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PMS-1077, a PAF antagonist, induced differentiation of HL-60 cells with its novel activity. |
2010 |
Cell Biol. Int. |
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Prolonged hypoxia modulates platelet activating factor receptor-mediated responses by fetal ovine pulmonary vascular smooth muscle cells. |
2010 |
Mol. Genet. Metab. |
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Efficacy and tolerability of rupatadine at four times the recommended dose against histamine- and platelet-activating factor-induced flare responses and ex vivo platelet aggregation in healthy males. |
2010 |
Br. J. Dermatol. |
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Phosphoinositide 3-kinase gamma mediates chemotactic responses of human eosinophils to platelet-activating factor. |
2010 |
Int. Immunopharmacol. |
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[Expression and regulation of pituitary adenylate cyclase-activating polypeptide mRNA in pregnant rat corpus luteum]. |
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Effects of the new benzimidazole derivative TAS-203, an orally active phosphodiesterase 4 inhibitor, on airway inflammation in rats and emetic responses in ferrets. |
2010 |
Arzneimittelforschung |
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Kordan W et al. |
Effect of platelet activating factor (PAF) supplementation in semen extender on viability and ATP content of cryopreserved canine spermatozoa. |
2010 |
Pol J Vet Sci |
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Identification of VEGF receptor-2 tyrosine phosphorylation sites involved in VEGF-mediated endothelial platelet-activating factor synthesis. |
2010 |
Can. J. Physiol. Pharmacol. |
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Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. |
2010 |
PLoS ONE |
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[The levels of platelet-activating factor and nitric oxide synthase in bronchial asthma at high altitude]. |
2010 |
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[Inhibitory effect of TBN on platelet aggregation in rabbit]. |
2010 |
Zhong Yao Cai |
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Effects of ropivacaine on adhesion molecule CD11b expression and function in human neutrophils. |
2010 |
Int. Immunopharmacol. |
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PAF exerts a direct apoptotic effect on the rat H9c2 cardiomyocytes in Ca2+-dependent manner. |
2010 |
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Platelet-activating factor involvement in thioacetamide-induced experimental liver fibrosis and cirrhosis. |
2010 |
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Toll-like receptor ligands induce polymorphonuclear leukocyte migration: key roles for leukotriene B4 and platelet-activating factor. |
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Bepotastine besilate, a highly selective histamine H(1) receptor antagonist, suppresses vascular hyperpermeability and eosinophil recruitment in in vitro and in vivo experimental allergic conjunctivitis models. |
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Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation. |
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[Induction effect of platelet-activating factor on Src-suppressed C kinase substrate gene expression in rat pulmonary microvascular endothelial cells]. |
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The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. |
2010 |
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2010 |
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Activation of human mast cells through the platelet-activating factor receptor. |
2010 |
J. Allergy Clin. Immunol. |
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Lipoxygenase metabolites modulate vascular-derived platelet activating factor production following endotoxin challenge. |
2010 |
Vet. Immunol. Immunopathol. |
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H2O2 and PAF mediate Abeta1-42-induced Ca2+ dyshomeostasis that is blocked by EGb761. |
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The first diastereoselective synthesis of cinerins A-C, PAF-antagonistic macrophyllin-type bicyclo[3.2.1]octane neolignans, using a novel Pd-catalysed oxyarylation. |
2010 |
Org. Biomol. Chem. |
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Novel targets and regulatory ordeal by QT interval. |
2010 |
Br J Clin Pharmacol |
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No cardiac effects of therapeutic and supratherapeutic doses of rupatadine: results from a 'thorough QT/QTc study' performed according to ICH guidelines. |
2010 |
Br J Clin Pharmacol |
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Persistency and pathway of isoflurane-induced inhibition of superoxide production by neutrophils. |
2010 |
Can J Anaesth |
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Platelet-activating factor levels of serum and gingival crevicular fluid in nonsmoking patients with periodontitis and/or coronary heart disease. |
2010 |
Clin Oral Investig |
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Role of platelet-activating factor in cell death signaling in the cornea: A review. |
2010 |
Mol. Neurobiol. |
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The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function. |
2010 |
Platelets |
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Platelet-activating factor and acute myelogenous leukemia. |
2010 |
Exp. Hematol. |
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Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis. |
2010 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Alpha2-adrenergic receptors and their core involvement in the process of axonal growth in retinal explants. |
2010 |
Invest. Ophthalmol. Vis. Sci. |
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Phosphorylation of lysophosphatidylcholine acyltransferase 2 at Ser34 enhances platelet-activating factor production in endotoxin-stimulated macrophages. |
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Endothelial progenitor cells express PAF receptor and respond to PAF via Ca(2+)-dependent signaling. |
2010 |
Biochim. Biophys. Acta |
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Role for basophils in systemic anaphylaxis. |
2010 |
Chem Immunol Allergy |
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In vitro diagnosis of anaphylaxis. |
2010 |
Chem Immunol Allergy |
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Endothelial cell prostaglandin I(2) and platelet-activating factor production are markedly attenuated in the calcium-independent phospholipase A(2)beta knockout mouse. |
2010 |
Biochemistry |
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Immune factors in human embryo culture and their significance. |
2010 |
Medicina (Kaunas) |
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Sphingosine-1-phosphate modulation of basal permeability and acute inflammatory responses in rat venular microvessels. |
2010 |
Cardiovasc. Res. |
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Protection of carbon monoxide intraperitoneal administration from rat intestine injury induced by lipopolysaccharide. |
2010 |
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Vascular barrier regulation by PAF, ceramide, caveolae, and NO - an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature. |
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Cell. Physiol. Biochem. |
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Three new compounds from Morus nigra L. |
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J Asian Nat Prod Res |
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Rapamycin inhibits VEGF-induced microvascular hyperpermeability in vivo. |
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Microcirculation |
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Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor. |
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J. Immunol. |
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Glycosylphosphatidylinositol anchor analogues sequester cholesterol and reduce prion formation. |
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Platelet-activating factor receptor mediates oxidized low density lipoprotein-induced migration of bone marrow-derived mesenchymal stem cells. |
2010 |
Cell. Physiol. Biochem. |
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Exogenous platelet-activating factor improves the motility of human spermatozoa evaluated with C.A.S.A.: optimal concentration and incubation time. |
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The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans. |
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[Discovery and characterization of novel lysophospholipid acyltransferases]. |
2010 |
Seikagaku |
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Platelet-activating factor interaction with the human erythrocyte membrane. |
2009 Sep-Oct |
J. Biochem. Mol. Toxicol. |
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Effects of Ginkgo biloba on airway histology in a mouse model of chronic asthma. |
2009 Mar-Apr |
Allergy Asthma Proc |
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Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity. |
2009 |
Pancreas |
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PMS777, a new cholinesterase inhibitor with anti-platelet activated factor activity, regulates amyloid precursor protein processing in vitro. |
2009 |
Neurochem. Res. |
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Posaconazole attenuates leukotriene B4 release and uptake of calcium by chemoattractant-activated human neutrophils: a potential strategy to control neutrophil-mediated inflammation. |
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Physalin B inhibits Rhodnius prolixus hemocyte phagocytosis and microaggregation by the activation of endogenous PAF-acetyl hydrolase activities. |
2009 |
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Ultraviolet B radiation generated platelet-activating factor receptor agonist formation involves EGF-R-mediated reactive oxygen species. |
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[New development of lysophospholipid acyltransferases]. |
2009 |
Tanpakushitsu Kakusan Koso |
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Expression and DNA microarray analysis of a platelet activating factor-related molecule in severe pneumonia in mice due to influenza virus and bacterial co-infection. |
2009 |
Jpn. J. Infect. Dis. |
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Streamlining the design of promising clinical trials: in-vitro testing of antithrombotic regimens and multiple agonists of platelet activation. |
2009 |
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Protection of PMS777, a new AChE inhibitor with PAF antagonism, against amyloid-beta-induced neuronal apoptosis and neuroinflammation. |
2009 |
Cell. Mol. Neurobiol. |
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Torsade de pointes associated with rupatadine. |
2009 |
Rev Esp Cardiol |
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Independent regulation of periarteriolar and perivenular nitric oxide mechanisms in the in vivo hamster cheek pouch microvasculature. |
2009 |
Microcirculation |
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2009 |
Lab. Invest. |
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2009 |
Mol. Pharmacol. |
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A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice. |
2009 |
Am. J. Physiol. Endocrinol. Metab. |
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Is platelet activity important in acute intracerebral hemorrhage? |
2009 |
Neurocrit Care |
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Treatment of sperm with platelet-activating factor does not improve intrauterine insemination outcome in unselected cases of mild male factor infertility: a prospective double-blind randomized crossover study. |
2009 |
Urology |
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[Signal pathways of eryptosis-review]. |
2009 |
Zhongguo Shi Yan Xue Ye Xue Za Zhi |
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[Influence of intensive insulin therapy on the intestinal microcirculatory dysfunction in rats with sepsis]. |
2009 |
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue |
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Inhibition of calcium-independent phospholipase A2 prevents inflammatory mediator production in pulmonary microvascular endothelium. |
2009 |
Respir Physiol Neurobiol |
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Simultaneous determination of rupatadine and its metabolite desloratadine in human plasma by a sensitive LC-MS/MS method: application to the pharmacokinetic study in healthy Chinese volunteers. |
2009 |
J Pharm Biomed Anal |
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New 1H-pyrazole-4-carboxamides with antiplatelet activity. |
2009 |
Arch. Pharm. (Weinheim) |
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Platelet activating factor (PAF) and activity of its biosynthetic and catabolic enzymes in blood and leukocytes of male patients with newly diagnosed heart failure. |
2009 |
Clin. Biochem. |
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Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis. |
2009 |
Biochim. Biophys. Acta |
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Peanuts can contribute to anaphylactic shock by activating complement. |
2009 |
J. Allergy Clin. Immunol. |
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Mast cells: makers and breakers of allergic inflammation. |
2009 |
Curr Opin Allergy Clin Immunol |
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Activation of a chloride channel by a trophic ligand is required for development of the mouse preimplantation embryo in vitro. |
2009 |
Biol. Reprod. |
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Blood-brain barrier breakdown by PAF and protection by XQ-1H due to antagonism of PAF effects. |
2009 |
Eur. J. Pharmacol. |
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Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases. |
2009 |
Inflamm Allergy Drug Targets |
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Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice. |
2009 |
J. Clin. Invest. |
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Platelet-activating factor-stimulated production of reactive oxygen species in ovarian granulosa cells from periovulatory follicles. |
2009 |
Cytometry A |
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Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders. |
2009 |
J. Neuroimmunol. |
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Macrophyllin-type bicyclo[3.2.1]octanoid neolignans from the leaves of Pleurothyrium cinereum. |
2009 |
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PAF-antagonistic bicyclo[3.2.1]octanoid neolignans from leaves of Ocotea macrophylla Kunth. (Lauraceae). |
2009 |
Phytochemistry |
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Effect of platelet-activating factor on motility, plasmalemma integrity, the process of capacitation and acrosome reaction of fresh and cryopreserved boar spermatozoa. |
2009 |
Pol J Vet Sci |
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Caveolae facilitate but are not essential for platelet-activating factor-mediated calcium mobilization and extracellular signal-regulated kinase activation. |
2009 |
J. Immunol. |
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The novel role of platelet-activating factor in protecting mice against lipopolysaccharide-induced endotoxic shock. |
2009 |
PLoS ONE |
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Pathophysiology of burns. |
2009 |
Wien Med Wochenschr |
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Respiratory burst function of ovine neutrophils. |
2009 |
BMC Immunol. |
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Post-ischaemic activation of kinases in the pre-conditioning-like cardioprotective effect of the platelet-activating factor. |
2009 |
Acta Physiol (Oxf) |
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Stimulation of Leishmania tropica protein kinase CK2 activities by platelet-activating factor (PAF). |
2009 |
Acta Trop. |
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HCl-activated neural and epithelial vanilloid receptors (TRPV1) in cat esophageal mucosa. |
2009 |
Am. J. Physiol. Gastrointest. Liver Physiol. |
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Treatment of acquired cold urticaria with rupatadine. |
2009 |
Allergy |
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A novel role for leucocytes in determining the severity of acute pancreatitis. |
2009 |
Gut |
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Inhibitors of TRP channels reveal stimulus-dependent differential activation of Ca2+ influx pathways in human neutrophil granulocytes. |
2009 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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Functional analysis of platelet-activating factor in the retinal pigment epithelial cells and choroidal endothelial cells. |
2009 |
Curr. Eye Res. |
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The effect of oxygen and light on the structure and function of the neonatal rat retina. |
2009 |
Doc Ophthalmol |
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Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. |
2009 |
Pancreas |
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