Platelet activating factor

Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Platelet activating factor, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Platelet activating factor?

Platelet activating factor is suspected in Ischemia, Pleurisy, Atherosclerosis, Inflammatory disorder, Retinal Diseases, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Platelet activating factor

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hypercalcemia D006934 13 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Infertility, Male D007248 11 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Brain Injuries D001930 4 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteonecrosis D010020 5 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Pulmonary Edema D011654 23 associated lipids
Coronary Disease D003327 70 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Osteosarcoma D012516 50 associated lipids
Rhinitis D012220 10 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Asphyxia Neonatorum D001238 4 associated lipids
Melanoma D008545 69 associated lipids
Asthma D001249 52 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Peritonitis D010538 38 associated lipids
Hemorrhage D006470 15 associated lipids
Proteinuria D011507 30 associated lipids
Spasm D013035 5 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Arteriosclerosis D001161 86 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Thalassemia D013789 8 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Cholestasis D002779 23 associated lipids
Fibrosis D005355 23 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Multiple Sclerosis D009103 13 associated lipids
Glomerulonephritis D005921 35 associated lipids
Nervous System Diseases D009422 37 associated lipids
Psoriasis D011565 47 associated lipids
Brain Edema D001929 20 associated lipids
Leukopenia D007970 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Burns, Inhalation D002059 4 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Fetal Weight D020567 12 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Stroke D020521 32 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemia D007511 18 associated lipids
Colonic Diseases D003108 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Platelet activating factor

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Platelet activating factor?

Related references are published most in these journals:

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What functions are associated with Platelet activating factor?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Platelet activating factor?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Platelet activating factor?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Platelet activating factor?

Knock-out

Knock-out are used in the study 'A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.' (Leary PJ et al., 2008).

Mouse Model

Mouse Model are used in the study 'A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.' (Cheng L et al., 2009).

Transgenic Model

Transgenic Model are used in the study 'Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons.' (Ryan SD et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Platelet activating factor

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Per page 10 20 50 100 | Total 8526
Authors Title Published Journal PubMed Link
Leslie CC and Detty DM Arachidonic acid turnover in response to lipopolysaccharide and opsonized zymosan in human monocyte-derived macrophages. 1986 Biochem. J. pmid:3098232
Pritchard PH The degradation of platelet-activating factor by high-density lipoprotein in rat plasma. Effect of ethynyloestradiol administration. 1987 Biochem. J. pmid:3689334
Hallam TJ et al. Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2. 1984 Biochem. J. pmid:6426464
Hill CE and Olson MS Stimulation of uric acid release from the perfused rat liver by platelet activating factor or potassium. 1987 Biochem. J. pmid:3689345
Baldi E et al. Stimulation of platelet-activating factor synthesis by progesterone and A23187 in human spermatozoa. 1993 Biochem. J. pmid:8503848
Salari H et al. Translocation-independent activation of protein kinase C by platelet-activating factor, thrombin and prostacyclin. Lack of correlation with polyphosphoinositide hydrolysis in rabbit platelets. 1990 Biochem. J. pmid:2160234
Seifert R et al. Activation of superoxide formation and lysozyme release in human neutrophils by the synthetic lipopeptide Pam3Cys-Ser-(Lys)4. Involvement of guanine-nucleotide-binding proteins and synergism with chemotactic peptides. 1990 Biochem. J. pmid:2160237
MacIntyre DE and Pollock WK Platelet-activating factor stimulates phosphatidylinositol turnover in human platelets. 1983 Biochem. J. pmid:6411067
Tou J et al. Accumulation of phosphatidic acid mass and increased de novo synthesis of glycerolipids in platelet-activating-factor-activated human neutrophils. 1991 Biochem. J. pmid:1662484
Wang H et al. Regulation of platelet-activating factor receptor gene expression in vivo by endotoxin, platelet-activating factor and endogenous tumour necrosis factor. 1997 Biochem. J. pmid:9065783
Triggiani M et al. Factors that influence the proportions of platelet-activating factor and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine synthesized by the mast cell. 1992 Biochem. J. pmid:1530582
Gómez-Cambronero J et al. The role of calcium ions in the process of acetyltransferase activation during the formation of platelet-activating factor (PAF-acether). 1984 Biochem. J. pmid:6146309
Tsoukatos DC et al. Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein. 2001 Biochem. J. pmid:11439095
McKean ML and Silver MJ Phospholipid biosynthesis in human platelets. The acylation of lyso-platelet-activating factor. 1985 Biochem. J. pmid:3919710
Kloprogge E and Akkerman JW Binding kinetics of PAF-acether (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) to intact human platelets. 1984 Biochem. J. pmid:6150705
Altin JG and Bygrave FL Prostaglandin F2 alpha and the thromboxane A2 analogue ONO-11113 stimulate Ca2+ fluxes and other physiological responses in rat liver. Further evidence that prostanoids may be involved in the action of arachidonic acid and platelet-activating factor. 1988 Biochem. J. pmid:3128268
Chao W et al. Biosynthesis of platelet-activating factor by cultured rat Kupffer cells stimulated with calcium ionophore A23187. 1989 Biochem. J. pmid:2494988
O'Flaherty JT et al. Roles of Ca2+ in human neutrophil responses to receptor agonists. 1991 Biochem. J. pmid:1651699
Dohi T et al. Calcium-dependent biosynthesis of platelet-activating factor by submandibular gland cells. 1991 Biochem. J. pmid:1645529
Cluzel M et al. Dynamics of platelet-activating-factor release and uptake in a human neutrophil suspension. 1991 Biochem. J. pmid:1898338
Murphy CT and Westwick J Role of type 1 and type 2A phosphatases in signal transduction of platelet-activating-factor-stimulated rabbit platelets. 1994 Biochem. J. pmid:8042999
DiCorleto PE and de la Motte CA Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway. 1989 Biochem. J. pmid:2513808
O'Flaherty JT et al. Regulation of platelet-activating-factor receptors and the desensitization response in polymorphonuclear neutrophils. 1992 Biochem. J. pmid:1332696
Chao W et al. Metabolism of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) by cultured rat Kupffer cells. 1989 Biochem. J. pmid:2775221
Dulioust A et al. Biosynthesis of paf-acether. Paf-acether but not leukotriene C4 production is impaired in cultured macrophages. 1989 Biochem. J. pmid:2513801
Winkler JD et al. Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil. 1993 Biochem. J. pmid:8387780
Rogers JE et al. Solubilization of a functionally active platelet-activating factor receptor from rabbit platelets. 1991 Biochem. J. pmid:1654881
Hii CS et al. Basal and phorbol-ester-stimulated turnover of phosphatidylcholine in HeLa cells involve different pathways. 1992 Biochem. J. pmid:1335237
Snyder F Platelet-activating factor: the biosynthetic and catabolic enzymes. 1995 Biochem. J. pmid:7848265
Touqui L et al. Human platelets stimulated by thrombin produce platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when the degrading enzyme acetyl hydrolase is blocked. 1985 Biochem. J. pmid:4052028
Houslay MD et al. Platelet activating factor and U44069 stimulate a GTPase activity in human platelets which is distinct from the guanine nucleotide regulatory proteins, Ns and Ni. 1986 Biochem. J. pmid:3013161
Halenda SP and Rehm AG Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells. 1990 Biochem. J. pmid:2159285
Kjeldsen L et al. Subcellular localization and release of human neutrophil gelatinase, confirming the existence of separate gelatinase-containing granules. 1992 Biochem. J. pmid:1332677
Grigg ME et al. Characterization of a platelet-activating factor acetylhydrolase secreted by the nematode parasite Nippostrongylus brasiliensis. 1996 Biochem. J. pmid:8713083
Yousufzai SY and Abdel-Latif AA Effects of platelet-activating factor on the release of arachidonic acid and prostaglandins by rabbit iris smooth muscle. Inhibition by calcium channel antagonists. 1985 Biochem. J. pmid:3927898
Schwaner I et al. Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways. 1992 Biochem. J. pmid:1310589
Tran K et al. Vitamin E enhances the acylation of 1-O-alkyl-sn-glycero-3-phosphocholine in human endothelial cells. 1994 Biochem. J. pmid:8129709
Gandhi CR et al. A comparative study of endothelin- and platelet-activating-factor-mediated signal transduction and prostaglandin synthesis in rat Kupffer cells. 1992 Biochem. J. pmid:1310601
Montero M et al. Control of plasma-membrane Ca2+ entry by the intracellular Ca2+ stores. Kinetic evidence for a short-lived mediator. 1992 Biochem. J. pmid:1463455
Hashizume T et al. Sphingosine enhances platelet aggregation through an increase in phospholipase C activity by a protein kinase C-independent mechanism. 1992 Biochem. J. pmid:1540140
Bauldry SA and Wooten RE Induction of cytosolic phospholipase A2 activity by phosphatidic acid and diglycerides in permeabilized human neutrophils: interrelationship between phospholipases D and A2. 1997 Biochem. J. pmid:9065750
Joly F et al. Biosynthesis of paf-acether. Activators of protein kinase C stimulate cultured mast cell acetyltransferase without stimulating paf-acether synthesis. 1990 Biochem. J. pmid:2146953
Fouda SI et al. Effect of lipopolysaccharide on mitogen-activated protein kinases and cytosolic phospholipase A2. 1995 Biochem. J. pmid:8948437
Tao W et al. Arachidonic acid release in rabbit neutrophils. 1989 Biochem. J. pmid:2494986
Vallance SJ et al. Granulocyte-macrophage colony-stimulating factor can stimulate macrophage proliferation via persistent activation of Na+/H+ antiport. Evidence for two distinct roles for Na+/H+ antiport activation. 1990 Biochem. J. pmid:2154185
Kimura K et al. Different preparations of zymosan induce glycogenolysis independently in the perfused rat liver. Involvement of mannose receptors, peptide-leukotrienes and prostaglandins. 1992 Biochem. J. pmid:1317164
Chau LY et al. Agonist-induced down-regulation of platelet-activating factor receptor gene expression in U937 cells. 1994 Biochem. J. pmid:7519853
Dunlop ME and Larkins RG Insulin-dependent contractility of glomerular mesangial cells in response to angiotensin II, platelet-activating factor and endothelin is attenuated by prostaglandin E2. 1990 Biochem. J. pmid:2268285
Montero M et al. Agonist-induced Ca2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores. 1991 Biochem. J. pmid:1906712
Valone FH and Johnson B Modulation of platelet-activating-factor-induced calcium influx and intracellular calcium release in platelets by phorbol esters. 1987 Biochem. J. pmid:3322269
Liu B et al. Prolonged activation of phospholipase D in Chinese hamster ovary cells expressing platelet-activating-factor receptor lacking cytoplasmic C-terminal tail. 1997 Biochem. J. pmid:9355758
Herbert JM Characterization of specific binding sites of 3H-labelled platelet-activating factor ([3H]PAF) and a new antagonist, [3H]SR 27417, on guinea-pig tracheal epithelial cells. 1992 Biochem. J. pmid:1318021
Raggers RJ et al. Multidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factor. 2001 Biochem. J. pmid:11463358
Garcia MC et al. Biosynthesis of platelet-activating factor (PAF) in human polymorphonuclear leucocytes. The role of lyso-PAF disposal and free arachidonic acid. 1990 Biochem. J. pmid:1693077
Huang SJ et al. Platelet-activating factor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate stimulates the production of reactive oxygen intermediates in macrophages. 1988 Biochem. J. pmid:2833227
van Willigen G and Akkerman JW Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets. 1991 Biochem. J. pmid:1846526
Church DJ et al. Protein kinase C-mediated phospholipase A2 activation, platelet-activating factor generation and prostacyclin release in spontaneously beating rat cardiomyocytes. 1993 Biochem. J. pmid:8452537
Chao W and Olson MS Platelet-activating factor: receptors and signal transduction. 1993 Biochem. J. pmid:8391253
Murphy CT and Westwick J Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional responses. 1992 Biochem. J. pmid:1567363
Garcia MC et al. Metabolism of platelet-activating factor in human haematopoietic cell lines. Differences between myeloid and lymphoid cells. 1991 Biochem. J. pmid:1847616
van Willigen G et al. Exposure of ligand-binding sites on platelet integrin alpha IIB/beta 3 by phosphorylation of the beta 3 subunit. 1996 Biochem. J. pmid:8615768
Pelosin JM et al. Production of platelet-activating factor is a component of the angiotensin II-protein kinase C activation pathway in bovine adrenocortical cells. 1991 Biochem. J. pmid:1883337
Sebaldt RJ et al. Quantification of contributions of phospholipid precursors to diradylglycerols in stimulated mononuclear phagocytes. 1992 Biochem. J. pmid:1599420
Churchill L et al. Interaction of platelet-activating factor with cultured guinea pig tracheal epithelial cells. 1991 Biochem. J. pmid:2064601
Tripathi YB et al. Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells. 1992 Biochem. J. pmid:1382409
Krump E et al. Leukotriene synthesis in calcium-depleted human neutrophils: arachidonic acid release correlates with calcium influx. 1995 Biochem. J. pmid:7654211
Evans RD et al. Metabolic effects of platelet-activating factor in rats in vivo. Stimulation of hepatic glycogenolysis and lipogenesis. 1990 Biochem. J. pmid:2165397
Bushfield M et al. Inhibition of platelet-activating-factor-induced human platelet activation by prostaglandin D2. Differential sensitivity of platelet transduction processes and functional responses to inhibition by cyclic AMP. 1985 Biochem. J. pmid:3002327
Altin JG et al. Evidence that Ca2+ fluxes and respiratory, glycogenolytic and vasoconstrictive effects induced by the action of platelet-activating factor and L-alpha-lysophosphatidylcholine in the perfused rat liver are mediated by products of the cyclo-oxygenase pathway. 1987 Biochem. J. pmid:3117040
Evans RD et al. Effects of platelet-activating factor on lipid metabolism in rats in vivo. Origin of the hypertriglyceridaemia. 1991 Biochem. J. pmid:1747129
Kloprogge E and Akkerman JW Platelet-activating factor (PAF-acether) induces high- and low-affinity binding of fibrinogen to human platelets via independent mechanisms. 1986 Biochem. J. pmid:3101672
Burgers JA and Akkerman JW Regulation of the receptor for platelet-activating factor on human platelets. 1993 Biochem. J. pmid:8385926
Touqui L et al. The role of Ca2+ in regulating the catabolism of PAF-acether (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in rabbit platelets. 1987 Biochem. J. pmid:3109377
Rice SQ et al. Expression, purification and characterization of a human serine-dependent phospholipase A2 with high specificity for oxidized phospholipids and platelet activating factor. 1998 Biochem. J. pmid:9494101
Wu J et al. Intestinal alkaline sphingomyelinase hydrolyses and inactivates platelet-activating factor by a phospholipase C activity. 2006 Biochem. J. pmid:16255717
Soubeyrand S et al. Phospholipase A2 from bovine seminal plasma is a platelet-activating factor acetylhydrolase. 1998 Biochem. J. pmid:9405273
Coffer PJ et al. Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function. 1998 Biochem. J. pmid:9405284
Turner JS et al. Plasmin modulates the thrombin-evoked calcium response in C6 glioma cells. 1994 Biochem. J. pmid:8280096
Antonopoulou S et al. Identification of a new endogenous platelet-activating factor-like molecule in gingival crevicular fluid. 1998 Biochem. J. pmid:9480892
Takano H et al. Platelet aggregation induced by platelet-activating factor is suppressed by cystine protease inhibitor. 1991 Biochem. Med. Metab. Biol. pmid:2015107
Akiba S et al. Inhibitory effect of the leaf extract of Ginkgo biloba L. on oxidative stress-induced platelet aggregation. 1998 Biochem. Mol. Biol. Int. pmid:9891858
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Calcerrada MC et al. Glutamate release is involved in PAF-increased cyclic GMP levels in hippocampus. 1999 Biochem. Mol. Biol. Int. pmid:10204090
Suzuki H et al. Evidence for the production of platelet-activating factor by murine embryos and its putative role in the maternal physiology. 1995 Biochem. Mol. Biol. Int. pmid:8589634
Ventura MA et al. The adhesiveness of monocytic U937 cells is stimulated by pro-inflammatory agents and inhibited by adenosine 3':5'-cyclic monophosphate. 1990 Biochem. Pharmacol. pmid:2154991
Ko FN et al. Inhibition of collagen-induced platelet aggregation and adhesion by a pseudocyanide derivative of avicine isolated from Zanthoxylum integrifoliolum Merr. 1993 Biochem. Pharmacol. pmid:8216367
Yamada K et al. Parallel inhibition of platelet-activating factor-induced protein phosphorylation and serotonin release by K-252a, a new inhibitor of protein kinases, in rabbit platelets. 1988 Biochem. Pharmacol. pmid:3128296
Edwards MC et al. Secretion and properties of a polypeptide factor generated by phorbol ester stimulation of human blood platelets. 1987 Biochem. Pharmacol. pmid:3606649
Tanizawa H and Tai HH Synergism between chemotactic peptide and platelet-activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils. 1989 Biochem. Pharmacol. pmid:2547385
Daniels RH et al. Differential regulation of early phase and late phase responses in human neutrophils by cAMP. 1993 Biochem. Pharmacol. pmid:8387301
McNamara PJ et al. Autacoid binding to serum proteins. Interaction of platelet activating factor (PAF) with human serum alpha-1-acid glycoprotein (AAG). 1986 Biochem. Pharmacol. pmid:3947392
Dewald B and Baggiolini M Evaluation of PAF antagonists using human neutrophils in a microtiter plate assay. 1987 Biochem. Pharmacol. pmid:3649232
Sugatani J et al. Inhibition of rabbit platelet aggregation by nucleoside 5'-alkylphosphates: correlation with inhibition of agonist-induced calcium influx. 2000 Biochem. Pharmacol. pmid:10825464
Agarwal KC et al. Platelet-activating factor (PAF)-induced platelet aggregation. Modulation by plasma adenosine and methylxanthines. 1994 Biochem. Pharmacol. pmid:7986202
Shibata K et al. Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils. 1996 Biochem. Pharmacol. pmid:8678902
Pretolani M et al. From anti-asthma drugs to PAF-acether antagonism and back. Present status. 1989 Biochem. Pharmacol. pmid:2655601
Anderson R et al. Membrane stabilizing, anti-oxidative interactions of propranolol and dexpropranolol with neutrophils. 1996 Biochem. Pharmacol. pmid:8694859
Lohmeyer M et al. Stimulation of intracellular free calcium increases by platelet-activating factor in HT29 colon carcinoma cells. Spectrofluorimetric and preliminary spatio-temporal analysis using confocal laser scanning fluorescence imaging microscopy. 1994 Biochem. Pharmacol. pmid:8147917
O'Flaherty JT Phospholipid metabolism and stimulus-response coupling. 1987 Biochem. Pharmacol. pmid:3030324
Khandwala A et al. REV 2871 (CHBZ): a potent antiallergic agent with a novel mechanism of action. I. Activity profile as an inhibitor of mediator release. 1987 Biochem. Pharmacol. pmid:2435293