Platelet activating factor

Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Platelet activating factor, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Platelet activating factor?

Platelet activating factor is suspected in Ischemia, Pleurisy, Atherosclerosis, Inflammatory disorder, Retinal Diseases, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Platelet activating factor

MeSH term MeSH ID Detail
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Brain Injuries D001930 4 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteonecrosis D010020 5 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Platelet activating factor

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Platelet activating factor?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Platelet activating factor?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Platelet activating factor?

Related references are published most in these journals:

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What genes are associated with Platelet activating factor?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Platelet activating factor?

Knock-out

Knock-out are used in the study 'A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.' (Leary PJ et al., 2008).

Mouse Model

Mouse Model are used in the study 'A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice.' (Cheng L et al., 2009).

Transgenic Model

Transgenic Model are used in the study 'Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons.' (Ryan SD et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Platelet activating factor

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Per page 10 20 50 100 | Total 8526
Authors Title Published Journal PubMed Link
Liu BJ et al. [Effect of BN52021 on platelet activating factor induced aggregation of psoriatic polymorphonuclear neutrophils]. 1994 Zhonghua Yi Xue Za Zhi pmid:7994650
Ma X et al. [Corneal epithelial wound healing is delayed by platelet activating factor treatment]. 2004 Zhonghua Yan Ke Za Zhi pmid:15307983
Qin X et al. [The effect of platelet-activating factor antagonists on early bacteria translocation of rat after burn injury]. 1995 Zhonghua Wai Ke Za Zhi pmid:7587673
Ji Z et al. [The role of platelet activating factor in pathogenesis of acute pancreatitis in dogs]. 1997 Zhonghua Wai Ke Za Zhi pmid:10374489
Xiao J et al. [Effects of platelet activating factor and platelet activating factor receptor antagonist on spinal cord blood flow after spinal cord injury]. 1995 Zhonghua Wai Ke Za Zhi pmid:8762548
Yu P et al. [The roles of platelet activating factor in intestinal mucosal barrier injury after burn]. 1995 Zhonghua Wai Ke Za Zhi pmid:8565724
Han E et al. [Effect of chronic antiplatelet treatment on platelet activating factor-induced platelet activity in stroke]. 1991 Zhonghua Shen Jing Jing Shen Ke Za Zhi pmid:1868762
Wang ZY [Advances in the physiopathology of platelets]. 1984 Zhonghua Nei Ke Za Zhi pmid:6099795
Shi H et al. [Effects of a platelet-activating factor antagonist ONO-6240 on antigen induced eosinophil infiltration into the airways]. 1995 Zhonghua Nei Ke Za Zhi pmid:8731847
Ren G and Ye R [Changes in urinary excretion of platelet activating factor and its significance in patients with primary nephrotic syndrome]. 1996 Zhonghua Nei Ke Za Zhi pmid:9275622