Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Seizures D012640 87 associated lipids
Dermatitis D003872 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

Download all related citations
Per page 10 20 50 100 | Total 272
Authors Title Published Journal PubMed Link
Barroca N and Jacquinet JC An access to various sulfation patterns in dermatan sulfate: chemical syntheses of sulfoforms of trisaccharide methyl glycosides. 2002 Carbohydr. Res. pmid:11950464
Overgaard J et al. Host-guest chemistry of the chromium-wheel complex [Cr8F8(tBuCO2)16]: prediction of inclusion capabilities by using an electrostatic potential distribution determined by modeling synchrotron X-ray structure factors at 16 K. 2002 Chemistry pmid:12391657
Niezen JH et al. The effect of feeding sulla (Hedysarum coronarium) or lucerne (Medicago sativa) on lamb parasite burdens and development of immunity to gastrointestinal nematodes. 2002 Vet. Parasitol. pmid:11934463
Bursten BE et al. Oxalate-bridged complexes of dimolybdenum and ditungsten supported by pivalate ligands: ((t)BuCO(2))(3)M(2)(mu-O(2)CCO(2))M(2)(O(2)C(t)Bu)(3). Correlation of the solid-state, molecular, and electronic structures with Raman, resonance Raman, and electronic spectral data. 2002 J. Am. Chem. Soc. pmid:11902897
Mitani MM et al. Kinetics and products of reactions of MTBE with ozone and ozone/hydrogen peroxide in water. 2002 J. Hazard. Mater. pmid:11744205
Li C et al. In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat. 2003 J. Pharmacol. Exp. Ther. pmid:12649376
Färber K et al. Selective desensitization of jasmonate- and pH-dependent signaling in the induction of benzophenanthridine biosynthesis in cells of Eschscholzia californica. 2003 Phytochemistry pmid:12620362
Probian C et al. Anaerobic mineralization of quaternary carbon atoms: isolation of denitrifying bacteria on pivalic acid (2,2-dimethylpropionic acid). 2003 Appl. Environ. Microbiol. pmid:12620885
Spino C et al. A stereodivergent approach to chiral nonracemic N-protected alpha,alpha-dialkylated amino acids. 2003 J. Am. Chem. Soc. pmid:14518992
Aromí G et al. Synthetic and structural studies of cobalt-pivalate complexes. 2003 Chemistry pmid:14562332
Li C et al. In vitro studies on the chemical reactivity of 2,4-dichlorophenoxyacetyl-S-acyl-CoA thioester. 2003 Toxicol. Appl. Pharmacol. pmid:12649042
Carlsson H et al. Structural and functional models of the active site of zinc phosphotriesterase. 2004 Inorg Chem pmid:15332820
Solano-Serena F et al. Degradation of isooctane by Mycobacterium austroafricanum IFP 2173: growth and catabolic pathway. 2004 J. Appl. Microbiol. pmid:15281945
Stanley CA Carnitine deficiency disorders in children. 2004 Ann. N. Y. Acad. Sci. pmid:15591002
Chaboussant G et al. Nickel pivalate complexes: structural variations and magnetic susceptibility and inelastic neutron scattering studies. 2004 Dalton Trans pmid:15514763
Christian P et al. Synthesis and studies of a trinuclear Mn(II) carboxylate complex. 2004 Dalton Trans pmid:15303171
Rispoli V et al. Electroencephalographic effects induced by choline pivaloyl esters in scopolamine-treated or nucleus basalis magnocellularis lesioned rats. 2004 Pharmacol. Biochem. Behav. pmid:15301920
Qian H et al. Platinum-catalyzed intramolecular hydroalkoxylation of gamma- and delta-hydroxy olefins to form cyclic ethers. 2004 J. Am. Chem. Soc. pmid:15291546
Christian P et al. Structural, magnetic and DFT studies of a hydroxide-bridged [Cr8] wheel. 2004 Dalton Trans pmid:15252595
Rispoli V et al. Choline pivaloyl esters improve in rats cognitive and memory performances impaired by scopolamine treatment or lesions of the nucleus basalis of Meynert. 2004 Neurosci. Lett. pmid:15036629
Goossen LJ and Rodríguez N A mild and efficient protocol for the conversion of carboxylic acids to olefins by a catalytic decarbonylative elimination reaction. 2004 Chem. Commun. (Camb.) pmid:15010800
Zídek Z et al. Cytotoxicity of pivoxil esters of antiviral acyclic nucleoside phosphonates: adefovir dipivoxil versus adefovir. 2005 Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub pmid:16601779
Davis AT and Monroe TJ Carnitine deficiency and supplementation do not affect the gene expression of carnitine biosynthetic enzymes in rats. 2005 J. Nutr. pmid:15795431
Wu M et al. Synthesis of 9-[1-(substituted)-3-(phosphonomethoxy)propyl]adenine derivatives as possible antiviral agents. 2005 Nucleosides Nucleotides Nucleic Acids pmid:16438034
Zhou JH et al. Syntheses, structures, and magnetic properties of unusual nonlinear polynuclear copper(II) complexes containing derivatives of 1,2,4-triazole and pivalate ligands. 2005 Inorg Chem pmid:16241151
Kumar P et al. [131I]Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice. 2005 Nucl. Med. Biol. pmid:16026712
Rajaraman G et al. Theoretical studies on di- and tetra-nuclear Ni pivalate complexes. 2005 Chem. Commun. (Camb.) pmid:15959582
Wang X et al. Direct C-arylation of free (NH)-indoles and pyrroles catalyzed by Ar-Rh(III) complexes assembled in situ. 2005 J. Am. Chem. Soc. pmid:15810815
Rodemann T et al. Isoelectric buffers for capillary electrophoresis. 2. Bismorpholine derivative of a carboxylic acid as a low molecular weight isoelectric buffer. 2005 Anal. Chem. pmid:15623286
Biswas P et al. Synthesis, reactivities, and magnetostructural properties of FeIII, FeIII-O-FeIII, and ZnIIFeIII-O-FeIIIZnII complexes of a tetraiminodiphenolate macrocycle. 2006 Inorg Chem pmid:16749848
Milios CJ et al. 1,1,1-Tris(hydroxymethyl)propane in manganese carboxylate chemistry: synthesis, structure and magnetic properties of a mixed-valence [MnIII4MnII4] cluster featuring the novel [MnIII4MnII4(mu3-OR)6(mu2-OR)8]6+ core. 2006 Dalton Trans pmid:16365649
Lee J et al. 2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands. 2006 Bioorg. Med. Chem. pmid:16297629
Chakraborti AK and Shivani S Magnesium bistrifluoromethanesulfonimide as a new and efficient acylation catalyst. 2006 J. Org. Chem. pmid:16839166
Yamaguchi T et al. Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats. 2006 Toxicol. Appl. Pharmacol. pmid:16430936
Sibi MP and Zimmerman J Pyrones to pyrans: enantioselective radical additions to acyloxy pyrones. 2006 J. Am. Chem. Soc. pmid:17031933
Suga K et al. Photocatalytic oxygenation of pivalic acid with molecular oxygen via photoinduced electron transfer using 10-methylacridinium ions. 2006 J Phys Chem A pmid:16539406
Broderick TL Hypocarnitinaemia induced by sodium pivalate in the rat is associated with left ventricular dysfunction and impaired energy metabolism. 2006 Drugs R D pmid:16752941
Okamura N et al. Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid. 2006 Pharm. Res. pmid:16826461
Lafrance M and Fagnou K Palladium-catalyzed benzene arylation: incorporation of catalytic pivalic acid as a proton shuttle and a key element in catalyst design. 2006 J. Am. Chem. Soc. pmid:17177387
Shanmugam M et al. Studies of a molecular hourglass: synthesis and magnetic characterisation of a cyclic dodecanuclear {Cr10Cu2} complex. 2006 Chemistry pmid:17009364
Sugiura T et al. 1D helical polymeric chain with a pseudo-5(3) screw axis formed by cuprophilicity. synthesis and crystal structure of copper(I) pivalate. 2006 Inorg Chem pmid:16961347
Mansell PD et al. Induction of parturition in dairy cattle and its effects on health and subsequent lactation and reproductive performance. 2006 Aust. Vet. J. pmid:16958626
Ovcharenko V et al. Synthesis, structure, and magnetic properties of (6-9)-nuclear Ni(II) trimethylacetates and their heterospin complexes with nitroxides. 2006 Inorg Chem pmid:16813397
Weis R et al. Antiplasmodial and antitrypanosomal activity of new esters and ethers of 4-dialkylaminobicyclo[2.2.2]octan-2-ols. 2006 Eur J Pharm Sci pmid:16713699
Wittick LM et al. New mixed-valence MnII2MnIII2 clusters exhibiting an unprecedented MnII/III oxidation state distribution in their magnetically coupled cores. 2006 Dalton Trans pmid:16538272
Sasahara A et al. STM observation of a ruthenium dye adsorbed on a TiO2(110) surface. 2006 J Phys Chem B pmid:16526711
Zizzo MG et al. Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon. 2007 Br. J. Pharmacol. pmid:17351663
Zizzo MG et al. Inhibitory purinergic transmission in mouse caecum: role for P2Y1 receptors as prejunctional modulators of ATP release. 2007 Neuroscience pmid:17997228
Milios CJ et al. Toward a magnetostructural correlation for a family of Mn6 SMMs. 2007 J. Am. Chem. Soc. pmid:17887755
Cornwell PD and Ulrich RG Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles. 2007 Toxicol Pathol pmid:17654398