| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Wurm A et al. | Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells. | 2010 | J. Neurochem. | pmid:20002522 |
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| Shoman ME et al. | Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties. | 2011 | J. Med. Chem. | pmid:21247168 |
| Berkovitch G et al. | Novel multifunctional acyloxyalkyl ester prodrugs of 5-aminolevulinic acid display improved anticancer activity independent and dependent on photoactivation. | 2008 | J. Med. Chem. | pmid:19007111 |
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| Will KW et al. | Quantification and evidence for mechanically metered release of pygidial secretions in formic acid-producing carabid beetles. | 2010 | J. Insect Sci. | pmid:20575743 |
| Rasmussen J et al. | Primary carnitine deficiency and pivalic acid exposure causing encephalopathy and fatal cardiac events. | 2013 | J. Inherit. Metab. Dis. | pmid:22566287 |
| Mascolo G et al. | Effectiveness of UV-based advanced oxidation processes for the remediation of hydrocarbon pollution in the groundwater: a laboratory investigation. | 2008 | J. Hazard. Mater. | pmid:17890002 |
| Mitani MM et al. | Kinetics and products of reactions of MTBE with ozone and ozone/hydrogen peroxide in water. | 2002 | J. Hazard. Mater. | pmid:11744205 |
| Schmidt J et al. | Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3. | 2011 | J. Biol. Chem. | pmid:21220428 |
| Cracan V and Banerjee R | Novel coenzyme B12-dependent interconversion of isovaleryl-CoA and pivalyl-CoA. | 2012 | J. Biol. Chem. | pmid:22167181 |
| Blanton MP et al. | Examining the noncompetitive antagonist-binding site in the ion channel of the nicotinic acetylcholine receptor in the resting state. | 2000 | J. Biol. Chem. | pmid:10652341 |
| Solano-Serena F et al. | Degradation of isooctane by Mycobacterium austroafricanum IFP 2173: growth and catabolic pathway. | 2004 | J. Appl. Microbiol. | pmid:15281945 |
| Ferrer Flegeau E et al. | Autocatalysis for C-H bond activation by ruthenium(II) complexes in catalytic arylation of functional arenes. | 2011 | J. Am. Chem. Soc. | pmid:21604765 |
| Li G et al. | Au-catalyzed synthesis of (1Z,3E)-2-pivaloxy-1,3-dienes from propargylic pivalates. | 2008 | J. Am. Chem. Soc. | pmid:18311985 |
| Sibi MP and Zimmerman J | Pyrones to pyrans: enantioselective radical additions to acyloxy pyrones. | 2006 | J. Am. Chem. Soc. | pmid:17031933 |
| Quasdorf KW et al. | Cross-coupling reactions of aryl pivalates with boronic acids. | 2008 | J. Am. Chem. Soc. | pmid:18839946 |
| Milios CJ et al. | Toward a magnetostructural correlation for a family of Mn6 SMMs. | 2007 | J. Am. Chem. Soc. | pmid:17887755 |
| Qian H et al. | Platinum-catalyzed intramolecular hydroalkoxylation of gamma- and delta-hydroxy olefins to form cyclic ethers. | 2004 | J. Am. Chem. Soc. | pmid:15291546 |