Langmuir | pmid:18590297 |
| Holme E et al. | Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. | 1989 | Lancet | pmid:2570185 |
| Melegh B | Carnitine supplementation in pivampicillin treatment. | 1989 | Lancet | pmid:2572813 |