Platelet activating factor

Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Platelet activating factor, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Platelet activating factor?

Platelet activating factor is suspected in Ischemia, Pleurisy, Atherosclerosis, Inflammatory disorder, Retinal Diseases, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Platelet activating factor

MeSH term MeSH ID Detail
Viremia D014766 4 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Brain Hemorrhage, Traumatic D020201 1 associated lipids
Bronchiectasis D001987 7 associated lipids
Anthrax D000881 1 associated lipids
Heart Injuries D006335 6 associated lipids
Arenaviridae Infections D001117 1 associated lipids
Neurologic Manifestations D009461 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Platelet activating factor

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Platelet activating factor?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Platelet activating factor?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Platelet activating factor?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Platelet activating factor?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Platelet activating factor?

Knock-out

Knock-out are used in the study 'A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.' (Leary PJ et al., 2008).

Mouse Model

Mouse Model are used in the study 'A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.' (Cheng L et al., 2009).

Transgenic Model

Transgenic Model are used in the study 'Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons.' (Ryan SD et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Platelet activating factor

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Authors Title Published Journal PubMed Link
Carretta MD et al. Butyric acid stimulates bovine neutrophil functions and potentiates the effect of platelet activating factor. 2016 Vet. Immunol. Immunopathol. pmid:27288853
Liu R et al. Pyruvate in oral rehydration salt improves hemodynamics, vasopermeability and survival after burns in dogs. 2016 Burns pmid:27130433
Grambow E et al. Differential effects of endogenous, phyto and synthetic cannabinoids on thrombogenesis and platelet activity. 2016 Biofactors pmid:27151562
Eleftheriou K et al. Comparative Experimental and Computational Study of Monoalkyl Chain Phosphatidylcholine-Containing Thermoresponsive Liposomes. 2016 J Phys Chem B pmid:27280363
Kamaladasa A et al. Lipopolysaccharide acts synergistically with the dengue virus to induce monocyte production of platelet activating factor and other inflammatory mediators. 2016 Antiviral Res. pmid:27476044
Schauberger E et al. Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets. 2016 Curr Allergy Asthma Rep pmid:27333777
Wang JM and Chen J Damage of vascular endothelial barrier induced by explosive blast and its clinical significance. 2016 Chin. J. Traumatol. pmid:27321288
Nel JG et al. Pneumolysin Mediates Platelet Activation In Vitro. 2016 Lung pmid:27192991
Silva-Herdade AS et al. Erythrocyte deformability - A partner of the inflammatory response. 2016 Microvasc. Res. pmid:27142964
Wright NR et al. Purulent Pericarditis and Abscessed Myocardium with Acute Myocardial Infarction. 2016 Am. J. Med. pmid:26524710