Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Seizures D012640 87 associated lipids
Dermatitis D003872 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

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Authors Title Published Journal PubMed Link
Rohwerder T and Müller RH Biosynthesis of 2-hydroxyisobutyric acid (2-HIBA) from renewable carbon. 2010 Microb. Cell Fact. pmid:20184738
Villa G et al. Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus. 2010 Mol Pain pmid:21143950
Xu S et al. Transport of L-carnitine in human corneal and conjunctival epithelial cells. 2010 Mol. Vis. pmid:21045919
Fagerholm AE et al. Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C. 2010 Mar Drugs pmid:20161975
Andó RD et al. A comparative analysis of the activity of ligands acting at P2X and P2Y receptor subtypes in models of neuropathic, acute and inflammatory pain. 2010 Br. J. Pharmacol. pmid:20136836
Xu M et al. (E)-2-(4-tert-Butyl-phen-yl)-1-(4-chloro-1-ethyl-3-methyl-1H-pyrazol-5-yl)-2-cyano-ethenyl 2,2-dimethyl-propano-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589554
Gu XB et al. tert-Butyl 6-amino-3,4-dihydro-2H-1,4-benzoxazine-4-carboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589552
Lohier JF et al. tert-Butyl 6-bromo-1,4-dimethyl-9H-carbazole-9-carboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588291
Gu XB tert-Butyl 6-acetamido-3,4-dihydro-2H-1,4-benzoxazine-4-carboxyl-ate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21587577
Ozair LN et al. Tetra-kis(μ(2)-2,2-dimethyl-propanoato-κO,O')bis-[(pyridine-κN)copper(II)]: a monoclinic polymorph. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579064
Walling HW and Swick BL Update on the management of chronic eczema: new approaches and emerging treatment options. 2010 Clin Cosmet Investig Dermatol pmid:21437065
Wurm A et al. Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells. 2010 J. Neurochem. pmid:20002522
Kotal A et al. Ultrasound-induced in situ formation of coordination organogels from isobutyric acids and zinc oxide nanoparticles. 2010 Langmuir pmid:20020763
Shimasaki T et al. Nickel-catalyzed amination of aryl pivalates by the cleavage of aryl C-O bonds. 2010 Angew. Chem. Int. Ed. Engl. pmid:20229558
Abbas G et al. Series of isostructural planar lanthanide complexes [Ln(III)4(mu3-OH)2(mdeaH)2(piv)8] with single molecule magnet behavior for the Dy4 analogue. 2010 Inorg Chem pmid:20704320
Liu TF et al. An alcoholysis route to a Cu16 cluster, and the influence of the alcohol. 2010 Dalton Trans pmid:20354607
Cox AD et al. Investigating the candidacy of LPS-based glycoconjugates to prevent invasive meningococcal disease: chemical strategies to prepare glycoconjugates with good carbohydrate loading. 2010 Glycoconj. J. pmid:20340043
Sun Y et al. μ(3)-Oxido-hexa-μ(2)-pivalato-tris[(methanol-κO)cobalt(III)] chloride. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21578144
Jacobson KA et al. Development of selective agonists and antagonists of P2Y receptors. 2009 Purinergic Signal. pmid:18600475
Alborés P and Rentschler E A Co36 cluster assembled from the reaction of cobalt pivalate with 2,3-dicarboxypyrazine. 2009 Angew. Chem. Int. Ed. Engl. pmid:19890926