| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Dermatitis | D003872 | 30 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
Pivalic acid
Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.
Cross Reference
Introduction
To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Pivalic acid?
Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Pivalic acid
PubChem Associated disorders and diseases
What pathways are associated with Pivalic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Pivalic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Pivalic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Pivalic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with Pivalic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Pivalic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Holme E et al. | Effects of pivalic acid-containing prodrugs on carnitine homeostasis and on response to fasting in children. | 1992 | Scand. J. Clin. Lab. Invest. | pmid:1514015 |
| Konishi M and Hashimoto H | Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection. | 1992 | J Pharm Sci | pmid:1432617 |
| Totsuka K et al. | Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans. | 1992 | Antimicrob. Agents Chemother. | pmid:1503437 |
| Nakashima M et al. | Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores. | 1992 | Antimicrob. Agents Chemother. | pmid:1503438 |
| Wang SS et al. | Cleavage and deprotection of peptides on MBHA-resin with hydrogen bromide. | 1992 Sep-Oct | Int. J. Pept. Protein Res. | pmid:1335998 |
| Fujii R et al. | [Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients]. | 1993 | Jpn J Antibiot | pmid:8254895 |
| Shimizu K et al. | Carnitine status and safety after administration of S-1108, a new oral cephem, to patients. | 1993 | Antimicrob. Agents Chemother. | pmid:8517691 |
| Melegh B et al. | Preferential elimination of pivalate with supplemental carnitine via formation of pivaloylcarnitine in man. | 1993 | Xenobiotica | pmid:8310709 |
| Abrahamsson K et al. | Impaired ketogenesis in carnitine depletion caused by short-term administration of pivalic acid prodrug. | 1994 | Biochem. Med. Metab. Biol. | pmid:7917463 |
| Morris GS et al. | Sodium pivalate reduces cardiac carnitine content and increases glucose oxidation without affecting cardiac functional capacity. | 1995 | Life Sci. | pmid:7475977 |