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Evidence for the autocrine induction of capacitation of mammalian spermatozoa. |
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Platelet-activating factor antagonism and streptokinase-induced hypotension in clinical acute myocardial infarction. |
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Platelet-activating factor antagonist, SM-12502, attenuates experimental glomerular thrombosis in rats. |
2001 |
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Platelet-activating factor-induced early activation of NF-kappa B plays a crucial role for organ clearance of Candida albicans. |
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Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver. |
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Platelet activating factor degradation in tear fluid from guinea pigs with allergic conjunctivitis. |
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Effect of polyunsaturated fatty acid (PUFA) supplementation on intestinal inflammation and necrotizing enterocolitis (NEC) in a neonatal rat model. |
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Effects of platelet-activating factor on cytokine production by human uterine cervical fibroblasts. |
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Mol. Hum. Reprod. |
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Could platelet activating factor play a role in developmental dyslexia? |
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Prostaglandins Leukot. Essent. Fatty Acids |
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Role of platelet-activating factor in hepatectomy with Pringle's maneuver. |
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Metabolic fate of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine by human spermatozoa: biosynthesis and biodegradation. |
2001 |
Life Sci. |
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Platelet-activating factor (PAF)-acetylhydrolase and PAF-like compounds in the lung: effects of hyperoxia. |
2001 |
Biochim. Biophys. Acta |
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Inhibition of human platelet aggregation by amides and ester of salicylic acid with platelet-activating factor analogs. |
2001 |
Biochemistry Mosc. |
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Effect of a specific cysteinyl leukotriene-receptor 1-antagonist (montelukast) on the transmigration of eosinophils across human umbilical vein endothelial cells. |
2001 |
Clin. Exp. Allergy |
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Platelet-activating factor and endotoxin activate CCAAT/enhancer binding protein in rat small intestine. |
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Platelet-activating factor content in boar spermatozoa correlates with fertility. |
2001 |
Theriogenology |
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Detection of platelet-activating factor in gingival tissue surrounding failed dental implants. |
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J. Periodontol. |
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Eotaxin promotes eosinophil transmigration via the activation of the plasminogen-plasmin system. |
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Role of the sarcoplasmic reticulum Ca2+-ATPase on heat production and thermogenesis. |
2001 |
Biosci. Rep. |
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Platelets cross-talk with tumor cells. |
2001 |
Haemostasis |
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Dissipative metabolic patterns respond during neutrophil transmembrane signaling. |
2001 |
Proc. Natl. Acad. Sci. U.S.A. |
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Impact of PAF antagonist BN 52021 (Ginkolide B) on post-ischemic graft function in clinical lung transplantation. |
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J. Heart Lung Transplant. |
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PAF increases vascular permeability without increasing pulmonary arterial pressure in the rat. |
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Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents. |
2001 |
Bioorg. Med. Chem. Lett. |
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Effects of a platelet-activating factor antagonist on lung injury and ventilation after cardiac operation. |
2001 |
Ann. Thorac. Surg. |
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Localization and distribution of platelet activating factor receptors in the mouse ovary and oviduct during the estrous cycle and early pregnancy. |
2001 |
Am. J. Reprod. Immunol. |
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Effects of inhibition of PAF, ICAM-1 and PECAM-1 on gut barrier failure caused by intestinal ischemia and reperfusion. |
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Scand. J. Gastroenterol. |
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Am. J. Physiol. Lung Cell Mol. Physiol. |
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PAF mediates cigarette smoke-induced goblet cell metaplasia in guinea pig airways. |
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Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia. |
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In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice. |
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Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis. |
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Decongestant efficacy of desloratadine in patients with seasonal allergic rhinitis. |
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Allergy |
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2001 |
Domest. Anim. Endocrinol. |
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Cytidine (5') diphosphocholine-induced decrease in cerebral platelet activating factor is due to inactivation of its synthesizing enzyme cholinephosphotransferase in aged rats. |
2001 |
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Platelet-associated and secreted PAF-acetylhydrolase activity in patients with stable angina: sequential changes of the enzyme activity after angioplasty. |
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Eur. J. Clin. Invest. |
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The mechanism of increased renal susceptibility to toxic substances in the elderly. Part I. The role of increased vasoconstriction. |
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Int Urol Nephrol |
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Hepatocyte growth factor is a regulator of monocyte-macrophage function. |
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Platelet activating factor does not improve intrauterine insemination outcome. |
2001 |
Am. J. Obstet. Gynecol. |
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The role of polyunsaturated fatty acid supplementation in intestinal inflammation and neonatal necrotizing enterocolitis. |
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Lipids |
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Ameliorating effects of fluorocarbon emulsion on sickle red blood cell-induced obstruction in an ex vivo vasculature. |
2001 |
Blood |
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Promotion of platelet aggregation by sera from brucellosis patients with antiphosphatidylcholine antibodies. |
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Platelet-activating factor evokes Ca2+ transients after the blockade of ryanodine receptor by dantrolene in RAW 264.7 macrophages. |
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Efficient assembly of the phomactin core via two different macrocyclization protocols. |
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Org. Lett. |
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Entry of gut lymph into the circulation primes rat neutrophil respiratory burst in hemorrhagic shock. |
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Crit. Care Med. |
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Involvement of platelet activation in experimental osteonecrosis in rabbits. |
2001 |
Int J Exp Pathol |
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Regulation of VEGF-induced endothelial cell PAF synthesis: role of p42/44 MAPK, p38 MAPK and PI3K pathways. |
2001 |
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Maturational changes in ovine pulmonary metabolism of platelet-activating factor: implications for postnatal adaptation. |
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Mol. Genet. Metab. |
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Modification of eosinophil function by suplatast tosilate (IPD), a novel anti-allergic drug. |
2001 |
Int. Immunopharmacol. |
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Lipoprotein-associated phospholipase A2: a potential new risk factor for coronary artery disease and a therapeutic target. |
2001 |
Curr Opin Pharmacol |
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Inhibition of store-operated Ca(2+) influx by acidic extracellular pH in cultured human microglia. |
2001 |
Glia |
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Hemofiltration reduces the serum priming activity on neutrophil chemiluminescence in septic patients. |
2001 |
Kidney Int. |
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PAF receptor antagonist modulates neutrophil responses with thermal injury in vivo. |
2001 |
Am. J. Physiol., Cell Physiol. |
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Effect of platelet-activating factor on gastrin release from cultured rabbit G-cells. |
2001 |
Dig. Dis. Sci. |
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Endothelial cell PAF synthesis following thrombin stimulation utilizes Ca(2+)-independent phospholipase A(2). |
2001 |
Biochemistry |
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Platelet activation and platelet-erythrocyte aggregates in end-stage renal disease patients on hemodialysis. |
2001 |
Thromb. Haemost. |
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Single nucleotide polymorphism of human platelet-activating factor receptor impairs G-protein activation. |
2001 |
J. Biol. Chem. |
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Double blind, randomised, placebo controlled study of a platelet activating factor antagonist, lexipafant, in the treatment and prevention of organ failure in predicted severe acute pancreatitis. |
2001 |
Gut |
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Intraleucocyte platelet-activating factor levels in desmopressin-treated patients with haemophilia A and von Willebrand disease. |
2001 |
Haemophilia |
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Role of gut flora on intestinal group II phospholipase A2 activity and intestinal injury in shock. |
2001 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Exogenous platelet-activating factor stimulates cell proliferation in mouse pre-implantation embryos prior to the fourth cell cycle and shows isoform-specific stimulatory effects. |
2001 |
Zygote |
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Vitamin E attenuates the injurious effects of bioactive phospholipids on human ciliated epithelium in vitro. |
2001 |
Eur. Respir. J. |
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Decoupling of intracellular calcium signaling in granulocytes after exhaustive exercise. |
2001 |
Int J Sports Med |
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Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E2. |
2001 |
Pflugers Arch. |
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Platelet-endothelial interactions in atherosclerosis. |
2001 |
Curr Atheroscler Rep |
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Inhibition of platelet-activating factor receptor binding by aporphine and phenanthrenoid alkaloids from Aromadendron elegans. |
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Planta Med. |
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Synthesis and biological activity of amide derivatives of ginkgolide A. |
2001 |
J Asian Nat Prod Res |
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Reactive oxygen species mediate angiotensin II-induced leukocyte-endothelial cell interactions in vivo. |
2001 |
J. Leukoc. Biol. |
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Multidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factor. |
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Biochem. J. |
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Local anesthetic effects on priming and activation of human neutrophils. |
2001 |
Anesthesiology |
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Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis. |
2001 |
J. Surg. Res. |
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Roles for platelet-activating factor and *NO-derived oxidants causing neutrophil adherence after CO poisoning. |
2001 |
Am. J. Physiol. Heart Circ. Physiol. |
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Similar effects of ether phospholipids, PAF and lyso-PAF on the Ca(2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes. |
2001 |
Int. Immunopharmacol. |
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Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids. |
2001 |
J. Lipid Res. |
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Role of petasin in the potential anti-inflammatory activity of a plant extract of petasites hybridus. |
2001 |
Biochem. Pharmacol. |
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Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat. |
2001 |
J. Neurovirol. |
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Interleukin-2 activates human peripheral blood eosinophils. |
2001 |
Cell. Immunol. |
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Novel azo derivatives as prodrugs of 5-aminosalicylic acid and amino derivatives with potent platelet activating factor antagonist activity. |
2001 |
J. Med. Chem. |
pmid:11520209
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Cardiovascular properties of yangambin, a lignan isolated from Brazilian plants. |
2001 |
Cardiovasc Drug Rev |
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BMS-229724 is a tight-binding inhibitor of cytosolic phospholipase A2 that acts at the lipid/water interface and possesses anti-inflammatory activity in skin inflammation models. |
2001 |
J. Pharmacol. Exp. Ther. |
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Corneal stimulation of MMP-1, -9 and uPA by platelet-activating factor is mediated by cyclooxygenase-2 metabolites. |
2001 |
Curr. Eye Res. |
pmid:11840344
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Importance of microcirculatory disturbances in the pathogenesis of pancreatitis. |
2001 |
Zentralbl Chir |
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Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine. |
2001 |
Exp. Mol. Med. |
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Selenium modulates 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) biosynthesis in bovine aortic endothelial cells. |
2001 |
Antioxid. Redox Signal. |
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Biogenesis of G-protein mediated calcium signaling in human megakaryocytes. |
2001 |
Thromb. Haemost. |
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Neutrophil apoptosis is delayed by trauma patients' plasma via a mechanism involving proinflammatory phospholipids and protein kinase C. |
2001 |
Surg Infect (Larchmt) |
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Effect of platelet activating factor and butyrate on the expression of interleukin-2 receptor alpha in nasopharyngeal carcinoma cells. |
2001 |
Int. J. Oncol. |
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Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways. |
2001 |
Br. J. Pharmacol. |
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Experimental and emerging therapies for sepsis and septic shock. |
2001 |
Expert Opin Investig Drugs |
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Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme. |
2001 |
Biochemistry |
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RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses. |
2001 |
Biochemistry |
pmid:11297424
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The impact of platelet-activating factor (PAF)-like mediators on the functional activity of neutrophils: anti-inflammatory effects of human PAF-acetylhydrolase. |
2001 |
Clin. Exp. Immunol. |
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Intravenous immunoglobulin preparations induce mild activation of neutrophils in vivo via triggering of macrophages--studies in a rat model. |
2001 |
Br. J. Haematol. |
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Differential interaction of platelet-activating factor and NMDA receptor function in hippocampal and dorsal striatal memory processes. |
2001 |
Neurobiol Learn Mem |
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Aiboshi J et al. |
Blood transfusion and the two-insult model of post-injury multiple organ failure. |
2001 |
Shock |
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Procoagulant activity on platelets adhered to collagen or plasma clot. |
2001 |
Arterioscler. Thromb. Vasc. Biol. |
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Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells. |
2001 |
FASEB J. |
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