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Ketotifen inhibits paf-acether biosynthesis and beta-hexosaminidase release in mouse mast cells stimulated with antigen. |
1987 |
Eur. J. Pharmacol. |
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Human neutrophil platelet-activating factor: molecular heterogeneity in unstimulated and ionophore-stimulated cells. |
1987 |
Biochim. Biophys. Acta |
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Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep. |
1987 |
J. Pharmacol. Exp. Ther. |
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Interactions of the alkyl-ether-phospholipid, platelet activating factor (PAF) with platelets, neural cells, and the psychotropic drugs triazolobenzodiazepines. |
1987 |
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[Synthesis of 1-(1-alkenyl)-2-acetyl-sn-glycero-3-phosphocholines, the aldehyded analogs of platelet activating factor]. |
1987 |
Bioorg. Khim. |
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Heterogeneity of vascular smooth muscle responsiveness to lipid vasoactive mediators. |
1987 |
Blood Vessels |
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Potent inhibition of PAF-stimulated human platelets and polymorphonuclear leukocytes by the PGE1 analog OP-1206. |
1987 |
Prog. Clin. Biol. Res. |
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Interference of the PAF-acether antagonist BN 52021 with anaphylaxis in the guinea pig. |
1987 |
Adv. Prostaglandin Thromboxane Leukot. Res. |
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Metabolism of platelet-activating factor (alkylacetylphosphocholine) by type-II epithelial cells and fibroblasts from rat lungs. |
1987 |
Biochim. Biophys. Acta |
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Preferential human eosinophil chemotactic activity of the platelet-activating factor (PAF) 1-0-hexadecyl-2-acetyl-sn-glyceryl-3-phosphocholine (AGEPC). |
1987 |
J. Clin. Immunol. |
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Structure-activity relationship in PAF-acether. 3. Hydrophobic contribution to agonistic activity. |
1987 |
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Effect of BN 52021, a specific antagonist of platelet activating factor (PAF-acether), on calcium movements and phosphatidic acid production induced by PAF-acether in human platelets. |
1987 |
Thromb. Res. |
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Metabolism of 1-alkyl-2-acyl-GPC in human platelets in response to stimulation by thrombin. |
1987 |
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Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat. |
1987 |
Agents Actions |
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Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways. |
1987 |
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Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage. |
1987 |
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Atropine is an inhibitor of the chemiluminescence induced by platelet-activating factor in human neutrophils. |
1987 |
Acta Biochim. Biophys. Hung. |
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1987 |
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[Effects of SIN-1, a metabolite of molsidomine, on paf-acether-blood platelets interactions]. |
1987 |
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The final step in the de novo biosynthesis of platelet-activating factor. Properties of a unique CDP-choline:1-alkyl-2-acetyl-sn-glycerol choline-phosphotransferase in microsomes from the renal inner medulla of rats. |
1987 |
J. Biol. Chem. |
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Platelet-activating factor mediates hemodynamic changes and lung injury in endotoxin-treated rats. |
1987 |
J. Clin. Invest. |
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Platelet-activating factor antagonists. |
1987 |
Annu. Rev. Pharmacol. Toxicol. |
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Human plasma platelet-activating factor acetylhydrolase. Purification and properties. |
1987 |
J. Biol. Chem. |
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Mechanistic studies of early pregnancy associated thrombocytopenia (EPAT) in the mouse. |
1987 |
Am J Reprod Immunol Microbiol |
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Occurrence of an endogenous inhibitor of platelet-activating factor in rat liver. |
1987 |
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Transacylation of lyso platelet-activating factor and other lysophospholipids by macrophage microsomes. Distinct donor and acceptor selectivities. |
1987 |
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Platelet-activating factor: mediator of the third pathway of platelet aggregation? A study in three patients with deficient platelet-activating factor synthesis. |
1987 |
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Platelet-activating factor-acether-induced relaxation of guinea pig airway muscle: role of prostaglandin E2 and the epithelium. |
1987 |
J. Pharmacol. Exp. Ther. |
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Cooperativity between platelet-activating factor and collagen in platelet aggregation. |
1987 |
Biochem. Biophys. Res. Commun. |
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Mobilization of hepatic calcium pools by platelet activating factor. |
1987 |
Biochemistry |
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Synthesis and biological activity of fluorine-modified platelet activating factors. |
1987 |
Chem. Pharm. Bull. |
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Use of a bioassay for embryo-derived platelet-activating factor as a means of assessing quality and pregnancy potential of human embryos. |
1987 |
Fertil. Steril. |
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Inhibition of rat endotoxin-induced lethality by BN 52021 and BN 52063, compounds with PAF-acether antagonistic effect and protease-inhibitory activity. |
1987 |
Int J Tissue React |
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Effects of PAF-acether on electrophysiological response of isolated retina. |
1987 |
Int J Tissue React |
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Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis. |
1987 |
Immunopharmacology |
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Biological properties of the antagonist SRI 63-441 in the PAF and endotoxin models of hypotension in the rat and dog. |
1987 |
Immunopharmacology |
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Fatty acid composition of diacyl, alkylacyl, and alkenylacyl phospholipids of control and arachidonate-depleted rat polymorphonuclear leukocytes. |
1987 |
J. Lipid Res. |
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Pharmacological evidence for a role of lipoxygenase products in platelet-activating factor (PAF)-induced hyperalgesia. |
1987 |
Biochem. Pharmacol. |
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Pharmacological actions of WEB 2086, a new specific antagonist of platelet activating factor. |
1987 |
J. Pharmacol. Exp. Ther. |
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Inhibition of human lymphocyte proliferation and interleukin 2 production by platelet activating factor (PAF-acether): reversal by a specific antagonist, BN 52021. |
1987 |
Biochem. Biophys. Res. Commun. |
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The degradation of platelet-activating factor and related lipids: susceptibility to phospholipases C and D. |
1987 |
Lipids |
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Platelet-leukocyte interaction: activation of rabbit platelets by FMLP-stimulated neutrophils. |
1987 |
Br. J. Pharmacol. |
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Antitumor activity of synthetic alkylphospholipids with or without PAF activity. |
1987 |
Lipids |
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Effect of synthetic phospholipids on platelet aggregation and serotonin release. |
1987 |
Lipids |
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Cytotoxic effects of ether lipids and derivatives in human nonneoplastic bone marrow cells and leukemic cells in vitro. |
1987 |
Lipids |
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Regulation of PAF-acether (platelet-activating factor) biosynthesis in cultured human vascular endothelial cells stimulated with thrombin. |
1987 |
Biochim. Biophys. Acta |
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Platelet-activating factor stimulates metabolism of phosphoinositides via phospholipase A2 in primary cultured rat hepatocytes. |
1987 |
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[Platelet activating factor]. |
1987 |
Nippon Rinsho |
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Platelet-activating factor effects on bovine pulmonary artery endothelial cells. |
1987 |
Circ. Res. |
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Species-specific variations in the molecular heterogeneity of the platelet-activating factor. |
1987 |
J. Immunol. |
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[IgE and anaphylaxis mediators]. |
1987 |
Allerg Immunol (Paris) |
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Can the synthesis of platelet-activating factor, a potent vasodilator and pro-aggregatory agent, be altered by dietary marine oils? |
1987 |
Clin. Exp. Pharmacol. Physiol. |
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Barnes PJ |
The changing face of asthma. |
1987 |
Q. J. Med. |
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Airway responses to platelet-activating factor. |
1987 |
Am. Rev. Respir. Dis. |
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Prolongation of pig-to-dog renal xenograft survival by modification of the inflammatory mediator response. |
1987 |
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Platelet activating factor; chemical and biochemical characteristics. |
1987 |
Prog. Lipid Res. |
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Effect of platelet-activating factor (PAF-acether) and its specific receptor antagonist, BN 52021, on interleukin 1 (IL1) release and synthesis by rat spleen adherent monocytes. |
1987 |
Prostaglandins |
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Braquet P and Rola-Pleszczynski M |
The role of PAF in immunological responses: a review. |
1987 |
Prostaglandins |
pmid:3313527
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Anti-anaphylactic properties of BN 52021: a potent platelet activating factor antagonist. |
1987 |
Adv. Exp. Med. Biol. |
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New concepts in the pathogenesis of bronchial hyperresponsiveness. |
1987 |
Agents Actions Suppl. |
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Platelet activation--an overview. |
1987 |
Agents Actions Suppl. |
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Platelet activating factor-mediated leukotriene biosynthesis in rat lungs: effect of prostaglandins E1 and F1 alpha. |
1987 |
Biochem. Biophys. Res. Commun. |
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Arachidonate metabolites, platelet-activating factor, and the mobilization of protein kinase C in human polymorphonuclear neutrophils. |
1987 |
J. Immunol. |
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Phospholipid metabolism and stimulus-response coupling. |
1987 |
Biochem. Pharmacol. |
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Measurement of platelet-activating factor by physicochemical technique s. |
1987 |
Am. Rev. Respir. Dis. |
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Perspectives in platelet-activating factor research. |
1987 |
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[Platelet aggregation tests in 26 cases of heparin-induced thrombopenia. Methodological, diagnostic problems and therapeutic aspects]. |
1987 |
J Mal Vasc |
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Relationship between platelet aggregating factor and von Willebrand factor in thrombotic thrombocytopenic purpura. |
1987 |
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Asymmetric synthesis of (+)- and (-)-batyl alcohol, a key synthetic intermediate for platelet-activating factor, by using biocatalysts. |
1987 |
Chem. Pharm. Bull. |
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Diketopiperazine derivatives, a new series of platelet-activating factor inhibitors. |
1987 |
Chem. Pharm. Bull. |
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Attenuation of endotoxin-induced increase in glucose metabolism by platelet-activating factor antagonist. |
1987 |
Circ. Shock |
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BN 52021 displaces [3H]paf-acether from, and inhibits its binding to intact human platelets. |
1987 |
Eur. J. Pharmacol. |
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G-protein dissociation, GTP-GDP exchange and GTPase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe. |
1987 |
Biochem. Biophys. Res. Commun. |
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Platelet activating factor (PAF) is a potent stimulator of porcine tracheal fluid secretion in vitro. |
1987 |
Eur. J. Pharmacol. |
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Antibody to platelet activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine; PAF). |
1987 |
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PAF-acether induced cardiac dysfunction in the isolated perfused guinea pig heart. |
1987 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process. |
1987 |
J. Biol. Chem. |
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PAF binding sites. Characterization by [3H]52770 RP, a pyrrolo[1,2-c]thiazole derivative, in rabbit platelets. |
1987 |
Biochem. Pharmacol. |
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Dale MM and Penfield A |
Comparison of the effects of indomethacin, RHC80267 and R59022 on superoxide production by 1,oleoyl-2,acetyl glycerol and A23187 in human neutrophils. |
1987 |
Br. J. Pharmacol. |
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A platelet-activating factor receptor antagonist protects against renal function deterioration in nephrotoxic nephritis. |
1987 |
Adv. Prostaglandin Thromboxane Leukot. Res. |
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Effect of the PAF-antagonist SRI 63-441 on the allergic reaction in awake dogs with natural asthma. |
1987 |
Agents Actions Suppl. |
pmid:2823582
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O'Flaherty JT and Wykle RL |
Metabolic origin and fate of platelet-activating factor. |
1987 |
Agents Actions Suppl. |
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Carotid endarterectomy in patients with heparin-induced platelet activation: comparative efficacy of aspirin and iloprost (ZK36374). |
1987 |
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The diacylglycerol kinase inhibitor R59022 potentiates superoxide production but not secretion induced by fMet-Leu-Phe: effects of leupeptin and the protein kinase C inhibitor H-7. |
1987 |
Biochem. Biophys. Res. Commun. |
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Serafin WE and Austen KF |
Mediators of immediate hypersensitivity reactions. |
1987 |
N. Engl. J. Med. |
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Evidence for the receptor-operated calcium channels in human platelet plasma membrane. |
1987 |
Thromb. Res. |
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Platelet activating factor (PAF) as a mediator of injury in nephrotoxic nephritis. |
1987 |
Kidney Int. |
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Morley J and Sanjar S |
PAF, ketotifen and asthma. |
1987 |
N. Z. Med. J. |
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Control of the proliferation and differentiation of GEJ under platelet aggregating factor treatment. |
1987 |
Acta Endocrinol Suppl (Copenh) |
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Shalit M et al. |
Platelet-activating factor both stimulates and "primes" human polymorphonuclear leukocyte actin filament assembly. |
1987 |
Blood |
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Krishnamurthi S et al. |
Effect of phorbol 12-myristate 13-acetate (PMA) on agonist-induced arachidonate release and 5-hydroxytryptamine secretion in human platelets. Dependence of effects on agonist type and time of incubation with PMA. |
1987 |
Biochim. Biophys. Acta |
pmid:3101746
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Reversal of central nervous system involvement in hemolytic uremic syndrome by use of plasma exchanges. |
1987 |
Clin Pediatr (Phila) |
pmid:3119270
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Doebber TW and Wu MS |
Platelet-activating factor (PAF) stimulates the PAF-synthesizing enzyme acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O2-acetyltransferase and PAF synthesis in neutrophils. |
1987 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:3478712
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PAF, platelets and asthma. Proceedings of a meeting. September 7-9, 1986. |
1987 |
Agents Actions Suppl. |
pmid:3478993
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Sage SO and Rink TJ |
The kinetics of changes in intracellular calcium concentration in fura-2-loaded human platelets. |
1987 |
J. Biol. Chem. |
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Farr RS et al. |
Platelet abnormalities in asthma--do they exist in humans? |
1987 |
Agents Actions Suppl. |
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Tumor necrosis factor/cachectin stimulates peritoneal macrophages, polymorphonuclear neutrophils, and vascular endothelial cells to synthesize and release platelet-activating factor. |
1987 |
J. Exp. Med. |
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Lack of PAF release in extrinsic asthma. |
1987 |
Agents Actions Suppl. |
pmid:3478995
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Pharmacologic modulation of PAF-induced mortality in mice. |
1987 |
Agents Actions |
pmid:3120513
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Bussolino F et al. |
Studies on the mechanism of interleukin 1 stimulation of platelet activating factor synthesis in human endothelial cells in culture. |
1987 |
Biochim. Biophys. Acta |
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